Allocentrically implied target locations are updated in an eye-centred reference frame.

abstract：:The effects of glutamate uptake inhibitors on the L-glutamate-induced increase in intracellular calcium concentrations were assessed in rat primary cortical cultures. The glutamate (10 microM)-induced rise in intracellular calcium concentrations was strongly and dose dependently increased and prolonged by simultaneous...

journal_title：Neuroscience letters

authors： Freund WD,Grieshop B,Neumann U,Reddig S

更新日期：1995-03-16 00:00:00

abstract：:The brains of 7 dogs aged 6 to 18 years have been histochemically and immunohistochemically investigated at the light- and electron microscopy levels for preamyloid deposits and amyloid fibrils to verify the hypothesis that the accumulation of cleavage products of amyloid precursor protein is related not only to Alzhe...

journal_title：Neuroscience letters

authors： Giaccone G,Verga L,Finazzi M,Pollo B,Tagliavini F,Frangione B,Bugiani O

更新日期：1990-07-03 00:00:00

abstract：:People with Down syndrome develop Alzheimer's disease with an early age of onset. Plasma amyloid beta (Abeta) levels were measured in individuals with Down syndrome who were over the age of 40. No associations between age and Abeta1-40 and Abeta1-42 concentrations were found and nor were Abeta1-40 and Abeta1-42 levels...

journal_title：Neuroscience letters

authors： Jones EL,Hanney M,Francis PT,Ballard CG

更新日期：2009-02-20 00:00:00

abstract：:Deep brain stimulation (DBS) is now emerging as a new option for treating intractable epilepsy. Cumulative studies suggest that the mediodorsal thalamic nucleus (MD) is involved in limbic seizure activity. This study aims to investigate whether DBS of the MD can protect against seizures induced by amygdaloid kindling....

journal_title：Neuroscience letters

authors： Wang S,Wu DC,Fan XN,Zhu MZ,Hu QY,Zhou D,Ding MP,Chen Z

更新日期：2010-09-06 00:00:00

abstract：:The goal of this study was to examine the coupling between visual information and body sway with binocular and monocular vision at two distances from the front wall of a moving room. Ten participants stood as still as possible inside of a moving room facing the front wall in conditions that combined room movement with...

journal_title：Neuroscience letters

authors： Moraes R,Lopes AG,Barela JA

更新日期：2009-09-04 00:00:00

abstract：:Seizures are relatively common in the first weeks of life and can have lasting effects on brain development due to glutamate excitotoxicity. The excitatory amino acid transporter 2 (EAAT2) is responsible for the majority of glutamate uptake in the brain and mice with this gene deleted die from seizures. Therefore, we ...

journal_title：Neuroscience letters

authors： Lauriat TL,Schmeidler J,McInnes LA

更新日期：2007-01-22 00:00:00

abstract：OBJECT:Much evidence has demonstrated that stress and tumor interact, but the mechanisms are poorly understood. The purpose of this study is to discuss the effect of unpredictable chronic mild stress (CMS) upon the behavior of Walker 256 tumor-bearing rats and its mechanism. METHODS:Observe the effects of CMS on the s...

journal_title：Neuroscience letters

authors： Xiu LJ,Lin HM,Wei PK

更新日期：2010-03-31 00:00:00

abstract：:We evaluated long-term dynorphin A-immunoreactivity in the rat area postrema (AP) after the administration of cisplatin. First, rats were given 1, 5 and 10mg/kg body weight cisplatin (i.p.) and their behavior was monitored for 72h. We observed a delayed increase in pica 24-72h after injection, compared to the 24h befo...

journal_title：Neuroscience letters

authors： Tsukamoto G,Ichikawa H,Kobashi M,Yamada Y,Kikuchi T,Mese H,Sasaki A

更新日期：2007-09-07 00:00:00

abstract：:Phencyclidine (PCP) is known to be an inhibitor of serotonin (5-HT) uptake and to increase serotonergic activity. The development of tolerance to serotonergic stereotyped behaviors induced by repeated PCP treatment and changes of 5-HT transporters were examined. Backpedalling was significantly reduced in frequency fol...

journal_title：Neuroscience letters

authors： Hori T,Abe S,Baba A,Suzuki T,Shiraishi H

更新日期：2000-02-11 00:00:00

abstract：:Physical exercise-induced inflammation may be beneficial when exercise is regular but it may be harmful when exercise is intense and performed by unaccustomed individuals/rats. Molecular hydrogen (H2) has recently emerged as a powerful anti-inflammatory, antioxidant and anti-apoptotic molecule in a number of pathologi...

