Genetic influences on dynamic complexity of brain oscillations.

Abstract:

:Human electroencephalogram (EEG) consists of complex aperiodic oscillations that are assumed to indicate underlying neural dynamics such as the number and degree of independence of oscillating neuronal networks. EEG complexity can be estimated using measures derived from nonlinear dynamic systems theory. Variations in such measures have been shown to be associated with normal individual differences in cognition and some neuropsychiatric disorders. Despite the increasing use of EEG complexity measures for the study of normal and abnormal brain functioning, little is known about genetic and environmental influences on these measures. Using the pointwise dimension (PD2) algorithm, this study assessed heritability of EEG complexity at rest in a sample of 214 young female twins consisting of 51 monozygotic (MZ) and 56 dizygotic (DZ) pairs. In MZ twins, intrapair correlations were high and statistically significant; in DZ twins, correlations were substantially smaller. Genetic analyses using linear structural equation modeling revealed high and significant heritability of EEG complexity: 62-68% in the eyes-closed condition, and 46-60% in the eyes-open condition. Results suggest that individual differences in the complexity of resting electrocortical dynamics are largely determined by genetic factors. Neurophysiological mechanisms mediating genetic variation in EEG complexity may include the degree of structural connectivity and functional differentiation among cortical neuronal assemblies.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Anokhin AP,Müller V,Lindenberger U,Heath AC,Myers E

doi

10.1016/j.neulet.2005.12.025

keywords:

subject

Has Abstract

pub_date

2006-04-10 00:00:00

pages

93-8

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(05)01389-3

journal_volume

397

pub_type

杂志文章
  • A property of face representation at the categorical level.

    abstract::Face processing is unique to human beings and is likely to have special neuronal properties. We studied one of these properties, categorical representation of the face in perception processing (perception) and in memory recall processing (imagery), using the face and building stimuli. The same building-selective areas...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.09.053

    authors: Sung YW,Ogawa S

    更新日期:2008-12-19 00:00:00

  • Cerebellar granule cell survival and maturation induced by K+ and NMDA correlate with c-fos proto-oncogene expression.

    abstract::Persistent depolarization with a high K+ concentration (30 mM) or sustained activation of N-methyl-D-aspartate (NMDA) receptors (12.5 mM K+ plus 100 microM NMDA) enhance both survival and maturation of mouse cerebellar granule neurons in vitro taking as criteria the amount of protein and DNA and the release of endogen...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90790-8

    authors: Didier M,Roux P,Piechaczyk M,Verrier B,Bockaert J,Pin JP

    更新日期:1989-12-15 00:00:00

  • Amyloid beta peptides act directly on single neurons.

    abstract::A peptide consisting of residues 25-35 of the amyloid beta protein was applied to single neurons while monitoring membrane current by whole cell voltage clamp recording. Within minutes of direct exposure of a neuron to the amyloid beta peptide, a paroxysmal increase in neuronal membrane conductance was observed. This ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90519-q

    authors: Simmons MA,Schneider CR

    更新日期:1993-02-19 00:00:00

  • Effect of insulin on serotonin, 5-hydroxyindole-acetic acid, norepinephrine, epinephrine and corticosterone contents in chick.

    abstract::Pineal serotonin (5-HT), 5-hydroxyindole-acetic acid (5-HIAA), norepinephrine (NE), epinephrine (E) and adrenal corticosterone, NE and E contents were measured spectrofluorometrically 5, 15, 30 and 60 min after insulin treatment to induce hypoglycemic stress. In the pineal gland, hypoglycemic stress caused dramatic de...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90662-d

    authors: Mahata SK

    更新日期:1991-01-02 00:00:00

  • Imaging the dynamics of the auditory steady-state evoked response.

    abstract::This study used magnetoencephalography (MEG) to examine the dynamic patterns of neural activity underlying the auditory steady-state response. We examined the continuous time-series of responses to a 32-Hz amplitude modulation. Fluctuations in the amplitude of the evoked response were found to be mediated by non-linea...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.05.043

    authors: Simpson MI,Hadjipapas A,Barnes GR,Furlong PL,Witton C

    更新日期:2005-09-16 00:00:00

  • Molecular determinants of binding of a wasp toxin (PMTXs) and its analogs in the Na+ channels proteins.

