Epstein-Barr Virus Seroprevalence and Primary Infection at the University Hospital Luigi Vanvitelli of Naples from 2007 to 2017.

Abstract:

:Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infection was higher in patients about 5 years old, while seropositivity for past infection was predominant in patients of about 35 years old. These results underline that children in our country are still exposed to EBV. The development and the deeper use of an EBV vaccine in the early years of life could represent the solution for this infection.

journal_name

Intervirology

journal_title

Intervirology

authors

Franci G,Crudele V,Della Rocca MT,Melardo C,Chianese A,Finamore E,Bencivenga F,Astorri R,Vitiello M,Galdiero E,Galdiero M

doi

10.1159/000496828

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

15-22

issue

1

eissn

0300-5526

issn

1423-0100

pii

000496828

journal_volume

62

pub_type

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