Inhibition of chemical Epstein-Barr virus induction by dimethyl sulfoxide and related polar compounds.

Abstract:

:Dimethyl sulfoxide and twelve related polar compounds, capable of inducing differentiation of murine erythroleukemia cells, markedly inhibited induction of Epstein-Barr virus antigens in virus producer and nonproducer lymphoblastoid cells exposed to 12-O-tetradecanoylphorbol-13-acetate, n-butyric acid, 5-iodo-2'-deoxyuridine, and a combination of 12-O-tetradecanoylphorbol-13-acetate and n-butyric acid. The concentration at which these compounds caused 90% inhibition of antigen induction corresponded to that optimal for induction of differentiation. At the same concentrations, polar compounds did not affect cell viability or virus induction by superinfection with Epstein-Barr virus recovered from P3HR-1 cells. The inhibitory activity was reversible. Three nonpolar differentiating compounds revealed no inhibitory activity.

journal_name

Intervirology

journal_title

Intervirology

authors

Yanase S,Sugawara K

doi

10.1159/000150088

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

163-8

issue

3

eissn

0300-5526

issn

1423-0100

journal_volume

30

pub_type

杂志文章
  • Temperature-dependent phosphorylation state of the H5R protein synthesised at the early stage of infection in cells infected with vaccinia virus ts mutants of the B1R and F10L protein kinases.

    abstract::The phosphorylation state of H5R protein was investigated by two-dimensional gel electrophoresis of proteins of BSC-40 cells infected at 32 degrees or 39.5 degrees with vaccinia virus ts mutants of the viral B1R or F10L protein kinase genes. A temperature-dependent increase of underphosphorylated H5R protein (pI 6.8) ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000025025

    authors: Beaud G,Beaud R

    更新日期:2000-01-01 00:00:00

  • Barley yellow mosaic virus (BaYMV) and BaYMV-M: two different viruses.

    abstract::Serological and physical properties of isolated particles as well as reactions of barley cultivars after virus inoculation showed that the yellow disease of barley is caused by different viruses. Results summarized in this paper suggest that the European isolates BaYMV-So and BaYMV-NM are closely related to, or identi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150132

    authors: Huth W,Adams MJ

    更新日期:1990-01-01 00:00:00

  • Prevalence of hepatitis E virus antibodies in patients with chronic hepatitis B and chronic hepatitis C.

    abstract:OBJECTIVES:To investigate the prevalence of hepatitis E virus (HEV) among patients with chronic hepatitis B and chronic hepatitis C, serum samples were collected between January and December 2004 from patients with chronic hepatitis B and chronic hepatitis C. METHODS:There were 190 adult patients with chronic hepatiti...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000103916

    authors: Bayram A,Eksi F,Mehli M,Sözen E

    更新日期:2007-01-01 00:00:00

  • Dengue in travellers is still underestimated.

    abstract:BACKGROUND:Dengue fever (DF), one of the main emerging virus diseases, also increases in German travellers, due to the increasing number of travellers to tropical regions. METHODS:We determined antibodies against DF virus in a group (n = 149) of long-distance travellers in order to evaluate the risk of acquiring DF. S...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000131667

    authors: Allwinn R,Hofknecht N,Doerr HW

    更新日期:2008-01-01 00:00:00

  • Differential diagnosis of hepatic tumors: value of contrast-enhanced harmonic sonography using the newly developed contrast agent, Sonazoid.

    abstract:OBJECTIVE:To clarify the value of contrast-enhanced harmonic ultrasonography (US) with Sonazoid, a second-generation US contrast agent, in the differential diagnosis of liver tumors compared to dynamic CT. METHODS:A total of 249 hepatic nodules in 214 patients were studied; these included 177 hepatocellular carcinomas...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000122600

    authors: Hatanaka K,Kudo M,Minami Y,Ueda T,Tatsumi C,Kitai S,Takahashi S,Inoue T,Hagiwara S,Chung H,Ueshima K,Maekawa K

    更新日期:2008-01-01 00:00:00

  • Progressive changes in hepatoma cells stably transfected with hepatitis B virus X gene.

