Differential distribution of GABAA receptor mRNAs in bovine cerebellum--localization of alpha 2 mRNA in Bergmann glia layer.

abstract：:Horseradish peroxidase (HRP), injected into the rat caudal medulla oblongata, was detected by immunoperoxidase staining in 120 microns frozen sections, allowing examination of both the distribution and morphology of transporting neurons. In the hypothalamus, several groups of HRP-labeled neurons could be distinguished...

journal_title：Neuroscience letters

authors： Sofroniew MV,Schrell U

更新日期：1980-10-02 00:00:00

abstract：:The purpose of the present study was to confirm the functional regulation by alpha 2-adrenoceptors of the release of serotonin (5-HT) from the rat hippocampus in vivo. Under several pharmacological conditions, extracellular levels of 5-HT were estimated by assaying its concentrations in the perfusate by high performan...

journal_title：Neuroscience letters

authors： Numazawa R,Yoshioka M,Matsumoto M,Togashi H,Kemmotsu O,Saito H

更新日期：1995-06-16 00:00:00

abstract：:Estrogen was shown to promote neuronal survival against several neurotoxic insults including β-amyloid (Aβ). The proposed mechanism includes the activation of the mitogen activated protein kinase/extracellular signal-regulated kinase (Mapk/Erk), phosphatidylinositol 3-kinase/Akt pathways and the upregulation of antiap...

journal_title：Neuroscience letters

authors： Mateos L,Persson T,Katoozi S,Gil-Bea FJ,Cedazo-Minguez A

更新日期：2012-01-11 00:00:00

abstract：:The association of alpha-synuclein (alpha-syn) neuropathology with Parkinson's disease (PD) and several related disorders has led to an intense research effort to develop cerebrospinal fluid (CSF)- or blood-based alpha-syn biomarkers for these types of diseases. Recent studies show that alpha-syn is present in CSF and...

journal_title：Neuroscience letters

authors： Ohrfelt A,Grognet P,Andreasen N,Wallin A,Vanmechelen E,Blennow K,Zetterberg H

更新日期：2009-02-06 00:00:00

abstract：:Rats were treated with once-daily subcutaneous injections of atropine or normal saline for 10 days. Cryostat sections of fresh-frozen brain were subjected to quantitative muscarinic receptor ([3H]quinuclidinylbenzilate (QNB)) binding autoradiography, and quantitative in-situ hybridization autoradiography for beta-amyl...

journal_title：Neuroscience letters

authors： Beach TG,Walker DG,Cynader MS,Hughes LH

更新日期：1996-05-24 00:00:00

abstract：:The potassium conductance (gK) blockers tetraethylammonium (TEA) and 4-aminopyridine (4-AP) strongly excited experimental neuromas that had spontaneous discharge, but had minimal effects on acutely cut nerves and on old, quiescent neuromas. Resting gK apparently moderates hyperexcitability in active neuromas. ...

journal_title：Neuroscience letters

authors： Devor M

更新日期：1983-09-30 00:00:00

abstract：:We investigated glutamate-induced neuron response in the ventral nerve cord of the earthworm (Eisenia foetida) using a voltage-sensitive dye-imaging technique. Isolated earthworm ganglia were stained by fluorescence voltage-sensitive dye, RH414, and voltage image was acquired by a conventional charge-coupled device (C...

journal_title：Neuroscience letters

authors： Oka K,Ogawa H,Fujita S

更新日期：1994-09-26 00:00:00

abstract：:Facilitation of synaptic connections between sensory neurons and motor neurons mediating the tail-withdrawal reflex in Aplysia is produced by sensitizing stimuli. These effects can be mimicked by perfusing the pleural and pedal ganglia of a semi-intact preparation with serotonin (5-HT). In addition to the synaptic fac...

journal_title：Neuroscience letters

authors： Walsh JP,Byrne JH

更新日期：1984-11-23 00:00:00

abstract：:We previously reported that the amyloid-beta protein (Abeta) reduces the synthesis of acetylcholine (ACh) in a mouse septal cell line, SN56, without causing death of the cells. Here, we report that the ACh-reducing effect of either Abeta 1-28 or Abeta 1-42 (100 nM; 48 h) in SN56 cells can be prevented by a co-treatmen...

journal_title：Neuroscience letters

authors： Pedersen WA,Blusztajn JK

更新日期：1997-12-19 00:00:00

abstract：:To study zinc (Zn) mobility in the rat olfactory tract, brain distribution of 65Zn after injection into the olfactory bulb or amygdaloid nuclei was analyzed by autoradiography. Twenty-four hours after 65Zn injection into the olfactory bulb, 65Zn was distributed in the ipsilateral piriform cortex, amygdaloid nuclei and...

