Comparative analysis of NS3 sequences of temporally separated dengue 3 virus strains isolated from southeast Asia.

abstract：OBJECTIVES:Chikungunya virus (CHIKV) is an alphavirus belonging to the Togaviridae family. Alphaviruses cause a chronic non-cytopathic infection in mosquito cells, while they develop a highly cytopathic infection in cells originating from various vertebrates. In this study, we compared the cytopathic effect (CPE) induc...

journal_title：Intervirology

authors： Li YG,Siripanyaphinyo U,Tumkosit U,Noranate N,A-nuegoonpipat A,Tao R,Kurosu T,Ikuta K,Takeda N,Anantapreecha S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Dengue virus is spread in tropical areas of the world and is the causative agent of dengue fever and dengue hemorrhagic fever. It is horizontally transmitted to humans by infected Aedes mosquitoes, but it is also able to be vertically or transovarially transmitted to insect progeny. OBJECTIVE:In this work, ...

journal_title：Intervirology

authors： Günther J,Martínez-Muñoz JP,Pérez-Ishiwara DG,Salas-Benito J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To determine whether liver-derived hepatitis C RNA-containing particles express the E1E2 discontinuous antigenic determinant defined by unique monoclonal antibody (mAb) D32.10 which recognizes three highly conserved segments in E1 (aa297-306) and E2 (aa480-494 and aa613-621) envelope glycoproteins. METHODS:H...

journal_title：Intervirology

authors： Ndongo N,Selliah S,Berthillon P,Raymond VA,Trépo C,Bilodeau M,Petit MA

更新日期：2011-01-01 00:00:00

abstract：:The purpose of our work was to determine if aerosols of Junin virus can infect rhesus macaques and if the disease is the same as that produced by virus inoculated parenterally. The 6 macaques exposed to the virus by aerosol became acutely ill during the 3rd week after exposure, and all died. Three died by day 21, whil...

journal_title：Intervirology

authors： Kenyon RH,McKee KT Jr,Zack PM,Rippy MK,Vogel AP,York C,Meegan J,Crabbs C,Peters CJ

更新日期：1992-01-01 00:00:00

abstract：:Membrane particles possessing receptor activity for influenza virions have been reconstituted following solubilization of human erythrocyte membranes with octylglucoside (OG) and fractionation on a DEAE-cellulose column. Fractions that eluted with 1.5 M NaCl yielded, after removal of OG, reconstituted membrane particl...

journal_title：Intervirology

authors： Baron CB,Blough HA

更新日期：1983-01-01 00:00:00

abstract：:Damage and necrosis of hepatocytes in viral hepatitis C is considered to be immune mediated as in hepatitis B. Hepatocellular necrosis accompanies infiltration of lymphocytes and this feature, called necroinflammation, characterizes all types of viral hepatitis and corresponds to the histological expression of hepatit...

journal_title：Intervirology

authors： Uchida T

更新日期：1994-01-01 00:00:00

abstract：:Human cytomegalovirus (CMV) has devised numerous means of escaping immune surveillance. The CMV genome encodes at least 4 genes involved in downregulating surface expression of HLA class I molecules. In addition, it sequesters CC chemokines, induces Fc receptors, interferes with induction of HLA class II antigens, and...

journal_title：Intervirology

authors： Michelson S

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:To characterize morphological, physicochemical and genomic features of a novel virulent coliphage which was isolated from an engineered Escherichia coli culture and termed engineered E. coli phage (EEP). METHODS AND RESULTS:Electron microscopy revealed that EEP has an icosahedral head (62 nm in diameter) an...

journal_title：Intervirology

authors： Li S,Liu L,Zhu J,Zou L,Li M,Cong Y,Rao X,Hu X,Zhou Y,Chen Z,Hu F

更新日期：2010-01-01 00:00:00

abstract：:Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by int...

journal_title：Intervirology

authors： Li TC,Yoshizaki S,Ami Y,Suzaki Y,Yang T,Takeda N,Takaji W

更新日期：2015-01-01 00:00:00

abstract：:In this article, a statistical score method for comparison of partial genomic regions in their representatives of full-length genome of hepatitis E virus (HEV) for genotyping was developed. The critical values of the statistics for hypothesis testing were generated through Monte Carlo simulations. It was found that fr...

journal_title：Intervirology

authors： Xun P,Chen F,Dong C,Qian G,Lai D,Meng J

更新日期：2007-01-01 00:00:00

abstract：:In order to evaluate the usefulness of cytomegalovirus (CMV) antibody screening during pregnancy, women attending for antenatal care at the Antoine Béclère Hospital (Clamart, France) were prospectively studied during 22 months (1995-1996). Forty-five percent of these women were CMV-seropositive. Twenty suspected or co...

