High percentage of seronegative HCV infections in hemodialysis patients: the need for PCR.

Abstract:

:Among patients undergoing maintenance hemodialysis, a high prevalence of hepatitis C virus (HCV) infection can be observed. In a prospective study, sera of 273 patients were examined for the presence of HCV infection by serological tests and by PCR. Thirty-five patients (12.8%) were HCV antibody positive, and in 31 of them HCV RNA could be detected by PCR. Among the 238 seronegative patients HCV infection was detected in 12 cases (5.0%) exclusively by PCR. Only in 1 of these patients seroconversion could be observed within the 18-month follow-up period. These findings demonstrate that in hemodialysis patients PCR is necessary for the diagnosis of HCV infection.

journal_name

Intervirology

journal_title

Intervirology

authors

Schröter M,Feucht HH,Schäfer P,Zöllner B,Laufs R

doi

10.1159/000150558

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

277-8

issue

4

eissn

0300-5526

issn

1423-0100

journal_volume

40

pub_type

杂志文章
  • Sequencing analysis of the region encoding the DNA polymerase of bovine adenovirus serotypes 2 and 3.

    abstract::Bovine adenoviruses (BAVs) are important pathogens causing significant economic losses to the cattle industry. We have been interested in the differences among serotypes of these viruses, particularly in their pathogenicity and host range. As part of our efforts to better understand these viruses, we have determined t...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000024917

    authors: Yagubi A,Ojkic D,Bautista DS,Haj-Ahmad Y

    更新日期:1998-01-01 00:00:00

  • Double-filtration plasmapheresis plus IFN for HCV-1b patients with non-sustained virological response to previous combination therapy: early viral dynamics.

    abstract::Double-filtration plasmapheresis (DFPP) was approved in Japan in April 2008 for the retreatment of chronic hepatitis C patients with genotype 1b and high viral loads, whose hepatitis C virus was not eradicated by earlier IFN therapy or by pegylated IFN plus ribavirin (PEG-IFN/RBV) combination therapy. In this study, w...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000252783

    authors: Kim SR,Imoto S,Kudo M,Mita K,Taniguchi M,Kim KI,Sasase N,Shoji I,Nagano-Fujii M,El-Shamy A,Hotta H,Nagai T,Nagata Y,Hayashi Y

    更新日期:2010-01-01 00:00:00

  • Low to medium WU-virus titers in young children with lower respiratory tract infections.

    abstract::The WU-virus (WUV), a novel polyomavirus, has recently been recovered from respiratory tract samples. Within a study collective of children with severe lower respiratory tract disease, 3% of the patients tested WUV positive. Viral loads ranged from 5 x 10(2) copies/ml to 1 x 10(4) copies/ml. The WUV genome-positive pa...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000209673

    authors: Kleines M,Scheithauer S,Hengst M,Honnef D,Ritter K,Mühler E,Häusler M,Rostamzadeh A

    更新日期:2008-01-01 00:00:00

  • Virus Overlay Protein Binding Assay (VOPBA) reveals serotype specific heterogeneity of dengue virus binding proteins on HepG2 human liver cells.

    abstract:OBJECTIVE:This study sought to investigate the presence of dengue virus binding proteins expressed on the surface of HepG2 cells and to determine if there were serotype specific differences in binding. METHODS:HepG2 cell membrane proteins were extracted and separated by SDS-PAGE, transferred to nitrocellulose membrane...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000080882

    authors: Jindadamrongwech S,Smith DR

    更新日期:2004-01-01 00:00:00

  • HIV-2 in rhesus monkeys: serological, virological and clinical results.

    abstract::Diseases induced by animal retroviruses are not considered to be good models for the human acquired immunodeficiency syndrome (AIDS) at present. The lack of an animal model for the human immunodeficiency virus (HIV) infection presents a main problem in the complete understanding of the pathogenesis of HIV-mediated dis...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150125

    authors: Dormont D,Livartowski J,Chamaret S,Guetard D,Henin D,Levagueresse R,van de Moortelle PF,Larke B,Gourmelon P,Vazeux R

    更新日期:1989-01-01 00:00:00

  • Binding of influenza virus to a reconstituted receptor complex containing glycophorin.

