Mediodorsal thalamic stimulation is not protective against seizures induced by amygdaloid kindling in rats.

abstract：:The effect of 4-aminopyridine (4-AP) on long-term potentiation (LTP) was studied in the hippocampal slice preparation of the rat. Field excitatory postsynaptic potentials (EPSPs) were recorded and evoked in the stratum radiatum of the CA1. Both the low frequency EPSP and LTP of the EPSP were significantly increased by...

journal_title：Neuroscience letters

authors： Lee WL,Anwyl R,Rowan M

更新日期：1986-09-25 00:00:00

abstract：:c-Fos is one of the transcription factors contributing to the regulation of the downstream gene expression. Administration of dopamine D1 receptor agonist or D2 receptor antagonist have been known to induce c-Fos expressions in striatal projection neurons. We examined the effects of unilateral ablation of the globus p...

journal_title：Neuroscience letters

authors： Miwa H,Fuwa T,Nishi K,Mizuno Y

更新日期：1998-01-16 00:00:00

abstract：:Brain content of leucine-enkephalin and methionine-enkephalin changes independently during kindling of the amygdala. Both peptides were measured after 4, 8, 15 and 21 days of stimulation. Leu-enkephalin showed a progressive increase during the kindling: the results on the 4th day did not differ significantly from the ...

journal_title：Neuroscience letters

authors： Vindrola O,Briones R,Asai M,Fernández-Guardiola A

更新日期：1981-10-23 00:00:00

abstract：:Mutations in DJ-1 cause familial Parkinson's disease (PD). The expression pattern of DJ-1 in the brain remains controversial. In the present study, we used DJ-1 deficient mice as negative controls and examined DJ-1 mRNA expression in mouse brains. In sequential double labeling on the same sections, in situ hybridizati...

journal_title：Neuroscience letters

authors： Xie Z,Zhuang X,Chen L

更新日期：2009-11-20 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by the presence of beta-amyloid (Abeta) protein deposits in the brain and increased Abeta (1-42) peptide production is thought to be one of the early events in the pathogenesis of AD that leads to progressive neurodegenerative processes and dementia. Using cDNA subtraction and...

journal_title：Neuroscience letters

authors： Heese K,Nagai Y,Sawada T

更新日期：2000-07-07 00:00:00

abstract：:The antigenic components of Lewy bodies in the cerebral cortex and substantia nigra in 5 cases of diffuse Lewy body disease were examined by immunocytochemistry, using antibodies to neurofilaments (in the phosphorylated or non-phosphorylated forms); to ubiquitin; to the microtubule-associated proteins MAP1, MAP2 and t...

journal_title：Neuroscience letters

authors： Galloway PG,Bergeron C,Perry G

更新日期：1989-05-22 00:00:00

abstract：:Tumor cells frequently express the insulin-like growth factor I (IGF-I). Recently we demonstrated that rat glioma cells when transfected with a vector encoding antisense IGF-I cDNA lost tumorigenicity and induced a tumor specific immune response involving CD8+ lymphocytes. Here we show that the cultured transfected ce...

journal_title：Neuroscience letters

authors： Trojan J,Duc HT,Upegui-Gonzalez LC,Hor F,Guo Y,Anthony D,Ilan J

更新日期：1996-07-05 00:00:00

abstract：:Dopaminergic neurons of the goldfish retina were selectively destroyed after a single intravitreal injection of 1-methyl-4-phenylpyridinium ion (MPP+). The ultrastructural analysis of the retina 3 days after toxin administration shows darkening of some retinal neurons present in the inner nuclear layer including their...

journal_title：Neuroscience letters

authors： Villani L,Poli A,Bissoli R,Barnabei O

更新日期：1988-03-31 00:00:00

abstract：:The localization of luteinizing hormone-releasing hormone (LH-RH) has been studied in the human brain with the indirect immunofluorescence technique. LH-RH positive perikarya are scattered from the septo-preoptic region up to the retromammillary area and give rise to two main tracts ending in the infundibulum and the ...

journal_title：Neuroscience letters

authors： Barry J

更新日期：1976-12-01 00:00:00

abstract：:Prevention of beta-amyloid (Abeta) production, aggregation and formation of Abeta deposits is a key pharmacological target in Alzheimer's disease. The passage of Abeta-binding compounds through the blood-brain barrier is often hampered for free ligands, whereas it is enhanced by drug encapsulation in nanoparticles. He...

journal_title：Neuroscience letters

authors： Härtig W,Paulke BR,Varga C,Seeger J,Harkany T,Kacza J

更新日期：2003-02-27 00:00:00

abstract：:We studied event-related desynchronization (ERD) of the 8-13 Hz rhythm (mu rhythm) of the primary somatosensory cortex (SI) caused by contra- and ipsilateral median-nerve stimulation. We used whole-head magnetoencephalography (MEG) and wavelet analysis together with our newly developed color-coded single-trial ERD dis...

