Serologic comparison of hepatitis A antigen to echovirus 25 isolate CR69(076) recovered from a patient with viral hepatitis.

abstract：BACKGROUND:Although human leukocyte antigens (HLA) have been shown in association with the outcomes of hepatitis C virus (HCV) infection among different ethnic groups, such studies remain absent in China, where the HCV prevalence is higher than the global average. METHODS:In this study, 426 HCV-infected and 709 uninfe...

journal_title：Intervirology

authors： Xiong H,Huang J,Rong X,Zhang M,Huang K,Xu R,Wang M,Li C,Liao Q,Xia W,Luo G,Ye X,Lu L,Fu Y,Guo T,Nelson K

更新日期：2015-01-01 00:00:00

abstract：:In Spodoptera frugiperda (SF IPLB-21) cells productively infected with S. frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV), we observed the synthesis of infected-cell-specific polypeptides (ICSPs) using the protein synthesis inhibitor cycloheximide (CX) and the DAN synthesis inhibitor cytosine arabinoside (A...

journal_title：Intervirology

authors： Liu HS,Bilimoria SL

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:The specific effect of rna interference on the replication of porcine hemagglutinating encephalomyelitis virus (phe-cov) was explored. METHODS:Four species of small interfering RNA (siRNA), targeting different regions of the PHE-CoV spike glycoprotein and replicase polyprotein genes, were prepared by in vitr...

journal_title：Intervirology

authors： Lan Y,Lu H,Zhao K,He W,Chen K,Wang G,Song D,Gao F

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (RSV) infection in infancy and early childhood causes acute bronchiolitis and exacerbates bronchial asthma. Eosinophil infiltration may contribute to airway obstruction in RSV infection. OBJECTIVE:We hypothesized that RSV affects eosinophil function. METHODS:Eosinophil act...

journal_title：Intervirology

authors： Tachibana A,Kimura H,Kato M,Nako Y,Kozawa K,Morikawa A

更新日期：2002-01-01 00:00:00

abstract：:The effects of cyclosporin A (CsA) upon the pathogenesis of primary cytomegalovirus (CMV) infection were investigated. Hartley and strain 2 guinea pigs were inoculated subcutaneously on day 0 with 10(4) TCD50 of virulent, salivary-gland-passaged guinea pig CMV and received oral CsA (20 mg/kg/day) for 14 days. CMV-infe...

journal_title：Intervirology

authors： Bia FJ,Lucia HL,Bia MJ,Vine W,Tuttle A

更新日期：1985-01-01 00:00:00

abstract：:We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

journal_title：Intervirology

authors： Simard C,LaBoissière S,Séguin C,Trudel M

更新日期：1991-01-01 00:00:00

abstract：:Diseases induced by animal retroviruses are not considered to be good models for the human acquired immunodeficiency syndrome (AIDS) at present. The lack of an animal model for the human immunodeficiency virus (HIV) infection presents a main problem in the complete understanding of the pathogenesis of HIV-mediated dis...

journal_title：Intervirology

authors： Dormont D,Livartowski J,Chamaret S,Guetard D,Henin D,Levagueresse R,van de Moortelle PF,Larke B,Gourmelon P,Vazeux R

更新日期：1989-01-01 00:00:00

abstract：:The transcriptases of several influenza viruses were tested for pH and temperature dependence and for thermal stability. Marked differences in pH dependence and thermostability were determined. ...

journal_title：Intervirology

authors： Broucek J,Závadová H,Vonka V

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to investigate the molecular mechanism of hepatocellular carcinoma (HCC) development induced by hepatitis B virus X protein (HBx). METHODS:We previously established a H7402-X cell line that constitutively expresses HBx protein. In the present study, H7402-X gene expression profiles a...

journal_title：Intervirology

authors： Ye L,Dong N,Wang Q,Xu Z,Cai N,Wang H,Zhang X

更新日期：2008-01-01 00:00:00

abstract：:Antibodies of individuals infected with the human immunodeficiency virus type 1 (HIV-1) were used to probe the antigenicity of the HIV-1 transmembrane protein of 41 kD (gp41) by antibody-reactive peptide scanning (Pepscan). Eleven distinct sequential antibody-binding sites were defined by testing reactivity to 339 ove...

