Abstract:
:Rapid eye movement (REM) is one of the most characteristic features of REM sleep, but the mechanisms underlying its regulation remain unclear. The present study aims to investigate whether the frontal eye field (FEF) is involved in the regulation of the rapid eye movements during REM sleep. To address this question, we ablated the FEF in four rhesus monkeys and observed the effects of the lesions on sleep architecture. After lesions, two adult monkeys did not show any lesion effect. However, in the other two adolescent monkeys, both the total duration and percentage of the rapid eye movements during REM sleep were decreased moderately. The result suggests that the relation between the FEF and the regulation of the rapid eye movements during REM sleep may be affected by age factor, also indicating that both the functions of the FEF and the mechanisms underlying the control of rapid eye movements during REM sleep might not be the same throughout the whole life span of an animal.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Yu S,Liu N,Zeng T,Tian S,Chen N,Zhou Y,Ma Ydoi
10.1016/j.neulet.2004.05.011keywords:
subject
Has Abstractpub_date
2004-08-05 00:00:00pages
58-62issue
1eissn
0304-3940issn
1872-7972pii
S0304394004005804journal_volume
366pub_type
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