In vitro interaction of scrapie agent and mouse peritoneal macrophages.

abstract：BACKGROUND/AIMS:The present study was launched to systematically characterize the molecular genotypes and quantitative serological biomarkers during the natural course of chronic hepatitis B (CHB) infection in a patient population from Chongqing, China. METHODS:A total of 140 patients were enrolled and grouped accordi...

journal_title：Intervirology

authors： Xiang Y,Huang S,Xia J,Ye D,Chen P,Zhang L

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Many efforts are currently focused on functional treatment of the hepatitis B virus (HBV). This can be done by suppressing the secretion of HBV surface antigen (HBsAg). Scientific communities are very interested in natural products in that respect. OBJECTIVE:Use of root extract of Havachoobe (Onosma dichroa...

journal_title：Intervirology

authors： Mohebbi A,Azadi F,Hashemi MM,Askari FS,Razzaghi N

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVE:The genetic barrier for the evolution of integrase inhibitors (INIs) including raltegravir (RAL), elvitegravir (EVG), and dolutegravir (DTG) resistance was compared between HIV-1 subtypes CRF01_AE and B. METHODS:Analysis of 66 substitutions associated with INI resistance at 41 amino acid positions in 144 nuc...

journal_title：Intervirology

authors： Nguyen HL,Ruxrungtham K,Delaugerre C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We have recently demonstrated that an oligodeoxynucleotide (ODN) can enter HIV particles and form a local hybrid at the highly conserved polypurine tract (PPT), the target site of the ODN. This hybrid is recognized by the retrovirus-specific RNase H, which is a virion-associated enzyme. It cleaves the RNA at...

journal_title：Intervirology

authors： Heinrich J,Schols D,Moelling K

更新日期：2012-01-01 00:00:00

abstract：:The envelope glycoprotein of the mouse mammary tumor virus (MMTV gp52), a useful plasma marker for mammary tumors in mice, was measured in extracellular medium by radioimmunoassay to quantitatively compare gp52 levels released by a C3H MMTV producer and its subcloned B9 nonproducer cell line. Experiments analyzed leve...

journal_title：Intervirology

authors： Ritzi EM,Walthall EB

更新日期：1989-01-01 00:00:00

abstract：:Double-filtration plasmapheresis (DFPP) was approved in Japan in April 2008 for the retreatment of chronic hepatitis C patients with genotype 1b and high viral loads, whose hepatitis C virus was not eradicated by earlier IFN therapy or by pegylated IFN plus ribavirin (PEG-IFN/RBV) combination therapy. In this study, w...

journal_title：Intervirology

authors： Kim SR,Imoto S,Kudo M,Mita K,Taniguchi M,Kim KI,Sasase N,Shoji I,Nagano-Fujii M,El-Shamy A,Hotta H,Nagai T,Nagata Y,Hayashi Y

更新日期：2010-01-01 00:00:00

abstract：:Echinochloa ragged stunt virus (ERSV) and rice ragged stunt virus (RRSV; Reoviridae) were purified from their respective host plants and disrupted in SDS. Evidence for the double-strandedness of ERSV RNA was obtained. Electrophoresis in 10% polyacrylamide gels resolved the RNAs of each virus into 10 segments, ranging ...

journal_title：Intervirology

authors： Chen CC,Hsu YH,Chen MJ,Chiu RJ

更新日期：1989-01-01 00:00:00

abstract：:An amyloid-like isoform of a 33- to 34-kD glycoprotein, termed as the scrapie prion protein (PrPsc), plays a critical role in transmissible spongiform encephalopathies of animals and humans. It has even been suggested to present the responsible infectious agent. This protein is a posttranslationally modified form of t...

journal_title：Intervirology

authors： Tanji K,Saeki K,Matsumoto Y,Takeda M,Hirasawa K,Doi K,Matsumoto Y,Onodera T

更新日期：1995-01-01 00:00:00

abstract：:9-beta-D-Arabinofuranosyladenine (ara A) was shown to inhibit a specific step of tobacco mosaic virus (TMV) multiplication. The time course of the ara A-sensitive function occurred 'late' coinciding with the period of viral RNA and protein synthesis. When treatment began after viral RNA synthesis was established, 1.0 ...

journal_title：Intervirology

authors： Dawson WO,Lozoya-Saldana H

更新日期：1986-01-01 00:00:00

abstract：:The critical point dried (CPD) whole cell technique was applied to the study of the morphogenesis and morphology of rabies virus and vesicular stomatitis virus (VSV) in mouse neuroblastoma and baby hamster kidney (BHK) cells. With the stereoscopic technique, progeny viruses at the cell surface and within the cytoplasm...

