Preliminary Characterization of El Tor Vibriophage M4.

abstract：BACKGROUND:Herpesviridae encode a family of protein homologues that function as the 'port of entry' for insertion of the viral DNA into preformed capsids during encapsidation. METHODS:Transmission electron microscopy (TEM) of recombinant varicella-zoster virus pORF54 was performed. RESULTS:Results suggest that pORF54...

journal_title：Intervirology

authors： Visalli RJ,Howard AJ

更新日期：2014-01-01 00:00:00

abstract：:Infection with hepatitis B virus (HBV) continues to be a major problem in the human population. There remains a specific requirement for HBV vaccines capable of circumventing the non-responder/inadequate responder status of some vaccinees. Hepacare has been primarily developed to (1) improve anti-SHBs antibody titres ...

journal_title：Intervirology

authors： Page M,Jones CD,Bailey C

更新日期：2001-01-01 00:00:00

abstract：:Despite frequent statements to the contrary, there are good animal models for AIDS. In this review, we summarize the properties of one of the most useful animal models: infection of rhesus monkeys with simian immunodeficiency virus (SIV). The SIVs are an extensive group of HIV-related lentiviruses of nonhuman primates...

journal_title：Intervirology

authors： Desrosiers RC,Ringler DJ

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the mutational patterns on the pol gene of the main HIV-1 strain archived in cell genome of 10 chronically infected men according to their clinical and therapeutic history. The genotyping resistance profiles were compared between the first blood plasma available at the time of HIV diagnosis and re...

journal_title：Intervirology

authors： Depincé AE,Dussert E,Vergnon-Miszczycha D,Keita A,Pillet S,Botelho-Nevers E,Frésard A,Gagneux-Brunon A,Lucht FR,Roblin X,Pozzetto B,Paul S,Bourlet T

更新日期：2016-01-01 00:00:00

abstract：:The use of glutaraldehyde (GA)-treated chicken red blood cells (RBC) for purification of Sendai virions by adsorption and elution was found to be advantageous over the use of untreated RBC. Biologic and enzymatic activities and structural components of the purified virions were compared with those of the original viri...

journal_title：Intervirology

authors： Hosaka Y,Hosokawa Y

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVES:To investigate the prevalence of hepatitis E virus (HEV) among patients with chronic hepatitis B and chronic hepatitis C, serum samples were collected between January and December 2004 from patients with chronic hepatitis B and chronic hepatitis C. METHODS:There were 190 adult patients with chronic hepatiti...

journal_title：Intervirology

authors： Bayram A,Eksi F,Mehli M,Sözen E

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:In this study we established a mouse brain injection system to detect infectious dengue-2 virus produced from the full-length RNA transcripts. METHODS:In vitro transcription was used to synthesize full-length dengue-2 virus RNA from the plasmid pRS424FLDEN2NGC, which was intracerebrally injected into the 6-d...

journal_title：Intervirology

authors： Lee YR,Huang KJ,Lei HY,Chen SH,Lin YS,Yeh TM,Liu HS

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to investigate the molecular mechanism of hepatocellular carcinoma (HCC) development induced by hepatitis B virus X protein (HBx). METHODS:We previously established a H7402-X cell line that constitutively expresses HBx protein. In the present study, H7402-X gene expression profiles a...

journal_title：Intervirology

authors： Ye L,Dong N,Wang Q,Xu Z,Cai N,Wang H,Zhang X

更新日期：2008-01-01 00:00:00

abstract：:Despite the significant medical advances which have taken place in the last decades, acute diarrhoea cases remain a public health issue of major significance, with gastroenteritis agents being associated with severe symptoms in adults and high morbidity in infants and children. Regarding rotaviruses, while children ar...

journal_title：Intervirology

authors： Vontas A,Hadjicristodoulou C,Krikelis V,Petinaki E

更新日期：2019-01-01 00:00:00

abstract：:Biochemical studies on human coronavirus, strain 229E, indicate that the RNA is present in the virion in association with protein as a ribonucleoprotein (RNP) complex. Morphological studies have revealed that this nucleocapsid is probably a continuous helical RNP. ...