    abstract:OBJECTIVE:The aim of this study is to investigate the molecular mechanism of hepatocellular carcinoma (HCC) development induced by hepatitis B virus X protein (HBx). METHODS:We previously established a H7402-X cell line that constitutively expresses HBx protein. In the present study, H7402-X gene expression profiles a...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000120289

    authors: Ye L,Dong N,Wang Q,Xu Z,Cai N,Wang H,Zhang X

    更新日期:2008-01-01 00:00:00

  • Pathology of hepatitis C.

    abstract::Damage and necrosis of hepatocytes in viral hepatitis C is considered to be immune mediated as in hepatitis B. Hepatocellular necrosis accompanies infiltration of lymphocytes and this feature, called necroinflammation, characterizes all types of viral hepatitis and corresponds to the histological expression of hepatit...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150367

    authors: Uchida T

    更新日期:1994-01-01 00:00:00

  • Induction of apoptosis in rabbit kidney cell under high-level expression of bovine herpesvirus 1 U(s) ORF8 product.

    abstract:OBJECTIVE:The open reading frame 8 (ORF8) within the short unique (U(s)) region of the bovine herpesvirus 1 (BHV-1) genome was predicted to encode a protein with homology to U(s)9 protein of other alpha herpesviruses. The aim of this study is to identify the protein encoded by the U(s) ORF8 and to examine the effect of...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000063236

    authors: Nakamichi K,Matsumoto Y,Tohya Y,Otsuka H

    更新日期:2002-01-01 00:00:00

  • Leukocyte migration inhibition detects cross-reacting antigens between cells transformed by Epstein-Barr virus (EBV) and EBV-like simian viruses.

    abstract::The leukocyte migration inhibition (LMI) technique was used to measure the T cell-mediated immune response of Epstein-Barr-virus (EBV)-seropositive human donors to antigens associated with B cell lines of simian origin, transformed by simian EBV-like viruses, Herpesvirus papio (HVP), H. pan, H. gorilla and H. pongo. E...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149691

    authors: Szigeti R,Rabin H,Timar L,Klein G

    更新日期:1986-01-01 00:00:00

  • Time-course of cowpea chlorotic mottle virus RNA replication.

    abstract::In a synchronous infection of cowpea chlorotic mottle virus in cowpea leaves, the three largest viral RNA components were synthesized throughout the infection at relatively constant ratios of two molecules of component 3 to one each of components 1 and 2. Component 4 (the coat protein message) was produced minimally d...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000148929

    authors: Dawson WO

    更新日期:1978-01-01 00:00:00

  • Experimental and spontaneous mucosal disease of cattle: a validation of Koch's postulates in the definition of pathogenesis.

    abstract::The complex etiology of mucosal disease of cattle has been unravelled by experimental reproduction of the fatal syndrome, thereby validating Koch's postulates. The causal virus, bovine virus diarrhea virus (BVDV), has two biotypes, noncytopathogenic and cytopathogenic; the former can infect the early bovine fetus, ind...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150295

    authors: Brownlie J,Clarke MC

    更新日期:1993-01-01 00:00:00

  • Cellular DNA synthesis associated with activation of latent herpes simplex virus in cell culture.

    abstract::Herpes simplex virus type 1 (HSV-1) latency was established in human embryo lung (HEL) cells by treatment with (E)-5-(2'-bromovinyl)-2'-deoxyuridine and human leukocyte interferon and subsequent temperature increase (from 37 degrees to 40.5 degrees). This in vitro system was used to study reactivation after temperatur...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149668

    authors: Vonka V,Shiraki K,Wrzos J,Rapp F

    更新日期:1986-01-01 00:00:00

  • Interaction of Autographa californica nuclear polyhedrosis virus with two nonpermissive cell lines.

    abstract::The interaction of Autographa californica nuclear polyhedrosis virus with two nonpermissive cell lines was investigated. The insect cell line, CP 169, and the Chinese hamster cell line, CHO-K1, were able to adsorb and engulf virus particles, but there was no evidence for viral replication in these cells based on virus...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149522

    authors: Gröner A,Granados RR,Burand JP

    更新日期:1984-01-01 00:00:00

  • Human cytomegalovirus escape from immune detection.

