Rotavirus genotypes in Costa Rica, Nicaragua, Honduras and the Dominican Republic.

abstract：OBJECTIVE:To determine whether liver-derived hepatitis C RNA-containing particles express the E1E2 discontinuous antigenic determinant defined by unique monoclonal antibody (mAb) D32.10 which recognizes three highly conserved segments in E1 (aa297-306) and E2 (aa480-494 and aa613-621) envelope glycoproteins. METHODS:H...

journal_title：Intervirology

authors： Ndongo N,Selliah S,Berthillon P,Raymond VA,Trépo C,Bilodeau M,Petit MA

更新日期：2011-01-01 00:00:00

abstract：:Acute hemorrhagic conjunctivitis (AHC) virus strains isolated in eight different areas during epidemics of AHC were tested for the reproductive capacity at 33, 37 and 39 degrees. All of the 25 strains tested grew better at 33 degrees but restrictively at 39 degrees. The degree of temperature sensitivity varied slightl...

journal_title：Intervirology

authors： Miyamura K,Sasagawa A,Tajiri E,Kono R

更新日期：1976-01-01 00:00:00

abstract：:Purified Junin virus was disrupted by nonionic detergent treatment (Triton X-100), and subviral components were separated by ultracentrifugation. Only the soluble fraction, containing all of the major glycoprotein (mol.wt. 38,000), induced the formation of neutralizing antibodies in laboratory animals and protected th...

journal_title：Intervirology

authors： Cresta B,Padula P,de Martinez Segovia M

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVES:Data on drug-resistant mutations (DRMs) in HIV-1-infected therapy-naïve children are scarce. The aim of this study was to determine the HIV-1 subtype distribution and the prevalence of DRMs in therapy-naïve HIV-1-infected children who received routine care at the University Hospital Düsseldorf, Düsseldorf, G...

journal_title：Intervirology

authors： Neubert J,Michalsky N,Laws HJ,Borkhardt A,Jensen B,Lübke N

更新日期：2016-01-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) genetic diversity is one of the most important features of HIV-1 infections and the result of error accumulation during reverse transcription and of high viral turnover. HIV-1 reverse transcription is influenced by factors such as the level of nucleotides and/or the cellular...

journal_title：Intervirology

authors： Russo CT,Alkmim W,Munerato P,Zukurov J,Maricato JT,Sucupira MC,Diaz RS,Janini LM

更新日期：2014-01-01 00:00:00

abstract：:Virus-associated DNA polymerase activity has recently been proposed for the detection of human cytomegalovirus (HCMV) in urine, a method that should allow rapid and quantitative determination of the viral load. In this report, the virus-associated DNA polymerase activity recovered from the urine of a group of patients...

journal_title：Intervirology

authors： Marcello A,Pisoni G,Pizzighella S,Palù G

更新日期：1996-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV), like all herpesviruses, persists in the host after primary infection, with reactivation often occurring as a result of immunosuppression. The lack of a model system has made analysis of HCMV latency and reactivation difficult. However, the ability to analyse which specific cell types in v...

journal_title：Intervirology

authors： Sinclair J,Sissons P

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To study the anti-herpes simplex virus (HSV) activity of a (1→6)-(1→3)-β-D-glucan isolated from Agaricus brasiliensis fruiting bodies (FR) as well as its chemically sulfated derivative (FR-S). METHODS:The antiherpetic activity and mechanism of action was studied by viral plaque assay applying different metho...

journal_title：Intervirology

authors： Cardozo FT,Camelini CM,Leal PC,Kratz JM,Nunes RJ,Mendonça MM,Simões CM

更新日期：2014-01-01 00:00:00

abstract：:Acyclovir inhibits herpes simplex virus (HSV) infections better in human fibroblasts than in green monkey kidney cells. Thymidine and acyclovir compete for the active site of HSV thymidine kinase. Large intracellular pools of thymidine found by high-performance liquid chromatography (HPLC) seemed to be responsible for...

journal_title：Intervirology

authors： Harmenberg J

更新日期：1983-01-01 00:00:00

abstract：:The ability to discriminate between herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) infections by serological means is of increasing importance for clinical virological diagnostics. HSV type-specific serology has a number of applications, e.g. to guide duration and dosage of antiviral therapy, to allow for string...