journal_title：Intervirology

authors： Kennedy DA,Johnson-Lussenburg CM

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adsorption and kinetic parameters, latent period, burst size and burst time, are characteristics of phage/host systems and can be affected by several environmental factors. As only few studies have focused on temperate dairy phages, we characterized these parameters on temperate Lactobacillus paracasei ...

journal_title：Intervirology

authors： Mercanti DJ,Ackermann HW,Quiberoni A

更新日期：2015-01-01 00:00:00

abstract：:Solubilized envelope antigens (glycoproteins) of Sendai virus were purified in a DEAE-Bio-Gel A column. Monospecific antisera were prepared against the antigens, designated HN and F glycoproteins. These glycoproteins are antigenically distinct. Immunodiffusion analyses of the envelope antigens of three representative ...

journal_title：Intervirology

authors： Urata DM,Seto JT

更新日期：1975-01-01 00:00:00

abstract：:In a synchronous infection of cowpea chlorotic mottle virus in cowpea leaves, the three largest viral RNA components were synthesized throughout the infection at relatively constant ratios of two molecules of component 3 to one each of components 1 and 2. Component 4 (the coat protein message) was produced minimally d...

journal_title：Intervirology

authors： Dawson WO

更新日期：1978-01-01 00:00:00

abstract：:Human skin fibroblasts have previously been reported to display an age-dependent resistance to infection with coxsackie B4 virus. We have shown that the virus will replicate and produce CPE in human skin fibroblasts regardless of the age of the donor of the cells. The passage history of the virus was found to influenc...

journal_title：Intervirology

authors： Miller M,Harnett GB,Bucens MR

更新日期：1988-01-01 00:00:00

abstract：:Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

journal_title：Intervirology

authors： Kaba M,Moal V,Gérolami R,Colson P

更新日期：2013-01-01 00:00:00

abstract：:An open-reading frame designated 1R1, on DNA component 1 of bean golden mosaic geminivirus (BGMV), has been identified as the coat protein gene. A DraI restriction fragment of BGMV DNA1 that includes 1R1 was inserted into the SmaI pKK223-3 expression vector. The 32 kD protein expressed in Escherichia coli cells reacte...

journal_title：Intervirology

authors： Murayama A,Yamaya Y,Ikegami M

更新日期：1991-01-01 00:00:00

abstract：:Examination of the effect of 2-thiouracil on tobacco mosaic virus (TMV) RNA and protein synthesis in synchronous and asynchronous systems of replication in tobacco leaves demonstrated that 2-thiouracil does not prevent synthesis of TMV RNA, as suggested by previous studies, but inhibits some earlier function. When add...

journal_title：Intervirology

authors： Dawson WO,Grantham GL

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:Human Salivirus (SalV) has been associated with gastroenteritis on all continents. METHODS:This paper presents the real-time RT-PCR assay for the detection of SalV in clinical fecal samples collected from 192 hospitalized children with acute gastroenteritis in Piedmont, Italy. RESULTS:The most commonly dete...

journal_title：Intervirology

authors： Bergallo M,Daprà V,Rassu M,Bonamin S,Cuccu R,Calvi C,Montanari P,Galliano I

更新日期：2018-01-01 00:00:00

abstract：:Human skin fibroblasts were previously shown to be resistant to coxsackie B4 virus infection. We have cultured fibroblasts from skin and lung tissues of donors of various ages. By a novel method for direct assay of virus absorption and penetration, we have shown that skin fibroblasts from young fetuses are susceptible...

journal_title：Intervirology

authors： Hornberger E,Plotkin SA

更新日期：1983-01-01 00:00:00

abstract：:Immunopathologic mechanisms leading to liver tissue injury in hepatitis caused by hepatitis A virus (HAV) were studied in an autologous in vitro model. Data show virus-specific killing by liver-infiltrating T lymphocytes in man and support the hypothesis that hepatocellular damage as well as efficient elimination of v...

journal_title：Intervirology

authors： Vallbracht A,Fleischer B,Busch FW

更新日期：1993-01-01 00:00:00

abstract：:3 mM n-butyrate, which effectively induces synthesis of Epstein-Barr virus (EBV) antigens in the producer P3HR-1 cell line, inhibited the transformation of umbilical cord blood lymphocytes by EBV. The drug inhibited both EBNA synthesis and stimulation of host cell DNA synthesis by strain B95-8. This effect was less pr...

