Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection.

Abstract:

:Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by intravenous injection. None of the animals demonstrated a positive sign for virus replication, indicating that rats and monkeys are not susceptible to ferret HEV.

journal_name

Intervirology

journal_title

Intervirology

authors

Li TC,Yoshizaki S,Ami Y,Suzaki Y,Yang T,Takeda N,Takaji W

doi

10.1159/000373891

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

139-42

issue

3

eissn

0300-5526

issn

1423-0100

pii

000373891

journal_volume

58

pub_type

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