journal_title：Neuroscience letters

authors： Takeda A,Ohnuma M,Sawashita J,Okada S

更新日期：1997-03-28 00:00:00

abstract：:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain t...

journal_title：Neuroscience letters

authors： Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

更新日期：2008-08-08 00:00:00

abstract：:Interleukin-1 (IL-1) mediates numerous responses on the mouse anterior pituitary cell line AtT-20. We have studied the ligand binding properties of the IL-1 receptors (IL-1R) of the AtT-20 cells and found that they possess 1.5 x 10(3) receptors/cell with a Kd of 0.15 nM for [125I]IL-1 alpha. Using oligonucleotide prim...

journal_title：Neuroscience letters

authors： Bristulf J,Simoncsits A,Bartfai T

更新日期：1991-07-22 00:00:00

abstract：:It is well-established that 17beta-estradiol (17beta-E(2)) confers neuroprotection to male and female rats exposed to focal cerebral ischemia, while less is known about the effects of the hormone under conditions of transient global ischemia. Since translocation of cytochrome c from the mitochondria to the cytosol is ...

journal_title：Neuroscience letters

authors： Bagetta G,Chiappetta O,Amantea D,Iannone M,Rotiroti D,Costa A,Nappi G,Corasaniti MT

更新日期：2004-09-16 00:00:00

abstract：:The study investigated the effects of metabolic syndrome on urinary bladder nerve-growth factor (NGF) and p75(NTR) expression in fructose-fed obese rats. Age-matched male Wistar rats were divided into four groups; group I: normal control rats; group II: 6-week fructose-fed rats (FR); group III: 9-week FR; and group IV...

journal_title：Neuroscience letters

authors： Cheng JT,Tong YC

更新日期：2008-08-15 00:00:00

abstract：:The effects of caloric restriction (CR) on cognition and behavior in developing mice were investigated in this study. Male and female Kunmin mice were fed a standard rodent diet ad libitum (Control); 80% of control (20% CR) or 65% of control (35% CR) for 6 months. Body weight gain was significant reduced in CR mice re...

journal_title：Neuroscience letters

authors： Wu A,Sun X,Liu Y

更新日期：2003-03-20 00:00:00

abstract：:Cochlear hair cell loss results in the secondary loss of spiral ganglion cells (SGCs). The death of these SGCs is due to apoptosis. The E2F1-cyclin dependent kinase 1 (CDK1) pathway is believed to represent an important mechanism of neuronal cell death. However, the role of this pathway in spiral ganglion neuronal apo...

journal_title：Neuroscience letters

authors： Liu YY,Wang GP,Peng Z,Guo JY,Wu Q,Xie J,Gong SS

更新日期：2016-03-23 00:00:00

abstract：:The role of G-proteins in the mediation of the cardiovascular effects of neuropeptide Y and the alpha 2-adrenoceptor agonist clonidine was investigated by injections of pertussis toxin (10 micrograms/30 microliters, i.v.t., 24 h) in the awake unrestrained male rat. Treatment with pertussis toxin was found to inhibit t...

journal_title：Neuroscience letters

authors： Fuxe K,von Euler G,van der Ploeg I,Fredholm BB,Agnati LF

更新日期：1989-07-03 00:00:00

abstract：:The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter release and in synaptogenesis, suggesting a potential role in several neuropsychiatric diseases. The human SYN3 gene is located on chromosome 22q12-13, a candidate...

journal_title：Neuroscience letters

authors： Chen Q,Che R,Wang X,O'Neill FA,Walsh D,Tang W,Shi Y,He L,Kendler KS,Chen X

更新日期：2009-11-20 00:00:00

abstract：:It is known that the number of newly generated neurons is increased in the young and adult rodent subventricular zone (SVZ) and dentate gyrus (DG) after transient brain ischemia. However, it remains unclear whether increase in neurogenesis in the adult DG induced by ischemic stroke is transient or sustained. We here r...

journal_title：Neuroscience letters

authors： Wang C,Zhang M,Sun C,Cai Y,You Y,Huang L,Liu F

更新日期：2011-01-13 00:00:00

abstract：:The goal of this study was to examine the coupling between visual information and body sway with binocular and monocular vision at two distances from the front wall of a moving room. Ten participants stood as still as possible inside of a moving room facing the front wall in conditions that combined room movement with...

journal_title：Neuroscience letters

authors： Moraes R,Lopes AG,Barela JA

更新日期：2009-09-04 00:00:00

abstract：:Electroencephalography (EEG) is a non-invasive technique for monitoring electrical activity and has good time resolution. Combining these advantages of EEG with dipole-tracing analysis incorporating a realistic three-layer head model (scalp-skull-brain head model; SSB/DT) allows for the detection of dipoles in the mil...

