Dendritic cells and chronic hepatitis virus carriers.

abstract：:Monoclonal antibodies were used to study measles virus (Hallé strain) infections. The distribution of virus antigens in acutely and persistently infected cells was examined by immunofluorescence, and the synthesis of the virus polypeptides in acutely infected cells was measured after immunoprecipitation and analysis i...

journal_title：Intervirology

authors： Giraudon P,Gerald C,Wild TF

更新日期：1984-01-01 00:00:00

abstract：:Purified Junin virus was disrupted by nonionic detergent treatment (Triton X-100), and subviral components were separated by ultracentrifugation. Only the soluble fraction, containing all of the major glycoprotein (mol.wt. 38,000), induced the formation of neutralizing antibodies in laboratory animals and protected th...

journal_title：Intervirology

authors： Cresta B,Padula P,de Martinez Segovia M

更新日期：1980-01-01 00:00:00

abstract：:The kinetics of Aleutian disease virus (ADV) replication in mink lymphocytes was followed by the analysis of virus-specific antigens, infectious virus, and viral DNA. Stimulation with pokeweed mitogen (PWM; 20 micrograms/ml) increased the synthesis of ADV DNA in cultivated cells of the B-cell fraction. Maximum virus t...

journal_title：Intervirology

authors： Kaaden OR,Haas L,Löchelt M,Roth S

更新日期：1986-01-01 00:00:00

abstract：:We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

journal_title：Intervirology

authors： Simard C,LaBoissière S,Séguin C,Trudel M

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:The genetic barrier for the evolution of integrase inhibitors (INIs) including raltegravir (RAL), elvitegravir (EVG), and dolutegravir (DTG) resistance was compared between HIV-1 subtypes CRF01_AE and B. METHODS:Analysis of 66 substitutions associated with INI resistance at 41 amino acid positions in 144 nuc...

journal_title：Intervirology

authors： Nguyen HL,Ruxrungtham K,Delaugerre C

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...

journal_title：Intervirology

authors： Zheng L,Yang Y,Guocai L,Pauza CD,Salvato MS

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin molecule of influenza virus is considered as an ideal model to study biological processes as well as the effect of glycosylation on the function of glycoproteins. OBJECTIVES:The large subunit of the influenza virus A/New Caledonia/20/99 (H1N1) hemagglutinin (HA1) was expressed in recombina...

journal_title：Intervirology

authors： Farahmand B,Khodabandeh M,Mahboudi F,Fotouhi F,Saleh M,Barkhordari F,Tabatabaian M,Nasab FP,Kheiri MT

更新日期：2012-01-01 00:00:00

abstract：:Five distinct antigenic sites recognized by cytotoxic T lymphocytes in H-2b mice have been identified on simian virus 40 (SV40) T antigen. Cocultivation of SV40-transformed cells with cytotoxic T lymphocyte (CTL) clones specific for epitopes I-IV results in the selection of variants which show a loss of either epitope...

journal_title：Intervirology

authors： Tanaka Y,Tevethia SS

更新日期：1990-01-01 00:00:00

abstract：:An RNA virus was isolated from Trichoplusia ni larvae infected with inoculum of the baculovirus of Autographa californica. Physicochemical characterization has revealed a 35-nm virus with a density in CsCl of 1.3 g/cm3 and a sedimentation coefficient of 200S. The virus consisted of 10--15% single-stranded RNA with an ...

journal_title：Intervirology

authors： Morris TJ,Hess RT,Pinnock DE

更新日期：1979-01-01 00:00:00

abstract：:Early hepatocellular carcinoma (HCC) as defined by the Liver Cancer Study Group of Japan would correspond to high-grade dysplastic nodules with small foci of HCC in the majority of cases, using the classification system proposed by the International Working Party. A large number of early HCCs were revealed to be hypo-...

journal_title：Intervirology

authors： Takayasu K,Muramatsu Y,Mizuguchi Y,Moriyama N,Ojima H

更新日期：2004-01-01 00:00:00

abstract：:Healthy common marmosets from two separate colonies, one in England and one in France, were found to have antibodies cross-reacting with Epstein-Barr virus structural antigens (EBV-VCA). All seropositive animals were at least 2 years old. Experimental EBV infection of marmosets of different ages led to seroconversion ...

