Abstract:
:We studied the effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) on seizure susceptibility in rats. rTMS of 1000 pulses at 0.5 Hz led to a prolonged latency for seizure development after an intraperitoneal injection of pentylenetetrazol. The rTMS effectively prevented the development of status epilepticus of pentylenetetrazol-induced convulsions. These findings indicate that low-frequency rTMS affects the neural excitability, in the direction of anticonvulsive, and therefore, suggest the possibility of therapeutic use of rTMS in epilepsy.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Akamatsu N,Fueta Y,Endo Y,Matsunaga K,Uozumi T,Tsuji Sdoi
10.1016/s0304-3940(01)02116-4keywords:
subject
Has Abstractpub_date
2001-09-14 00:00:00pages
153-6issue
2-3eissn
0304-3940issn
1872-7972pii
S0304394001021164journal_volume
310pub_type
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