Polypeptide synthesis in human fibroblasts infected with DNA-negative mutants of cytomegalovirus.

abstract：OBJECTIVE:The aim of this study was to investigate the distribution of hepatitis C virus (HCV) genotype and the possible association between genotype and HCV-associated liver disease in Indonesia. METHODS:32 anti-HCV-positive asymptomatic carriers (AC), 55 chronic hepatitis (CH), 41 liver cirrhosis (LC), and 35 hepato...

journal_title：Intervirology

authors： Utama A,Budiarto BR,Monasari D,Octavia TI,Chandra IS,Gani RA,Hasan I,Sanityoso A,Miskad UA,Yusuf I,Lesmana LA,Sulaiman A,Tai S

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to investigate the molecular mechanism of hepatocellular carcinoma (HCC) development induced by hepatitis B virus X protein (HBx). METHODS:We previously established a H7402-X cell line that constitutively expresses HBx protein. In the present study, H7402-X gene expression profiles a...

journal_title：Intervirology

authors： Ye L,Dong N,Wang Q,Xu Z,Cai N,Wang H,Zhang X

更新日期：2008-01-01 00:00:00

abstract：:We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

journal_title：Intervirology

authors： Simard C,LaBoissière S,Séguin C,Trudel M

更新日期：1991-01-01 00:00:00

abstract：:The intracellular fate of 3H-labeled exogenous herpes simplex virus type 2 DNA following the exposure of recipient cells to selected DNA facilitators and the ultrastructural changes which ensued in transfected cultures were examined. In most cases, electron microscopic radioautography demonstrated that exogenous DNA r...

journal_title：Intervirology

authors： Marciano-Cabral F,Cabral GA,Taylor MM,Patterson M,Farber FE

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:The specific effect of rna interference on the replication of porcine hemagglutinating encephalomyelitis virus (phe-cov) was explored. METHODS:Four species of small interfering RNA (siRNA), targeting different regions of the PHE-CoV spike glycoprotein and replicase polyprotein genes, were prepared by in vitr...

journal_title：Intervirology

authors： Lan Y,Lu H,Zhao K,He W,Chen K,Wang G,Song D,Gao F

更新日期：2012-01-01 00:00:00

abstract：:Viroids are minute unencapsidated non-coding circular RNAs known to be present and to cause diseases only in plants. Infections were associated with the occurrence of specific single-stranded RNAs similar in size to miRNAs and endogenous small interfering RNAs, and viroid pathogenicity is suspected to occur through RN...

journal_title：Intervirology

authors： Bengone-Abogourin JG,Chelkha N,Verdin E,Colson P

更新日期：2019-01-01 00:00:00

abstract：:The reactivity of sera from patients with cervical cancer with the E7 protein of human papilloma virus type 16 (HPV16) was estimated using a novel non-radioactive immunoprecipitation assay and four established protein- and peptide-based immunoassays. Six of 14 sera from patients with cervical cancer and 1 of 10 sera f...

journal_title：Intervirology

authors： Malcolm K,Meschede W,Pawlita M,Koutsky LA,Frazer IH

更新日期：2000-01-01 00:00:00

abstract：:Dengue and chikungunya fevers are transmitted by the common mosquito vector Aedes and malaria by Anopheles. Concurrent infections are reported due to co-circulation of these pathogens, especially in endemic regions. We report a rare case of triple infection with 3 arthropod-borne pathogens (Plasmodium vivax and the de...

journal_title：Intervirology

authors： Tazeen A,Abdullah M,Hisamuddin M,Ali S,Naqvi IH,Verma HN,Ahmed A,Parveen S

更新日期：2017-01-01 00:00:00

abstract：:Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

journal_title：Intervirology

authors： Kaba M,Moal V,Gérolami R,Colson P

更新日期：2013-01-01 00:00:00

abstract：:We examined influenza virus strains of the subtype H3N2 from outbreaks of respiratory diseases in swine herds in Germany. Four different clusters can be distinguished when comparing parts of the HA1 gene from porcine H3N2 isolates analyzed between 1982 and 2001. Comparison between these clusters reveals a bp homology ...