    abstract::The structural specificity of alpha-PMTX, a novel peptide toxin derived from wasp venom has been studied on the neuromuscular synapse in the walking leg of the lobster. alpha-PMTX is known to induce repetitive action potentials in the presynaptic axon due to sodium channel inactivation. We synthesized 29 analogs of al...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01017-x

    authors: Konno K,Hisada M,Naoki H,Itagaki Y,Yasuhara T,Nakata Y,Miwa A,Kawai N

    更新日期:2000-05-05 00:00:00

  • Prickle promotes neurite outgrowth via the Dishevelled dependent pathway in C1300 cells.

    abstract::Murine Prickle1 and Prickle2 belong to the planar cell polarity genes. Prickle2 but not Prickle1 gene expression was induced in C1300 neuroblastoma cells during neurite-like process formation induced by retinoic acid (RA). Over-expression of Prickle1 or Prickle2 in C1300 cells induced striking neurite-like process for...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2009.09.050

    authors: Fujimura L,Watanabe-Takano H,Sato Y,Tokuhisa T,Hatano M

    更新日期:2009-12-18 00:00:00

  • Studies on single-strand scissions to cell-free plasmid DNA by the dopaminergic neurotoxin 'TaClo' (1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline).

    abstract::The DNA-damaging effect of the potent dopaminergic neurotoxin 'TaClo' (1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline) is reported. After irradiation (300 nm, 350 nm) of cell-free pBR322 DNA in the presence of TaClo, single-strand breaks were observed by gel electrophoresis. It seems likely that TaClo undergoes a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01731-1

    authors: Bringmann G,Münchbach M,Feineis D,Faulhaber K,Ihmels H

    更新日期:2001-05-18 00:00:00

  • Mortality in gerbils with repetitive ischemia: CGSGS-19755/hypothermia therapy.

    abstract::Repetitive ischemia causes more severe damage than a single insult of comparable duration. Gerbils were followed for 1 month postrepetitive ischemia and 100% mortality was demonstrated in the unprotected ischemia group by 12 days postischemia. Significant protection against mortality due to repetitive ischemia was off...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(94)90257-7

    authors: McCrea S,Shuaib A,Wishart T,Ijaz S

    更新日期:1994-03-28 00:00:00

  • Glufosinate ammonium stimulates nitric oxide production through N-methyl D-aspartate receptors in rat cerebellum.

    abstract::Glufosinate ammonium, a structural analogue of glutamate, is an active herbicidal ingredient. The neuronal activities of this compound were investigated by use of a microdialysis system that allowed us to measure nitric oxide production in the rat cerebellum in vivo. Kainate (0.3-30 nmol/10 microliter), N-methyl-D-asp...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01363-x

    authors: Nakaki T,Mishima A,Suzuki E,Shintani F,Fujii T

    更新日期:2000-09-01 00:00:00

  • Nogo-A expression in mouse central nervous system neurons.

    abstract::The longest central nervous system (CNS) specific isoform of the major myelin-associated inhibitor of neurite growth, Nogo-A, has previously been shown to be expressed largely in oligodendrocytes. Using an antibody raised against a recombinant fusion protein comprising amino acids 223-399 of Nogo-A, we show in this re...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(02)00528-1

    authors: Liu H,Ng CE,Tang BL

    更新日期:2002-08-16 00:00:00

  • Neural toxicity of retroviruses.

    abstract::Recombinant retroviruses containing the cDNA for human tyrosine hydroxylase-1 and Escherichia coli lacZ gene were used to infect primary foetal ventral mesencephalon and cortical cultures from rat brain. Severe neuronal toxicity resulted 3-4 days after infection, glial cells seemed to be much more resistant. The toxic...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(96)13224-9

    authors: Hurley MJ,Bradford HF,O'Hare K,Stern GM,Uchida K

    更新日期:1996-12-06 00:00:00

  • Prenatal D1, D1b and D3 dopamine receptor gene expression in the rat forebrain: detection by reverse polymerase chain reaction.

    abstract::Three dopamine receptor mRNAs were detected by reverse polymerase chain reaction in the rat forebrain during ontogeny. The D1 receptor mRNA gave a faint signal from gestational day 11 (G11) on, while the D1b receptor was not detectable before G12. The D3 receptor mRNA was slightly expressed at G11 and clearly present ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90680-j

    authors: Cadoret MA,Jaber M,Bloch B

    更新日期:1993-05-28 00:00:00

  • Novel microRNA revealed by systematic analysis of the microRNA transcriptome in dentate gyrus granule cells.

