Oleamide attenuates apoptotic death in cultured rat cerebellar granule neurons.

abstract：:The present study has described and quantitated the distribution of mu-opioid receptors in the nucleus raphe magnus (NRM) and nucleus gigantocellularis (NGC), using in vitro autoradiography. Moderately dense binding of a mu-enkephalin analog, DAGO, was observed in the NRM and adjacent parts of the NGC. DAGO binding de...

journal_title：Neuroscience letters

authors： Bowker RM,Dilts RP

更新日期：1988-06-07 00:00:00

abstract：:The processing of sound information is mediated by the cochlea and the central auditory system. Among the central auditory system, the inferior colliculus (IC) has leading roles in the acoustic processing. In a previous study, we demonstrated psychiatric disorder-related behavioral abnormalities in a genetically modif...

journal_title：Neuroscience letters

authors： Nakajima M,Nishikawa C,Miyasaka Y,Kikkawa Y,Mori H,Tsuruta M,Okuyama S,Furukawa Y

更新日期：2014-04-30 00:00:00

abstract：:Physiological and histochemical studies have clearly demonstrated the control and innervation of the sympathetic nerve on the splanchnic veins. However, the origins of postganglionic fibers remain to be determined. In this study, we used the retrograde transport of horseradish peroxidase (HRP) technique to trace the o...

journal_title：Neuroscience letters

authors： Chen HI,Kang BH,Wang JY,Tseng YL

更新日期：1994-05-23 00:00:00

abstract：:The vestibular system has widespread interactions with other sensory modalities. Here we investigate whether vestibular stimulation modulates somatosensory function, by assessing the ability to detect faint tactile stimuli to the fingertips of the left and right hand with or without galvanic vestibular stimulation (GV...

journal_title：Neuroscience letters

authors： Ferrè ER,Day BL,Bottini G,Haggard P

更新日期：2013-08-29 00:00:00

abstract：:Recent research in social neuroscience proposes a link between mirror neuron system (MNS) and social cognition. The MNS has been proposed to be the neural mechanism underlying action recognition and intention understanding and more broadly social cognition. Pre-motor MNS has been suggested to modulate the motor cortex...

journal_title：Neuroscience letters

authors： Puzzo I,Cooper NR,Vetter P,Russo R,Fitzgerald PB

更新日期：2009-12-25 00:00:00

abstract：:Kainic acid binding was measured in crude membrane fractions prepared from postmortem human caudate tissue of control persons and patients afflicted with Huntington's disease. A significant reduction in binding sites with no change in affinity was found in the Huntington's tissue, the apparent dissociation constants (...

journal_title：Neuroscience letters

authors： Henke H

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Akathisia is characterized by restlessness and crawling sensations similar to restless legs syndrome (RLS). Long latency flexor reflex (LLFR) which has helped to advance RLS pathophysiology has never been investigated in akathisia. Due to the clinical commonalities of akathisia and RLS, we inve...

journal_title：Neuroscience letters

authors： Gunduz A,Metin B,Metin SZ,Poyraz BC,Karadeniz D,Kiziltan G,Kiziltan ME

更新日期：2017-02-22 00:00:00

abstract：:Morphine injections in 16-day-old rats caused an increase in norepinephrine concentration in both superior cervical ganglion and iris after 1 h. Although the increase in the ganglion was blocked by naloxone pretreatment, the increase in the iris was not prevented. The morphine-induced increase did not require the pres...

journal_title：Neuroscience letters

authors： Mattio TG,Kirby ML

更新日期：1983-09-09 00:00:00

abstract：:The medial prefrontal cortex (mPFC) is thought to exert inhibitory control over stress-induced activation of the amygdala and neurocognitive effects. As evidence to support this, we examined how exposure to either a brief or prolonged stress affected on amygdalar c-Fos levels and recognition memory of animals with mPF...

journal_title：Neuroscience letters

authors： Park JC,Jeon YJ,Kim JJ,Cho J,Choi DH,Han JS

更新日期：2020-09-14 00:00:00

abstract：:The functional connections between corticospinal neurones and motor units of the monkey's hand muscles were investigated by constructing cross-correlograms of activity recorded from pyramidal tract neurones and from single motor units in the contralateral thenar muscles during performance of a precision grip between t...

journal_title：Neuroscience letters

authors： Mantel GW,Lemon RN

更新日期：1987-06-01 00:00:00

abstract：:Noise-induced hearing loss (NIHL) severely impacts the quality of life of affected individuals. Oxidative stress resulting from noise exposure is a significant cause of NIHL. Although histone deacetylase (HDAC) inhibitors were shown to protect against NIHL, the underlying mechanism remains unclear, and it is not known...

