Interaction of Autographa californica nuclear polyhedrosis virus with two nonpermissive cell lines.

abstract：:Double-filtration plasmapheresis (DFPP) was approved in Japan in April 2008 for the retreatment of chronic hepatitis C patients with genotype 1b and high viral loads, whose hepatitis C virus was not eradicated by earlier IFN therapy or by pegylated IFN plus ribavirin (PEG-IFN/RBV) combination therapy. In this study, w...

journal_title：Intervirology

authors： Kim SR,Imoto S,Kudo M,Mita K,Taniguchi M,Kim KI,Sasase N,Shoji I,Nagano-Fujii M,El-Shamy A,Hotta H,Nagai T,Nagata Y,Hayashi Y

更新日期：2010-01-01 00:00:00

abstract：:Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antige...

journal_title：Intervirology

authors： Norrild B,Vestergaard BF

更新日期：1979-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) induces chronic liver disease in hosts which can eventually progresses to liver cirrhosis and hepatocellular carcinoma. However, progression of liver disease is slower in patients with persistently normal levels of alanine aminotransferase (ALT) than in those with active hepatitis. Although dis...

journal_title：Intervirology

authors： Kanto T,Inoue M,Miyazaki M,Itose I,Miyatake H,Sakakibara M,Yakushijin T,Kaimori A,Oki C,Hiramatsu N,Kasahara A,Hayashi N

更新日期：2006-01-01 00:00:00

abstract：:A SmaI map of class I defective DNA of herpes simplex virus type 1 (HSV1) was constructed using a set of deletion hybrid phages. Four SmaI fragments on the defective DNA had a variability in length common among 15 HSV1 isolates: the 1.45 kilobase (kb) fragment located within the BamHI-Z (map coordinates 0.936-0.949) f...

journal_title：Intervirology

authors： Umene K

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the mutational patterns on the pol gene of the main HIV-1 strain archived in cell genome of 10 chronically infected men according to their clinical and therapeutic history. The genotyping resistance profiles were compared between the first blood plasma available at the time of HIV diagnosis and re...

journal_title：Intervirology

authors： Depincé AE,Dussert E,Vergnon-Miszczycha D,Keita A,Pillet S,Botelho-Nevers E,Frésard A,Gagneux-Brunon A,Lucht FR,Roblin X,Pozzetto B,Paul S,Bourlet T

更新日期：2016-01-01 00:00:00

abstract：:The complete sequence of the single-stranded, positive-sense RNA genome of pea stem necrosis virus (PSNV) has been determined. The 4,048-nucleotide genome contains five open reading frames (ORFs). The 5'-proximal ORF encodes a 25-kD protein (p25). If the amber termination codon is read through, the ORF produces a read...

journal_title：Intervirology

authors： Suzuki S,Hase S,Takahashi H,Ikegami M

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Giant viruses of the Megavirales order have been neglected in the literature because they are removed from samples during viral purification for viral metagenomic studies. Isolation via amoeba coculture has low efficiency and is extremely time-consuming. Thus, our objective was to improve Megavirales detectio...

journal_title：Intervirology

authors： Slimani M,Pagnier I,Boughalmi M,Raoult D,La Scola B

更新日期：2013-01-01 00:00:00

abstract：:Studies of human papillomavirus (HPV) infection are hampered by the lack of an adequate culture system. The athymic mouse xenograft system permits propagation of HPV, but only a few HPV types have been grown in this manner. To produce an oncogenic type for studies of HPV pathogenesis, a condylomata acuminata lesion fr...

journal_title：Intervirology

authors： Bryan JT,Tekchandani J,Schroeder JM,Brown DR

更新日期：2000-01-01 00:00:00

abstract：:In Spodoptera frugiperda (SF IPLB-21) cells productively infected with S. frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV), we observed the synthesis of infected-cell-specific polypeptides (ICSPs) using the protein synthesis inhibitor cycloheximide (CX) and the DAN synthesis inhibitor cytosine arabinoside (A...

journal_title：Intervirology

authors： Liu HS,Bilimoria SL

更新日期：1997-01-01 00:00:00

abstract：AIMS:The objective of this work was to study the distribution of hepatitis C virus (HCV) genotypes and subtypes from 2010 to 2015 in 1,221 anti-HCV/HCV-RNA-positive specimens from patients living in the metropolitan area of Naples, since HCV genotypes and subtypes remain cornerstones in the management of chronic HCV in...

