Abstract:
:In a synchronous infection of cowpea chlorotic mottle virus in cowpea leaves, the three largest viral RNA components were synthesized throughout the infection at relatively constant ratios of two molecules of component 3 to one each of components 1 and 2. Component 4 (the coat protein message) was produced minimally during the initial stages of the infection, and as the infection progressed the proportion of component 4 continuously increased. The replicative forms of components 1, 2, and 3 were produced with kinetics similar to those of the corresponding single-stranded molecules.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Dawson WOdoi
10.1159/000148929subject
Has Abstractpub_date
1978-01-01 00:00:00pages
119-28issue
2eissn
0300-5526issn
1423-0100journal_volume
9pub_type
杂志文章相关文献
INTERVIROLOGY文献大全abstract::Two closely related viruses were isolated from the blood of bovines near Darwin, Northern Territory, Australia. When studies of virus morphology indicated that these were rhabdoviruses, serologic studies were done. These isolates are closely related or identical and are related to, but distinct from, the rabies-relate...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150274
更新日期:1992-01-01 00:00:00
abstract::Viroids are minute unencapsidated non-coding circular RNAs known to be present and to cause diseases only in plants. Infections were associated with the occurrence of specific single-stranded RNAs similar in size to miRNAs and endogenous small interfering RNAs, and viroid pathogenicity is suspected to occur through RN...
journal_title:Intervirology
pub_type: 新闻
doi:10.1159/000509212
更新日期:2019-01-01 00:00:00
abstract::The morphology, assembly, and accumulation sites of rhabdovirus particles in Peregrinus maidis planthoppers infected with a Hawaiian isolate of maize mosaic virus (MMV) were studied. These particles were usually bullet-shaped, but were sometimes bacilliform, and averaged 234 and 247 nm, respectively, in length and 60 ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149616
更新日期:1985-01-01 00:00:00
abstract::The distribution of related sequences between the genomes of pseudorabies virus (PRV) and herpes simplex virus, types 1 (HSV-1) and 2 (HSV-2), was determined. Approximately 7% of the sequences in PRV are shared by HSV-1 and HSV-2 DNAs. By means of the Southern blot technique, it was found that the homologous sequences...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149106
更新日期:1980-01-01 00:00:00
abstract::The critical point dried (CPD) whole cell technique was applied to the study of the morphogenesis and morphology of rabies virus and vesicular stomatitis virus (VSV) in mouse neuroblastoma and baby hamster kidney (BHK) cells. With the stereoscopic technique, progeny viruses at the cell surface and within the cytoplasm...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000148939
更新日期:1978-01-01 00:00:00
abstract::The leukocyte migration inhibition (LMI) technique was used to measure the T cell-mediated immune response of Epstein-Barr-virus (EBV)-seropositive human donors to antigens associated with B cell lines of simian origin, transformed by simian EBV-like viruses, Herpesvirus papio (HVP), H. pan, H. gorilla and H. pongo. E...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149691
更新日期:1986-01-01 00:00:00
abstract::Virus-associated DNA polymerase activity has recently been proposed for the detection of human cytomegalovirus (HCMV) in urine, a method that should allow rapid and quantitative determination of the viral load. In this report, the virus-associated DNA polymerase activity recovered from the urine of a group of patients...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150530
更新日期:1996-01-01 00:00:00
abstract::Hepatitis B virus (HBV) is one of the major causative agents of hepatocellular carcinoma (HCC) in Southeast Asia where HBV genotype B (HBV/B) and genotype C (HBV/C) are prevalent. Clinical and virological differences were evaluated between HCC patients in Japan and Taiwan, all of whom were infected with HBV/B and HBV/...
journal_title:Intervirology
pub_type: 杂志文章,评审
doi:10.1159/000075000
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To explore the host transcription factor E2F-1 and/or any mechanisms that may support viral entry and its effect on the HSV-1 production in anti-CD3-activated Jurkat cells. METHODS:The expressions of ICP4, HVEM and E2F-1 were studied using reverse transcription-PCR and Western blot. HSV-1 production was det...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000437264
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000100565
更新日期:2007-01-01 00:00:00
abstract::The transcriptases of several influenza viruses were tested for pH and temperature dependence and for thermal stability. Marked differences in pH dependence and thermostability were determined. ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149012
更新日期:1979-01-01 00:00:00
abstract::In chicken cells infected by Sindbis virus and exposed to a variety of membrane-active compounds, virus release was inhibited. In infected cells exposed to antiserum directed against the virion glycoproteins E1 or E2, retinol, cortisone, Pb++ or insulin, the processing of two Sindbis virus precursor polypeptides which...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149063
更新日期:1979-01-01 00:00:00
abstract::The kinetics of Aleutian disease virus (ADV) replication in mink lymphocytes was followed by the analysis of virus-specific antigens, infectious virus, and viral DNA. Stimulation with pokeweed mitogen (PWM; 20 micrograms/ml) increased the synthesis of ADV DNA in cultivated cells of the B-cell fraction. Maximum virus t...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149676
更新日期:1986-01-01 00:00:00
abstract::The Holland strain of anatid herpesvirus (AHV) was 2-to 10-fold more efficiently plaqued under liquid medium or semisolid medium containing methylcellulose than in media containing agar, agarose, or Nobel agar. Virus adsorption was complete in 45 min, with the maximum virus titers obtained under liquid medium at 48 h ...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149193
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVES:Data on drug-resistant mutations (DRMs) in HIV-1-infected therapy-naïve children are scarce. The aim of this study was to determine the HIV-1 subtype distribution and the prevalence of DRMs in therapy-naïve HIV-1-infected children who received routine care at the University Hospital Düsseldorf, Düsseldorf, G...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000477811
更新日期:2016-01-01 00:00:00
abstract::Previous reports from this laboratory demonstrated that persistent infections could be established in Jurkat cells with wild-type vaccinia virus (Jvac). The infected cells elicit increased expression of IL-2, IL-2Ralpha and IL-6 but not of IL-1beta nor of interferon-gamma. The persistently infected cells are also capa...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000081734
更新日期:2005-01-01 00:00:00
abstract::This review summarizes current strategies for the treatment of human cytomegalovirus (CMV) infection/diseases in high-risk patients such as transplant recipients and AIDS patients. Since the major drugs ganciclovir (Cytovene), foscarnet (Foscavir) and cidofovir (Vistide) are frequently associated with severe side effe...