journal_title：Neuroscience letters

authors： Nogueira JE,de Deus JL,Amorim MR,Batalhão ME,Leão RM,Carnio EC,Branco LGS

更新日期：2020-01-10 00:00:00

abstract：:Although aging-related alterations in the auditory sensory memory and involuntary change discrimination have been widely studied, it remains controversial whether the mismatch negativity (MMN) or its magnetic counterpart (MMNm) is modulated by physiological aging. This study aimed to examine the effects of aging on mi...

journal_title：Neuroscience letters

authors： Cheng CH,Baillet S,Hsiao FJ,Lin YY

更新日期：2013-06-07 00:00:00

abstract：:We immunohistochemically investigated the degeneration processes of the nigro-striatal and nigro-amygdaloid pathways and the relationship between the loss of dopaminergic neurons and Lewy bodies (LB) formation in the substantia nigra using 15 autopsied cases of dementia with Lewy bodies (DLB). The number of tyrosine h...

journal_title：Neuroscience letters

authors： Iseki E,Marui W,Yamamoto R,Togo T,Katsuse O,Kato M,Iwatsubo T,Kosaka K,Arai H

更新日期：2005-05-20 00:00:00

abstract：:Tau is a neuronal microtubule-associated protein found predominantly in axons. Hyperphosphorylation of tau reduces the stability of microtubules, which may be a pathogenic mechanism in Alzheimer's disease. To understand the different effects between tau and glycogen synthase kinase 3beta (GSK-3beta) phosphorylated tau...

journal_title：Neuroscience letters

authors： Sang H,Lu Z,Li Y,Ru B,Wang W,Chen J

更新日期：2001-10-26 00:00:00

abstract：:Tyrosine phosphorylation is an important means for regulating post-ischemic signal transduction. In this article, brain ischemia was induced by four-vessel occlusion, and the effect of ischemia/reperfusion on proline-rich tyrosine kinase 2 (Pyk2) was studied. Tyrosine phosphorylation of Pyk2 in Sprague-Dawley rat hipp...

journal_title：Neuroscience letters

authors： Liu Y,Zhang GY,Hou XY,Xu TL

更新日期：2003-09-18 00:00:00

abstract：:P2X7 receptor is a ligand gated ion channel found peripheral macrophages and microglia in the nervous system. The current study investigated the relationship between the activated P2X7 and depression for the first time. Chrysophanol (Chr) was examined for its protective effects against depression targeting P2X7. Chr (...

journal_title：Neuroscience letters

authors： Zhang K,Liu J,You X,Kong P,Song Y,Cao L,Yang S,Wang W,Fu Q,Ma Z

更新日期：2016-02-02 00:00:00

abstract：:Substance P (SP) stimulates striatal dopamine outflow through a cholinergic muscarinic link. SP-induced increase in acetylcholine (Ach) is concentration-dependent, whereas the stimulation of dopamine outflow is seen only over a limited concentration range. M(1) and M(2) receptor stimulation has opposite effects on dop...

journal_title：Neuroscience letters

authors： Khan S,Whelpton R,Michael-Titus AT

更新日期：2000-11-03 00:00:00

abstract：:The contribution of angiotensin II (Ang II) to the pathophysiology of hypertension is established based on facts that high levels of circulating Ang II increase vasoconstriction of peripheral arteries causing a rise in blood pressure (BP). In addition, circulating Ang II has various effects on the central nervous syst...

journal_title：Neuroscience letters

authors： Issa AT,Miyata K,Heng V,Mitchell KD,Derbenev AV

更新日期：2012-06-21 00:00:00

abstract：:Recent studies have suggested the involvement of some metabolic hormones in memory formation and synaptic plasticity. Insulin dysfunction is known as an essential process in the pathogenesis of sporadic Alzheimer's disease (AD). In this study we examined whether adiponectin (ADN), as an insulin-sensitizing adipokine, ...

journal_title：Neuroscience letters

authors： Pousti F,Ahmadi R,Mirahmadi F,Hosseinmardi N,Rohampour K

更新日期：2018-01-01 00:00:00

abstract：:Melatonin protection against H2O2-induced lipid peroxidation in brain homogenates was measured in vitro. The level of malonaldehyde (MDA) plus 4-hydroxyalkenals (4-HDA) was assayed in brain homogenates as an index of induced membrane oxidative damage. Brain homogenates were co-incubated with H2O2 alone or in combinati...

journal_title：Neuroscience letters

authors： Sewerynek E,Poeggeler B,Melchiorri D,Reiter RJ

更新日期：1995-08-11 00:00:00

abstract：:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain t...