journal_title：Intervirology

authors： de-Thé G,Dubouch P,Fontaine C,Wedderburn N,Carter RL,Edwards MB,Cohen B

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:Pandemic viral infections as emerging infectious diseases are of a great global concern. However, for some viruses, particular strains are endemic to specific areas and can be genetically distinguished from strains in other regions. In contrast, for some other viruses, genetically similar strains can spread a...

journal_title：Intervirology

authors： Furuse Y,Suzuki A,Kamigaki T,Mpolya EA,Khandaker I,Oshitani H

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:In this study we established a mouse brain injection system to detect infectious dengue-2 virus produced from the full-length RNA transcripts. METHODS:In vitro transcription was used to synthesize full-length dengue-2 virus RNA from the plasmid pRS424FLDEN2NGC, which was intracerebrally injected into the 6-d...

journal_title：Intervirology

authors： Lee YR,Huang KJ,Lei HY,Chen SH,Lin YS,Yeh TM,Liu HS

更新日期：2005-01-01 00:00:00

abstract：:Coinfections with hepatitis B virus (HBV) and HIV are very frequent. Although HBV is a DNA virus, it replicates via reverse transcription like HIV. Structural similarities between the enzymatic pocket of the HBV DNA polymerase and HIV-1 reverse transcriptase are the basis that certain drugs inhibit both enzymes and th...

journal_title：Intervirology

authors： Gürtler LG

更新日期：2014-01-01 00:00:00

abstract：:Despite the significant medical advances which have taken place in the last decades, acute diarrhoea cases remain a public health issue of major significance, with gastroenteritis agents being associated with severe symptoms in adults and high morbidity in infants and children. Regarding rotaviruses, while children ar...

journal_title：Intervirology

authors： Vontas A,Hadjicristodoulou C,Krikelis V,Petinaki E

更新日期：2019-01-01 00:00:00

abstract：:Analysis of translation products synthesized in vitro in the presence of a mixture of brome mosaic virus (BMV) RNAs 1, 2, 3, and 4 usually shows a predominance of coat protein, coded by RNA4. The proportion of products directed by RNAs 1 and 2 decreased at saturating concentrations of BMV RNA and in the presence of 7-...

journal_title：Intervirology

authors： Pyne JW,Hall TC

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Genome-wide sequences of hepatitis B virus strain associated with type B fulminant hepatitis have not been compared with those of acute self-limited hepatitis. We carried out full-length sequencing analysis of viral strains derived from patients with type B acute liver injury. METHODS:Nine acute self-limited...

journal_title：Intervirology

authors： Kanada A,Takehara T,Ohkawa K,Tatsumi T,Sakamori R,Yamaguchi S,Uemura A,Kohga K,Sasakawa A,Hikita H,Hijioka T,Katayama K,Deguchi M,Kagita M,Kanto T,Hiramatsu N,Hayashi N

更新日期：2007-01-01 00:00:00

abstract：:Methods and models for analytical and quantitative researches on the evolution of hepatitis viruses using nucleotide sequences and amino acids of hepatitis viruses are described. Methods for the calculation of evolutionary rates and the construction of molecular evolutionary trees, especially by estimating the number ...

journal_title：Intervirology

authors： Mizokami M,Orito E

更新日期：1999-01-01 00:00:00

abstract：:Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by int...

journal_title：Intervirology

authors： Li TC,Yoshizaki S,Ami Y,Suzaki Y,Yang T,Takeda N,Takaji W

更新日期：2015-01-01 00:00:00

abstract：:The members of the viral family Hepadnaviridae comprise one of the smallest enveloped DNA viruses and cause acute and chronic infections in mammals and birds, leading to large virus and antigen loads in the blood. They have a restricted host range and depend on differentiated hepatocytes for replication. Hepatitis B v...

journal_title：Intervirology

authors： Glebe D,König A

更新日期：2014-01-01 00:00:00

abstract：:Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antige...