journal_title：Intervirology

authors： Schrader C,Süss J

更新日期：2004-01-01 00:00:00

abstract：:In this study, we analyzed the in vitro expression, potency and longevity of immune responses induced in a Balb/c mouse model by a synthetic HIV-1 GAG gene exhibiting a codon usage that was adapted to that of highly expressed mammalian genes (syngag). In contrast to a vector containing the wild-type (wt) GAG gene, the...

journal_title：Intervirology

authors： Bojak A,Wild J,Deml L,Wagner R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To clarify the value of contrast-enhanced harmonic ultrasonography (US) with Sonazoid, a second-generation US contrast agent, in the differential diagnosis of liver tumors compared to dynamic CT. METHODS:A total of 249 hepatic nodules in 214 patients were studied; these included 177 hepatocellular carcinomas...

journal_title：Intervirology

authors： Hatanaka K,Kudo M,Minami Y,Ueda T,Tatsumi C,Kitai S,Takahashi S,Inoue T,Hagiwara S,Chung H,Ueshima K,Maekawa K

更新日期：2008-01-01 00:00:00

abstract：:Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antige...

journal_title：Intervirology

authors： Norrild B,Vestergaard BF

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:The potential risk of accidental infection by hantaviruses in a clinical or research laboratory necessitates special precautionary measures. A biosafety program must address handling and disposal of infectious materials as well as appropriate virus inactivation or depletion procedures to permit necessary fur...

journal_title：Intervirology

authors： Kraus AA,Priemer C,Heider H,Kruger DH,Ulrich R

更新日期：2005-01-01 00:00:00

abstract：:Human cytomegalovirus (CMV) has devised numerous means of escaping immune surveillance. The CMV genome encodes at least 4 genes involved in downregulating surface expression of HLA class I molecules. In addition, it sequesters CC chemokines, induces Fc receptors, interferes with induction of HLA class II antigens, and...

journal_title：Intervirology

authors： Michelson S

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Cervical cancer is the third most common malignancy in females. Since the human papillomavirus (HPV) genotype can vary geographically, it is essential to define its genotypic distribution before establishing health care policies and vaccination programs in any given area. The aim of this study was to determin...

journal_title：Intervirology

authors： Taghizadeh E,Taheri F,Abdolkarimi H,Ghorbani Renani P,Gheibi Hayat SM

更新日期：2017-01-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) genetic diversity is one of the most important features of HIV-1 infections and the result of error accumulation during reverse transcription and of high viral turnover. HIV-1 reverse transcription is influenced by factors such as the level of nucleotides and/or the cellular...

journal_title：Intervirology

authors： Russo CT,Alkmim W,Munerato P,Zukurov J,Maricato JT,Sucupira MC,Diaz RS,Janini LM

更新日期：2014-01-01 00:00:00

abstract：:The actinomycin-D(AMD)-sensitive step of replication of three plant viruses - cowpea chlorotic mottle virus (CCMV), cowpea mosaic virus, and the cowpea strain of tobacco mosaic virus - in cowpea was specific for each virus. Different combinations of the viruses were examined in which leaves were inoculated with one vi...

journal_title：Intervirology

authors： Turner MS,Dawson WO

更新日期：1984-01-01 00:00:00

abstract：:The complete nucleotide sequence of rice dwarf phytoreovirus genome segment 2 (S2) was determined to be 3,512 nucleotides long with one open reading frame initiating at nucleotide 15 and terminating at nucleotide 3363. The encoded polypeptide was predicted to have 1,116 residues with a relative molecular weight of 123...

journal_title：Intervirology

authors： Uyeda I,Suda N,Yamada N,Kudo H,Murao K,Suga H,Kimura I,Shikata E,Kitagawa Y,Kusano T

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:Sandfly fever phleboviruses are endemic in Mediterranean countries. We report a febrile phlebovirus case in a Greek patient who presented signs of neuroinvasive infection. METHODS:In summer 2010, a 20-year-old male was admitted to hospital with fever and lethargy; he was a resident of central Macedonia, nort...

journal_title：Intervirology

authors： Papa A,Mallias J,Tsergouli K,Markou F,Poulou A,Milidis T

更新日期：2014-01-01 00:00:00

abstract：:CMV-transformed cell lines demonstrated a greater level of H-ras RNA (7.5- to 9.5-fold) relative to the level for H-ras in parental cells. Nuclear run off assays showed that the RNA levels for the H-ras gene were regulated at the level of transcriptional initiation. The increased RNA levels for H-ras correlated with t...