journal_title：Intervirology

authors： Grangeot-Keros L,Simon B,Audibert F,Vial M

更新日期：1998-01-01 00:00:00

abstract：:Human skin fibroblasts have previously been reported to display an age-dependent resistance to infection with coxsackie B4 virus. We have shown that the virus will replicate and produce CPE in human skin fibroblasts regardless of the age of the donor of the cells. The passage history of the virus was found to influenc...

journal_title：Intervirology

authors： Miller M,Harnett GB,Bucens MR

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:The open reading frame 8 (ORF8) within the short unique (U(s)) region of the bovine herpesvirus 1 (BHV-1) genome was predicted to encode a protein with homology to U(s)9 protein of other alpha herpesviruses. The aim of this study is to identify the protein encoded by the U(s) ORF8 and to examine the effect of...

journal_title：Intervirology

authors： Nakamichi K,Matsumoto Y,Tohya Y,Otsuka H

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Dengue fever (DF), one of the main emerging virus diseases, also increases in German travellers, due to the increasing number of travellers to tropical regions. METHODS:We determined antibodies against DF virus in a group (n = 149) of long-distance travellers in order to evaluate the risk of acquiring DF. S...

journal_title：Intervirology

authors： Allwinn R,Hofknecht N,Doerr HW

更新日期：2008-01-01 00:00:00

abstract：:The regulatory regions for transcription and replication of several hepatitis B virus (HBV) genomes from 19 patients having various forms of HBV infection were sequenced. Predominant mutations were found to occur naturally in nucleotide positions 1762 (A to T) and 1764 (G to A) in chronic hepatitis patients and in asy...

journal_title：Intervirology

authors： Nishizono A,Hiraga M,Kohno K,Sonoda YT,Terao H,Fujioka T,Nasu M,Mifune K

更新日期：1995-01-01 00:00:00

abstract：:Nasal natural killer (NK)/T cell lymphoma is a peculiar lymphoma with a unique immunophenotype. Etiologically, in 1990, the authors first demonstrated the presence of Epstein-Barr virus (EBV) genomes and their products in this lymphoma. EBV-specific cytotoxic T lymphocytes (CTL) are very important in controlling the l...

journal_title：Intervirology

authors： Nagamine M,Kishibe K,Takahara M,Nagato T,Ishii H,Bandoh N,Ogino T,Harabuchi Y

更新日期：2007-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV), like all herpesviruses, persists in the host after primary infection, with reactivation often occurring as a result of immunosuppression. The lack of a model system has made analysis of HCMV latency and reactivation difficult. However, the ability to analyse which specific cell types in v...

journal_title：Intervirology

authors： Sinclair J,Sissons P

更新日期：1996-01-01 00:00:00

abstract：:The genetic relationship between two enteroviruses causing the acute hemorrhagic conjunctivitis (AHC) syndrome was examined by the RNA-RNA hybridization technique. Nucleotide sequence homology between the J670/71 strain of enterovirus type 70 (EV70) and the EH 24/70 strain of Singapore epidemic conjunctivitis (SEC) vi...

journal_title：Intervirology

authors： Natori K,Yamazaki S,Miyamura K,Kono R

更新日期：1984-01-01 00:00:00

abstract：:The PLC/PRF/5 human hepatoma cell line producing hepatitis B surface antigen (HBsAg) was studied to determine whether infectious hepatitis B virus (HBV) was also being produced. 2 chimpanzees with no previous exposure to HBV and no serologic markers of past or active HBV infection were inoculated intravenously with 50...

journal_title：Intervirology

authors： Tabor E,Copeland JA,Mann GF,Howard CR,Skelly J,Snoy P,Zuckerman AJ,Gerety RJ

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To understand the autoimmunity associated with chronic hepatitis C (CHC), we investigated autoantibodies (autoAbs) to CD69. METHODS:With this aim, we tested the reactivity of serum samples from patients with CHC and asymptomatic carriers of hepatitis C virus (HCV), as well as from patients with chronic hepat...

journal_title：Intervirology

authors： Okamoto N,Yotsuyanagi H,Ooka S,Matsui T,Suzuki Kurokawa M,Suzuki M,Iino S,Nishioka K,Kato T

更新日期：2003-01-01 00:00:00

abstract：:The aim of the study was to determine the prevalence of drug resistance of HIV-1 in pediatric patients from Istanbul, Turkey. Genotypic drug resistance testing revealed transmission of drug resistance from mother to child in 20%. Due to rising numbers of children with HIV-1, baseline resistance testing is recommended ...

