当前位置： SCI文献检索 > NEUROSCIENCE LETTERS期刊下所有文献 > Persistent c-fos expression and NADPH-d reactivity in the medulla and the lumbar spinal cord in rat with short-term peripheral anosmia.

Persistent c-fos expression and NADPH-d reactivity in the medulla and the lumbar spinal cord in rat with short-term peripheral anosmia.

Abstract：

:Here we examine hypothesis that short-term peripheral ZnSO(4)-induced anosmia can produce effects on c-fos expression within spinal cord and caudal medulla in male Wistar rats (n=4). Fos-like-immunoreactive cells revealed by avidin-biotin-peroxidase method show a significant bilateral increase in the nucleus proprius (layers 3 and 4) and medial part of layers 5 and 6. In substantia gelatinosa (layer 2(i)) and area 10 Fos-positive neurons were intermixed together with nicotin-amide adenine dineucleotide phosphate-diaphorase (NADPH-d)-reactive cells. Short-term anosmia enhanced c-fos expression in ventral horn (layers 7 and 8), ventrolateral segment and dorsal part of the spinal trigeminal nuclei. In anosmic rats varicose fibres and numerous NADPH-d-stained neurons were present in the gelatinous layer of the spinal trigeminal nucleus caudalis, and a separate population of Fos-positive cells was detected within this layer. Nucleus tractus solitaris also contained a few NADPH-d-reactive, medium sized neurons intermixed with Fos-immunoreactive cells.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Kalueff AV,Maisky VA,Pilyavskii AI,Makarchuk NE

doi

10.1016/s0304-3940(01)01623-8

keywords:

subject

Has Abstract

pub_date

2001-03-30 00:00:00

pages

131-4

issue

2

eissn

0304-3940

issn

1872-7972

pii

S0304394001016238

journal_volume

301

pub_type

杂志文章

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