Abstract:
:The early gene products of simian virus 40 (SV40) transform human fibroblasts, whereas those of the human papovavirus BK (BKV) do not. The early gene products of both SV40 and BKV transform baby rat kidney cells. SV40-BKV chimerics were constructed which were able to transform baby rat kidney cells. Using the SV40-BKV chimerics, two domains within the SV40 large T protein were identified which are involved in the transformation of human fibroblasts.
journal_name
Intervirologyjournal_title
Intervirologyauthors
de Ronde A,Sol CJ,MacDonald ME,Koot M,ter Schegget J,van Strien A,Wouters E,van der Noordaa Jdoi
10.1159/000150019subject
Has Abstractpub_date
1987-01-01 00:00:00pages
221-31issue
4eissn
0300-5526issn
1423-0100journal_volume
28pub_type
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