journal_title：Intervirology

authors： Goudsmit J,Meloen RH,Brasseur R

更新日期：1990-01-01 00:00:00

abstract：:Two DNA-negative temperature-sensitive mutants of human cytomegalovirus strain AD169 were shown to be deficient in induction of several prominent viral polypeptides when grown in human foreskin fibroblasts under nonpermissive conditions. The use of a monospecific polyclonal antiserum allowed recognition of a further d...

journal_title：Intervirology

authors： Radsak K,Kaiser CJ,Haustein D,Rapp F

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND/AIMS:The nucleo-cytoplasmic large DNA viruses (NCLDV) constitute an apparently monophyletic group that consists of 6 families of viruses infecting a broad variety of eukaryotes. A comprehensive genome comparison and maximum-likelihood reconstruction of NCLDV evolution reveal a set of approximately 50 conserv...

journal_title：Intervirology

authors： Koonin EV,Yutin N

更新日期：2010-01-01 00:00:00

abstract：:Prostaglandins exhibit antiviral activity against a wide variety of RNA and DNA viruses. In the present report, we describe the effect of cyclopentenone prostaglandin A(1) (PGA(1)) on Mayaro virus replication in Vero cells. Virus yield was significantly reduced at nontoxic concentrations which did not suppress DNA, RN...

journal_title：Intervirology

authors： Burlandy FM,Rebello MA

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Hepatitis C virus (HCV) infection is a public health problem and a major cause of chronic hepatitis. This virus exhibits a great genetic variability, with 8 genotypes and numerous subtypes. The aim of this study was to evaluate the fluctuations of HCV subtypes during 2 decades in Venezuela. METHODS:HCV genot...

journal_title：Intervirology

authors： Loureiro CL,Jaspe RC,Pujol FH

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cardiovirus is a genus of viruses belonging to the family Picornaviridae. Here, we used viral metagenomic techniques to detect the viral nucleic acid in the fecal samples from wild rats in Zhenjiang city in China. METHOD:Fecal samples were collected from 20 wild rats and pooled into four sample pools a...

journal_title：Intervirology

authors： Mahmood A,Shama S,Ni H,Wang H,Ling Y,Xu H,Yang S,Naseer QA,Zhang W

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin molecule of influenza virus is considered as an ideal model to study biological processes as well as the effect of glycosylation on the function of glycoproteins. OBJECTIVES:The large subunit of the influenza virus A/New Caledonia/20/99 (H1N1) hemagglutinin (HA1) was expressed in recombina...

journal_title：Intervirology

authors： Farahmand B,Khodabandeh M,Mahboudi F,Fotouhi F,Saleh M,Barkhordari F,Tabatabaian M,Nasab FP,Kheiri MT

更新日期：2012-01-01 00:00:00

abstract：:By 48 h postinfection, 40--80% of SV40-infected CV-1 cells have undergone irreversible injury as indicated by trypan blue staining. Nevertheless, at this time the lysosomes of these cells appear as discrete structures after vital staining with either acridine orange or neutral red. Lysosomes, vitally stained with neut...

journal_title：Intervirology

authors： Einck KH,Norkin LC

更新日期：1979-01-01 00:00:00

abstract：:Among patients undergoing maintenance hemodialysis, a high prevalence of hepatitis C virus (HCV) infection can be observed. In a prospective study, sera of 273 patients were examined for the presence of HCV infection by serological tests and by PCR. Thirty-five patients (12.8%) were HCV antibody positive, and in 31 of...

journal_title：Intervirology

authors： Schröter M,Feucht HH,Schäfer P,Zöllner B,Laufs R

更新日期：1997-01-01 00:00:00

abstract：:Many individuals infected with hepatitis B virus (HBV) and hepatitis C virus (HCV) are unable to clear these viruses following an acute infection and become chronically infected. There are more than 400 million HBV and HCV carriers in the world and a considerable number of these patients would eventually develop more ...

journal_title：Intervirology

authors： Akbar SM,Horiike N,Onji M,Hino O

更新日期：2001-01-01 00:00:00

abstract：:A reverse transcriptase, polymerase chain reaction (RT-PCR) procedure was used to amplify a segment of the genome of turkey coronavirus (TCV) spanning portions of the matrix and nucleocapsid (MN) protein genes (approximately 1.1 kb). The MN gene region of three epidemiologically distinct TCV strains (Minnesota, NC95, ...