journal_title：Intervirology

authors： Yoldaş O,Ağaçfidan A,Lübke N,Somer A,Hançerli S,Verheyen J,Kaiser R,Akgül B

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the mutational patterns on the pol gene of the main HIV-1 strain archived in cell genome of 10 chronically infected men according to their clinical and therapeutic history. The genotyping resistance profiles were compared between the first blood plasma available at the time of HIV diagnosis and re...

journal_title：Intervirology

authors： Depincé AE,Dussert E,Vergnon-Miszczycha D,Keita A,Pillet S,Botelho-Nevers E,Frésard A,Gagneux-Brunon A,Lucht FR,Roblin X,Pozzetto B,Paul S,Bourlet T

更新日期：2016-01-01 00:00:00

abstract：:The complete sequence of the single-stranded, positive-sense RNA genome of pea stem necrosis virus (PSNV) has been determined. The 4,048-nucleotide genome contains five open reading frames (ORFs). The 5'-proximal ORF encodes a 25-kD protein (p25). If the amber termination codon is read through, the ORF produces a read...

journal_title：Intervirology

authors： Suzuki S,Hase S,Takahashi H,Ikegami M

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to determine the hepatitis B virus (HBV) genotypes in hepatitis delta virus (HDV) RNA-positive patients and to characterize the HBV nucleotide sequences that may be found on a distant island of Japan. METHODS:This study included three patients with chronic hepatitis who were posi...

journal_title：Intervirology

authors： Moriyama M,Taira M,Matsumura H,Aoki H,Mikuni M,Kaneko M,Shioda A,Iwaguchi K,Arai S,Ichijima S,Iwasaki H,Tanaka N,Abe K,Arakawa Y

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To screen and identify cellular proteins binding to the core region of hepatitis C virus (HCV) RNA genome. METHODS:The plasmid pHCV core was constructed to generate in vitro transcripts of the core region of HCV RNA genome. Ultraviolet (UV) cross-linking experiment and competition analysis were performed to ...

journal_title：Intervirology

authors： Su HX,Xu DZ,Zhang YH,Men K,Zhao XN,Li D,Zhang L,Zhang JX,Yan YP

更新日期：2007-01-01 00:00:00

abstract：:Three independently isolated herpes simplex virus type 1 recombinant viruses containing a deletion of approximately 14 kilobase pairs, representing greater than 95% of the internal repeat DNA sequences, were analyzed for their pathogenicity in mice. The recombinant viruses were found to be avirulent, exhibiting drasti...

journal_title：Intervirology

authors： Jenkins FJ,Martin JR

更新日期：1990-01-01 00:00:00

abstract：:In chicken cells infected by Sindbis virus and exposed to a variety of membrane-active compounds, virus release was inhibited. In infected cells exposed to antiserum directed against the virion glycoproteins E1 or E2, retinol, cortisone, Pb++ or insulin, the processing of two Sindbis virus precursor polypeptides which...

journal_title：Intervirology

authors： Scupham RK,Sagik BP,Bose HR Jr

更新日期：1979-01-01 00:00:00

abstract：:To evaluate the diagnostic value of nucleic-acid-sequence-based amplification (NASBA) for the detection of cytomegalovirus (CMV) infection in transplant recipients, we compared immediate early 1 (IE1) and late pp67 mRNA detection by NASBA with the antigenemia assay, PCR and viral culture in 72 renal transplant (RTx) r...

journal_title：Intervirology

authors： Goossens VJ,Blok MJ,Christiaans MH,van Hooff JP,Sillekens P,Höckerstedt K,Lautenschlager I,Middeldorp JM,Bruggeman CA

更新日期：1999-01-01 00:00:00

abstract：:Despite the existence for some time of effective prophylactic vaccines, hepatitis B virus (HBV) infection remains an important global concern. Improvements on existing vaccines could be beneficial, especially in situations where it is desirable or necessary to induce protective immunity more rapidly or with fewer dose...

journal_title：Intervirology

authors： Payette PJ,Ma X,Weeratna RD,McCluskie MJ,Shapiro M,Engle RE,Davis HL,Purcell RH

更新日期：2006-01-01 00:00:00

abstract：:Early hepatocellular carcinoma (HCC) as defined by the Liver Cancer Study Group of Japan would correspond to high-grade dysplastic nodules with small foci of HCC in the majority of cases, using the classification system proposed by the International Working Party. A large number of early HCCs were revealed to be hypo-...

journal_title：Intervirology

authors： Takayasu K,Muramatsu Y,Mizuguchi Y,Moriyama N,Ojima H

更新日期：2004-01-01 00:00:00