Abstract:
:Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antigen, was found in high concentration in the medium as compared to other HSV antigens released from HSV-1-infected cells. The HSV-2-specific antigens, Ag-4 and Ag-1, were released in molecular modifications with altered electrophoretic mobility as compared to their cellular counterparts. Purification of HSV antigens was performed by ion-exchange chromatography, and an HSV type-common antigen, Ag-11, and an HSV-2-specific antigen, Ag-4A, were isolated.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Norrild B,Vestergaard BFdoi
10.1159/000149020subject
Has Abstractpub_date
1979-01-01 00:00:00pages
104-10issue
2eissn
0300-5526issn
1423-0100journal_volume
11pub_type
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