Abstract:
:The transcriptases of several influenza viruses were tested for pH and temperature dependence and for thermal stability. Marked differences in pH dependence and thermostability were determined.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Broucek J,Závadová H,Vonka Vdoi
10.1159/000149012subject
Has Abstractpub_date
1979-01-01 00:00:00pages
58-60issue
1eissn
0300-5526issn
1423-0100journal_volume
11pub_type
杂志文章相关文献
INTERVIROLOGY文献大全abstract::The aim of the study was to determine the prevalence of drug resistance of HIV-1 in pediatric patients from Istanbul, Turkey. Genotypic drug resistance testing revealed transmission of drug resistance from mother to child in 20%. Due to rising numbers of children with HIV-1, baseline resistance testing is recommended ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000362335
更新日期:2014-01-01 00:00:00
abstract::Rauscher murine leukemia virus (RLV) infection of adult mice results in splenomegaly that is proportional to the virus titer. We have used this model to study the therapy of chronic viremia as well as chemoprophylaxis after viral exposure, both with single agents and with combination therapy. We showed that prompt ini...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150118
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:Single-nucleotide polymorphisms (SNPs) near the interleukin (IL) 28B gene encoding a type III interferon (IFN-λ) are the most important genetic predictors of treatment response to hepatitis C virus (HCV). This retrospective study was undertaken to determine any association between IL28B SNPs and the developm...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000357326
更新日期:2014-01-01 00:00:00
abstract::Serial passage of undiluted herpes simplex virus types 1 and 2 resulted in cyclic production of infectious and defective virions. Defective virus production was characterized by the appearance of a new species of viral DNA with a higher bouyant density in CsCl than standard viral DNA. Measurement of the infectivity ti...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149894
更新日期:1975-01-01 00:00:00
abstract::Acute hemorrhagic conjunctivitis (AHC) virus strains isolated in eight different areas during epidemics of AHC were tested for the reproductive capacity at 33, 37 and 39 degrees. All of the 25 strains tested grew better at 33 degrees but restrictively at 39 degrees. The degree of temperature sensitivity varied slightl...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149952
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:The specific effect of rna interference on the replication of porcine hemagglutinating encephalomyelitis virus (phe-cov) was explored. METHODS:Four species of small interfering RNA (siRNA), targeting different regions of the PHE-CoV spike glycoprotein and replicase polyprotein genes, were prepared by in vitr...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000323523
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between enteroviral infection and myocardial tissue apoptosis during the development of viral myocarditis in a murine model. METHODS:C3H/HeJ mice were inoculated with two strains of coxsackievirus B3, specifically CVB3 (cardiovirulent Nancy strain) and CVB3/0 (noncardiovirulen...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000071453
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:Pandemic viral infections as emerging infectious diseases are of a great global concern. However, for some viruses, particular strains are endemic to specific areas and can be genetically distinguished from strains in other regions. In contrast, for some other viruses, genetically similar strains can spread a...
journal_title:Intervirology
pub_type: 杂志文章,meta分析
doi:10.1159/000320967
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Characterization of the phylogeny and diversity of human respiratory syncytial virus (HRSV) genotype ON1 that occurred during its early evolution (within the first 3.5 years since the detection of the first ON1 strains). ON1 strains have a 72-nucleotide-long in-frame duplication within the second hypervariabl...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000382018
更新日期:2015-01-01 00:00:00
abstract::Five distinct antigenic sites recognized by cytotoxic T lymphocytes in H-2b mice have been identified on simian virus 40 (SV40) T antigen. Cocultivation of SV40-transformed cells with cytotoxic T lymphocyte (CTL) clones specific for epitopes I-IV results in the selection of variants which show a loss of either epitope...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150154
更新日期:1990-01-01 00:00:00
abstract::The critical point dried (CPD) whole cell technique was applied to the study of the morphogenesis and morphology of rabies virus and vesicular stomatitis virus (VSV) in mouse neuroblastoma and baby hamster kidney (BHK) cells. With the stereoscopic technique, progeny viruses at the cell surface and within the cytoplasm...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000148939
更新日期:1978-01-01 00:00:00
abstract::We examined influenza virus strains of the subtype H3N2 from outbreaks of respiratory diseases in swine herds in Germany. Four different clusters can be distinguished when comparing parts of the HA1 gene from porcine H3N2 isolates analyzed between 1982 and 2001. Comparison between these clusters reveals a bp homology ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000077829
更新日期:2004-01-01 00:00:00
abstract::The ability to discriminate between herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) infections by serological means is of increasing importance for clinical virological diagnostics. HSV type-specific serology has a number of applications, e.g. to guide duration and dosage of antiviral therapy, to allow for string...