journal_title：Intervirology

authors： Iwasaki Y

更新日期：1978-01-01 00:00:00

abstract：:The actinomycin-D(AMD)-sensitive step of replication of three plant viruses - cowpea chlorotic mottle virus (CCMV), cowpea mosaic virus, and the cowpea strain of tobacco mosaic virus - in cowpea was specific for each virus. Different combinations of the viruses were examined in which leaves were inoculated with one vi...

journal_title：Intervirology

authors： Turner MS,Dawson WO

更新日期：1984-01-01 00:00:00

abstract：:The leukocyte migration inhibition (LMI) technique was used to measure the T cell-mediated immune response of Epstein-Barr-virus (EBV)-seropositive human donors to antigens associated with B cell lines of simian origin, transformed by simian EBV-like viruses, Herpesvirus papio (HVP), H. pan, H. gorilla and H. pongo. E...

journal_title：Intervirology

authors： Szigeti R,Rabin H,Timar L,Klein G

更新日期：1986-01-01 00:00:00

abstract：:Influenza PR8 particles resulting from strong treatment with caseinase C are spikeless, devoid of neuraminidase and hemagglutinin 1 and 2 glycopeptides, and contain a Schiff-negative polypeptide of about 13,000 molecular weight which exists as traces in intact virions. Their M-protein polypeptide content is reduced to...

journal_title：Intervirology

authors： Reginster M,Rentier B,Dierickx L

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:Cervical cancer is the third most common malignancy in females. Since the human papillomavirus (HPV) genotype can vary geographically, it is essential to define its genotypic distribution before establishing health care policies and vaccination programs in any given area. The aim of this study was to determin...

journal_title：Intervirology

authors： Taghizadeh E,Taheri F,Abdolkarimi H,Ghorbani Renani P,Gheibi Hayat SM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Although human leukocyte antigens (HLA) have been shown in association with the outcomes of hepatitis C virus (HCV) infection among different ethnic groups, such studies remain absent in China, where the HCV prevalence is higher than the global average. METHODS:In this study, 426 HCV-infected and 709 uninfe...

journal_title：Intervirology

authors： Xiong H,Huang J,Rong X,Zhang M,Huang K,Xu R,Wang M,Li C,Liao Q,Xia W,Luo G,Ye X,Lu L,Fu Y,Guo T,Nelson K

更新日期：2015-01-01 00:00:00

abstract：:Infection with hepatitis B virus (HBV) continues to be a major problem in the human population. There remains a specific requirement for HBV vaccines capable of circumventing the non-responder/inadequate responder status of some vaccinees. Hepacare has been primarily developed to (1) improve anti-SHBs antibody titres ...

journal_title：Intervirology

authors： Page M,Jones CD,Bailey C

更新日期：2001-01-01 00:00:00

abstract：:The amino acid sequences of the virion proteins of 7 definitive tobamoviruses have been compared. The results show that the proteins may be arranged unequivocally in a single dendrogram which, by analogy with similar comparisons of other sets of homologous proteins, probably reflects their phylogeny. The magnitude of ...

journal_title：Intervirology

authors： Gibbs A

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cardiovirus is a genus of viruses belonging to the family Picornaviridae. Here, we used viral metagenomic techniques to detect the viral nucleic acid in the fecal samples from wild rats in Zhenjiang city in China. METHOD:Fecal samples were collected from 20 wild rats and pooled into four sample pools a...

journal_title：Intervirology

authors： Mahmood A,Shama S,Ni H,Wang H,Ling Y,Xu H,Yang S,Naseer QA,Zhang W

更新日期：2019-01-01 00:00:00

abstract：:Bovine adenoviruses (BAVs) are important pathogens causing significant economic losses to the cattle industry. We have been interested in the differences among serotypes of these viruses, particularly in their pathogenicity and host range. As part of our efforts to better understand these viruses, we have determined t...

journal_title：Intervirology

authors： Yagubi A,Ojkic D,Bautista DS,Haj-Ahmad Y

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Human Salivirus (SalV) has been associated with gastroenteritis on all continents. METHODS:This paper presents the real-time RT-PCR assay for the detection of SalV in clinical fecal samples collected from 192 hospitalized children with acute gastroenteritis in Piedmont, Italy. RESULTS:The most commonly dete...

journal_title：Intervirology

authors： Bergallo M,Daprà V,Rassu M,Bonamin S,Cuccu R,Calvi C,Montanari P,Galliano I