journal_title：Intervirology

authors： Breslin JJ,Smith LG,Fuller FJ,Guy JS

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Transmission of many viruses occurs by direct transmission during a close contact between two hosts, or by an indirect transmission through the environment. Several and often interconnected factors, both abiotic and biotic, determine the persistence of these viruses released in the environment, which can las...

journal_title：Intervirology

authors： Labadie T,Batéjat C,Leclercq I,Manuguerra JC

更新日期：2020-01-01 00:00:00

abstract：:Interferon induction in BSC-1 cells by measles virus isolates previously found to be interferon inducing (IF+) or interferon noninducing (IF-) was studied in different cell types. Lack of induction by the IF- viruses was not due to an inhibitory factor since BSC-1 cells coinfected with IF+ and IF- stocks produced inte...

journal_title：Intervirology

authors： McKimm-Breschkin JL,Rapp F

更新日期：1981-01-01 00:00:00

abstract：:Previous reports documented the recovery of a DNA virus from a patient with posttransfusion non-A-G hepatitis and named TT virus (TTV). Although the virus was initially detected as a causative agent of hepatitis, there is doubt about its pathogenicity. The aim of this study was to clarify the relationship between TTV ...

journal_title：Intervirology

authors： Suzuki F,Chayama K,Tsubota A,Akuta N,Someya T,Kobayashi M,Suzuki Y,Saitoh S,Arase Y,Ikeda K,Kumada H

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:To express E1 glycoprotein of rubella virus (RuV) strain JR23 in yeast and develop a diagnostic assay using expressed E1 protein as coating antigen in comparison with other diagnostic assays. METHODS:cDNA of E1 open reading frame of RuV was PCR amplified using plasmid pMD18-T-E1 as template and cloned into ...

journal_title：Intervirology

authors： Wen H,Wang Z

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...

journal_title：Intervirology

authors： Zheng L,Yang Y,Guocai L,Pauza CD,Salvato MS

更新日期：2007-01-01 00:00:00

abstract：:A BHK/21 cell line persistently infected by an arenavirus is described. During four consecutive passages, 30-45% of the cells showed granular cytoplasmic antigen by indirect immunofluorescence, employing both Argentine hemorrhagic fever convalescent sera and sera from animals immunized with Junin virus. Virus isolated...

journal_title：Intervirology

authors： Carballal G,Cossio PM,Rabinovich A,Oubiña J,Arana RM

更新日期：1980-01-01 00:00:00

abstract：:The intracellular fate of 3H-labeled exogenous herpes simplex virus type 2 DNA following the exposure of recipient cells to selected DNA facilitators and the ultrastructural changes which ensued in transfected cultures were examined. In most cases, electron microscopic radioautography demonstrated that exogenous DNA r...

journal_title：Intervirology

authors： Marciano-Cabral F,Cabral GA,Taylor MM,Patterson M,Farber FE

更新日期：1981-01-01 00:00:00

abstract：:The amino acid sequences of the virion proteins of 7 definitive tobamoviruses have been compared. The results show that the proteins may be arranged unequivocally in a single dendrogram which, by analogy with similar comparisons of other sets of homologous proteins, probably reflects their phylogeny. The magnitude of ...

journal_title：Intervirology

authors： Gibbs A

更新日期：1980-01-01 00:00:00

abstract：:Human cytomegalovirus (CMV) has devised numerous means of escaping immune surveillance. The CMV genome encodes at least 4 genes involved in downregulating surface expression of HLA class I molecules. In addition, it sequesters CC chemokines, induces Fc receptors, interferes with induction of HLA class II antigens, and...

journal_title：Intervirology

authors： Michelson S

更新日期：1999-01-01 00:00:00

abstract：:There are two major requirements for potyvirus taxonomy; group-specific criteria and criteria which discriminate between distinct viruses and strains. This review discusses the relative merits in potyvirus taxonomy of molecular parameters, such as gene sequence data, nucleic acid hybridization, coat protein sequence d...

journal_title：Intervirology

authors： Ward CW,Shukla DD

更新日期：1991-01-01 00:00:00