Leukocyte migration inhibition detects cross-reacting antigens between cells transformed by Epstein-Barr virus (EBV) and EBV-like simian viruses.

abstract：BACKGROUND:Arboviruses co-circulating within a population that are transmitted by the same vector have the potential to cause coinfections. Coinfections with dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus (CHIKV) have been occurring in Brazil, but it is not well-understood how human responses vary during...

journal_title：Intervirology

authors： Sánchez-Arcila JC,Badolato-Correa J,de Souza TMA,Paiva IA,Barbosa LS,Nunes PCG,Lima MDRQ,Dos Santos FB,Damasco PV,da Cunha RV,Azeredo EL,de Oliveira-Pinto LM

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Giant viruses of the Megavirales order have been neglected in the literature because they are removed from samples during viral purification for viral metagenomic studies. Isolation via amoeba coculture has low efficiency and is extremely time-consuming. Thus, our objective was to improve Megavirales detectio...

journal_title：Intervirology

authors： Slimani M,Pagnier I,Boughalmi M,Raoult D,La Scola B

更新日期：2013-01-01 00:00:00

abstract：:In order to assess the risk of transmission of viral diseases during floods, the viral burden in flooded areas of the city of Dresden (Germany) in August 2002 was investigated. Water samples were collected from 9 sampling sites and tested for the presence of 11 enteric viral pathogens. As a control, water samples from...

journal_title：Intervirology

authors： Rohayem J,Dumke R,Jaeger K,Schröter-Bobsin U,Mogel M,Kruse A,Jacobs E,Rethwilm A

更新日期：2006-01-01 00:00:00

abstract：:Damage and necrosis of hepatocytes in viral hepatitis C is considered to be immune mediated as in hepatitis B. Hepatocellular necrosis accompanies infiltration of lymphocytes and this feature, called necroinflammation, characterizes all types of viral hepatitis and corresponds to the histological expression of hepatit...

journal_title：Intervirology

authors： Uchida T

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To clarify the value of contrast-enhanced harmonic ultrasonography (US) with Sonazoid, a second-generation US contrast agent, in the differential diagnosis of liver tumors compared to dynamic CT. METHODS:A total of 249 hepatic nodules in 214 patients were studied; these included 177 hepatocellular carcinomas...

journal_title：Intervirology

authors： Hatanaka K,Kudo M,Minami Y,Ueda T,Tatsumi C,Kitai S,Takahashi S,Inoue T,Hagiwara S,Chung H,Ueshima K,Maekawa K

更新日期：2008-01-01 00:00:00

abstract：:The members of the viral family Hepadnaviridae comprise one of the smallest enveloped DNA viruses and cause acute and chronic infections in mammals and birds, leading to large virus and antigen loads in the blood. They have a restricted host range and depend on differentiated hepatocytes for replication. Hepatitis B v...

journal_title：Intervirology

authors： Glebe D,König A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin molecule of influenza virus is considered as an ideal model to study biological processes as well as the effect of glycosylation on the function of glycoproteins. OBJECTIVES:The large subunit of the influenza virus A/New Caledonia/20/99 (H1N1) hemagglutinin (HA1) was expressed in recombina...

journal_title：Intervirology

authors： Farahmand B,Khodabandeh M,Mahboudi F,Fotouhi F,Saleh M,Barkhordari F,Tabatabaian M,Nasab FP,Kheiri MT

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:This study sought to investigate the presence of dengue virus binding proteins expressed on the surface of HepG2 cells and to determine if there were serotype specific differences in binding. METHODS:HepG2 cell membrane proteins were extracted and separated by SDS-PAGE, transferred to nitrocellulose membrane...

journal_title：Intervirology

authors： Jindadamrongwech S,Smith DR

更新日期：2004-01-01 00:00:00

abstract：:This review briefly summarises the recent knowledge about hantavirus infections and raises particular problems in hantavirus research that need further investigation. The following questions are addressed: (i) are hantaviruses distributed worldwide and what leads to new outbreaks, (ii) what is known about hantavirus e...

journal_title：Intervirology

authors： Ulrich R,Hjelle B,Pitra C,Krüger DH

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To understand the autoimmunity associated with chronic hepatitis C (CHC), we investigated autoantibodies (autoAbs) to CD69. METHODS:With this aim, we tested the reactivity of serum samples from patients with CHC and asymptomatic carriers of hepatitis C virus (HCV), as well as from patients with chronic hepat...

