Acetylcholine excites identified septo-hippocampal neurons in the rat.

Abstract:

:Neurons of the medial septum-nucleus of the diagonal band of Broca (vertical limb) area were identified as septo-hippocampal neurons by antidromic electrical activation in anesthetized rats. A large majority of these presumably cholinergic neurons could be excited by the iontophoretic application of acetylcholine or cholinergic agonists such as carbachol. The acetylcholine-induced excitations were readily antagonized by atropine. These results suggest that cholinergic neurons can be excited by their own transmitter, i.e. acetylcholine.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Dutar P,Lamour Y,Jobert A

doi

10.1016/0304-3940(83)90126-x

subject

Has Abstract

pub_date

1983-12-23 00:00:00

pages

43-7

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(83)90126-X

journal_volume

43

pub_type

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