Variability of the region of the herpes simplex virus type 1 genome yielding defective DNA: SmaI fragment polymorphism.

abstract：:A reverse transcriptase, polymerase chain reaction (RT-PCR) procedure was used to amplify a segment of the genome of turkey coronavirus (TCV) spanning portions of the matrix and nucleocapsid (MN) protein genes (approximately 1.1 kb). The MN gene region of three epidemiologically distinct TCV strains (Minnesota, NC95, ...

journal_title：Intervirology

authors： Breslin JJ,Smith LG,Fuller FJ,Guy JS

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Genome-wide sequences of hepatitis B virus strain associated with type B fulminant hepatitis have not been compared with those of acute self-limited hepatitis. We carried out full-length sequencing analysis of viral strains derived from patients with type B acute liver injury. METHODS:Nine acute self-limited...

journal_title：Intervirology

authors： Kanada A,Takehara T,Ohkawa K,Tatsumi T,Sakamori R,Yamaguchi S,Uemura A,Kohga K,Sasakawa A,Hikita H,Hijioka T,Katayama K,Deguchi M,Kagita M,Kanto T,Hiramatsu N,Hayashi N

更新日期：2007-01-01 00:00:00

abstract：:Serial passage of undiluted herpes simplex virus types 1 and 2 resulted in cyclic production of infectious and defective virions. Defective virus production was characterized by the appearance of a new species of viral DNA with a higher bouyant density in CsCl than standard viral DNA. Measurement of the infectivity ti...

journal_title：Intervirology

authors： Murray BK,Biswal N,Bookout JB,Lanford RE,Courtney RJ,Melnick JL

更新日期：1975-01-01 00:00:00

abstract：:Plants mixedly infected with the U2 strain of tobacco mosaic virus (T2MV) and sunnhemp mosaic virus (SHMV) and grown at 35 degrees, yield particles of the same modal lengths (300 and 40 nm) as those found in plants singly infected with SHMV, but not in plants infected with T2MV, which yield only the long particles. At...

journal_title：Intervirology

authors： Skotnicki A,Gibbs A,Shaw DC

更新日期：1976-01-01 00:00:00

abstract：:In order to assess the risk of transmission of viral diseases during floods, the viral burden in flooded areas of the city of Dresden (Germany) in August 2002 was investigated. Water samples were collected from 9 sampling sites and tested for the presence of 11 enteric viral pathogens. As a control, water samples from...

journal_title：Intervirology

authors： Rohayem J,Dumke R,Jaeger K,Schröter-Bobsin U,Mogel M,Kruse A,Jacobs E,Rethwilm A

更新日期：2006-01-01 00:00:00

abstract：:The mainstay of therapy for patients with chronic hepatitis B is inhibition of the replicative cycle of hepatitis B virus (HBV) in hepatocytes. Antiviral agents have different potencies. The measurement of HBV DNA in serum can monitor the potency of these therapeutic agents. Viral breakthrough may occur during therapy...

journal_title：Intervirology

authors： Leung N

更新日期：2003-01-01 00:00:00

abstract：:The genetic relationship between two enteroviruses causing the acute hemorrhagic conjunctivitis (AHC) syndrome was examined by the RNA-RNA hybridization technique. Nucleotide sequence homology between the J670/71 strain of enterovirus type 70 (EV70) and the EH 24/70 strain of Singapore epidemic conjunctivitis (SEC) vi...

journal_title：Intervirology

authors： Natori K,Yamazaki S,Miyamura K,Kono R

更新日期：1984-01-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) genetic diversity is one of the most important features of HIV-1 infections and the result of error accumulation during reverse transcription and of high viral turnover. HIV-1 reverse transcription is influenced by factors such as the level of nucleotides and/or the cellular...

journal_title：Intervirology

authors： Russo CT,Alkmim W,Munerato P,Zukurov J,Maricato JT,Sucupira MC,Diaz RS,Janini LM

更新日期：2014-01-01 00:00:00

abstract：:Previous reports documented the recovery of a DNA virus from a patient with posttransfusion non-A-G hepatitis and named TT virus (TTV). Although the virus was initially detected as a causative agent of hepatitis, there is doubt about its pathogenicity. The aim of this study was to clarify the relationship between TTV ...

journal_title：Intervirology

authors： Suzuki F,Chayama K,Tsubota A,Akuta N,Someya T,Kobayashi M,Suzuki Y,Saitoh S,Arase Y,Ikeda K,Kumada H

更新日期：2001-01-01 00:00:00

abstract：:HIV-2 is responsible for a limited epidemic in West Africa. Around 20% of all infected patients will progress to AIDS, and will need antiretroviral therapy. Unfortunately, antiretrovirals were developed to suppress HIV-1 replication; not all of them are active against HIV-2, e.g. all nonnucleoside reverse transcriptas...