journal_title：Neuroscience letters

authors： Nikouline VV,Linkenkaer-Hansen K,Wikström H,Kesäniemi M,Antonova EV,Ilmoniemi RJ,Huttunen J

更新日期：2000-11-24 00:00:00

abstract：:To investigate whether there is a descending contribution to the spinal 5-hydroxytryptamine (5-HT) innervation in the lamprey, a primitive vertebrate, a study using retrograde transport of the fluorescent tracer Fast blue combined with 5-HT immunohistochemistry was conducted. Two to 4 weeks after an injection of Fast ...

journal_title：Neuroscience letters

authors： Brodin L,Buchanan JT,Hökfelt T,Grillner S,Verhofstad AA

更新日期：1986-06-06 00:00:00

abstract：:The subcommissural organ (SCO) is a glandular circumventricular organ secreting glycoproteins into the cerebrospinal fluid. The SCO of 15-week-old spontaneously hypertensive rats (SHR) and of matched normotensive Wistar-Kyoto rats (WKY) was studied immunocytochemically by using an antibody against the glycoproteins se...

journal_title：Neuroscience letters

authors： Castañeyra-Perdomo A,Carmona-Calero E,Meyer G,Pérez-González H,Pérez-Delgado MM,Marrero-Gordillo N,Rodríguez S,Rodríguez EM

更新日期：1998-05-01 00:00:00

abstract：:In this work, we attempt to extend to the schizophrenia's research the evidence that different frequency bands may emerge from different sources during early-stage visual processing, in a mental state-specific manner, while subjects are passively viewing a visual stimulus. We applied standard pattern reversal stimulat...

journal_title：Neuroscience letters

authors： González-Hernández JA,Pita-Alcorta C,Castañeda H,Trujillo-Barreto N,Scherbaum WA

更新日期：2009-01-23 00:00:00

abstract：:Neuronal apoptosis sculpts the developing brain, and nearly all identified classes of neurons seem to be produced "in excess" during development. FoxO transcription factors regulate apoptosis in vitro in deprived of neurotrophins. It is unknown if FoxO3a is involved in the development of neurons. Here, we report a rol...

journal_title：Neuroscience letters

authors： Peng K,Li Y,Long L,Li D,Jia Q,Wang Y,Shen Q,Tang Y,Wen L,Kung HF,Peng Y

更新日期：2010-10-29 00:00:00

abstract：:A major goal in the study of motor learning is to improve the extent to which subjects adapt their movements in response to errors. Recent attention has focused on the gradual-adaptation paradigm, in which an adaptive stimulus is introduced incrementally, rather than all at once as in conventional adaptation paradigms...

journal_title：Neuroscience letters

authors： Wong AL,Shelhamer M

更新日期：2011-08-18 00:00:00

abstract：:The human basal forebrain has been known to contain many neurons immunoreactive (ir) to tyrosine hydroxylase (TH; the first dopamine-synthesizing enzyme). We examined whether these neurons might contain aromatic L-amino acid decarboxylase (AADC; the second step dopamine-synthesizing enzyme) by dual labeling immunohist...

journal_title：Neuroscience letters

authors： Ikemoto K,Nagatsu I,Kitahama K,Jouvet A,Nishimura A,Nishi K,Maeda T,Arai R

更新日期：1998-02-27 00:00:00

abstract：:An analysis was made of primary afferent and dorsal horn neuron responses to stimulation of genitalia of female cats. Three types of primary afferents responded to vaginal probing. The most common type responded maximally to the on- and off-ramps of non-noxious pressure applied directly to the clitoris. A second type ...

journal_title：Neuroscience letters

authors： Price DD,Bushnell MC,Iadarola MJ

更新日期：1981-10-01 00:00:00

abstract：:The mechanisms responsible for the termination of paroxysmal depolarization shifts (PDS) were studied with intracellular recordings on CA1 neurons of rat hippocampal slices. Epileptiform activity was induced by application of penicillin, bicuculline or Mg-free artificial cerebrospinal fluid (ACSF). PDS in penicillin-c...

journal_title：Neuroscience letters

authors： Domann R,Westerhoff CH,Witte OW

更新日期：1994-07-18 00:00:00

abstract：:The effects of several Ca2+ channel blockers were evaluated on inhibitory junction potential (IJP) evoked in rat colonic circular muscle by electrical field stimulation (EFS). Glass microelecrodes were used to record membrane potential of smooth muscle cells. IJPs were tetrodotoxin-sensitive (1 microM) and disappeared...

