Cross-correlation reveals facilitation of single motor units in thenar muscles by single corticospinal neurones in the conscious monkey.

abstract：:Expression levels of amyloid beta (Abeta)-degrading enzymes, insulin degrading enzyme (IDE) and neprilysin (NEP), were examined in transgenic mice with Alzheimer's disease-like neuropathology. After the development of first Abeta plaques in transgenic mice brain, cortical mRNA and protein levels of IDE were significan...

journal_title：Neuroscience letters

authors： Vepsäläinen S,Hiltunen M,Helisalmi S,Wang J,van Groen T,Tanila H,Soininen H

更新日期：2008-06-20 00:00:00

abstract：:Infarct volume and immunoreactivities for trkB and trkC in rat brain were compared at 24 h after 90 min of transient middle cerebral artery occlusion (MCAO) between animal groups with or without neurotrophin-3 (NT-3, 10 microg/250 g animal). Treatment of rat brain with topical application of NT-3 significantly reduced...

journal_title：Neuroscience letters

authors： Zhang WR,Hayashi T,Wang JM,Sasaki C,Sakai K,Warita H,Shiro Y,Suenaga H,Ohmae H,Tsuji S,Itoh T,Nishimura O,Nagasaki H,Abe K

更新日期：1999-12-10 00:00:00

abstract：:A trait locus for electroencephalographic photoparoxysmal response (PPR) has been mapped to the chromosomal region 6p21 near a susceptibility locus for juvenile myoclonic epilepsy (JME). Linkage disequilibrium mapping revealed strong associations between JME and polymorphisms of the gene encoding the bromodomain-conta...

journal_title：Neuroscience letters

authors： Lorenz S,Taylor KP,Gehrmann A,Becker T,Muhle H,Gresch M,Tauer U,Sander T,Stephani U

更新日期：2006-05-29 00:00:00

abstract：:The p11 protein (also called S100A10), which plays a pivotal role in the dynamic modulation of serotonergic 1B receptor function, has been implicated in the pathogenesis of major depressive disorder (MDD) and the therapeutic mechanisms of antidepressant action. Humans and mice with depression have lower central p11 le...

journal_title：Neuroscience letters

authors： Tzang RF,Hong CJ,Liou YJ,Yu YW,Chen TJ,Tsai SJ

更新日期：2008-12-05 00:00:00

abstract：:Odor-induced oscillatory signals have been reported in odor discrimination in various insects. To understand dynamic olfactory coding in the first order olfactory center, the antennal lobe, localization of oscillatory signals was investigated using an optical recording technique with a voltage-sensitive dye. We presen...

journal_title：Neuroscience letters

authors： Okada K,Kanzaki R

更新日期：2001-12-28 00:00:00

abstract：:Granule neurons from the rat dentate gyrus were acutely isolated and whole-cell currents recorded. Maximal enhancement of 7 microM gamma-aminobutyric acid (GABA; EC30) evoked currents was obtained with 100 microM pentobarbital where the peak-current was 2.1+/-0.2 of control. One hundred microM pentobarbital alone evok...

journal_title：Neuroscience letters

authors： Lim MS,Lindquist CE,Birnir B

更新日期：2003-12-19 00:00:00

abstract：:In the presence of atropine electrical transmural stimulation (using repetitive volleys, e.g. 3 pulses at 50 Hz applied every 4 s) of full thickness longitudinal strips of guinea-pig ileum produced non-cholinergic excitatory junction potentials (EJPs) and inhibitory junction potentials (IJPs) in the circular muscle la...

journal_title：Neuroscience letters

authors： Taylor GS,Bywater RA

更新日期：1986-01-02 00:00:00

abstract：:To verify the hypothesis that the control of movement by the cortical masticatory area (CMA) is particularly important at the beginning of the mastication, we compared movements before and after bilateral CMA ablation. After ablation, the animal could not manipulate food placed in the front of the mouth for several da...

journal_title：Neuroscience letters

authors： Enomoto S,Schwartz G,Lund JP

更新日期：1987-11-23 00:00:00

abstract：:Conduction velocities of antidromically evoked impulses along the goldfish Mauthner axon were found to be inversely correlated with body length. To test the hypothesis that such a relation is accompanied by a reduction in axonal diameter with increasing fish size, Mauthner axon diameters were measured. A parabolic rel...

journal_title：Neuroscience letters

authors： Funch PG,Kinsman SL,Faber DS,Koenig E,Zottoli SJ

更新日期：1981-12-11 00:00:00

abstract：:The effects of i.v. administration of a nitric oxide (NO) synthase inhibitor, L-NG-nitroarginine (L-NOArg), on the increase in cerebral cortical blood flow (cortical BF), following either electrical stimulation of the nucleus basalis of Meynert (NBM), whose cholinergic fibers project to the cortex, or hypercapnia with...