journal_title：Intervirology

authors： Okamoto N,Yotsuyanagi H,Ooka S,Matsui T,Suzuki Kurokawa M,Suzuki M,Iino S,Nishioka K,Kato T

更新日期：2003-01-01 00:00:00

abstract：:Among patients undergoing maintenance hemodialysis, a high prevalence of hepatitis C virus (HCV) infection can be observed. In a prospective study, sera of 273 patients were examined for the presence of HCV infection by serological tests and by PCR. Thirty-five patients (12.8%) were HCV antibody positive, and in 31 of...

journal_title：Intervirology

authors： Schröter M,Feucht HH,Schäfer P,Zöllner B,Laufs R

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Cervical cancer is the third most common malignancy in females. Since the human papillomavirus (HPV) genotype can vary geographically, it is essential to define its genotypic distribution before establishing health care policies and vaccination programs in any given area. The aim of this study was to determin...

journal_title：Intervirology

authors： Taghizadeh E,Taheri F,Abdolkarimi H,Ghorbani Renani P,Gheibi Hayat SM

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Human Salivirus (SalV) has been associated with gastroenteritis on all continents. METHODS:This paper presents the real-time RT-PCR assay for the detection of SalV in clinical fecal samples collected from 192 hospitalized children with acute gastroenteritis in Piedmont, Italy. RESULTS:The most commonly dete...

journal_title：Intervirology

authors： Bergallo M,Daprà V,Rassu M,Bonamin S,Cuccu R,Calvi C,Montanari P,Galliano I

更新日期：2018-01-01 00:00:00

abstract：:Analysis of translation products synthesized in vitro in the presence of a mixture of brome mosaic virus (BMV) RNAs 1, 2, 3, and 4 usually shows a predominance of coat protein, coded by RNA4. The proportion of products directed by RNAs 1 and 2 decreased at saturating concentrations of BMV RNA and in the presence of 7-...

journal_title：Intervirology

authors： Pyne JW,Hall TC

更新日期：1979-01-01 00:00:00

abstract：:The kinetics of Aleutian disease virus (ADV) replication in mink lymphocytes was followed by the analysis of virus-specific antigens, infectious virus, and viral DNA. Stimulation with pokeweed mitogen (PWM; 20 micrograms/ml) increased the synthesis of ADV DNA in cultivated cells of the B-cell fraction. Maximum virus t...

journal_title：Intervirology

authors： Kaaden OR,Haas L,Löchelt M,Roth S

更新日期：1986-01-01 00:00:00

abstract：:Scrapie brain homogenate was mixed with mouse peritoneal macrophages in vitro. After 2 h of incubation at 37 degrees, a portion of the scrapie infectivity was associated with macrophages. In contrast, very little infectivity was associated with kidney cells that had been exposed to scrapie brain homogenate. After incu...

journal_title：Intervirology

authors： Carp RI,Callahan SM

更新日期：1981-01-01 00:00:00

abstract：:Cytomegalovirus infection of Brown Norway rats was studied after intraperitoneal or subcutaneous inoculation of virus. No clinical illness was apparent during the 1st month postinfection (p.i.). Low titers of virus were detected in many organs at day 4 p.i. for the intraperitoneally inoculated animals and at day 11 p....

journal_title：Intervirology

authors： Bruggeman CA,Meijer H,Bosman F,van Boven CP

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To study the anti-herpes simplex virus (HSV) activity of a (1→6)-(1→3)-β-D-glucan isolated from Agaricus brasiliensis fruiting bodies (FR) as well as its chemically sulfated derivative (FR-S). METHODS:The antiherpetic activity and mechanism of action was studied by viral plaque assay applying different metho...

journal_title：Intervirology

authors： Cardozo FT,Camelini CM,Leal PC,Kratz JM,Nunes RJ,Mendonça MM,Simões CM

更新日期：2014-01-01 00:00:00

abstract：:The 20-nm noninfectious empty envelope particles carrying the hepatitis B surface antigen are secreted in large excess from hepatocytes during a hepatitis B infection. Similar particles produced in cell lines or yeast are an efficient vaccine against hepatitis B virus. We have analyzed the assembly of 20-nm particles ...

journal_title：Intervirology

authors： Prange R,Mangold CM,Hilfrich R,Streeck RE

更新日期：1995-01-01 00:00:00

abstract：:The mainstay of therapy for patients with chronic hepatitis B is inhibition of the replicative cycle of hepatitis B virus (HBV) in hepatocytes. Antiviral agents have different potencies. The measurement of HBV DNA in serum can monitor the potency of these therapeutic agents. Viral breakthrough may occur during therapy...