journal_title：Intervirology

authors： Roubalová K,Roubal J

更新日期：1985-01-01 00:00:00

abstract：:Scrapie brain homogenate was mixed with mouse peritoneal macrophages in vitro. After 2 h of incubation at 37 degrees, a portion of the scrapie infectivity was associated with macrophages. In contrast, very little infectivity was associated with kidney cells that had been exposed to scrapie brain homogenate. After incu...

journal_title：Intervirology

authors： Carp RI,Callahan SM

更新日期：1981-01-01 00:00:00

abstract：:Transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are similar coronaviruses, causing diseases characterized by vomiting, diarrhea, and death from severe dehydration in piglets. Thus, they have caused huge losses to the swine-breeding industry worldwide. Nowadays, they are easily tra...

journal_title：Intervirology

authors： Yuan P,Yang Z,Song H,Wang K,Yang Y,Xie L,Huang S,Liu J,Ran L,Song Z

更新日期：2018-01-01 00:00:00

abstract：:Antibodies of individuals infected with the human immunodeficiency virus type 1 (HIV-1) were used to probe the antigenicity of the HIV-1 transmembrane protein of 41 kD (gp41) by antibody-reactive peptide scanning (Pepscan). Eleven distinct sequential antibody-binding sites were defined by testing reactivity to 339 ove...

journal_title：Intervirology

authors： Goudsmit J,Meloen RH,Brasseur R

更新日期：1990-01-01 00:00:00

abstract：:5 patients with primary genital herpes simplex virus (HSV) infection were studied prospectively for the production of serum antibody reactivity as measured by the virus micro-neutralization test (NT), micro-solid phase radioimmunometric assay (micro-SPRIA), and antibody-dependent cellular-cytotoxic (ADCC) test. ADCC a...

journal_title：Intervirology

authors： Kohl S,Adam E,Matson DO,Kaufman RH,Dreesman GR

更新日期：1982-01-01 00:00:00

abstract：:Acyclovir inhibits herpes simplex virus (HSV) infections better in human fibroblasts than in green monkey kidney cells. Thymidine and acyclovir compete for the active site of HSV thymidine kinase. Large intracellular pools of thymidine found by high-performance liquid chromatography (HPLC) seemed to be responsible for...

journal_title：Intervirology

authors： Harmenberg J

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:To study the anti-herpes simplex virus (HSV) activity of a (1→6)-(1→3)-β-D-glucan isolated from Agaricus brasiliensis fruiting bodies (FR) as well as its chemically sulfated derivative (FR-S). METHODS:The antiherpetic activity and mechanism of action was studied by viral plaque assay applying different metho...

journal_title：Intervirology

authors： Cardozo FT,Camelini CM,Leal PC,Kratz JM,Nunes RJ,Mendonça MM,Simões CM

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Sandfly fever phleboviruses are endemic in Mediterranean countries. We report a febrile phlebovirus case in a Greek patient who presented signs of neuroinvasive infection. METHODS:In summer 2010, a 20-year-old male was admitted to hospital with fever and lethargy; he was a resident of central Macedonia, nort...

journal_title：Intervirology

authors： Papa A,Mallias J,Tsergouli K,Markou F,Poulou A,Milidis T

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to determine the hepatitis B virus (HBV) genotypes in hepatitis delta virus (HDV) RNA-positive patients and to characterize the HBV nucleotide sequences that may be found on a distant island of Japan. METHODS:This study included three patients with chronic hepatitis who were posi...

journal_title：Intervirology

authors： Moriyama M,Taira M,Matsumura H,Aoki H,Mikuni M,Kaneko M,Shioda A,Iwaguchi K,Arai S,Ichijima S,Iwasaki H,Tanaka N,Abe K,Arakawa Y

更新日期：2003-01-01 00:00:00

abstract：:Examination of newborn mice, inoculated intraperitoneally with high doses of scrapie virus, revealed that the virus could not be reisolated from their tissues after about 1 week following inoculation, until almost 1 year later. The inoculum was rapidly removed and was not detectable, although the animals became latent...

journal_title：Intervirology

authors： Hotchin J,Sikora E,Baker F

更新日期：1983-01-01 00:00:00