journal_title：Intervirology

authors： Boldogh I,Huang ES,Rady P,Arany I,Tyring S,Albrecht T

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Dengue virus is spread in tropical areas of the world and is the causative agent of dengue fever and dengue hemorrhagic fever. It is horizontally transmitted to humans by infected Aedes mosquitoes, but it is also able to be vertically or transovarially transmitted to insect progeny. OBJECTIVE:In this work, ...

journal_title：Intervirology

authors： Günther J,Martínez-Muñoz JP,Pérez-Ishiwara DG,Salas-Benito J

更新日期：2007-01-01 00:00:00

abstract：:In this study, 574 stool samples from children with gastroenteritis were obtained from different hospitals in Costa Rica, Honduras, Nicaragua and the Dominican Republic during 2005-2006. Diarrhea stool samples were analyzed for rotavirus by ELISA and typed by the RT-PCR-based method. Unusual strains were detected: G1P...

journal_title：Intervirology

authors： Bourdett-Stanziola L,Ortega-Barria E,Espinoza F,Bucardo F,Jimenez C,Ferrera A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Transmission of many viruses occurs by direct transmission during a close contact between two hosts, or by an indirect transmission through the environment. Several and often interconnected factors, both abiotic and biotic, determine the persistence of these viruses released in the environment, which can las...

journal_title：Intervirology

authors： Labadie T,Batéjat C,Leclercq I,Manuguerra JC

更新日期：2020-01-01 00:00:00

abstract：:Healthy common marmosets from two separate colonies, one in England and one in France, were found to have antibodies cross-reacting with Epstein-Barr virus structural antigens (EBV-VCA). All seropositive animals were at least 2 years old. Experimental EBV infection of marmosets of different ages led to seroconversion ...

journal_title：Intervirology

authors： de-Thé G,Dubouch P,Fontaine C,Wedderburn N,Carter RL,Edwards MB,Cohen B

更新日期：1980-01-01 00:00:00

abstract：:Rauscher murine leukemia virus (RLV) infection of adult mice results in splenomegaly that is proportional to the virus titer. We have used this model to study the therapy of chronic viremia as well as chemoprophylaxis after viral exposure, both with single agents and with combination therapy. We showed that prompt ini...

journal_title：Intervirology

authors： Ruprecht RM

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Infection with tick-borne encephalitis virus (TBEV) causes pathological changes in the central nervous system. However, the possible redox alterations in the infected cells that can contribute to the virus pathogenicity remain unknown. OBJECTIVE:In the current study we explored the ability of TBEV nonstruct...

journal_title：Intervirology

authors： Kuzmenko YV,Smirnova OA,Ivanov AV,Starodubova ES,Karpov VL

更新日期：2016-01-01 00:00:00

abstract：:6/94 virus, isolated originally from a multiple sclerosis (MS) patient, was compared antigenically with related parainfluenza type 1 strains. These included two Sendai strains of mouse and two Sendai strains of reported human origin as well as the HA2 strain. By standard hemagglutination inhibition (HI) or hemadsorpti...

journal_title：Intervirology

authors： Lief FS,Loh W,Meulen VT,Koprowski H

更新日期：1975-01-01 00:00:00

abstract：:9-beta-D-Arabinofuranosyladenine (ara A) was shown to inhibit a specific step of tobacco mosaic virus (TMV) multiplication. The time course of the ara A-sensitive function occurred 'late' coinciding with the period of viral RNA and protein synthesis. When treatment began after viral RNA synthesis was established, 1.0 ...

journal_title：Intervirology

authors： Dawson WO,Lozoya-Saldana H

更新日期：1986-01-01 00:00:00

abstract：:Acute hemorrhagic conjunctivitis (AHC) virus strains isolated in eight different areas during epidemics of AHC were tested for the reproductive capacity at 33, 37 and 39 degrees. All of the 25 strains tested grew better at 33 degrees but restrictively at 39 degrees. The degree of temperature sensitivity varied slightl...

journal_title：Intervirology

authors： Miyamura K,Sasagawa A,Tajiri E,Kono R

更新日期：1976-01-01 00:00:00