journal_title：Intervirology

authors： Leung N

更新日期：2003-01-01 00:00:00

abstract：:The effects of cyclosporin A (CsA) upon the pathogenesis of primary cytomegalovirus (CMV) infection were investigated. Hartley and strain 2 guinea pigs were inoculated subcutaneously on day 0 with 10(4) TCD50 of virulent, salivary-gland-passaged guinea pig CMV and received oral CsA (20 mg/kg/day) for 14 days. CMV-infe...

journal_title：Intervirology

authors： Bia FJ,Lucia HL,Bia MJ,Vine W,Tuttle A

更新日期：1985-01-01 00:00:00

abstract：:Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

journal_title：Intervirology

authors： Kaba M,Moal V,Gérolami R,Colson P

更新日期：2013-01-01 00:00:00

abstract：:Nasal natural killer (NK)/T cell lymphoma is a peculiar lymphoma with a unique immunophenotype. Etiologically, in 1990, the authors first demonstrated the presence of Epstein-Barr virus (EBV) genomes and their products in this lymphoma. EBV-specific cytotoxic T lymphocytes (CTL) are very important in controlling the l...

journal_title：Intervirology

authors： Nagamine M,Kishibe K,Takahara M,Nagato T,Ishii H,Bandoh N,Ogino T,Harabuchi Y

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:To date there are no reports of molecular and phylogenetic analyses of human influenza virus in Tehran, Iran. OBJECTIVES:We isolated and characterized circulating influenza viruses in a sample of patients in Tehran. METHODS:Nasal and pharyngeal swabs were collected from 57 individuals who were suspected of...

journal_title：Intervirology

authors： Soltani Z,Hosseini M,Shahidi M,Hedayati M,Kheiri MT

更新日期：2009-01-01 00:00:00

abstract：:Bovine adenoviruses (BAVs) are important pathogens causing significant economic losses to the cattle industry. We have been interested in the differences among serotypes of these viruses, particularly in their pathogenicity and host range. As part of our efforts to better understand these viruses, we have determined t...

journal_title：Intervirology

authors： Yagubi A,Ojkic D,Bautista DS,Haj-Ahmad Y

更新日期：1998-01-01 00:00:00

abstract：:HIV-2 is responsible for a limited epidemic in West Africa. Around 20% of all infected patients will progress to AIDS, and will need antiretroviral therapy. Unfortunately, antiretrovirals were developed to suppress HIV-1 replication; not all of them are active against HIV-2, e.g. all nonnucleoside reverse transcriptas...

journal_title：Intervirology

authors： Camacho RJ

更新日期：2012-01-01 00:00:00

abstract：AIMS:The objective of this work was to study the distribution of hepatitis C virus (HCV) genotypes and subtypes from 2010 to 2015 in 1,221 anti-HCV/HCV-RNA-positive specimens from patients living in the metropolitan area of Naples, since HCV genotypes and subtypes remain cornerstones in the management of chronic HCV in...

journal_title：Intervirology

authors： Grimaldi E,Della Pepa ME,Martora F,Magliocca P,Iovene MR,Coppola N,Donnarumma G,Galdiero M

更新日期：2017-01-01 00:00:00

abstract：:In this article, a statistical score method for comparison of partial genomic regions in their representatives of full-length genome of hepatitis E virus (HEV) for genotyping was developed. The critical values of the statistics for hypothesis testing were generated through Monte Carlo simulations. It was found that fr...

journal_title：Intervirology

authors： Xun P,Chen F,Dong C,Qian G,Lai D,Meng J

更新日期：2007-01-01 00:00:00

abstract：:The intracellular fate of 3H-labeled exogenous herpes simplex virus type 2 DNA following the exposure of recipient cells to selected DNA facilitators and the ultrastructural changes which ensued in transfected cultures were examined. In most cases, electron microscopic radioautography demonstrated that exogenous DNA r...

journal_title：Intervirology

authors： Marciano-Cabral F,Cabral GA,Taylor MM,Patterson M,Farber FE

更新日期：1981-01-01 00:00:00

abstract：AIMS:The aim of the present study is the preliminary characterization of an El Tor vibriophage M4 (ATCC 51352-B4). METHODS:We studied the growth characteristics and sustainability of this phage under various stresses like temperature, pH, and UV. The phage morphology and phage genome were also examined using electron ...

journal_title：Intervirology

authors： Das S,Ghosh AN

更新日期：2017-01-01 00:00:00