Abstract:
:3 mM n-butyrate, which effectively induces synthesis of Epstein-Barr virus (EBV) antigens in the producer P3HR-1 cell line, inhibited the transformation of umbilical cord blood lymphocytes by EBV. The drug inhibited both EBNA synthesis and stimulation of host cell DNA synthesis by strain B95-8. This effect was less pronounced at lower concentrations, but even at 0.1 mM (which did not affect DNA synthesis in EBNA and stimulation of host cell DNA synthesis in EBV-infected lymphocytes were delayed.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Roubalová K,Roubal Jdoi
10.1159/000149566subject
Has Abstractpub_date
1985-01-01 00:00:00pages
51-4issue
1eissn
0300-5526issn
1423-0100journal_volume
23pub_type
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