Experimental and spontaneous mucosal disease of cattle: a validation of Koch's postulates in the definition of pathogenesis.

abstract：:SDS-polyacrylamide slab gel analysis of selected primate and nonprimate adenoviruses has shown these viruses to differ significantly at the polypeptide molecular level. It follows that data derived from study of a single adenovirus serotype are unique to that serotype and are not representative of the adenovirus group...

journal_title：Intervirology

authors： Marusyk RG,Cummings GT

更新日期：1978-01-01 00:00:00

abstract：:Despite decades of research, no aetiologic factor(s) for human breast cancer has been identified and the search for a causal agent has all but been abandoned during the past thirty years. Over 60 years ago, it was demonstrated that breast tumours in mice are caused by an oncornavirus, murine mammary tumour virus (MMTV...

journal_title：Intervirology

authors： Mant C,Hodgson S,Hobday R,D'Arrigo C,Cason J

更新日期：2004-01-01 00:00:00

abstract：:Despite the significant medical advances which have taken place in the last decades, acute diarrhoea cases remain a public health issue of major significance, with gastroenteritis agents being associated with severe symptoms in adults and high morbidity in infants and children. Regarding rotaviruses, while children ar...

journal_title：Intervirology

authors： Vontas A,Hadjicristodoulou C,Krikelis V,Petinaki E

更新日期：2019-01-01 00:00:00

abstract：:Transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are similar coronaviruses, causing diseases characterized by vomiting, diarrhea, and death from severe dehydration in piglets. Thus, they have caused huge losses to the swine-breeding industry worldwide. Nowadays, they are easily tra...

journal_title：Intervirology

authors： Yuan P,Yang Z,Song H,Wang K,Yang Y,Xie L,Huang S,Liu J,Ran L,Song Z

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Sandfly fever phleboviruses are endemic in Mediterranean countries. We report a febrile phlebovirus case in a Greek patient who presented signs of neuroinvasive infection. METHODS:In summer 2010, a 20-year-old male was admitted to hospital with fever and lethargy; he was a resident of central Macedonia, nort...

journal_title：Intervirology

authors： Papa A,Mallias J,Tsergouli K,Markou F,Poulou A,Milidis T

更新日期：2014-01-01 00:00:00

abstract：:A reverse transcriptase, polymerase chain reaction (RT-PCR) procedure was used to amplify a segment of the genome of turkey coronavirus (TCV) spanning portions of the matrix and nucleocapsid (MN) protein genes (approximately 1.1 kb). The MN gene region of three epidemiologically distinct TCV strains (Minnesota, NC95, ...

journal_title：Intervirology

authors： Breslin JJ,Smith LG,Fuller FJ,Guy JS

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Dengue fever (DF), one of the main emerging virus diseases, also increases in German travellers, due to the increasing number of travellers to tropical regions. METHODS:We determined antibodies against DF virus in a group (n = 149) of long-distance travellers in order to evaluate the risk of acquiring DF. S...

journal_title：Intervirology

authors： Allwinn R,Hofknecht N,Doerr HW

更新日期：2008-01-01 00:00:00

abstract：:Influenza PR8 particles resulting from strong treatment with caseinase C are spikeless, devoid of neuraminidase and hemagglutinin 1 and 2 glycopeptides, and contain a Schiff-negative polypeptide of about 13,000 molecular weight which exists as traces in intact virions. Their M-protein polypeptide content is reduced to...

journal_title：Intervirology

authors： Reginster M,Rentier B,Dierickx L

更新日期：1975-01-01 00:00:00

abstract：:5 patients with primary genital herpes simplex virus (HSV) infection were studied prospectively for the production of serum antibody reactivity as measured by the virus micro-neutralization test (NT), micro-solid phase radioimmunometric assay (micro-SPRIA), and antibody-dependent cellular-cytotoxic (ADCC) test. ADCC a...

journal_title：Intervirology

authors： Kohl S,Adam E,Matson DO,Kaufman RH,Dreesman GR

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:Some patients with chronic hepatitis C virus (HCV) infection fail to achieve complete early virologic response (EVR) despite a marked decrease in HCV RNA at 4 weeks. We investigated the characteristics and final treatment outcomes of this patient subpopulation. METHODS:A total of 516 patients with HCV genoty...

journal_title：Intervirology

authors： Toyoda H,Kumada T,Shimada N,Takaguchi K,Ide T,Sata M,Ginba H,Matsuyama K,Izumi N