更新日期：2018-01-01 00:00:00

abstract：:Among patients undergoing maintenance hemodialysis, a high prevalence of hepatitis C virus (HCV) infection can be observed. In a prospective study, sera of 273 patients were examined for the presence of HCV infection by serological tests and by PCR. Thirty-five patients (12.8%) were HCV antibody positive, and in 31 of...

journal_title：Intervirology

authors： Schröter M,Feucht HH,Schäfer P,Zöllner B,Laufs R

更新日期：1997-01-01 00:00:00

abstract：:The complete sequence of the single-stranded, positive-sense RNA genome of pea stem necrosis virus (PSNV) has been determined. The 4,048-nucleotide genome contains five open reading frames (ORFs). The 5'-proximal ORF encodes a 25-kD protein (p25). If the amber termination codon is read through, the ORF produces a read...

journal_title：Intervirology

authors： Suzuki S,Hase S,Takahashi H,Ikegami M

更新日期：2002-01-01 00:00:00

abstract：:Two DNA-negative temperature-sensitive mutants of human cytomegalovirus strain AD169 were shown to be deficient in induction of several prominent viral polypeptides when grown in human foreskin fibroblasts under nonpermissive conditions. The use of a monospecific polyclonal antiserum allowed recognition of a further d...

journal_title：Intervirology

authors： Radsak K,Kaiser CJ,Haustein D,Rapp F

更新日期：1988-01-01 00:00:00

abstract：:The kinetics of Aleutian disease virus (ADV) replication in mink lymphocytes was followed by the analysis of virus-specific antigens, infectious virus, and viral DNA. Stimulation with pokeweed mitogen (PWM; 20 micrograms/ml) increased the synthesis of ADV DNA in cultivated cells of the B-cell fraction. Maximum virus t...

journal_title：Intervirology

authors： Kaaden OR,Haas L,Löchelt M,Roth S

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:In this study we established a mouse brain injection system to detect infectious dengue-2 virus produced from the full-length RNA transcripts. METHODS:In vitro transcription was used to synthesize full-length dengue-2 virus RNA from the plasmid pRS424FLDEN2NGC, which was intracerebrally injected into the 6-d...

journal_title：Intervirology

authors： Lee YR,Huang KJ,Lei HY,Chen SH,Lin YS,Yeh TM,Liu HS

更新日期：2005-01-01 00:00:00

abstract：:Monoclonal antibodies were used to study measles virus (Hallé strain) infections. The distribution of virus antigens in acutely and persistently infected cells was examined by immunofluorescence, and the synthesis of the virus polypeptides in acutely infected cells was measured after immunoprecipitation and analysis i...

journal_title：Intervirology

authors： Giraudon P,Gerald C,Wild TF

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVES:Data on drug-resistant mutations (DRMs) in HIV-1-infected therapy-naïve children are scarce. The aim of this study was to determine the HIV-1 subtype distribution and the prevalence of DRMs in therapy-naïve HIV-1-infected children who received routine care at the University Hospital Düsseldorf, Düsseldorf, G...

journal_title：Intervirology

authors： Neubert J,Michalsky N,Laws HJ,Borkhardt A,Jensen B,Lübke N

更新日期：2016-01-01 00:00:00

abstract：:The interaction of Autographa californica nuclear polyhedrosis virus with two nonpermissive cell lines was investigated. The insect cell line, CP 169, and the Chinese hamster cell line, CHO-K1, were able to adsorb and engulf virus particles, but there was no evidence for viral replication in these cells based on virus...

journal_title：Intervirology

authors： Gröner A,Granados RR,Burand JP

更新日期：1984-01-01 00:00:00

abstract：:6/94 virus, isolated originally from a multiple sclerosis (MS) patient, was compared antigenically with related parainfluenza type 1 strains. These included two Sendai strains of mouse and two Sendai strains of reported human origin as well as the HA2 strain. By standard hemagglutination inhibition (HI) or hemadsorpti...

journal_title：Intervirology

authors： Lief FS,Loh W,Meulen VT,Koprowski H

更新日期：1975-01-01 00:00:00

abstract：:The mainstay of therapy for patients with chronic hepatitis B is inhibition of the replicative cycle of hepatitis B virus (HBV) in hepatocytes. Antiviral agents have different potencies. The measurement of HBV DNA in serum can monitor the potency of these therapeutic agents. Viral breakthrough may occur during therapy...

journal_title：Intervirology

authors： Leung N

更新日期：2003-01-01 00:00:00