Human cytomegalovirus escape from immune detection.

abstract：:Hepatitis B virus (HBV) core antigen (HBcAg) detected by the peroxidase-antiperoxidase technique was present in the nucleus and cytoplasm of some infected hepatocytes but only in the cytoplasm of other hepatocytes. When cells expressing HBcAg were examined by in situ hybridization for the presence of HBV DNA, the intr...

journal_title：Intervirology

authors： Gowans EJ,Burrell CJ,Jilbert AR,Marmion BP

更新日期：1985-01-01 00:00:00

abstract：:Human skin fibroblasts have previously been reported to display an age-dependent resistance to infection with coxsackie B4 virus. We have shown that the virus will replicate and produce CPE in human skin fibroblasts regardless of the age of the donor of the cells. The passage history of the virus was found to influenc...

journal_title：Intervirology

authors： Miller M,Harnett GB,Bucens MR

更新日期：1988-01-01 00:00:00

abstract：:An RNA virus was isolated from Trichoplusia ni larvae infected with inoculum of the baculovirus of Autographa californica. Physicochemical characterization has revealed a 35-nm virus with a density in CsCl of 1.3 g/cm3 and a sedimentation coefficient of 200S. The virus consisted of 10--15% single-stranded RNA with an ...

journal_title：Intervirology

authors： Morris TJ,Hess RT,Pinnock DE

更新日期：1979-01-01 00:00:00

abstract：:Marituba virus was purified by rate-zonal sedimentation and equilibrium density centrifugation in sucrose gradients. The buoyant density of virus particles was 1.19 g/ml. Purified virus was dissociated and its proteins were analyzed by SDS-PAGE. Four virus polypeptides were identified and designated L, G1, G2 and N. T...

journal_title：Intervirology

authors： Frugulhetti IC,Soares MC,Rebello MA

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Dengue virus is spread in tropical areas of the world and is the causative agent of dengue fever and dengue hemorrhagic fever. It is horizontally transmitted to humans by infected Aedes mosquitoes, but it is also able to be vertically or transovarially transmitted to insect progeny. OBJECTIVE:In this work, ...

journal_title：Intervirology

authors： Günther J,Martínez-Muñoz JP,Pérez-Ishiwara DG,Salas-Benito J

更新日期：2007-01-01 00:00:00

abstract：:Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antige...

journal_title：Intervirology

authors： Norrild B,Vestergaard BF

更新日期：1979-01-01 00:00:00

abstract：:Damage and necrosis of hepatocytes in viral hepatitis C is considered to be immune mediated as in hepatitis B. Hepatocellular necrosis accompanies infiltration of lymphocytes and this feature, called necroinflammation, characterizes all types of viral hepatitis and corresponds to the histological expression of hepatit...

journal_title：Intervirology

authors： Uchida T

更新日期：1994-01-01 00:00:00

abstract：:The purpose of our work was to determine if aerosols of Junin virus can infect rhesus macaques and if the disease is the same as that produced by virus inoculated parenterally. The 6 macaques exposed to the virus by aerosol became acutely ill during the 3rd week after exposure, and all died. Three died by day 21, whil...

journal_title：Intervirology

authors： Kenyon RH,McKee KT Jr,Zack PM,Rippy MK,Vogel AP,York C,Meegan J,Crabbs C,Peters CJ

更新日期：1992-01-01 00:00:00

abstract：:The use of bleach (hypochlorite) as a disinfectant for drug injection equipment in the intravenous-drug-using population was recommended early in the HIV-1/AIDS epidemic. Epidemiological studies have challenged the use of bleach as an effective measure to prevent HIV-1 transmission. However, in vitro HIV-1 coculture s...

journal_title：Intervirology

authors： Contoreggi C,Jones S,Simpson P,Lange WR,Meyer WA 3rd

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Cervical cancer is the third most common malignancy in females. Since the human papillomavirus (HPV) genotype can vary geographically, it is essential to define its genotypic distribution before establishing health care policies and vaccination programs in any given area. The aim of this study was to determin...