journal_title：Intervirology

authors： Camacho RJ

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the distribution of hepatitis C virus (HCV) genotype and the possible association between genotype and HCV-associated liver disease in Indonesia. METHODS:32 anti-HCV-positive asymptomatic carriers (AC), 55 chronic hepatitis (CH), 41 liver cirrhosis (LC), and 35 hepato...

journal_title：Intervirology

authors： Utama A,Budiarto BR,Monasari D,Octavia TI,Chandra IS,Gani RA,Hasan I,Sanityoso A,Miskad UA,Yusuf I,Lesmana LA,Sulaiman A,Tai S

更新日期：2008-01-01 00:00:00

abstract：:The aim of the study was to determine the prevalence of drug resistance of HIV-1 in pediatric patients from Istanbul, Turkey. Genotypic drug resistance testing revealed transmission of drug resistance from mother to child in 20%. Due to rising numbers of children with HIV-1, baseline resistance testing is recommended ...

journal_title：Intervirology

authors： Yoldaş O,Ağaçfidan A,Lübke N,Somer A,Hançerli S,Verheyen J,Kaiser R,Akgül B

更新日期：2014-01-01 00:00:00

abstract：:The regulatory regions for transcription and replication of several hepatitis B virus (HBV) genomes from 19 patients having various forms of HBV infection were sequenced. Predominant mutations were found to occur naturally in nucleotide positions 1762 (A to T) and 1764 (G to A) in chronic hepatitis patients and in asy...

journal_title：Intervirology

authors： Nishizono A,Hiraga M,Kohno K,Sonoda YT,Terao H,Fujioka T,Nasu M,Mifune K

更新日期：1995-01-01 00:00:00

abstract：:An RNA virus was isolated from Trichoplusia ni larvae infected with inoculum of the baculovirus of Autographa californica. Physicochemical characterization has revealed a 35-nm virus with a density in CsCl of 1.3 g/cm3 and a sedimentation coefficient of 200S. The virus consisted of 10--15% single-stranded RNA with an ...

journal_title：Intervirology

authors： Morris TJ,Hess RT,Pinnock DE

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND/AIMS:In Zimbabwe, cervical cancer is screened through cytology and visual inspection with acetic acid and cervicography (VIAC). The effectiveness of these methods can be increased if complemented by a human papillomavirus DNA detection tool since most cervical cancer cases are caused by persistent infection ...

journal_title：Intervirology

authors： Marembo T,Dube Mandishora R,Borok M

更新日期：2019-01-01 00:00:00

abstract：:In chicken cells infected by Sindbis virus and exposed to a variety of membrane-active compounds, virus release was inhibited. In infected cells exposed to antiserum directed against the virion glycoproteins E1 or E2, retinol, cortisone, Pb++ or insulin, the processing of two Sindbis virus precursor polypeptides which...

journal_title：Intervirology

authors： Scupham RK,Sagik BP,Bose HR Jr

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Some patients with chronic hepatitis C virus (HCV) infection fail to achieve complete early virologic response (EVR) despite a marked decrease in HCV RNA at 4 weeks. We investigated the characteristics and final treatment outcomes of this patient subpopulation. METHODS:A total of 516 patients with HCV genoty...

journal_title：Intervirology

authors： Toyoda H,Kumada T,Shimada N,Takaguchi K,Ide T,Sata M,Ginba H,Matsuyama K,Izumi N

更新日期：2014-01-01 00:00:00

abstract：:Despite the existence for some time of effective prophylactic vaccines, hepatitis B virus (HBV) infection remains an important global concern. Improvements on existing vaccines could be beneficial, especially in situations where it is desirable or necessary to induce protective immunity more rapidly or with fewer dose...

journal_title：Intervirology

authors： Payette PJ,Ma X,Weeratna RD,McCluskie MJ,Shapiro M,Engle RE,Davis HL,Purcell RH

更新日期：2006-01-01 00:00:00

abstract：:The proposed family Toroviridae is characterized by eveloped, peplomer-bearing particles containing an elongated tubular nucleocapsid with helical symmetry. The capsid may bend into an open torus, conferring a biconcave disk or kidney-shaped morphology to the virion (largest diameter 120-140 nm) or the capsid may be s...

journal_title：Intervirology

authors： Horzinek MC,Flewett TH,Saif LJ,Spaan WJ,Weiss M,Woode GN

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between enteroviral infection and myocardial tissue apoptosis during the development of viral myocarditis in a murine model. METHODS:C3H/HeJ mice were inoculated with two strains of coxsackievirus B3, specifically CVB3 (cardiovirulent Nancy strain) and CVB3/0 (noncardiovirulen...