更新日期：2014-01-01 00:00:00

abstract：:9-beta-D-Arabinofuranosyladenine (ara A) was shown to inhibit a specific step of tobacco mosaic virus (TMV) multiplication. The time course of the ara A-sensitive function occurred 'late' coinciding with the period of viral RNA and protein synthesis. When treatment began after viral RNA synthesis was established, 1.0 ...

journal_title：Intervirology

authors： Dawson WO,Lozoya-Saldana H

更新日期：1986-01-01 00:00:00

abstract：:Rotavirus is the most common cause of severe diarrhoea worldwide, affecting over 125 million young children every year in developing countries. The present study is a part of ongoing childhood diarrhoeal surveillance to determine the strain diversity of rotaviruses prevalent in Andaman and Nicobar Islands. From Octobe...

journal_title：Intervirology

authors： Reesu R,Bhattacharya D,Chaaithanya IK,Muruganandam N,Bharadwaj AP,Singhania M,Sugunan AP,Vijayachari P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To clarify the value of contrast-enhanced harmonic ultrasonography (US) with Sonazoid, a second-generation US contrast agent, in the differential diagnosis of liver tumors compared to dynamic CT. METHODS:A total of 249 hepatic nodules in 214 patients were studied; these included 177 hepatocellular carcinomas...

journal_title：Intervirology

authors： Hatanaka K,Kudo M,Minami Y,Ueda T,Tatsumi C,Kitai S,Takahashi S,Inoue T,Hagiwara S,Chung H,Ueshima K,Maekawa K

更新日期：2008-01-01 00:00:00

abstract：:The WU-virus (WUV), a novel polyomavirus, has recently been recovered from respiratory tract samples. Within a study collective of children with severe lower respiratory tract disease, 3% of the patients tested WUV positive. Viral loads ranged from 5 x 10(2) copies/ml to 1 x 10(4) copies/ml. The WUV genome-positive pa...

journal_title：Intervirology

authors： Kleines M,Scheithauer S,Hengst M,Honnef D,Ritter K,Mühler E,Häusler M,Rostamzadeh A

更新日期：2008-01-01 00:00:00

abstract：:Antibodies of individuals infected with the human immunodeficiency virus type 1 (HIV-1) were used to probe the antigenicity of the HIV-1 transmembrane protein of 41 kD (gp41) by antibody-reactive peptide scanning (Pepscan). Eleven distinct sequential antibody-binding sites were defined by testing reactivity to 339 ove...

journal_title：Intervirology

authors： Goudsmit J,Meloen RH,Brasseur R

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:Theiler's murine encephalomyelitis virus (TMEV) infection of mice is a widely used animal model for demyelinating disorders, such as multiple sclerosis (MS). The aim of the present study was to identify topographical differences of TMEV spread and demyelination in the brain of experimentally infected suscept...

journal_title：Intervirology

authors： Kummerfeld M,Seehusen F,Klein S,Ulrich R,Kreutzer R,Gerhauser I,Herder V,Baumgärtner W,Beineke A

更新日期：2012-01-01 00:00:00

abstract：:Cytomegalovirus infection of Brown Norway rats was studied after intraperitoneal or subcutaneous inoculation of virus. No clinical illness was apparent during the 1st month postinfection (p.i.). Low titers of virus were detected in many organs at day 4 p.i. for the intraperitoneally inoculated animals and at day 11 p....

journal_title：Intervirology

authors： Bruggeman CA,Meijer H,Bosman F,van Boven CP

更新日期：1985-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) is one of the major causative agents of hepatocellular carcinoma (HCC) in Southeast Asia where HBV genotype B (HBV/B) and genotype C (HBV/C) are prevalent. Clinical and virological differences were evaluated between HCC patients in Japan and Taiwan, all of whom were infected with HBV/B and HBV/...

journal_title：Intervirology

authors： Orito E,Mizokami M

更新日期：2003-01-01 00:00:00

abstract：:In Spodoptera frugiperda (SF IPLB-21) cells productively infected with S. frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV), we observed the synthesis of infected-cell-specific polypeptides (ICSPs) using the protein synthesis inhibitor cycloheximide (CX) and the DAN synthesis inhibitor cytosine arabinoside (A...