journal_title：Intervirology

authors： Bergström T,Trybala E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Infection with tick-borne encephalitis virus (TBEV) causes pathological changes in the central nervous system. However, the possible redox alterations in the infected cells that can contribute to the virus pathogenicity remain unknown. OBJECTIVE:In the current study we explored the ability of TBEV nonstruct...

journal_title：Intervirology

authors： Kuzmenko YV,Smirnova OA,Ivanov AV,Starodubova ES,Karpov VL

更新日期：2016-01-01 00:00:00

abstract：:The amino acid composition (AAC) of the coat proteins (CPs) of 126 plant viruses or strains were analyzed by stepwise discriminant analysis. The criteria chosen for discrimination were: the structure of virus particles (3 clusters); the mode of of transmission of the viruses (6 clusters); and the grouping of viruses a...

journal_title：Intervirology

authors： Fauquet C,Dejardin J,Thouvenel JC

更新日期：1986-01-01 00:00:00

abstract：:Plants mixedly infected with the U2 strain of tobacco mosaic virus (T2MV) and sunnhemp mosaic virus (SHMV) and grown at 35 degrees, yield particles of the same modal lengths (300 and 40 nm) as those found in plants singly infected with SHMV, but not in plants infected with T2MV, which yield only the long particles. At...

journal_title：Intervirology

authors： Skotnicki A,Gibbs A,Shaw DC

更新日期：1976-01-01 00:00:00

abstract：:Examination of newborn mice, inoculated intraperitoneally with high doses of scrapie virus, revealed that the virus could not be reisolated from their tissues after about 1 week following inoculation, until almost 1 year later. The inoculum was rapidly removed and was not detectable, although the animals became latent...

journal_title：Intervirology

authors： Hotchin J,Sikora E,Baker F

更新日期：1983-01-01 00:00:00

abstract：:Genital infection with high-risk human papillomaviruses (HPV) has been etiologically linked with the development of cervical and other anogenital cancers. There is therefore a need for an effective HPV vaccine with the potential to significantly reduce the burden of more than half a million new cervical cancer cases i...

journal_title：Intervirology

authors： Kirnbauer R

更新日期：1996-01-01 00:00:00

abstract：:By 48 h postinfection, 40--80% of SV40-infected CV-1 cells have undergone irreversible injury as indicated by trypan blue staining. Nevertheless, at this time the lysosomes of these cells appear as discrete structures after vital staining with either acridine orange or neutral red. Lysosomes, vitally stained with neut...

journal_title：Intervirology

authors： Einck KH,Norkin LC

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adsorption and kinetic parameters, latent period, burst size and burst time, are characteristics of phage/host systems and can be affected by several environmental factors. As only few studies have focused on temperate dairy phages, we characterized these parameters on temperate Lactobacillus paracasei ...

journal_title：Intervirology

authors： Mercanti DJ,Ackermann HW,Quiberoni A

更新日期：2015-01-01 00:00:00

abstract：:We investigated persistent infection of Epstein-Barr virus (EBV)-transformed lymphoblastoid cells with dengue virus using a transmission electron microscope. Most of the infected cells kept an intact morphology with only a few virus particles in the cytoplasm, but without any indication of active viral replication. So...

journal_title：Intervirology

authors： Takasaki T,Takada K,Kurane I

更新日期：2001-01-01 00:00:00

abstract：:Studies of human papillomavirus (HPV) infection are hampered by the lack of an adequate culture system. The athymic mouse xenograft system permits propagation of HPV, but only a few HPV types have been grown in this manner. To produce an oncogenic type for studies of HPV pathogenesis, a condylomata acuminata lesion fr...

journal_title：Intervirology

authors： Bryan JT,Tekchandani J,Schroeder JM,Brown DR

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:To express E1 glycoprotein of rubella virus (RuV) strain JR23 in yeast and develop a diagnostic assay using expressed E1 protein as coating antigen in comparison with other diagnostic assays. METHODS:cDNA of E1 open reading frame of RuV was PCR amplified using plasmid pMD18-T-E1 as template and cloned into ...