    abstract::Post-transcriptional control of gene expression by microRNAs provides an important regulatory system within neurons, allowing co-ordinate and fine-tuned expression of plasticity-related proteins. Indeed, specific microRNAs have been shown to be regulated by synaptic activity in the dentate gyrus, and contribute to the...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.09.003

    authors: Ryan B,Williams JM

    更新日期:2019-08-10 00:00:00

  • Circadian rhythm in metabolic activity of suprachiasmatic, supraoptic and raphe nuclei.

    abstract::Previous studies using 2-deoxyglucose (2-DG) autoradiography have demonstrated that the suprachiasmatic nucleus (SCN) of the hypothalamus, a putative neural circadian pacemaker, displays circadian rhythmicity in its metabolic activity. In the present study, we show that distinct circadian variations in 2-DG uptake occ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(85)90161-2

    authors: Rosenwasser AM,Trubowitsch G,Adler NT

    更新日期:1985-07-31 00:00:00

  • γ-Secretase and its modulators: Twenty years and beyond.

    abstract::Twenty years ago, Wolfe, Xia, and Selkoe identified two aspartate residues in Alzheimer's presenilin protein that constitute the active site of the γ-secretase complex. Mutations in the genes encoding amyloid precursor protein (APP) or presenilin (PS) cause early onset familial Alzheimer's disease (AD), and sequential...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2019.02.011

    authors: Xia W

    更新日期:2019-05-14 00:00:00

  • Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse.

    abstract::C57 black mice given a single injection of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 40 mg/kg, developed marked reduction of striatal dopamine content and loss of dopaminergic neurons in the zona compacta of the substantia nigra. However, pretreatment with any one of four different antioxidants, alpha-tocop...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(85)90229-0

    authors: Perry TL,Yong VW,Clavier RM,Jones K,Wright JM,Foulks JG,Wall RA

    更新日期:1985-09-30 00:00:00

  • Perinatal opiate treatment delays growth of cortical dendrites.

    abstract::Basilar dendritic arborizations of layer II-III pyramidal neurons in primary somatosensory cortex of 5-day-old male rats were reconstructed following perinatal morphine, morphine/naltrexone, or saline vehicle administration. Morphine treatment was observed to reduce total dendritic length. This effect was limited to h...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90444-e

    authors: Ricalde AA,Hammer RP Jr

    更新日期:1990-07-31 00:00:00

  • Coexistence of substance P and calcitonin gene-related peptide in the frog spinal cord.

    abstract::The localization of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in the untreated spinal cord of the frog using single or double immunohistochemical stainings. SP and CGRP appear to coexist in the primary afferent fibers and in the marginal and submarginal dorsal horn zones, as well as in th...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(87)90462-9

    authors: Venesio T,Mulatero B,Fasolo A

    更新日期:1987-10-05 00:00:00

  • The expanded CAG repeat associated with juvenile Huntington disease shows a common origin of most or all neurons and glia in human cerebrum.

    abstract::We have analyzed the size of the expanded poly(CAG) associated with juvenile Huntington disease in the cerebra and the cerebella of five patients. The expanded poly(CAG) was always longer in the cerebrum than in the cerebellum, but the difference in size varied from patient to patient. Except for one patient who posse...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01029-6

    authors: Kahlem P,Djian P

    更新日期:2000-06-09 00:00:00

  • Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation follow-up study.

    abstract::Transient cognitive and behavioral stabilization of patients with Alzheimer's disease (AD) is the main goal of acetylcholinesterase inhibitor (AChEI) therapy. Response to treatment is variable and it is usually assessed clinically via neuropsychological scales. Functional neuroimaging could ideally permit the objectiv...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.01.064

    authors: Ferreri F,Pasqualetti P,Määttä S,Ponzo D,Guerra A,Bressi F,Chiovenda P,Del Duca M,Giambattistelli F,Ursini F,Tombini M,Vernieri F,Rossini PM

    更新日期:2011-04-01 00:00:00

  • Transient GABA-like immunoreactive axons in the corpus callosum of perinatal rats.

    abstract::During the early postnatal development of the rat, gamma-aminobutyric acid (GABA)-like immunoreactive axons were contained within the subcortical white matter. Some of the immunoreactive axons crossed the midline, while others followed a vertical or longitudinal trajectory within the lateral part of the corpus callosu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(88)90003-1

    authors: Cobas A,Alvarez-Bolado G,Fairén A

    更新日期:1988-10-31 00:00:00

  • Recovery of function is not associated with proliferation of retinogeniculate synapses after chronic deafferentation in the dorsal lateral geniculate nucleus of the adult cat.

    abstract::A restricted recovery of visual excitation occurs in the partially deafferented dorsal lateral geniculate nucleus (dLGN) of the cat after retinal lesions. In the absence of axonal growth an increase of retinogeniculate synapses at the peripheral dendrites of deafferented cells could be a possible underlying mechanism....