journal_title：Neuroscience letters

authors： Borderies JR,Jiménez M,Angel F

更新日期：1996-05-31 00:00:00

abstract：:Repeated exposure to dizocilpine (MK-801) can be used as a model of schizophrenia that incorporates disease progression. Proton magnetic resonance spectroscopy (1H MRS) has been widely used to investigate schizophrenia-related alterations in glutamate (Glu). The purpose of this study was to investigate metabolic alter...

journal_title：Neuroscience letters

authors： Yoo CH,Song KH,Lim SI,Lee DW,Woo DC,Choe BY

更新日期：2017-01-10 00:00:00

abstract：:Freshwater clams are a popular health food in Asia and are traditionally used to prevent hepatic inflammation. Freshwater clam extract (FCE) inhibits inflammatory responses in activated macrophages by reducing the activation of mitogen-activated protein kinase and nuclear factor kappa-light-chain-enhancer of activated...

journal_title：Neuroscience letters

authors： Hsieh CC,Lin MS,Hua KF,Chen WJ,Lin CC

更新日期：2017-03-06 00:00:00

abstract：:Focal ischemia was induced in the fronto-parietal region of rat brain, by injection of Rose Bengal, followed by light activation. Focal ischemia was accompanied by formation of PGD(2) peaking 60-90 min post irradiation and declining thereafter. Increased Cycloxygenase-2 (COX-2) expression was also observed. Control is...

journal_title：Neuroscience letters

authors： Govoni S,Masoero E,Favalli L,Rozza A,Scelsi R,Viappiani S,Buccellati C,Sala A,Folco G

更新日期：2001-05-04 00:00:00

abstract：:Rapid eye movement (REM) is one of the most characteristic features of REM sleep, but the mechanisms underlying its regulation remain unclear. The present study aims to investigate whether the frontal eye field (FEF) is involved in the regulation of the rapid eye movements during REM sleep. To address this question, w...

journal_title：Neuroscience letters

authors： Yu S,Liu N,Zeng T,Tian S,Chen N,Zhou Y,Ma Y

更新日期：2004-08-05 00:00:00

abstract：:To assess the neurotoxic properties of the glutamate agonist quisqualic acid (QA) in immature brain, we injected this compound (100 nmol QA/1 microliter) directly into the striatum of 7-day-old rats. QA produced neuronal necrosis and glial infiltration in 14 pups and reduced the size of the striatum and hippocampus on...

journal_title：Neuroscience letters

authors： Silverstein FS,Chen R,Johnston MV

更新日期：1986-10-30 00:00:00

abstract：:In the rat, unilateral dorsal cervicothoracic rhizotomy (C5-T2) resulted in autotomy of the ipsilateral limb. The onset of self-mutilation was variable and attained the maximum degree 8-9 weeks after the dorsal root section. Fifteen and 60 days after the lesion the monoamines dopamine (DA), noradrenaline (NA) and sero...

journal_title：Neuroscience letters

authors： Colado MI,Arnedo A,Peralta E,Del Río J

更新日期：1988-05-03 00:00:00

abstract：:The parietal cortex of the human brain plays a unique role in the coordination of movement and in the integration of signals from the other cortices. Because of its extensive connections and involvement in many higher-order cognitive functions, neurodegenerative changes in the parietal lobe are believed to be crucial ...

journal_title：Neuroscience letters

authors： Mills JD,Nalpathamkalam T,Jacobs HI,Janitz C,Merico D,Hu P,Janitz M

更新日期：2013-03-01 00:00:00

abstract：:Normal treatment of rats with monosodium-L-glutamate (MSG) resulted in extensive degeneration of the inner nuclear layer of the retina. The retino-hypothalamic projection was still functional as these rats entrained their circadian food intake rhythm to the light-dark cycle. A normal proportion of dorsal lateral genic...

journal_title：Neuroscience letters

authors： Groos G

更新日期：1981-09-25 00:00:00

abstract：:Serotonin-immunoreactive (5HT-IR) neurons were investigated in the brain and rostral (cervical) spinal cord of the garfish, a non-teleost actinopterygian. The diencephalon contained a prominent 5HT-IR cell group consisting mainly of liquor-contacting neurons in the hypothalamic periventricular wall. Their ependymofuga...

journal_title：Neuroscience letters

authors： Chiba A,Oka S

更新日期：1999-02-12 00:00:00

abstract：:To examine whether the Haken-Kelso-Bunz model for rhythmic interlimb coordination applies to walking side-by-side on a treadmill, we invited six pairs of participants to coordinate their stepping movements at seven prescribed relative phases (between 0 degrees and 180 degrees ) to scan the attractor layout governing t...

journal_title：Neuroscience letters

authors： van Ulzen NR,Lamoth CJ,Daffertshofer A,Semin GR,Beek PJ

更新日期：2010-04-26 00:00:00