journal_title：Neuroscience letters

authors： Adachi T,Inanami O,Sato A

更新日期：1992-05-25 00:00:00

abstract：:The spinal nucleus of the bulbocavernosus (SNB) in rodents is a neuromuscular system consisting of lumbar motoneurons and the perineal muscles they innervate, the bulbocavernosus and levator ani. This system is present prenatally in both males and females but degenerates postnatally in females because of the lack of p...

journal_title：Neuroscience letters

authors： Smith MR,Hamson DK,Poort JE,Jordan CL,Breedlove SM

更新日期：2012-04-04 00:00:00

abstract：:Neuropeptides, synthesized in dorsal root ganglia (DRG), are implicated in nociception and neurogenic inflammation. Alterations in DRG neuropeptide levels have been described in polyarthritic rats, but these models are associated with widespread systemic disease. Using mild adjuvant-mediated monoarthritis of the left ...

journal_title：Neuroscience letters

authors： Smith GD,Harmar AJ,McQueen DS,Seckl JR

更新日期：1992-03-30 00:00:00

abstract：:Elevated introcular pressure (IOP)-induced retinal neuron ischemic death includes an early phase of necrosis and prolonged phase of apoptosis. We used this ischemic model to observe the changes of sortilin and p75(NTR) protein expressions in rat retina. The results of Western blot analysis showed the expression of p75...

journal_title：Neuroscience letters

authors： Wei Y,Wang N,Lu Q,Zhang N,Zheng D,Li J

更新日期：2007-12-18 00:00:00

abstract：:Inflammation is an important contributor to the development of Alzheimer's disease (AD). Anti-inflammatory medication may offer promising treatment for AD. Hydroxy-safflor yellow A (HSYA), a chemical component of the safflower yellow pigments, has been reported to exert potent immunosuppressive effects. This study exa...

journal_title：Neuroscience letters

authors： Zhang Z,Wu Z,Zhu X,Hui X,Pan J,Xu Y

更新日期：2014-03-06 00:00:00

abstract：:Synaptic plasticity in olfactory inputs to the lateral entorhinal cortex may result in lasting changes in the processing of olfactory stimuli. Changes in dopaminergic tone can have strong effects on basal evoked synaptic responses in the superficial layers of the entorhinal cortex, and the current study investigated w...

journal_title：Neuroscience letters

authors： Caruana DA,Reed SJ,Sliz DJ,Chapman CA

更新日期：2007-10-09 00:00:00

abstract：:Using immunohistochemical techniques, we demonstrate aspartate aminotransferase (AAT)-like immunoreactivity in cone pedicles and ganglion cells of the cat retina. An identical pattern was seen when we stained for cytochrome oxidase activity, a marker for neurons which have a high metabolic activity. Tetrodotoxin selec...

journal_title：Neuroscience letters

authors： Bolz J,Thier P,Brecha N

更新日期：1985-02-04 00:00:00

abstract：:Fibroblasts from Alzheimer's disease (AD) patients displayed decreased cytochrome c oxidase (complex IV) activity (P < 0.05). The basal oxygen consumption rate (QO2) and the response to an uncoupler of oxidative phosphorylation did not differ between AD and control fibroblasts. The QO2 of AD fibroblasts was more susce...

journal_title：Neuroscience letters

authors： Curti D,Rognoni F,Gasparini L,Cattaneo A,Paolillo M,Racchi M,Zani L,Bianchetti A,Trabucchi M,Bergamaschi S,Govoni S

更新日期：1997-10-24 00:00:00

abstract：:Recently a full genome survey detected an allelic association between Alzheimer's disease (AD) and the D10S1423 marker on chromosome 10p12-14 (40 cM from the telomere). In this study we examined the D10S1423 marker in an ethnically homogeneous German population of 80 AD patients and two groups of controls, 168 healthy...

journal_title：Neuroscience letters

authors： Majores M,Bagli M,Papassotiropoulos A,Schwab SG,Jessen F,Rao ML,Maier W,Heun R

更新日期：2000-08-11 00:00:00

abstract：:Local cerebral glucose utilization (LCGU) was measured during spontaneous waking and slow wave sleep (SWS) by an adaptation of the [14C]deoxyglucose method to the free moving cat. In awake animals heterogeneous rates of LCGU were observed throughout the brain with values extending from 8 mumol x 100 g-1 x min-1 for wh...

journal_title：Neuroscience letters

authors： Petitjean F,Seguin S,Des Rosiers MH,Salvert D,Buda C,Janin M,Debilly G,Jouvet M,Bobillier P

更新日期：1982-09-20 00:00:00

abstract：:HS-142-1 is a novel non-peptide antagonist for atrial natriuretic peptide (ANP) receptor. The effect of HS-142-1 on the cyclic GMP production elicited by natriuretic peptides in neuronal cell lines, PC12 and NG108-15 was examined. Natriuretic peptides such as ANP, brain natriuretic peptide (BNP), and C-type natriureti...