journal_title：Neuroscience letters

authors： Inoue M,Masaoka Y,Kawamura M,Okamoto Y,Homma I

更新日期：2008-05-30 00:00:00

abstract：:Recent findings indicated that the excitotoxicity of glutamate analogues was prevented in the mammalian nervous system by N-methyl-D-aspartate (NMDA) antagonists. The neurodegenerative effects of kainic acid, and the putative protection of MK-801 and 6,7-dinitroquinoxaline-2,3-dione (DNQX), were investigated by morpho...

journal_title：Neuroscience letters

authors： Villani L,Carraro S,Guarnieri T

更新日期：1995-06-09 00:00:00

abstract：:The p11 protein (also called S100A10), which plays a pivotal role in the dynamic modulation of serotonergic 1B receptor function, has been implicated in the pathogenesis of major depressive disorder (MDD) and the therapeutic mechanisms of antidepressant action. Humans and mice with depression have lower central p11 le...

journal_title：Neuroscience letters

authors： Tzang RF,Hong CJ,Liou YJ,Yu YW,Chen TJ,Tsai SJ

更新日期：2008-12-05 00:00:00

abstract：:Ribonuclease protection assays were performed on the basal hypothalamus (BH), the preoptic area (POA) and the thalamus (THAL) from female guinea pigs that were ovariectomized and implanted with morphine (n = 8) or placebo (n = 8) pellets for 1 week. An antisense [32P]rUTP labeled riboprobe, representing a 280 bp fragm...

journal_title：Neuroscience letters

authors： Rønnekleiv OK,Bosch MA,Cunningham MJ,Wagner EJ,Grandy DK,Kelly MJ

更新日期：1996-09-27 00:00:00

abstract：:The dorsal visual processing stream that includes V1, motion sensitive area V5 and the posterior parietal lobe, supports visually guided motor function. Two recent studies have reported associations between global motion perception, a behavioural measure of processing in V5, and motor function in pre-school and school...

journal_title：Neuroscience letters

authors： Thompson B,McKinlay CJD,Chakraborty A,Anstice NS,Jacobs RJ,Paudel N,Yu TY,Ansell JM,Wouldes TA,Harding JE,CHYLD Study Team.

更新日期：2017-09-29 00:00:00

abstract：:Confocal immunohistochemistry shows that neurotrophin-3 (NT-3) and its receptor tropomyosin-related tyrosin kinase C (trkC) are present in both neonatal (P6) and adult (P45) mouse motor nerve terminals in neuromuscular junctions (NMJ) colocalized with several synaptic proteins. NT-3 incubation (1-3h, in the range 10-2...

journal_title：Neuroscience letters

authors： Garcia N,Santafé MM,Tomàs M,Lanuza MA,Besalduch N,Tomàs J

更新日期：2010-04-05 00:00:00

abstract：:Hypoxic encephalopathy is a common cause of neonatal seizures and long-term neurological cognitive deficits. In rats at postnatal days 10-12 (P10-P12), global hypoxia induced spontaneous seizures and chronic brain injury, mimicking clinical aspects of neonatal hypoxia. Synaptic Ras-GTPase activating protein (SynGAP) h...

journal_title：Neuroscience letters

authors： Yang SN,Huang CB,Yang CH,Lai MC,Chen WF,Wang CL,Wu CL,Huang LT

更新日期：2004-11-16 00:00:00

abstract：:Super-resolution microscopy techniques offer subdiffraction limited resolution that is two- to ten-fold improved compared to that offered by conventional confocal microscopy. This breakthrough in resolution for light microscopy has contributed to new findings in neuroscience and synapse biology. This review will focus...

journal_title：Neuroscience letters

authors： Badawi Y,Nishimune H

更新日期：2020-01-10 00:00:00

abstract：:The streptozotocin (STZ)-induced diabetes model is widely used for the induction of neuropathy in the rat. In this model, diabetic animals often display chronic illness, which raises objections not only on ethical but also on scientific grounds. In this study, the investigators set out to determine the impact of bodyw...

journal_title：Neuroscience letters

authors： Hoybergs YM,Biermans RL,Meert TF

更新日期：2008-05-02 00:00:00

abstract：:We have studied electrophysiologically the actions of gamma-aminobutyric acid (GABA) and related pharmacological agents on fish retinal horizontal cells by recording intracellularly from isolated retinae perfused with Ringer containing the various drugs. We show that although GABA usually hyperpolarizes the membrane p...

journal_title：Neuroscience letters

authors： Hankins MW,Ruddock KH

更新日期：1984-01-27 00:00:00