Abstract:
:The effects of free fatty acids (FFAs) on growth hormone releasing hormone (GHRH) secretion by fetal rat cortical and hypothalamic neurons in monolayer culture have been investigated. Treatment with caprylic or oleic acids for 90 min, induced a dose-dependent increase in GHRH secretion. The stimulatory effect of caprylic acid was time-dependent, being present after 90 min and 5 h but not after 24 h. Finally, GHRH release induced by 56 mM KCl or by the calcium ionophore A23187 was not modified by 5 x 10(-3) M caprylic acid. These data support a role for FFAs on GHRH secretion.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Señaris RM,Lewis MD,Lago F,Dominguez F,Scanlon MF,Dieguez Cdoi
10.1016/0304-3940(92)90140-3keywords:
subject
Has Abstractpub_date
1992-01-20 00:00:00pages
80-2issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(92)90140-3journal_volume
135pub_type
杂志文章abstract::The mechanisms underlying aggregate formation in age-related neurodegenerative diseases remain not well understood. Here we investigated whether dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (Dyrk1A) is involved in the formation of regulator of calcineurin 1 (RCAN1) aggregates. We show that RCAN1 s...
journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
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更新日期:1982-12-30 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(92)90026-4
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90290-8
更新日期:1984-07-13 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2007-09-25 00:00:00
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journal_title:Neuroscience letters
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更新日期:2009-05-29 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.03.023
更新日期:2012-04-25 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2001-05-18 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.07.027
更新日期:2012-09-06 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.04.035
更新日期:2004-07-15 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)12144-7
更新日期:1995-12-08 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2020.134774
更新日期:2020-04-01 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90100-8
更新日期:1991-04-01 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90424-7
更新日期:1988-02-15 00:00:00
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journal_title:Neuroscience letters
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更新日期:2000-08-11 00:00:00
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journal_title:Neuroscience letters
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pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
abstract::Central diabetes insipidus can occur after hypothalamic-hypophyseal tract injury. This injury is linked with a deficit in circulating vasopressin and oxytocin, which are produced in the supraoptic nuclei and the hypothalamic paraventricular nuclei. Previous studies indicate that an ectopic neural lobe forms after pitu...
journal_title:Neuroscience letters
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更新日期:2018-04-23 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1983-06-30 00:00:00
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更新日期:1995-04-07 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1999-08-27 00:00:00
abstract:OBJECT:Much evidence has demonstrated that stress and tumor interact, but the mechanisms are poorly understood. The purpose of this study is to discuss the effect of unpredictable chronic mild stress (CMS) upon the behavior of Walker 256 tumor-bearing rats and its mechanism. METHODS:Observe the effects of CMS on the s...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2009.06.031
更新日期:2010-03-31 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90665-9
更新日期:1988-12-19 00:00:00
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journal_title:Neuroscience letters
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更新日期:2003-02-13 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(90)90700-j
更新日期:1990-01-01 00:00:00
abstract::Synthetic soluble Aβ oligomers are often used as a surrogate for biologic material in a number of model systems. We compared the activity of Aβ oligomers (synthetic and cell culture media derived) on the human SH-SY5Y neuroblastoma and C2C12 mouse myoblast cell lines in a novel, modified MTT assay. Separating oligomer...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2011-06-15 00:00:00