Abstract:
:The critical point dried (CPD) whole cell technique was applied to the study of the morphogenesis and morphology of rabies virus and vesicular stomatitis virus (VSV) in mouse neuroblastoma and baby hamster kidney (BHK) cells. With the stereoscopic technique, progeny viruses at the cell surface and within the cytoplasm of the CPD whole cells were clearly visualized. The presence of many fine cellular processes and of virus budding from these processes were prominent features of the infected cells. Long strings of virus particles and virus apparently fused into different forms were often seen; a possible mechanism for the formation of these aberrant forms is discussed. Negative staining of the CPD whole cells clearly revealed the detailed structure of virus particles in the process of budding.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Iwasaki Ydoi
10.1159/000148939subject
Has Abstractpub_date
1978-01-01 00:00:00pages
214-25issue
4eissn
0300-5526issn
1423-0100journal_volume
9pub_type
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