Abstract:
:The distribution of related sequences between the genomes of pseudorabies virus (PRV) and herpes simplex virus, types 1 (HSV-1) and 2 (HSV-2), was determined. Approximately 7% of the sequences in PRV are shared by HSV-1 and HSV-2 DNAs. By means of the Southern blot technique, it was found that the homologous sequences are not sequestered in one region but are distributed throughout the PRV genome. HSV-1 and HSV-2 have the greatest homology with the long unique region of PRV DNA and the least with the inverted repeat regions of the molecule. HSV-1 DNA also has few sequences homologous to the short unique region of the PRV genome; HSV-2 DNA hybridizes well to this region. There was no homology of HSV-1 or HSV-2 DNAs with the extreme ends of the inverted repeat regions of PRV DNA.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Rand TH,Ben-Porat Tdoi
10.1159/000149106subject
Has Abstractpub_date
1980-01-01 00:00:00pages
48-53issue
1eissn
0300-5526issn
1423-0100journal_volume
13pub_type
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