journal_title：Neuroscience letters

authors： Yang DH,Xie J,Liu K,Peng Z,Guo JY,Yu SK,Wang GP,Gong SS

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a subcortical, inherited, cerebral small vessel disease. Several studies have revealed the involvement of specific cortical regions. However, the structural brain alterations and their clinical correlation...

journal_title：Neuroscience letters

authors： Pan H,Huang Q,Ban S,Du X,Su J,Liu J

更新日期：2020-11-01 00:00:00

abstract：:We assess in mice, the electrophysiological criteria developed in humans and rats in vivo for unmyelinated (C) fibre differentiation into sub-classes, derived from the activity-induced latency increase ("slowing") in response to electrical stimulation during 6 min at 0.25 Hz followed by 3 min at 2 Hz. Fibres are consi...

journal_title：Neuroscience letters

authors： Hoffmann T,De Col R,Messlinger K,Reeh PW,Weidner C

更新日期：2015-04-10 00:00:00

abstract：:beta-N-Oxalylamino-L-alanine (BOAA) and beta-N-methylamino-L-alanine (BMAA) were tested for their ability to produce acute excitotoxicity in in embryonic chick retina. gamma-Aminobutyric acid (GABA) release and histology were monitored in retina treated with various concentrations of BOAA, BMAA, kainate (KA), N-methyl...

journal_title：Neuroscience letters

authors： Zeevalk GD,Nicklas WJ

更新日期：1989-07-31 00:00:00

abstract：:Hrk, a regulator of cell death, belongs to the family of pro-apoptotic BH3-only proteins and is known to induce apoptosis in nerve tissue. We examined Hrk gene expression to clarify the role of BH3-only proteins in apoptosis of retinal ganglion cells (RGCs) after optic nerve transection in the adult rat. Reverse trans...

journal_title：Neuroscience letters

authors： Wakabayashi T,Kosaka J,Hommura S

更新日期：2002-01-25 00:00:00

abstract：:The beta-carbolines, methyl-beta-carboline-3-carboxylate (beta-CCM) and 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM) are known to have pharmacological properties opposite to those of agonistic benzodiazepines. Convulsions induced by these drugs lead to differential patterns, such as clonus, myoclonic or t...

journal_title：Neuroscience letters

authors： Martin B,Desforges C,Chapouthier G

更新日期：1991-11-25 00:00:00

abstract：:This study examined the effects of anterior pretectal nucleus (APT) conditioning stimulation on the activity of 92 functionally identified somatosensory brainstem neurons in the trigeminal (V) subnuclei oralis, interpolaris and caudalis of anesthetized rats. Conditioning stimulation inhibited most of the nociceptive n...

journal_title：Neuroscience letters

authors： Chiang CY,Chen IC,Dostrovsky JO,Sessle BJ

更新日期：1992-01-06 00:00:00

abstract：:Previous studies have showed that SIN-1, a nitric oxide (NO) donor, injected into the dorsolateral column of the periaqueductal gray (dlPAG) induces flight reactions. This drug, however, can also produce peroxynitrite, which may interfere in this effect. In addition, it is also unknown if this effect is mediated by lo...

journal_title：Neuroscience letters

authors： Braga AA,Aguiar DC,Guimarães FS

更新日期：2009-08-07 00:00:00

abstract：:Alzheimer's disease (AD) brains contain high levels of advanced glycation endproducts (AGEs). Double immunostaining using anti-AGE and anti-apolipoprotein E (apoE) antibodies demonstrated that AGEs co-localized to a very high degree with apoE. We examined the binding of apoE to in vitro-prepared AGE-bovine serum album...

journal_title：Neuroscience letters

authors： Li YM,Dickson DW

更新日期：1997-05-02 00:00:00

abstract：:To assess the significance of the association between apolipoprotein E (APOE) epsilon 4 allele and amyloid beta-peptide (A-beta) deposits in the brain, we performed APOE-genotyping and measured the density of A-beta deposits, neuritic plaques and neurofibrillary tangles in 27 cases from the Charles Foix clinico-pathol...

journal_title：Neuroscience letters

authors： Berr C,Hauw JJ,Delaère P,Duyckaerts C,Amouyel P

更新日期：1994-09-12 00:00:00

abstract：:The effects of the group III mGluR agonist, L-2-amino-4-phosphonobutyrate (L-AP4), on depolarization-stimulated cGMP levels in adult rat cerebellar slices were determined. L-AP4 elicited a concentration-dependent, complete inhibition of cGMP formation stimulated by 4-aminopyridine (4-AP; 1 mM), yielding an IC50 value ...