journal_title：Intervirology

authors： Liu HS,Bilimoria SL

更新日期：1997-01-01 00:00:00

abstract：:The actinomycin-D(AMD)-sensitive step of replication of three plant viruses - cowpea chlorotic mottle virus (CCMV), cowpea mosaic virus, and the cowpea strain of tobacco mosaic virus - in cowpea was specific for each virus. Different combinations of the viruses were examined in which leaves were inoculated with one vi...

journal_title：Intervirology

authors： Turner MS,Dawson WO

更新日期：1984-01-01 00:00:00

abstract：:Hybrid recombinant plasmids were constructed; they were composed of the herpes simplex virus type 2 (HSV2) thymidine kinase (tk) gene and DNA sequences of HSV2 that have been reported to induce morphological and/or oncogenic transformation of rodent cells in culture. Several plasmids were made in two versions, with or...

journal_title：Intervirology

authors： van den Berg FM,van Amstel PJ,Walboomers JM

更新日期：1985-01-01 00:00:00

abstract：:Immunopathologic mechanisms leading to liver tissue injury in hepatitis caused by hepatitis A virus (HAV) were studied in an autologous in vitro model. Data show virus-specific killing by liver-infiltrating T lymphocytes in man and support the hypothesis that hepatocellular damage as well as efficient elimination of v...

journal_title：Intervirology

authors： Vallbracht A,Fleischer B,Busch FW

更新日期：1993-01-01 00:00:00

abstract：:Damage and necrosis of hepatocytes in viral hepatitis C is considered to be immune mediated as in hepatitis B. Hepatocellular necrosis accompanies infiltration of lymphocytes and this feature, called necroinflammation, characterizes all types of viral hepatitis and corresponds to the histological expression of hepatit...

journal_title：Intervirology

authors： Uchida T

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:The open reading frame 8 (ORF8) within the short unique (U(s)) region of the bovine herpesvirus 1 (BHV-1) genome was predicted to encode a protein with homology to U(s)9 protein of other alpha herpesviruses. The aim of this study is to identify the protein encoded by the U(s) ORF8 and to examine the effect of...

journal_title：Intervirology

authors： Nakamichi K,Matsumoto Y,Tohya Y,Otsuka H

更新日期：2002-01-01 00:00:00

abstract：:An RNA virus was isolated from Trichoplusia ni larvae infected with inoculum of the baculovirus of Autographa californica. Physicochemical characterization has revealed a 35-nm virus with a density in CsCl of 1.3 g/cm3 and a sedimentation coefficient of 200S. The virus consisted of 10--15% single-stranded RNA with an ...

journal_title：Intervirology

authors： Morris TJ,Hess RT,Pinnock DE

更新日期：1979-01-01 00:00:00

abstract：:Plants mixedly infected with the U2 strain of tobacco mosaic virus (T2MV) and sunnhemp mosaic virus (SHMV) and grown at 35 degrees, yield particles of the same modal lengths (300 and 40 nm) as those found in plants singly infected with SHMV, but not in plants infected with T2MV, which yield only the long particles. At...

journal_title：Intervirology

authors： Skotnicki A,Gibbs A,Shaw DC

更新日期：1976-01-01 00:00:00

abstract：:Scrapie brain homogenate was mixed with mouse peritoneal macrophages in vitro. After 2 h of incubation at 37 degrees, a portion of the scrapie infectivity was associated with macrophages. In contrast, very little infectivity was associated with kidney cells that had been exposed to scrapie brain homogenate. After incu...

journal_title：Intervirology

authors： Carp RI,Callahan SM

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...

journal_title：Intervirology

authors： Zheng L,Yang Y,Guocai L,Pauza CD,Salvato MS

更新日期：2007-01-01 00:00:00

abstract：:By a combination of PCR and direct-cycle sequencing using consensus primers, we analyzed approximately 400-bp fragments within the NS3 genes of twenty-one dengue virus type 3 strains isolated from five neighboring Southeast Asian countries at different time intervals from 1956 to 1992. The majority of base disparities...

journal_title：Intervirology

authors： Chow VT,Seah CL,Chan YC

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:To characterize morphological, physicochemical and genomic features of a novel virulent coliphage which was isolated from an engineered Escherichia coli culture and termed engineered E. coli phage (EEP). METHODS AND RESULTS:Electron microscopy revealed that EEP has an icosahedral head (62 nm in diameter) an...

journal_title：Intervirology

authors： Li S,Liu L,Zhu J,Zou L,Li M,Cong Y,Rao X,Hu X,Zhou Y,Chen Z,Hu F

更新日期：2010-01-01 00:00:00