    abstract::Human cytomegalovirus (CMV) has devised numerous means of escaping immune surveillance. The CMV genome encodes at least 4 genes involved in downregulating surface expression of HLA class I molecules. In addition, it sequesters CC chemokines, induces Fc receptors, interferes with induction of HLA class II antigens, and...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000053964

    authors: Michelson S

    更新日期:1999-01-01 00:00:00

  • Chikungunya virus induces a more moderate cytopathic effect in mosquito cells than in mammalian cells.

    abstract:OBJECTIVES:Chikungunya virus (CHIKV) is an alphavirus belonging to the Togaviridae family. Alphaviruses cause a chronic non-cytopathic infection in mosquito cells, while they develop a highly cytopathic infection in cells originating from various vertebrates. In this study, we compared the cytopathic effect (CPE) induc...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000339985

    authors: Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-nuegoonpipat A,Tao R,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

    更新日期:2013-01-01 00:00:00

  • Historical Discoveries on Viruses in the Environment and Their Impact on Public Health.

    abstract:BACKGROUND:Transmission of many viruses occurs by direct transmission during a close contact between two hosts, or by an indirect transmission through the environment. Several and often interconnected factors, both abiotic and biotic, determine the persistence of these viruses released in the environment, which can las...

    journal_title:Intervirology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1159/000511575

    authors: Labadie T,Batéjat C,Leclercq I,Manuguerra JC

    更新日期:2020-01-01 00:00:00

  • Biological properties of Junin virus proteins. I. Identification of the immunogenic glycoprotein.

    abstract::Purified Junin virus was disrupted by nonionic detergent treatment (Triton X-100), and subviral components were separated by ultracentrifugation. Only the soluble fraction, containing all of the major glycoprotein (mol.wt. 38,000), induced the formation of neutralizing antibodies in laboratory animals and protected th...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149136

    authors: Cresta B,Padula P,de Martinez Segovia M

    更新日期:1980-01-01 00:00:00

  • Inhibition of cardiolipin synthesis following infection with herpes simplex virus.

    abstract::The results of this study show that the synthesis of the inner mitochondrial membrane phospholipid, cardiolipin, is markedly inhibited following infection of human embryonic lung or hamster embryo fibroblast cells with herpes simplex virus type 1 or 2. The synthesis of other phospholipids, i.e., phosphatidylcholine, p...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149969

    authors: Tucker T,Steiner MR,Steiner S

    更新日期:1974-01-01 00:00:00

  • Effects of poliovirus replication on undifferentiated and differentiated monocytic U937 cells: comparative studies with human macrophages.

    abstract::Poliovirus infection of either undifferentiated or differentiated U937 cells produced a decrease in the percentage of cells positive for the surface expression of the CD4, CD11c, CD14, or 8E11 antigens. The number of 4F2 surface molecules per cell increased in infected normal U937 cells, but was unaffected in differen...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150194

    authors: López-Guerrero JA,Cabañas C,Bernabeu C,Fresno M,Alonso MA

    更新日期:1991-01-01 00:00:00

  • Genomic heterogeneities in bovine herpesvirus type 1 viral isolates: a major variant selected from a field isolate.

    abstract::We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150192

    authors: Simard C,LaBoissière S,Séguin C,Trudel M

    更新日期:1991-01-01 00:00:00

  • Prediction of efficacy of interferon treatment of chronic hepatitis C and occurrence of HCC after interferon treatment by a new classification.

    abstract::One hundred and twenty-one chronic hepatitis C patients were administered interferon (IFN) and divided into two groups: 31 complete responders (CR) with prolonged HCV-RNA negative 1 year after treatment and 90 non-complete responders (non-CR), including partial responders (PR) with transiently negative HCV-RNA and non...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000082095

    authors: Kim KI,Sasase N,Taniguchi M,Mita K,Kim SR,Tanaka K,Hayashi Y

    更新日期:2005-01-01 00:00:00

  • Serologic comparison of hepatitis A antigen to echovirus 25 isolate CR69(076) recovered from a patient with viral hepatitis.

    abstract::A serologic comparison was performed by immune electron microscopy between hepatitis A antigen (related to the MS-1 strain of hepatitis A virus) and a viral isolate, CR69(076), from the stool of a patient in Costa Rica with viral hepatitis. CR69(076) was not antigenically related to hepatitis A antigen but was related...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149486

    authors: Dienstag JL,Pelon W,Tyeryar F,Purcell RH

    更新日期:1975-01-01 00:00:00

  • Distribution of Hepatitis C Virus Genotypes and Subtypes in the Metropolitan Area of Naples, Italy, in the Era of Interferon-Free Regimens.