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90157-5

    authors: Eysel UT,Neubacher U

    更新日期:1984-08-24 00:00:00

  • Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression.

    abstract::Basal serotonin (5-HT) release, measured in the presence of imipramine, was significantly reduced in slices of hippocampus, n. accumbens and frontal cortex from rats subjected to forced swim test and chronic isolation. Only in the hippocampus, in the two animal models of depression, K-stimulated release was increased....

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90584-8

    authors: Jaffe EH,De Frias V,Ibarra C

    更新日期:1993-11-12 00:00:00

  • Tau gene polymorphisms and apolipoprotein E epsilon4 may interact to increase risk for Alzheimer's disease.

    abstract::In an effort to analyze the genetic role of tau in Alzheimer's disease (AD), 17 polymorphisms were identified. Eleven of these polymorphisms were in complete linkage disequilibrium and segregated as two haplotypes, A and B. The A and B haplotypes were investigated in 269 AD cases and 238 controls from two different so...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00833-2

    authors: Lilius L,Froelich Fabre S,Basun H,Forsell C,Axelman K,Mattila K,Andreadis A,Viitanen M,Winblad B,Fratiglioni L,Lannfelt L

    更新日期:1999-12-17 00:00:00

  • Inhibitory action of acetylcholine, baclofen and GTP-gamma-S on calcium channels in adult rat sensory neurons.

    abstract::High- and low-voltage activated calcium channel currents (HVA and LVA) were inhibited by acetylcholine (10-100 microM) and baclofen (10 microM) in adult rat sensory neurons. This modulatory effect was present on dihydropyridine (nifedipine 1 microM) and/or omega-conotoxin (3.2 microM, 2-5 h incubation) insensitive com...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90630-c

    authors: Formenti A,Sansone V

    更新日期:1991-10-14 00:00:00

  • Prefrontal gray matter increases in healthy individuals after lithium treatment: a voxel-based morphometry study.

    abstract::The objective of this study was to test the hypothesis that 4 weeks of lithium administration would be associated with changes in brain gray and white matter volumes in healthy individuals. Thirteen right-handed healthy volunteers (6 females, mean age=25.9+/-10.0 years) were studied. 3D SPGR MRIs (TR=25 ms, TE=5 ms, s...

    journal_title:Neuroscience letters

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.neulet.2007.09.074

    authors: Monkul ES,Matsuo K,Nicoletti MA,Dierschke N,Hatch JP,Dalwani M,Brambilla P,Caetano S,Sassi RB,Mallinger AG,Soares JC

    更新日期:2007-12-11 00:00:00

  • N-methyl-D-aspartate receptor and L-type voltage-gated Ca2+ channel activation mediate proline-rich tyrosine kinase 2 phosphorylation during cerebral ischemia in rats.

    abstract::Cerebral ischemia induces rapid efflux of glutamate into the extracellular space contributing to excessive activation of glutamate receptors in postsynaptic cells, particularly N-methyl-D-aspartate (NMDA) receptors, which triggers the neuron lesion through calcium overload. Our studies indicated that cerebral ischemia...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2003.10.076

    authors: Guo J,Meng F,Fu X,Song B,Yan X,Zhang G

    更新日期:2004-01-30 00:00:00

  • Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells.

    abstract::This study was designed to investigate the effects of honokiol, a neuroprotective agent, on cerebral edema in cerebral ischemia reperfusion (IR) mice and its mechanism of anti-inflammation. Honokiol (0.7-70μg/kg) significantly reduced brain water contents and decreased the exudation of Evans blue dye from brain capill...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.11.052

    authors: Zhang P,Liu X,Zhu Y,Chen S,Zhou D,Wang Y

    更新日期:2013-02-08 00:00:00

  • The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease.

    abstract::The neuropathological hallmarks of Alzheimer's disease (AD) include the presence of extracellular amyloid-beta peptide (Abeta) in the form of amyloid plaques in the brain parenchyma and neuronal loss. The mechanism associated with neuronal death by amyloid plaques is unclear but oxidative stress and glial activation h...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.06.045

    authors: Lee HJ,Lee JK,Lee H,Shin JW,Carter JE,Sakamoto T,Jin HK,Bae JS

    更新日期:2010-08-30 00:00:00