journal_title：Intervirology

authors： Taghizadeh E,Taheri F,Abdolkarimi H,Ghorbani Renani P,Gheibi Hayat SM

更新日期：2017-01-01 00:00:00

abstract：:Despite decades of research, no aetiologic factor(s) for human breast cancer has been identified and the search for a causal agent has all but been abandoned during the past thirty years. Over 60 years ago, it was demonstrated that breast tumours in mice are caused by an oncornavirus, murine mammary tumour virus (MMTV...

journal_title：Intervirology

authors： Mant C,Hodgson S,Hobday R,D'Arrigo C,Cason J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Human respiratory syncytial virus (RSV) infection in infancy and early childhood causes acute bronchiolitis and exacerbates bronchial asthma. Eosinophil infiltration may contribute to airway obstruction in RSV infection. OBJECTIVE:We hypothesized that RSV affects eosinophil function. METHODS:Eosinophil act...

journal_title：Intervirology

authors： Tachibana A,Kimura H,Kato M,Nako Y,Kozawa K,Morikawa A

更新日期：2002-01-01 00:00:00

abstract：:XTrack, a rapid, cost-effective diagnostic HIV tropism system, yields predictive results and dissects virus mixtures. It is based on the duplexing of patient samples with selective DNA probes, combined with sequence-based analysis and replicative phenotyping for ambiguous samples. ...

journal_title：Intervirology

authors： Klimkait T

更新日期：2012-01-01 00:00:00

abstract：:Superinfection of a silently non-A, non-B (NANB)-infected chimpanzee with hepatitis A virus (HAV) resulted in minimal liver enzyme elevations, lack of detectable HAV in stool, and questionable presence of HAV antigen in liver biopsy specimens obtained during the expected period of virus replication. Our findings indic...

journal_title：Intervirology

authors： Bradley DW,Krawczynski K,Humphrey CD,McCaustland KA

更新日期：1987-01-01 00:00:00

abstract：:Analysis of translation products synthesized in vitro in the presence of a mixture of brome mosaic virus (BMV) RNAs 1, 2, 3, and 4 usually shows a predominance of coat protein, coded by RNA4. The proportion of products directed by RNAs 1 and 2 decreased at saturating concentrations of BMV RNA and in the presence of 7-...

journal_title：Intervirology

authors： Pyne JW,Hall TC

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND/AIMS:Adsorption and kinetic parameters, latent period, burst size and burst time, are characteristics of phage/host systems and can be affected by several environmental factors. As only few studies have focused on temperate dairy phages, we characterized these parameters on temperate Lactobacillus paracasei ...

journal_title：Intervirology

authors： Mercanti DJ,Ackermann HW,Quiberoni A

更新日期：2015-01-01 00:00:00

abstract：:SDS-polyacrylamide slab gel analysis of selected primate and nonprimate adenoviruses has shown these viruses to differ significantly at the polypeptide molecular level. It follows that data derived from study of a single adenovirus serotype are unique to that serotype and are not representative of the adenovirus group...

journal_title：Intervirology

authors： Marusyk RG,Cummings GT

更新日期：1978-01-01 00:00:00

abstract：:Virus-associated DNA polymerase activity has recently been proposed for the detection of human cytomegalovirus (HCMV) in urine, a method that should allow rapid and quantitative determination of the viral load. In this report, the virus-associated DNA polymerase activity recovered from the urine of a group of patients...

journal_title：Intervirology

authors： Marcello A,Pisoni G,Pizzighella S,Palù G

更新日期：1996-01-01 00:00:00

abstract：:Membrane particles possessing receptor activity for influenza virions have been reconstituted following solubilization of human erythrocyte membranes with octylglucoside (OG) and fractionation on a DEAE-cellulose column. Fractions that eluted with 1.5 M NaCl yielded, after removal of OG, reconstituted membrane particl...

journal_title：Intervirology

authors： Baron CB,Blough HA

更新日期：1983-01-01 00:00:00

abstract：:The ability to discriminate between herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) infections by serological means is of increasing importance for clinical virological diagnostics. HSV type-specific serology has a number of applications, e.g. to guide duration and dosage of antiviral therapy, to allow for string...

journal_title：Intervirology

authors： Bergström T,Trybala E

更新日期：1996-01-01 00:00:00

abstract：:In this study, 574 stool samples from children with gastroenteritis were obtained from different hospitals in Costa Rica, Honduras, Nicaragua and the Dominican Republic during 2005-2006. Diarrhea stool samples were analyzed for rotavirus by ELISA and typed by the RT-PCR-based method. Unusual strains were detected: G1P...