journal_title:Intervirology
pub_type: 杂志文章,评审
doi:10.1159/000150493
更新日期:1996-01-01 00:00:00
abstract::Two DNA-negative temperature-sensitive mutants of human cytomegalovirus strain AD169 were shown to be deficient in induction of several prominent viral polypeptides when grown in human foreskin fibroblasts under nonpermissive conditions. The use of a monospecific polyclonal antiserum allowed recognition of a further d...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150034
更新日期:1988-01-01 00:00:00
abstract::To evaluate the diagnostic value of nucleic-acid-sequence-based amplification (NASBA) for the detection of cytomegalovirus (CMV) infection in transplant recipients, we compared immediate early 1 (IE1) and late pp67 mRNA detection by NASBA with the antigenemia assay, PCR and viral culture in 72 renal transplant (RTx) r...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000053974
更新日期:1999-01-01 00:00:00
abstract::Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000496828
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Torque teno virus (TTV) is a ubiquitous virus that is commonly associated with blood transfusion. The main aims of this study were to evaluate the incidence of TTV in polytransfused children with thalassemia and to determine for the first time the prevalent TTV genotypes in Egypt. METHODS:TTV was detected in...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000480507
更新日期:2017-01-01 00:00:00
abstract::To identify specific environmental, viral, and genetic risk factors for hepatocellular carcinoma (HCC) and the interaction of such factors, we are conducting a prospective study in a high-incidence area of China. Questionnaires were completed and biosamples collected by 60,984 men ages 30-64 years, at study entry. Wit...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150426
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to attain molecular knowledge of human papillomavirus type 18 (HPV18) by sequencing the whole genome of HPV18 isolated from Thai women at various clinical stages of disease progression. METHOD:Our group analyzed 9 samples of whole-genome HPV18 in infected women ranging from normal t...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000274977
更新日期:2010-01-01 00:00:00
abstract::Immunopathologic mechanisms leading to liver tissue injury in hepatitis caused by hepatitis A virus (HAV) were studied in an autologous in vitro model. Data show virus-specific killing by liver-infiltrating T lymphocytes in man and support the hypothesis that hepatocellular damage as well as efficient elimination of v...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150304
更新日期:1993-01-01 00:00:00
abstract::The envelope glycoprotein of the mouse mammary tumor virus (MMTV gp52), a useful plasma marker for mammary tumors in mice, was measured in extracellular medium by radioimmunoassay to quantitatively compare gp52 levels released by a C3H MMTV producer and its subcloned B9 nonproducer cell line. Experiments analyzed leve...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150081
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:In this study we established a mouse brain injection system to detect infectious dengue-2 virus produced from the full-length RNA transcripts. METHODS:In vitro transcription was used to synthesize full-length dengue-2 virus RNA from the plasmid pRS424FLDEN2NGC, which was intracerebrally injected into the 6-d...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000081744
更新日期:2005-01-01 00:00:00
abstract::Scrapie brain homogenate was mixed with mouse peritoneal macrophages in vitro. After 2 h of incubation at 37 degrees, a portion of the scrapie infectivity was associated with macrophages. In contrast, very little infectivity was associated with kidney cells that had been exposed to scrapie brain homogenate. After incu...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149241
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVES:To express E1 glycoprotein of rubella virus (RuV) strain JR23 in yeast and develop a diagnostic assay using expressed E1 protein as coating antigen in comparison with other diagnostic assays. METHODS:cDNA of E1 open reading frame of RuV was PCR amplified using plasmid pMD18-T-E1 as template and cloned into ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000085101
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND/AIMS:Cardiovirus is a genus of viruses belonging to the family Picornaviridae. Here, we used viral metagenomic techniques to detect the viral nucleic acid in the fecal samples from wild rats in Zhenjiang city in China. METHOD:Fecal samples were collected from 20 wild rats and pooled into four sample pools a...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000500555
更新日期:2019-01-01 00:00:00
abstract::Despite frequent statements to the contrary, there are good animal models for AIDS. In this review, we summarize the properties of one of the most useful animal models: infection of rhesus monkeys with simian immunodeficiency virus (SIV). The SIVs are an extensive group of HIV-related lentiviruses of nonhuman primates...
journal_title:Intervirology
pub_type: 杂志文章,评审
doi:10.1159/000150108
更新日期:1989-01-01 00:00:00
abstract::The morphology, assembly, and accumulation sites of rhabdovirus particles in Peregrinus maidis planthoppers infected with a Hawaiian isolate of maize mosaic virus (MMV) were studied. These particles were usually bullet-shaped, but were sometimes bacilliform, and averaged 234 and 247 nm, respectively, in length and 60 ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149616
更新日期:1985-01-01 00:00:00
abstract::Antibodies of individuals infected with the human immunodeficiency virus type 1 (HIV-1) were used to probe the antigenicity of the HIV-1 transmembrane protein of 41 kD (gp41) by antibody-reactive peptide scanning (Pepscan). Eleven distinct sequential antibody-binding sites were defined by testing reactivity to 339 ove...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150169
更新日期:1990-01-01 00:00:00
abstract::Healthy common marmosets from two separate colonies, one in England and one in France, were found to have antibodies cross-reacting with Epstein-Barr virus structural antigens (EBV-VCA). All seropositive animals were at least 2 years old. Experimental EBV infection of marmosets of different ages led to seroconversion ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149198
更新日期:1980-01-01 00:00:00
abstract::The use of bleach (hypochlorite) as a disinfectant for drug injection equipment in the intravenous-drug-using population was recommended early in the HIV-1/AIDS epidemic. Epidemiological studies have challenged the use of bleach as an effective measure to prevent HIV-1 transmission. However, in vitro HIV-1 coculture s...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000025015
更新日期:2000-01-01 00:00:00