    abstract::Membrane particles possessing receptor activity for influenza virions have been reconstituted following solubilization of human erythrocyte membranes with octylglucoside (OG) and fractionation on a DEAE-cellulose column. Fractions that eluted with 1.5 M NaCl yielded, after removal of OG, reconstituted membrane particl...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149334

    authors: Baron CB,Blough HA

    更新日期:1983-01-01 00:00:00

  • Evolutionary relationship of three southern African maize streak virus isolates.

    abstract::The aligned restriction endonuclease maps of three sequenced maize streak virus isolates, three restriction-mapped southern African maize streak virus isolates, and two other sequenced geminiviruses were used as a means of calculating the sequence divergence between these viruses. The degree of divergence was used to ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150080

    authors: Kirby R,Clarke BA,Rybicki EP

    更新日期:1989-01-01 00:00:00

  • Long-term outcome, with monitoring of platelet counts, in patients with chronic hepatitis C and liver cirrhosis after interferon therapy.

    abstract:OBJECTIVE:Because the determination of the stage of fibrosis depends on rather subjective judgment, more objective parameters are needed. In this study, we followed the long-term outcome, with monitoring of platelet counts, in patients with chronic hepatitis C or liver cirrhosis (LC) who had undergone interferon (IFN) ...

    journal_title:Intervirology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000073209

    authors: Moriyama M,Matsumura H,Aoki H,Shimizu T,Nakai K,Saito T,Yamagami H,Shioda A,Kaneko M,Goto I,Tanaka N,Arakawa Y

    更新日期:2003-01-01 00:00:00

  • Glycoproteins of Sendai virus: purification and antigenic analysis.

    abstract::Solubilized envelope antigens (glycoproteins) of Sendai virus were purified in a DEAE-Bio-Gel A column. Monospecific antisera were prepared against the antigens, designated HN and F glycoproteins. These glycoproteins are antigenically distinct. Immunodiffusion analyses of the envelope antigens of three representative ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149462

    authors: Urata DM,Seto JT

    更新日期:1975-01-01 00:00:00

  • Efficient ribosome binding of brome mosaic virus (BMV) RNA4 contributes to its ability to outcompete the other BMV RNAs for translation.

    abstract::Analysis of translation products synthesized in vitro in the presence of a mixture of brome mosaic virus (BMV) RNAs 1, 2, 3, and 4 usually shows a predominance of coat protein, coded by RNA4. The proportion of products directed by RNAs 1 and 2 decreased at saturating concentrations of BMV RNA and in the presence of 7-...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149008

    authors: Pyne JW,Hall TC

    更新日期:1979-01-01 00:00:00

  • Viral Metagenomics Revealed a Novel Cardiovirus in Feces of Wild Rats.

    abstract:BACKGROUND/AIMS:Cardiovirus is a genus of viruses belonging to the family Picornaviridae. Here, we used viral metagenomic techniques to detect the viral nucleic acid in the fecal samples from wild rats in Zhenjiang city in China. METHOD:Fecal samples were collected from 20 wild rats and pooled into four sample pools a...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000500555

    authors: Mahmood A,Shama S,Ni H,Wang H,Ling Y,Xu H,Yang S,Naseer QA,Zhang W

    更新日期:2019-01-01 00:00:00

  • Polyploidization of Epstein-Barr virus (EBV)-carrying lymphoma lines decreases the inducibility of EBV-determined early antigen following P3HR-1 virus superinfection or iododeoxyuridine treatment.

    abstract::Four tetraploid cell lines were derived from the Epstein-Barr virus (EBV)-carrying, nonproducer Burkitt lymphoma line Raji after colcemide treatment. EBV early antigen (EA) was induced by P3HR-1 virus superinfection and by iododeoxyuridine treatment. Inducibility was reduced in all tetraploid lines compared to the nea...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000148973

    authors: Shapiro IM,Andersson-Anvret M,Klein G

    更新日期:1978-01-01 00:00:00

  • Havachoobe (Onosma dichroanthum Boiss) Root Extract Decreases the Hepatitis B Virus Surface Antigen Secretion in the PLC/PRF/5 Cell Line.

    abstract:BACKGROUND:Many efforts are currently focused on functional treatment of the hepatitis B virus (HBV). This can be done by suppressing the secretion of HBV surface antigen (HBsAg). Scientific communities are very interested in natural products in that respect. OBJECTIVE:Use of root extract of Havachoobe (Onosma dichroa...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000512140

    authors: Mohebbi A,Azadi F,Hashemi MM,Askari FS,Razzaghi N

    更新日期:2020-12-15 00:00:00

  • HIV Tat protein increases Bcl-2 expression in monocytes which inhibits monocyte apoptosis induced by tumor necrosis factor-alpha-related apoptosis-induced ligand.