journal_title：Neuroscience letters

authors： Toki S,Morishita Y,Sano T,Matsuda Y

更新日期：1992-01-20 00:00:00

abstract：:The effect of preconditioning (PC) on the changes of nerve growth factor-induced gene A (NGFI-A) expression induced by severe hypobaric hypoxia was studied by in situ hybridization. A PC consisted of three trials of mild hypobaric hypoxia (360 Torr, 2 h) spaced at 24 h. The last trial was followed by severe hypoxia (S...

journal_title：Neuroscience letters

authors： Rybnikova E,Tulkova E,Pelto-Huikko M,Samoilov M

更新日期：2002-08-23 00:00:00

abstract：:Incorporation of ubiquitin and ubiquitin-related proteins including p62 into neuronal intranuclear inclusions (NIIs) has been reported in a variety of neurodegenerative diseases. However, involvement of autophagy-specific proteins (NBR1 and LC3) in NIIs has not been mentioned. We immunohistochemically examined the bra...

journal_title：Neuroscience letters

authors： Mori F,Tanji K,Odagiri S,Toyoshima Y,Yoshida M,Kakita A,Takahashi H,Wakabayashi K

更新日期：2012-08-01 00:00:00

abstract：:Segments of the mouse sciatic nerve were preloaded with either d-2,3-(3)H-Aspartic acid [nonmetabolizable analog of glutamate] or l-(14)C-proline and the release of these exogenous molecules was evaluated in the fractions of the perfusate following electrical or magnetic stimulation. The electrical stimulation (10Hz, ...

journal_title：Neuroscience letters

authors： Wieraszko A,Ahmed Z

更新日期：2009-07-10 00:00:00

abstract：:Bereitschaftspotentials (BPs) preceding muscle relaxation and contraction were compared by using subdural electrodes which were implanted onto the right medial frontal surface in two patients with supplementary motor area (SMA) seizure. The applied movement paradigm (muscle relaxation and contraction tasks) was comple...

journal_title：Neuroscience letters

authors： Yazawa S,Ikeda A,Kunieda T,Mima T,Nagamine T,Ohara S,Terada K,Taki W,Kimura J,Shibasaki H

更新日期：1998-03-20 00:00:00

abstract：:In chick brain microvessels, monoamine oxidase activity using catecholamines (dopamine and noradrenaline) and indoleamines (serotonin and tryptamine) as substrates was higher than that measured in synaptosomes and free mitochondria. In contrast, phenylalkyamines such as tyramine and 2-phenylethylamine were more deamin...

journal_title：Neuroscience letters

authors： Durand M

更新日期：1986-12-12 00:00:00

abstract：:Cerebrospinal fluid (CSF) was obtained from donor rats either during the dark or during the light period of their diurnal cycle, and infused into the lateral ventricle of recipient rats. Infusing recipient rats during their dark period with CSF from light-exposed donors reduced the motor activity, whereas, conversely,...

journal_title：Neuroscience letters

authors： Sachs J,Ungar J,Waser PG,Borbély AA

更新日期：1976-04-01 00:00:00

abstract：:Eukaryotic mRNA precursors are co-transcriptionally assembled into ribonucleoprotein complexes. Heterogeneous nuclear ribonucleoprotein (hnRNP) complexes are involved in mRNA translocation, stability, subcellular localization and regulation of mRNA translation. About 20 major classes of hnRNPs have been identified in ...

journal_title：Neuroscience letters

authors： Lopes GS,Lico DTP,Silva-Rocha R,de Oliveira RR,Sebollela A,Paçó-Larson ML,Larson RE

更新日期：2019-03-23 00:00:00

abstract：:We have previously demonstrated that repeated exposure of adult rat hippocampal slices to brief episodes of hypoxia induce a sustained decrease in the threshold of stimulus-evoked population spike discharges in CA1 pyramidal neurons [O. Godukhin, A. Savin, S. Kalemenev, S. Levin, Neuronal hyperexcitability induced by ...

journal_title：Neuroscience letters

authors： Levin S,Godukhin O

更新日期：2005-03-22 00:00:00

abstract：:Although aging-related alterations in the auditory sensory memory and involuntary change discrimination have been widely studied, it remains controversial whether the mismatch negativity (MMN) or its magnetic counterpart (MMNm) is modulated by physiological aging. This study aimed to examine the effects of aging on mi...

journal_title：Neuroscience letters

authors： Cheng CH,Baillet S,Hsiao FJ,Lin YY

更新日期：2013-06-07 00:00:00

abstract：:The effects of glutamate uptake inhibitors on the L-glutamate-induced increase in intracellular calcium concentrations were assessed in rat primary cortical cultures. The glutamate (10 microM)-induced rise in intracellular calcium concentrations was strongly and dose dependently increased and prolonged by simultaneous...

journal_title：Neuroscience letters

authors： Freund WD,Grieshop B,Neumann U,Reddig S

更新日期：1995-03-16 00:00:00