journal_title：Neuroscience letters

authors： Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

更新日期：2008-08-08 00:00:00

abstract：:In this review, we summarize the recent development of positron emission tomography (PET) radioligands for γ-aminobutyric acid A (GABAA) receptors and their potential to measure changes in endogenous GABA levels and highlight the clinical and translational applications of GABA-sensitive PET radioligands. We review the...

journal_title：Neuroscience letters

authors： Andersson JD,Matuskey D,Finnema SJ

更新日期：2019-01-19 00:00:00

abstract：:Apoptosis is thought to play a role in neuronal pathology in schizophrenia. Recently, the GSN gene was reported to have anti-apoptotic properties. In a genome-wide expression analysis on schizophrenia, GSN was also found to be significantly down-regulated in schizophrenia. All the hints suggest that GSN is a novel can...

journal_title：Neuroscience letters

authors： Xi ZR,Qin W,Yang YF,He G,Gao SH,Ren MS,Peng YW,Zhang Z,He L

更新日期：2004-12-06 00:00:00

abstract：:Genetic polymorphism of human bleomycin hydrolase (hBH) has been reported to be associated with the risk of sporadic Alzheimer's disease (AD). The regional and cellular distribution of mRNA encoding hBH in the brain from controls and patients with AD was examined using in situ hybridization. A hybridization signal, in...

journal_title：Neuroscience letters

authors： Malherbe P,Faull RL,Richards JG

更新日期：2000-03-03 00:00:00

abstract：:The myelin oligodendrocyte glycoprotein (MOG) is a minor CNS myelin-specific protein that is an important candidate autoantigen in multiple sclerosis. We now report that MOG mRNA transcripts are present in the peripheral nervous system of rodents and primates at levels approximately ten-fold lower than in brain as dem...

journal_title：Neuroscience letters

authors： Pagany M,Jagodic M,Schubart A,Pham-Dinh D,Bachelin C,Baron van Evercooren A,Lachapelle F,Olsson T,Linington C

更新日期：2003-10-30 00:00:00

abstract：:Occasional repetitions embedded in a sequence of ever-changing sounds elicit a frontally negative event-related potential peaking between 100 and 200 ms from the onset of sound repetition (repetition negativity, RN). Three interpretations have been suggested for the emergence of RN: (1) RN is a mismatch negativity (MM...

journal_title：Neuroscience letters

authors： Horváth J,Winkler I

更新日期：2004-09-23 00:00:00

abstract：:For the first time, a review article focuses exclusively on the role of the protein kinase CK2 in mono- and poly-nucleated mammalian skeletal muscle cells. While CK2, a pleiotropic serine/threonine kinase was originally thought to phosphorylate mainly casein, later evidence found glycogen phosphorylase and glycogen sy...

journal_title：Neuroscience letters

authors： Hashemolhosseini S

更新日期：2020-06-11 00:00:00

abstract：:Among the techniques used to reduce spatial neglect's symptoms, left neck muscle vibration (NMV) is alluring because it does not require the patient's attentional co-operation. The aim of this study was to determine the type of NMV-associated feedback that induced the most intense and longest-lasting egocentric post-e...

journal_title：Neuroscience letters

authors： Ceyte H,Beis JM,Ceyte G,Caudron S

更新日期：2021-01-19 00:00:00

abstract：:In the present study, we tried to examine whether the 2-deoxy-D-[14C]glucose (2-DG) technique is useful to investigate the metabolic activity of fetal rat brain in the maternal uterus. The result shows that metabolic mapping of the fetal brain was clearly obtained by means of the 2-DG technique. ...

journal_title：Neuroscience letters

authors： Morimoto A,Imai-Matsumura K,Murakami N

更新日期：1990-03-26 00:00:00

abstract：:Dysregulated brain glucose metabolism and lactate accumulation are seen following traumatic brain injury (TBI). The underlying molecular mechanism is poorly understood. Pyruvate dehydrogenase (PDH), the rate-limiting enzyme coupling cytosolic glycolysis to mitochondrial citric acid cycle, plays a critical role in main...

journal_title：Neuroscience letters

authors： Xing G,Ren M,Watson WD,O'Neill JT,Verma A

更新日期：2009-04-17 00:00:00

abstract：:In this study, we aimed to investigate whether self-reported mild traumatic brain injury (mTBI) was associated with decreased AD-vulnerable cortical thickness, and to assess the relationship between AD-vulnerable cortical thickness and AD-related biomarker in the Alzheimer's Disease Neuroimaging Initiative subjects. W...

journal_title：Neuroscience letters

authors： Wang ML,Wei XE,Yu MM,Li PY,Li WB,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2017-08-10 00:00:00