journal_title：Intervirology

authors： Grimaldi E,Della Pepa ME,Martora F,Magliocca P,Iovene MR,Coppola N,Donnarumma G,Galdiero M

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The genetic barrier for the evolution of integrase inhibitors (INIs) including raltegravir (RAL), elvitegravir (EVG), and dolutegravir (DTG) resistance was compared between HIV-1 subtypes CRF01_AE and B. METHODS:Analysis of 66 substitutions associated with INI resistance at 41 amino acid positions in 144 nuc...

journal_title：Intervirology

authors： Nguyen HL,Ruxrungtham K,Delaugerre C

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The open reading frame 8 (ORF8) within the short unique (U(s)) region of the bovine herpesvirus 1 (BHV-1) genome was predicted to encode a protein with homology to U(s)9 protein of other alpha herpesviruses. The aim of this study is to identify the protein encoded by the U(s) ORF8 and to examine the effect of...

journal_title：Intervirology

authors： Nakamichi K,Matsumoto Y,Tohya Y,Otsuka H

更新日期：2002-01-01 00:00:00

abstract：:In order to evaluate the usefulness of cytomegalovirus (CMV) antibody screening during pregnancy, women attending for antenatal care at the Antoine Béclère Hospital (Clamart, France) were prospectively studied during 22 months (1995-1996). Forty-five percent of these women were CMV-seropositive. Twenty suspected or co...

journal_title：Intervirology

authors： Grangeot-Keros L,Simon B,Audibert F,Vial M

更新日期：1998-01-01 00:00:00

abstract：:There are two major requirements for potyvirus taxonomy; group-specific criteria and criteria which discriminate between distinct viruses and strains. This review discusses the relative merits in potyvirus taxonomy of molecular parameters, such as gene sequence data, nucleic acid hybridization, coat protein sequence d...

journal_title：Intervirology

authors： Ward CW,Shukla DD

更新日期：1991-01-01 00:00:00

abstract：:SDS-polyacrylamide slab gel analysis of selected primate and nonprimate adenoviruses has shown these viruses to differ significantly at the polypeptide molecular level. It follows that data derived from study of a single adenovirus serotype are unique to that serotype and are not representative of the adenovirus group...

journal_title：Intervirology

authors： Marusyk RG,Cummings GT

更新日期：1978-01-01 00:00:00

abstract：:Three independently isolated herpes simplex virus type 1 recombinant viruses containing a deletion of approximately 14 kilobase pairs, representing greater than 95% of the internal repeat DNA sequences, were analyzed for their pathogenicity in mice. The recombinant viruses were found to be avirulent, exhibiting drasti...

journal_title：Intervirology

authors： Jenkins FJ,Martin JR

更新日期：1990-01-01 00:00:00

abstract：:By a combination of PCR and direct-cycle sequencing using consensus primers, we analyzed approximately 400-bp fragments within the NS3 genes of twenty-one dengue virus type 3 strains isolated from five neighboring Southeast Asian countries at different time intervals from 1956 to 1992. The majority of base disparities...

journal_title：Intervirology

authors： Chow VT,Seah CL,Chan YC

更新日期：1994-01-01 00:00:00

abstract：:The morphology, assembly, and accumulation sites of rhabdovirus particles in Peregrinus maidis planthoppers infected with a Hawaiian isolate of maize mosaic virus (MMV) were studied. These particles were usually bullet-shaped, but were sometimes bacilliform, and averaged 234 and 247 nm, respectively, in length and 60 ...

journal_title：Intervirology

authors： Ammar ED,Nault LR

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:Characterization of the phylogeny and diversity of human respiratory syncytial virus (HRSV) genotype ON1 that occurred during its early evolution (within the first 3.5 years since the detection of the first ON1 strains). ON1 strains have a 72-nucleotide-long in-frame duplication within the second hypervariabl...

journal_title：Intervirology

authors： Ivancic-Jelecki J,Forcic D,Mlinaric-Galinovic G,Tesovic G,Nikic Hecer A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin molecule of influenza virus is considered as an ideal model to study biological processes as well as the effect of glycosylation on the function of glycoproteins. OBJECTIVES:The large subunit of the influenza virus A/New Caledonia/20/99 (H1N1) hemagglutinin (HA1) was expressed in recombina...

journal_title：Intervirology

authors： Farahmand B,Khodabandeh M,Mahboudi F,Fotouhi F,Saleh M,Barkhordari F,Tabatabaian M,Nasab FP,Kheiri MT