journal_title:Intervirology
pub_type: 杂志文章,评审
doi:10.1159/000150568
更新日期:1997-01-01 00:00:00
abstract::Hepatitis B virus (HBV) core antigen (HBcAg) detected by the peroxidase-antiperoxidase technique was present in the nucleus and cytoplasm of some infected hepatocytes but only in the cytoplasm of other hepatocytes. When cells expressing HBcAg were examined by in situ hybridization for the presence of HBV DNA, the intr...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000149646
更新日期:1985-01-01 00:00:00
abstract::In this study, we analyzed the in vitro expression, potency and longevity of immune responses induced in a Balb/c mouse model by a synthetic HIV-1 GAG gene exhibiting a codon usage that was adapted to that of highly expressed mammalian genes (syngag). In contrast to a vector containing the wild-type (wt) GAG gene, the...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000067919
更新日期:2002-01-01 00:00:00
abstract::To evaluate the diagnostic value of nucleic-acid-sequence-based amplification (NASBA) for the detection of cytomegalovirus (CMV) infection in transplant recipients, we compared immediate early 1 (IE1) and late pp67 mRNA detection by NASBA with the antigenemia assay, PCR and viral culture in 72 renal transplant (RTx) r...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000053974
更新日期:1999-01-01 00:00:00
abstract::The use of bleach (hypochlorite) as a disinfectant for drug injection equipment in the intravenous-drug-using population was recommended early in the HIV-1/AIDS epidemic. Epidemiological studies have challenged the use of bleach as an effective measure to prevent HIV-1 transmission. However, in vitro HIV-1 coculture s...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000025015
更新日期:2000-01-01 00:00:00
abstract::The WU-virus (WUV), a novel polyomavirus, has recently been recovered from respiratory tract samples. Within a study collective of children with severe lower respiratory tract disease, 3% of the patients tested WUV positive. Viral loads ranged from 5 x 10(2) copies/ml to 1 x 10(4) copies/ml. The WUV genome-positive pa...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000209673
更新日期:2008-01-01 00:00:00
abstract::This review briefly summarises the recent knowledge about hantavirus infections and raises particular problems in hantavirus research that need further investigation. The following questions are addressed: (i) are hantaviruses distributed worldwide and what leads to new outbreaks, (ii) what is known about hantavirus e...
journal_title:Intervirology
pub_type: 杂志文章,评审
doi:10.1159/000067924
更新日期:2002-01-01 00:00:00
abstract::Examination of thin sections from the cerebral cortex of scrapie-infected hamster brains revealed characteristic circular 26-30 nm diameter tubulofilamentous particles, identical to those previously described in both experimentally induced scrapie in mice, hamsters and natural scrapie of sheep, bovine spongiform encep...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150269
更新日期:1992-01-01 00:00:00
abstract::An amyloid-like isoform of a 33- to 34-kD glycoprotein, termed as the scrapie prion protein (PrPsc), plays a critical role in transmissible spongiform encephalopathies of animals and humans. It has even been suggested to present the responsible infectious agent. This protein is a posttranslationally modified form of t...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150457
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Although human leukocyte antigens (HLA) have been shown in association with the outcomes of hepatitis C virus (HCV) infection among different ethnic groups, such studies remain absent in China, where the HCV prevalence is higher than the global average. METHODS:In this study, 426 HCV-infected and 709 uninfe...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000369209
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Hepatitis C virus (HCV) infection is a public health problem and a major cause of chronic hepatitis. This virus exhibits a great genetic variability, with 8 genotypes and numerous subtypes. The aim of this study was to evaluate the fluctuations of HCV subtypes during 2 decades in Venezuela. METHODS:HCV genot...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000505065
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To understand the autoimmunity associated with chronic hepatitis C (CHC), we investigated autoantibodies (autoAbs) to CD69. METHODS:With this aim, we tested the reactivity of serum samples from patients with CHC and asymptomatic carriers of hepatitis C virus (HCV), as well as from patients with chronic hepat...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000068126
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The aim was to identify the codon usage bias between the newly identified duck plague virus (DPV) UL35 gene (GenBank accession No. EF643558) and the UL35-like genes of 27 other reference herpesviruses. METHODS:A comparative analysis of the codon usage bias of the 28 herpesviruses was performed by using the C...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000231992
更新日期:2009-01-01 00:00:00
abstract::Dimethyl sulfoxide and twelve related polar compounds, capable of inducing differentiation of murine erythroleukemia cells, markedly inhibited induction of Epstein-Barr virus antigens in virus producer and nonproducer lymphoblastoid cells exposed to 12-O-tetradecanoylphorbol-13-acetate, n-butyric acid, 5-iodo-2'-deoxy...
journal_title:Intervirology
pub_type: 杂志文章
doi:10.1159/000150088
更新日期:1989-01-01 00:00:00