    abstract:AIMS:The objective of this work was to study the distribution of hepatitis C virus (HCV) genotypes and subtypes from 2010 to 2015 in 1,221 anti-HCV/HCV-RNA-positive specimens from patients living in the metropolitan area of Naples, since HCV genotypes and subtypes remain cornerstones in the management of chronic HCV in...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000481821

    authors: Grimaldi E,Della Pepa ME,Martora F,Magliocca P,Iovene MR,Coppola N,Donnarumma G,Galdiero M

    更新日期:2017-01-01 00:00:00

  • Characterization of two temperate Lactobacillus paracasei bacteriophages: morphology, kinetics and adsorption.

    abstract:BACKGROUND/AIMS:Adsorption and kinetic parameters, latent period, burst size and burst time, are characteristics of phage/host systems and can be affected by several environmental factors. As only few studies have focused on temperate dairy phages, we characterized these parameters on temperate Lactobacillus paracasei ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000369207

    authors: Mercanti DJ,Ackermann HW,Quiberoni A

    更新日期:2015-01-01 00:00:00

  • HLA-B alleles B*15:01 and B*15:02: opposite association with hepatitis C virus infection in Chinese voluntary blood donors.

    abstract:BACKGROUND:Although human leukocyte antigens (HLA) have been shown in association with the outcomes of hepatitis C virus (HCV) infection among different ethnic groups, such studies remain absent in China, where the HCV prevalence is higher than the global average. METHODS:In this study, 426 HCV-infected and 709 uninfe...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000369209

    authors: Xiong H,Huang J,Rong X,Zhang M,Huang K,Xu R,Wang M,Li C,Liao Q,Xia W,Luo G,Ye X,Lu L,Fu Y,Guo T,Nelson K

    更新日期:2015-01-01 00:00:00

  • Use of Multiplex Polymerase Chain Reaction for Detection of High-Risk Human Papillomavirus Genotypes in Women Attending Routine Cervical Cancer Screening in Harare.

    abstract:BACKGROUND/AIMS:In Zimbabwe, cervical cancer is screened through cytology and visual inspection with acetic acid and cervicography (VIAC). The effectiveness of these methods can be increased if complemented by a human papillomavirus DNA detection tool since most cervical cancer cases are caused by persistent infection ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000502206

    authors: Marembo T,Dube Mandishora R,Borok M

    更新日期:2019-01-01 00:00:00

  • Epidemiology of mammalian hepatitis E virus infection.

    abstract::Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000342301

    authors: Kaba M,Moal V,Gérolami R,Colson P

    更新日期:2013-01-01 00:00:00

  • Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection.

    abstract::Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by int...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000373891

    authors: Li TC,Yoshizaki S,Ami Y,Suzaki Y,Yang T,Takeda N,Takaji W

    更新日期:2015-01-01 00:00:00

  • Intracellular pools of thymidine reduce the antiviral action of acyclovir.

    abstract::Acyclovir inhibits herpes simplex virus (HSV) infections better in human fibroblasts than in green monkey kidney cells. Thymidine and acyclovir compete for the active site of HSV thymidine kinase. Large intracellular pools of thymidine found by high-performance liquid chromatography (HPLC) seemed to be responsible for...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149373

    authors: Harmenberg J

    更新日期:1983-01-01 00:00:00

  • Hepatitis C virus genotype in blood donors and associated liver disease in Indonesia.

    abstract:OBJECTIVE:The aim of this study was to investigate the distribution of hepatitis C virus (HCV) genotype and the possible association between genotype and HCV-associated liver disease in Indonesia. METHODS:32 anti-HCV-positive asymptomatic carriers (AC), 55 chronic hepatitis (CH), 41 liver cirrhosis (LC), and 35 hepato...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000205515

    authors: Utama A,Budiarto BR,Monasari D,Octavia TI,Chandra IS,Gani RA,Hasan I,Sanityoso A,Miskad UA,Yusuf I,Lesmana LA,Sulaiman A,Tai S

    更新日期:2008-01-01 00:00:00