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Because the determination of the stage of fibrosis depends on rather subjective judgment, more objective parameters are needed. In this study, we followed the long-term outcome, with monitoring of platelet counts, in patients with chronic hepatitis C or liver cirrhosis (LC) who had undergone interferon (IFN) ...

journal_title：Intervirology

authors： Moriyama M,Matsumura H,Aoki H,Shimizu T,Nakai K,Saito T,Yamagami H,Shioda A,Kaneko M,Goto I,Tanaka N,Arakawa Y

更新日期：2003-01-01 00:00:00

abstract：:One hundred and twenty-one chronic hepatitis C patients were administered interferon (IFN) and divided into two groups: 31 complete responders (CR) with prolonged HCV-RNA negative 1 year after treatment and 90 non-complete responders (non-CR), including partial responders (PR) with transiently negative HCV-RNA and non...

journal_title：Intervirology

authors： Kim KI,Sasase N,Taniguchi M,Mita K,Kim SR,Tanaka K,Hayashi Y

更新日期：2005-01-01 00:00:00

abstract：:The leukocyte migration inhibition (LMI) technique was used to measure the T cell-mediated immune response of Epstein-Barr-virus (EBV)-seropositive human donors to antigens associated with B cell lines of simian origin, transformed by simian EBV-like viruses, Herpesvirus papio (HVP), H. pan, H. gorilla and H. pongo. E...

journal_title：Intervirology

authors： Szigeti R,Rabin H,Timar L,Klein G

更新日期：1986-01-01 00:00:00

abstract：:The aim of the study was to determine the prevalence of drug resistance of HIV-1 in pediatric patients from Istanbul, Turkey. Genotypic drug resistance testing revealed transmission of drug resistance from mother to child in 20%. Due to rising numbers of children with HIV-1, baseline resistance testing is recommended ...

journal_title：Intervirology

authors： Yoldaş O,Ağaçfidan A,Lübke N,Somer A,Hançerli S,Verheyen J,Kaiser R,Akgül B

更新日期：2014-01-01 00:00:00

abstract：:When Vero cells infected with Junín virus are cultured in the presence of 16 mM glucosamine, no infectious virus is produced and no surface antigens or virions are detected. Cytoplasmic viral antigen, however, is synthesized normally. ...

journal_title：Intervirology

authors： Martínez Peralta LA,León ME,Coto CE,Laguens RP

更新日期：1979-01-01 00:00:00

abstract：:Two DNA-negative temperature-sensitive mutants of human cytomegalovirus strain AD169 were shown to be deficient in induction of several prominent viral polypeptides when grown in human foreskin fibroblasts under nonpermissive conditions. The use of a monospecific polyclonal antiserum allowed recognition of a further d...

journal_title：Intervirology

authors： Radsak K,Kaiser CJ,Haustein D,Rapp F

更新日期：1988-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 ...

journal_title：Intervirology

authors： Franci G,Crudele V,Della Rocca MT,Melardo C,Chianese A,Finamore E,Bencivenga F,Astorri R,Vitiello M,Galdiero E,Galdiero M

更新日期：2019-01-01 00:00:00

abstract：:Adult Hartley guinea pigs infected with guinea pig cytomegalovirus (CMV) develop a mononucleosis syndrome with a brief viremia, splenomegaly, lymphadenopathy, and peripheral lymphocytosis with circulating atypical lymphocytes. The present study used this experimental model to evaluate in vivo the therapeutic efficacy ...

journal_title：Intervirology

authors： Lucia HL,Griffith BP,Hsiung GD

更新日期：1984-01-01 00:00:00

abstract：:Solubilized envelope antigens (glycoproteins) of Sendai virus were purified in a DEAE-Bio-Gel A column. Monospecific antisera were prepared against the antigens, designated HN and F glycoproteins. These glycoproteins are antigenically distinct. Immunodiffusion analyses of the envelope antigens of three representative ...

journal_title：Intervirology

authors： Urata DM,Seto JT

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between enteroviral infection and myocardial tissue apoptosis during the development of viral myocarditis in a murine model. METHODS:C3H/HeJ mice were inoculated with two strains of coxsackievirus B3, specifically CVB3 (cardiovirulent Nancy strain) and CVB3/0 (noncardiovirulen...

journal_title：Intervirology

authors： Joo CH,Hong HN,Kim EO,Im JO,Yoon SY,Ye JS,Moon MS,Kim D,Lee H,Kim YK

更新日期：2003-01-01 00:00:00