journal_title：Intervirology

authors： Wen H,Wang Z

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:The potential risk of accidental infection by hantaviruses in a clinical or research laboratory necessitates special precautionary measures. A biosafety program must address handling and disposal of infectious materials as well as appropriate virus inactivation or depletion procedures to permit necessary fur...

journal_title：Intervirology

authors： Kraus AA,Priemer C,Heider H,Kruger DH,Ulrich R

更新日期：2005-01-01 00:00:00

abstract：:In this article, a statistical score method for comparison of partial genomic regions in their representatives of full-length genome of hepatitis E virus (HEV) for genotyping was developed. The critical values of the statistics for hypothesis testing were generated through Monte Carlo simulations. It was found that fr...

journal_title：Intervirology

authors： Xun P,Chen F,Dong C,Qian G,Lai D,Meng J

更新日期：2007-01-01 00:00:00

abstract：:Serial passage of undiluted herpes simplex virus types 1 and 2 resulted in cyclic production of infectious and defective virions. Defective virus production was characterized by the appearance of a new species of viral DNA with a higher bouyant density in CsCl than standard viral DNA. Measurement of the infectivity ti...

journal_title：Intervirology

authors： Murray BK,Biswal N,Bookout JB,Lanford RE,Courtney RJ,Melnick JL

更新日期：1975-01-01 00:00:00

abstract：AIMS:The aim of the present study is the preliminary characterization of an El Tor vibriophage M4 (ATCC 51352-B4). METHODS:We studied the growth characteristics and sustainability of this phage under various stresses like temperature, pH, and UV. The phage morphology and phage genome were also examined using electron ...

journal_title：Intervirology

authors： Das S,Ghosh AN

更新日期：2017-01-01 00:00:00

abstract：:Despite decades of research, no aetiologic factor(s) for human breast cancer has been identified and the search for a causal agent has all but been abandoned during the past thirty years. Over 60 years ago, it was demonstrated that breast tumours in mice are caused by an oncornavirus, murine mammary tumour virus (MMTV...

journal_title：Intervirology

authors： Mant C,Hodgson S,Hobday R,D'Arrigo C,Cason J

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:In this study we established a mouse brain injection system to detect infectious dengue-2 virus produced from the full-length RNA transcripts. METHODS:In vitro transcription was used to synthesize full-length dengue-2 virus RNA from the plasmid pRS424FLDEN2NGC, which was intracerebrally injected into the 6-d...

journal_title：Intervirology

authors： Lee YR,Huang KJ,Lei HY,Chen SH,Lin YS,Yeh TM,Liu HS

更新日期：2005-01-01 00:00:00

abstract：:We examined the effect of infection by other herpesviruses on the induction of Epstein-Barr virus (EBV) antigens. Raji cells were infected with a variety of viruses before superinfection with P3HR-1 virus 6 h later. Much earlier and greater synthesis of EBV antigens was observed in herpesvirus (herpes simplex virus ty...

journal_title：Intervirology

authors： Kikuta H,Rapp F

更新日期：1988-01-01 00:00:00

abstract：:A SmaI map of class I defective DNA of herpes simplex virus type 1 (HSV1) was constructed using a set of deletion hybrid phages. Four SmaI fragments on the defective DNA had a variability in length common among 15 HSV1 isolates: the 1.45 kilobase (kb) fragment located within the BamHI-Z (map coordinates 0.936-0.949) f...

journal_title：Intervirology

authors： Umene K

更新日期：1985-01-01 00:00:00

abstract：:Marituba virus was purified by rate-zonal sedimentation and equilibrium density centrifugation in sucrose gradients. The buoyant density of virus particles was 1.19 g/ml. Purified virus was dissociated and its proteins were analyzed by SDS-PAGE. Four virus polypeptides were identified and designated L, G1, G2 and N. T...

journal_title：Intervirology

authors： Frugulhetti IC,Soares MC,Rebello MA

更新日期：1983-01-01 00:00:00

abstract：:We examined influenza virus strains of the subtype H3N2 from outbreaks of respiratory diseases in swine herds in Germany. Four different clusters can be distinguished when comparing parts of the HA1 gene from porcine H3N2 isolates analyzed between 1982 and 2001. Comparison between these clusters reveals a bp homology ...

journal_title：Intervirology

authors： Schrader C,Süss J

更新日期：2004-01-01 00:00:00