Abstract:
:Influenza PR8 particles resulting from strong treatment with caseinase C are spikeless, devoid of neuraminidase and hemagglutinin 1 and 2 glycopeptides, and contain a Schiff-negative polypeptide of about 13,000 molecular weight which exists as traces in intact virions. Their M-protein polypeptide content is reduced to 50% of its original value, but there is no evidence of particle disruption nor of lipid release. They fix complement in the presence of both anti-M-protein antiserum and antiserum raised against a host polysaccharide. During exposure to caseinase C, an antigen is unmasked. It is type-specific and its identity with the M-protein is discussed.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Reginster M,Rentier B,Dierickx Ldoi
10.1159/000149478subject
Has Abstractpub_date
1975-01-01 00:00:00pages
239-48issue
4-5eissn
0300-5526issn
1423-0100journal_volume
6pub_type
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