journal_title：Intervirology

authors： Bourdett-Stanziola L,Ortega-Barria E,Espinoza F,Bucardo F,Jimenez C,Ferrera A

更新日期：2010-01-01 00:00:00

abstract：:The aligned restriction endonuclease maps of three sequenced maize streak virus isolates, three restriction-mapped southern African maize streak virus isolates, and two other sequenced geminiviruses were used as a means of calculating the sequence divergence between these viruses. The degree of divergence was used to ...

journal_title：Intervirology

authors： Kirby R,Clarke BA,Rybicki EP

更新日期：1989-01-01 00:00:00

abstract：:Genital infection with high-risk human papillomaviruses (HPV) has been etiologically linked with the development of cervical and other anogenital cancers. There is therefore a need for an effective HPV vaccine with the potential to significantly reduce the burden of more than half a million new cervical cancer cases i...

journal_title：Intervirology

authors： Kirnbauer R

更新日期：1996-01-01 00:00:00

abstract：:A reverse transcriptase, polymerase chain reaction (RT-PCR) procedure was used to amplify a segment of the genome of turkey coronavirus (TCV) spanning portions of the matrix and nucleocapsid (MN) protein genes (approximately 1.1 kb). The MN gene region of three epidemiologically distinct TCV strains (Minnesota, NC95, ...

journal_title：Intervirology

authors： Breslin JJ,Smith LG,Fuller FJ,Guy JS

更新日期：1999-01-01 00:00:00

abstract：:Bovine adenoviruses (BAVs) are important pathogens causing significant economic losses to the cattle industry. We have been interested in the differences among serotypes of these viruses, particularly in their pathogenicity and host range. As part of our efforts to better understand these viruses, we have determined t...

journal_title：Intervirology

authors： Yagubi A,Ojkic D,Bautista DS,Haj-Ahmad Y

更新日期：1998-01-01 00:00:00

abstract：:Antibodies of individuals infected with the human immunodeficiency virus type 1 (HIV-1) were used to probe the antigenicity of the HIV-1 transmembrane protein of 41 kD (gp41) by antibody-reactive peptide scanning (Pepscan). Eleven distinct sequential antibody-binding sites were defined by testing reactivity to 339 ove...

journal_title：Intervirology

authors： Goudsmit J,Meloen RH,Brasseur R

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Pandemic viral infections as emerging infectious diseases are of a great global concern. However, for some viruses, particular strains are endemic to specific areas and can be genetically distinguished from strains in other regions. In contrast, for some other viruses, genetically similar strains can spread a...

journal_title：Intervirology

authors： Furuse Y,Suzuki A,Kamigaki T,Mpolya EA,Khandaker I,Oshitani H

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:In the present study, we aimed to determine whether signal-to-cutoff (S/Co) ratios of reactive anti-HCV samples could be used as a basis for avoiding the need for supplemental testing in our study population. METHODS:We analyzed 901 anti-HCV-positive sera from 8 institutions in China. The Ortho VITROS anti-...

journal_title：Intervirology

authors： Zhang K,Wang L,Lin G,Li J

更新日期：2015-01-01 00:00:00

abstract：:3 mM n-butyrate, which effectively induces synthesis of Epstein-Barr virus (EBV) antigens in the producer P3HR-1 cell line, inhibited the transformation of umbilical cord blood lymphocytes by EBV. The drug inhibited both EBNA synthesis and stimulation of host cell DNA synthesis by strain B95-8. This effect was less pr...

journal_title：Intervirology

authors： Roubalová K,Roubal J

更新日期：1985-01-01 00:00:00

abstract：:Coinfections with hepatitis B virus (HBV) and HIV are very frequent. Although HBV is a DNA virus, it replicates via reverse transcription like HIV. Structural similarities between the enzymatic pocket of the HBV DNA polymerase and HIV-1 reverse transcriptase are the basis that certain drugs inhibit both enzymes and th...

journal_title：Intervirology

authors： Gürtler LG

更新日期：2014-01-01 00:00:00