journal_title：Intervirology

authors： Joo CH,Hong HN,Kim EO,Im JO,Yoon SY,Ye JS,Moon MS,Kim D,Lee H,Kim YK

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:Chikungunya virus (CHIKV) is an alphavirus belonging to the Togaviridae family. Alphaviruses cause a chronic non-cytopathic infection in mosquito cells, while they develop a highly cytopathic infection in cells originating from various vertebrates. In this study, we compared the cytopathic effect (CPE) induc...

journal_title：Intervirology

authors： Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-nuegoonpipat A,Tao R,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

更新日期：2013-01-01 00:00:00

abstract：:In this study, 574 stool samples from children with gastroenteritis were obtained from different hospitals in Costa Rica, Honduras, Nicaragua and the Dominican Republic during 2005-2006. Diarrhea stool samples were analyzed for rotavirus by ELISA and typed by the RT-PCR-based method. Unusual strains were detected: G1P...

journal_title：Intervirology

authors： Bourdett-Stanziola L,Ortega-Barria E,Espinoza F,Bucardo F,Jimenez C,Ferrera A

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The specific effect of rna interference on the replication of porcine hemagglutinating encephalomyelitis virus (phe-cov) was explored. METHODS:Four species of small interfering RNA (siRNA), targeting different regions of the PHE-CoV spike glycoprotein and replicase polyprotein genes, were prepared by in vitr...

journal_title：Intervirology

authors： Lan Y,Lu H,Zhao K,He W,Chen K,Wang G,Song D,Gao F

更新日期：2012-01-01 00:00:00

abstract：:The purpose of our work was to determine if aerosols of Junin virus can infect rhesus macaques and if the disease is the same as that produced by virus inoculated parenterally. The 6 macaques exposed to the virus by aerosol became acutely ill during the 3rd week after exposure, and all died. Three died by day 21, whil...

journal_title：Intervirology

authors： Kenyon RH,McKee KT Jr,Zack PM,Rippy MK,Vogel AP,York C,Meegan J,Crabbs C,Peters CJ

更新日期：1992-01-01 00:00:00

abstract：:Genital infection with high-risk human papillomaviruses (HPV) has been etiologically linked with the development of cervical and other anogenital cancers. There is therefore a need for an effective HPV vaccine with the potential to significantly reduce the burden of more than half a million new cervical cancer cases i...

journal_title：Intervirology

authors： Kirnbauer R

更新日期：1996-01-01 00:00:00

abstract：:Monoclonal antibodies were used to study measles virus (Hallé strain) infections. The distribution of virus antigens in acutely and persistently infected cells was examined by immunofluorescence, and the synthesis of the virus polypeptides in acutely infected cells was measured after immunoprecipitation and analysis i...

journal_title：Intervirology

authors： Giraudon P,Gerald C,Wild TF

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (RSV) infection in infancy and early childhood causes acute bronchiolitis and exacerbates bronchial asthma. Eosinophil infiltration may contribute to airway obstruction in RSV infection. OBJECTIVE:We hypothesized that RSV affects eosinophil function. METHODS:Eosinophil act...

journal_title：Intervirology

authors： Tachibana A,Kimura H,Kato M,Nako Y,Kozawa K,Morikawa A

更新日期：2002-01-01 00:00:00

abstract：:The 20-nm noninfectious empty envelope particles carrying the hepatitis B surface antigen are secreted in large excess from hepatocytes during a hepatitis B infection. Similar particles produced in cell lines or yeast are an efficient vaccine against hepatitis B virus. We have analyzed the assembly of 20-nm particles ...

journal_title：Intervirology

authors： Prange R,Mangold CM,Hilfrich R,Streeck RE

更新日期：1995-01-01 00:00:00

abstract：:The PLC/PRF/5 human hepatoma cell line producing hepatitis B surface antigen (HBsAg) was studied to determine whether infectious hepatitis B virus (HBV) was also being produced. 2 chimpanzees with no previous exposure to HBV and no serologic markers of past or active HBV infection were inoculated intravenously with 50...

journal_title：Intervirology

authors： Tabor E,Copeland JA,Mann GF,Howard CR,Skelly J,Snoy P,Zuckerman AJ,Gerety RJ

更新日期：1981-01-01 00:00:00

abstract：:The ability to discriminate between herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) infections by serological means is of increasing importance for clinical virological diagnostics. HSV type-specific serology has a number of applications, e.g. to guide duration and dosage of antiviral therapy, to allow for string...

journal_title：Intervirology

authors： Bergström T,Trybala E

更新日期：1996-01-01 00:00:00