    abstract:OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000100565

    authors: Zheng L,Yang Y,Guocai L,Pauza CD,Salvato MS

    更新日期:2007-01-01 00:00:00

  • Exposure of Piglets to Enteroviruses Investigated by an Immunoassay Based on the EV-G1 VP4 Peptide.

    abstract:OBJECTIVE:The aim of this study was to investigate the exposure of piglets to enteroviruses-G (EV-G) through the presence of antibodies in their serum. METHODS:Serum samples were obtained from the vena cava of 10 piglets at 9 weeks of age and again 39 days later (day 39). They were tested using an immunoassay based on...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000449058

    authors: Benkahla MA,Sane F,Desailloud R,Hober D

    更新日期:2016-01-01 00:00:00

  • A viral aetiology for breast cancer: time to re-examine the postulate.

    abstract::Despite decades of research, no aetiologic factor(s) for human breast cancer has been identified and the search for a causal agent has all but been abandoned during the past thirty years. Over 60 years ago, it was demonstrated that breast tumours in mice are caused by an oncornavirus, murine mammary tumour virus (MMTV...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000076636

    authors: Mant C,Hodgson S,Hobday R,D'Arrigo C,Cason J

    更新日期:2004-01-01 00:00:00

  • Effects of poliovirus replication on undifferentiated and differentiated monocytic U937 cells: comparative studies with human macrophages.

    abstract::Poliovirus infection of either undifferentiated or differentiated U937 cells produced a decrease in the percentage of cells positive for the surface expression of the CD4, CD11c, CD14, or 8E11 antigens. The number of 4F2 surface molecules per cell increased in infected normal U937 cells, but was unaffected in differen...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150194

    authors: López-Guerrero JA,Cabañas C,Bernabeu C,Fresno M,Alonso MA

    更新日期:1991-01-01 00:00:00

  • Special aspects of the treatment of HIV-2-infected patients.

    abstract::HIV-2 is responsible for a limited epidemic in West Africa. Around 20% of all infected patients will progress to AIDS, and will need antiretroviral therapy. Unfortunately, antiretrovirals were developed to suppress HIV-1 replication; not all of them are active against HIV-2, e.g. all nonnucleoside reverse transcriptas...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000332025

    authors: Camacho RJ

    更新日期:2012-01-01 00:00:00

  • Selected amino acid change encoding Epstein-Barr virus-specific T cell epitope of the LMP2A gene in Japanese nasal NK/T cell lymphoma patients.

    abstract::Nasal natural killer (NK)/T cell lymphoma is a peculiar lymphoma with a unique immunophenotype. Etiologically, in 1990, the authors first demonstrated the presence of Epstein-Barr virus (EBV) genomes and their products in this lymphoma. EBV-specific cytotoxic T lymphocytes (CTL) are very important in controlling the l...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000106462

    authors: Nagamine M,Kishibe K,Takahara M,Nagato T,Ishii H,Bandoh N,Ogino T,Harabuchi Y

    更新日期:2007-01-01 00:00:00

  • Identification of the coat protein gene of bean golden mosaic geminivirus.

    abstract::An open-reading frame designated 1R1, on DNA component 1 of bean golden mosaic geminivirus (BGMV), has been identified as the coat protein gene. A DraI restriction fragment of BGMV DNA1 that includes 1R1 was inserted into the SmaI pKK223-3 expression vector. The 32 kD protein expressed in Escherichia coli cells reacte...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150208

    authors: Murayama A,Yamaya Y,Ikegami M

    更新日期:1991-01-01 00:00:00

  • Origin and evolution of eukaryotic large nucleo-cytoplasmic DNA viruses.

    abstract:BACKGROUND/AIMS:The nucleo-cytoplasmic large DNA viruses (NCLDV) constitute an apparently monophyletic group that consists of 6 families of viruses infecting a broad variety of eukaryotes. A comprehensive genome comparison and maximum-likelihood reconstruction of NCLDV evolution reveal a set of approximately 50 conserv...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000312913

    authors: Koonin EV,Yutin N

    更新日期:2010-01-01 00:00:00

  • Sequence Similarities between Viroids and Human MicroRNAs.

