Biochemically silent posttransfusion non-A, non-B hepatitis interferes with superinfection by hepatitis A virus.

Abstract:

:Superinfection of a silently non-A, non-B (NANB)-infected chimpanzee with hepatitis A virus (HAV) resulted in minimal liver enzyme elevations, lack of detectable HAV in stool, and questionable presence of HAV antigen in liver biopsy specimens obtained during the expected period of virus replication. Our findings indicate that even biochemically silent NANB hepatitis can strongly interfere with infection by at least one other hepatotrophic virus.

journal_name

Intervirology

journal_title

Intervirology

authors

Bradley DW,Krawczynski K,Humphrey CD,McCaustland KA

doi

10.1159/000149724

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

86-90

issue

2

eissn

0300-5526

issn

1423-0100

journal_volume

27

pub_type

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