Abstract:
:Acute hemorrhagic conjunctivitis (AHC) virus strains isolated in eight different areas during epidemics of AHC were tested for the reproductive capacity at 33, 37 and 39 degrees. All of the 25 strains tested grew better at 33 degrees but restrictively at 39 degrees. The degree of temperature sensitivity varied slightly from one strain to the other, but generally exceeded that of attenuated poliovirus type 1, strain LSc2ab. Temperature-resistant clones were selected by repeated passages of originally temperature-sensitive prototype strains at supraoptimal temperature. The importance of using a low temperature (32-34 degrees) for isolation of virus from external tissues of the body and for subsequent passages has been emphasized. It was suggested that the relatively low temperature of the conjunctiva has played a role in perpetuating temperature sensitivity of this virus.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Miyamura K,Sasagawa A,Tajiri E,Kono Rdoi
10.1159/000149952subject
Has Abstractpub_date
1976-01-01 00:00:00pages
192-200issue
4-5eissn
0300-5526issn
1423-0100journal_volume
7pub_type
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