journal_title：Neuroscience letters

authors： Cartmell J,Kemp JA,Mutel V

更新日期：1997-06-13 00:00:00

abstract：:The aim of the present study was to investigate the moderating effect of intolerance of uncertainty (IU) on exposure to aversion and its anticipation using event-related potentials (ERPs). Sixteen subjects high in IU and 16 subjects low in IU underwent an affective cueing paradigm where a warning cue signaled the vale...

journal_title：Neuroscience letters

authors： Gole M,Schäfer A,Schienle A

更新日期：2012-01-24 00:00:00

abstract：:Fluorescent tracers (Nuclear Yellow, True Blue, Fast Blue) were injected, in various combinations, into the globus pallidus and substantia nigra in three marmosets. Examination of perikarya in the ipsilateral neostriatum, well removed from pallidal injection sites, revealed that the predominant pattern was of single-l...

journal_title：Neuroscience letters

authors： Féger J,Crossman AR

更新日期：1984-08-24 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP22) gene which results in an abnormal myelination of its peripheral nervous system. The recent identification of two different PMP22 mRNA differing in their 5' non-translated region led us to monitor their respectiv...

journal_title：Neuroscience letters

authors： Garbay B,Boiron-Sargueil F,Cassagne C

更新日期：1995-10-06 00:00:00

abstract：:Findings from preclinical and clinical research support the involvement of central noradrenergic dysregulation in the etiology of attention deficit hyperactivity disorder (ADHD). Previous studies have suggested that the alpha-2C-adrenergic receptor gene (ADRA2C) is associated with ADHD. The aims of this study were to ...

journal_title：Neuroscience letters

authors： Cho SC,Kim JW,Kim BN,Hwang JW,Shin MS,Park M,Kim SA,Cho DY,Yoo HJ,Chung US,Son JW,Park TW

更新日期：2008-12-03 00:00:00

abstract：:The specific mRNA of myelin basic protein (MBP) was isolated from active myelinating rat brains. The isolated mRNA was able to direct the synthesis of immunochemically detectable MBP in a wheat-germ cell free protein synthesis system. There was, however, no evidence of neuronal translational control of the in vitro MB...

journal_title：Neuroscience letters

authors： Fan K

更新日期：1982-03-17 00:00:00

abstract：:In an attempt to elucidate the possible mechanisms involved in the development of the thermoregulatory disturbances induced by systemic capsaicin treatment, the effects of 5-HT injected into the preoptic region or into the cisterna magna on the body temperature and on tail skin vasodilation were studied in control and...

journal_title：Neuroscience letters

authors： Hajós M,Obál F Jr,Jancsó G,Obál F

更新日期：1985-02-28 00:00:00

abstract：:Fibroblasts from Alzheimer's disease (AD) patients displayed decreased cytochrome c oxidase (complex IV) activity (P < 0.05). The basal oxygen consumption rate (QO2) and the response to an uncoupler of oxidative phosphorylation did not differ between AD and control fibroblasts. The QO2 of AD fibroblasts was more susce...

journal_title：Neuroscience letters

authors： Curti D,Rognoni F,Gasparini L,Cattaneo A,Paolillo M,Racchi M,Zani L,Bianchetti A,Trabucchi M,Bergamaschi S,Govoni S

更新日期：1997-10-24 00:00:00

abstract：:Brain pericytes are involved in neurovascular dysfunction, neurodegeneration and/or neuroinflammation. In the present study, we focused on the proinflammatory properties of brain pericytes to understand their participation in the induction of inflammation at the neurovascular unit (NVU). The NVU comprises different ce...

journal_title：Neuroscience letters

authors： Matsumoto J,Takata F,Machida T,Takahashi H,Soejima Y,Funakoshi M,Futagami K,Yamauchi A,Dohgu S,Kataoka Y

更新日期：2014-08-22 00:00:00

abstract：:Many studies have shown that minocycline, an antibacterial tetracycline, suppresses experimental pain. While minocycline's positive effects on pain resolution suggest that clinical use of such drugs may prove beneficial, minocycline's antibiotic actions and divalent cation (Ca(2+); Mg(2+)) chelating effects detract fr...

journal_title：Neuroscience letters

authors： Bastos LF,Godin AM,Zhang Y,Jarussophon S,Ferreira BC,Machado RR,Maier SF,Konishi Y,de Freitas RP,Fiebich BL,Watkins LR,Coelho MM,Moraes MF

更新日期：2013-05-24 00:00:00