    abstract::Viroids are minute unencapsidated non-coding circular RNAs known to be present and to cause diseases only in plants. Infections were associated with the occurrence of specific single-stranded RNAs similar in size to miRNAs and endogenous small interfering RNAs, and viroid pathogenicity is suspected to occur through RN...

    journal_title:Intervirology

    pub_type: 新闻

    doi:10.1159/000509212

    authors: Bengone-Abogourin JG,Chelkha N,Verdin E,Colson P

    更新日期:2019-01-01 00:00:00

  • Barley yellow mosaic virus (BaYMV) and BaYMV-M: two different viruses.

    abstract::Serological and physical properties of isolated particles as well as reactions of barley cultivars after virus inoculation showed that the yellow disease of barley is caused by different viruses. Results summarized in this paper suggest that the European isolates BaYMV-So and BaYMV-NM are closely related to, or identi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150132

    authors: Huth W,Adams MJ

    更新日期:1990-01-01 00:00:00

  • Antigenic differences between HSV-1 and HSV-2 glycoproteins and their importance for type-specific serology.

    abstract::The ability to discriminate between herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) infections by serological means is of increasing importance for clinical virological diagnostics. HSV type-specific serology has a number of applications, e.g. to guide duration and dosage of antiviral therapy, to allow for string...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150493

    authors: Bergström T,Trybala E

    更新日期:1996-01-01 00:00:00

  • Molecular analysis of human influenza virus in Tehran, Iran.

    abstract:BACKGROUND:To date there are no reports of molecular and phylogenetic analyses of human influenza virus in Tehran, Iran. OBJECTIVES:We isolated and characterized circulating influenza viruses in a sample of patients in Tehran. METHODS:Nasal and pharyngeal swabs were collected from 57 individuals who were suspected of...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000214634

    authors: Soltani Z,Hosseini M,Shahidi M,Hedayati M,Kheiri MT

    更新日期:2009-01-01 00:00:00

  • PCR-RFLP-detected human papilloma virus infection in a group of senegalese women attending an STD clinic and identification of a new HPV-68 subtype.

    abstract::Cancer of the cervix is the most common malignant tumor among women in Africa and, in particular, Senegal. Studies of the prevalence of human papilloma virus (HPV) infection in Africa have mainly focused on carcinomas. Data on the presence of the virus in women with normal cervical cytology are scarce. In this study, ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000024981

    authors: Astori G,Beltrame A,Pipan C,Raphenon G,Botta GA

    更新日期:1999-01-01 00:00:00

  • Interleukin-4 is needed for the infection of monocytes by human cytomegalovirus.

    abstract:OBJECTIVE:We studied the ability of human cytomegalovirus (HCMV) to infect peripheral blood mononuclear cells (PBMC) pretreated with or without Th2-cytokine interleukin-4 (IL-4) in vitro. METHODS:Adherent cells and nonadherent cells were obtained from PBMC. We inoculated these cells with HCMV at concentrations ranging...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000050057

    authors: Kitajima H,Okubo Y,Honda J,Yonemitsu J,Yoshida N,Fumimori T,Oizumi K

    更新日期:2001-01-01 00:00:00

  • Viral breakthrough during lamivudine therapy for chronic hepatitis B.

    abstract::The mainstay of therapy for patients with chronic hepatitis B is inhibition of the replicative cycle of hepatitis B virus (HBV) in hepatocytes. Antiviral agents have different potencies. The measurement of HBV DNA in serum can monitor the potency of these therapeutic agents. Viral breakthrough may occur during therapy...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000074990

    authors: Leung N

    更新日期:2003-01-01 00:00:00

  • Epidemiology of mammalian hepatitis E virus infection.

    abstract::Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000342301

    authors: Kaba M,Moal V,Gérolami R,Colson P

    更新日期:2013-01-01 00:00:00

  • Imaging of early hepatocellular carcinoma and adenomatous hyperplasia (dysplastic nodules) with dynamic ct and a combination of CT and angiography: experience with resected liver specimens.

    abstract::Early hepatocellular carcinoma (HCC) as defined by the Liver Cancer Study Group of Japan would correspond to high-grade dysplastic nodules with small foci of HCC in the majority of cases, using the classification system proposed by the International Working Party. A large number of early HCCs were revealed to be hypo-...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000078473

    authors: Takayasu K,Muramatsu Y,Mizuguchi Y,Moriyama N,Ojima H

    更新日期:2004-01-01 00:00:00