journal_title：Intervirology

authors： Norrild B,Vestergaard BF

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:We studied the ability of human cytomegalovirus (HCMV) to infect peripheral blood mononuclear cells (PBMC) pretreated with or without Th2-cytokine interleukin-4 (IL-4) in vitro. METHODS:Adherent cells and nonadherent cells were obtained from PBMC. We inoculated these cells with HCMV at concentrations ranging...

journal_title：Intervirology

authors： Kitajima H,Okubo Y,Honda J,Yonemitsu J,Yoshida N,Fumimori T,Oizumi K

更新日期：2001-01-01 00:00:00

abstract：:Despite the existence for some time of effective prophylactic vaccines, hepatitis B virus (HBV) infection remains an important global concern. Improvements on existing vaccines could be beneficial, especially in situations where it is desirable or necessary to induce protective immunity more rapidly or with fewer dose...

journal_title：Intervirology

authors： Payette PJ,Ma X,Weeratna RD,McCluskie MJ,Shapiro M,Engle RE,Davis HL,Purcell RH

更新日期：2006-01-01 00:00:00

abstract：:The species concept seems to be inescapably based on the occurrence, in a population, of regular genetic interchange which leads to the formation of common gene pools and on the presence of barriers to interchange which distinguish one gene pool from another. Present knowledge indicates that some types of viruses (e.g...

journal_title：Intervirology

authors： Milne RG

更新日期：1985-01-01 00:00:00

abstract：:Examination of thin sections from the cerebral cortex of scrapie-infected hamster brains revealed characteristic circular 26-30 nm diameter tubulofilamentous particles, identical to those previously described in both experimentally induced scrapie in mice, hamsters and natural scrapie of sheep, bovine spongiform encep...

journal_title：Intervirology

authors： Narang HK

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Arboviruses co-circulating within a population that are transmitted by the same vector have the potential to cause coinfections. Coinfections with dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus (CHIKV) have been occurring in Brazil, but it is not well-understood how human responses vary during...

journal_title：Intervirology

authors： Sánchez-Arcila JC,Badolato-Correa J,de Souza TMA,Paiva IA,Barbosa LS,Nunes PCG,Lima MDRQ,Dos Santos FB,Damasco PV,da Cunha RV,Azeredo EL,de Oliveira-Pinto LM

更新日期：2020-01-01 00:00:00

abstract：:By 48 h postinfection, 40--80% of SV40-infected CV-1 cells have undergone irreversible injury as indicated by trypan blue staining. Nevertheless, at this time the lysosomes of these cells appear as discrete structures after vital staining with either acridine orange or neutral red. Lysosomes, vitally stained with neut...

journal_title：Intervirology

authors： Einck KH,Norkin LC

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:To understand the autoimmunity associated with chronic hepatitis C (CHC), we investigated autoantibodies (autoAbs) to CD69. METHODS:With this aim, we tested the reactivity of serum samples from patients with CHC and asymptomatic carriers of hepatitis C virus (HCV), as well as from patients with chronic hepat...

journal_title：Intervirology

authors： Okamoto N,Yotsuyanagi H,Ooka S,Matsui T,Suzuki Kurokawa M,Suzuki M,Iino S,Nishioka K,Kato T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:In Zimbabwe, cervical cancer is screened through cytology and visual inspection with acetic acid and cervicography (VIAC). The effectiveness of these methods can be increased if complemented by a human papillomavirus DNA detection tool since most cervical cancer cases are caused by persistent infection ...

journal_title：Intervirology

authors： Marembo T,Dube Mandishora R,Borok M

更新日期：2019-01-01 00:00:00

abstract：:Studies of human papillomavirus (HPV) infection are hampered by the lack of an adequate culture system. The athymic mouse xenograft system permits propagation of HPV, but only a few HPV types have been grown in this manner. To produce an oncogenic type for studies of HPV pathogenesis, a condylomata acuminata lesion fr...

journal_title：Intervirology

authors： Bryan JT,Tekchandani J,Schroeder JM,Brown DR

更新日期：2000-01-01 00:00:00