Genetic barrier to the development of resistance to integrase inhibitors in HIV-1 subtypes CRF01_AE and B.

abstract：:Nasal natural killer (NK)/T cell lymphoma is a peculiar lymphoma with a unique immunophenotype. Etiologically, in 1990, the authors first demonstrated the presence of Epstein-Barr virus (EBV) genomes and their products in this lymphoma. EBV-specific cytotoxic T lymphocytes (CTL) are very important in controlling the l...

journal_title：Intervirology

authors： Nagamine M,Kishibe K,Takahara M,Nagato T,Ishii H,Bandoh N,Ogino T,Harabuchi Y

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Many efforts are currently focused on functional treatment of the hepatitis B virus (HBV). This can be done by suppressing the secretion of HBV surface antigen (HBsAg). Scientific communities are very interested in natural products in that respect. OBJECTIVE:Use of root extract of Havachoobe (Onosma dichroa...

journal_title：Intervirology

authors： Mohebbi A,Azadi F,Hashemi MM,Askari FS,Razzaghi N

更新日期：2020-12-15 00:00:00

abstract：BACKGROUND/AIMS:The nucleo-cytoplasmic large DNA viruses (NCLDV) constitute an apparently monophyletic group that consists of 6 families of viruses infecting a broad variety of eukaryotes. A comprehensive genome comparison and maximum-likelihood reconstruction of NCLDV evolution reveal a set of approximately 50 conserv...

journal_title：Intervirology

authors： Koonin EV,Yutin N

更新日期：2010-01-01 00:00:00

abstract：:The amino acid composition (AAC) of the coat proteins (CPs) of 126 plant viruses or strains were analyzed by stepwise discriminant analysis. The criteria chosen for discrimination were: the structure of virus particles (3 clusters); the mode of of transmission of the viruses (6 clusters); and the grouping of viruses a...

journal_title：Intervirology

authors： Fauquet C,Dejardin J,Thouvenel JC

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to investigate the molecular mechanism of hepatocellular carcinoma (HCC) development induced by hepatitis B virus X protein (HBx). METHODS:We previously established a H7402-X cell line that constitutively expresses HBx protein. In the present study, H7402-X gene expression profiles a...

journal_title：Intervirology

authors： Ye L,Dong N,Wang Q,Xu Z,Cai N,Wang H,Zhang X

更新日期：2008-01-01 00:00:00

abstract：:A whitefly-transmitted virus from Venezuela, potato yellow mosaic virus, has been propagated, isolated and characterized as a member of the Geminivirus group. The virus was transmitted to several species of Nicotiana and to Petunia hybrida by mechanical inoculation, and to potato and tomato plants by grafting. Purifie...

journal_title：Intervirology

authors： Roberts EJ,Buck KW,Coutts RH

更新日期：1988-01-01 00:00:00

abstract：AIMS:The aim of the present study is the preliminary characterization of an El Tor vibriophage M4 (ATCC 51352-B4). METHODS:We studied the growth characteristics and sustainability of this phage under various stresses like temperature, pH, and UV. The phage morphology and phage genome were also examined using electron ...

journal_title：Intervirology

authors： Das S,Ghosh AN

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Transmission of HIV-1 and diagnosis of infection in hospitals and public health settings remains a worldwide concern. HIV-1 detection is sometimes not possible using current commercial assays, probably due to mismatches between the selected primers and probes. METHODS:By screening primers and probes, we deve...

journal_title：Intervirology

authors： Huang J,Yang CM,Wang LN,Meng S,Deng W,Li JM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:The present study was launched to systematically characterize the molecular genotypes and quantitative serological biomarkers during the natural course of chronic hepatitis B (CHB) infection in a patient population from Chongqing, China. METHODS:A total of 140 patients were enrolled and grouped accordi...

journal_title：Intervirology

authors： Xiang Y,Huang S,Xia J,Ye D,Chen P,Zhang L

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:To explore the host transcription factor E2F-1 and/or any mechanisms that may support viral entry and its effect on the HSV-1 production in anti-CD3-activated Jurkat cells. METHODS:The expressions of ICP4, HVEM and E2F-1 were studied using reverse transcription-PCR and Western blot. HSV-1 production was det...

journal_title：Intervirology

authors： Bhattarakosol P,Donchai P

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Mycosis fungoides (MF) is the most frequent form of cutaneous T cell lymphoma (CTCL). Human T cell leukemia virus type 1 (HTLV-1) involvement in MF progression is a matter of debate. The goal of the investigation was to search for HTLV-1 markers in a group of MF patients from a nonendemic area to HTLV-1. MAT...

journal_title：Intervirology

authors： Morozov VA,Syrtsev AV,Ellerbrok H,Nikolaeva EV,Bavykin AS,Pauli G

更新日期：2005-01-01 00:00:00

abstract：:Rauscher murine leukemia virus (RLV) infection of adult mice results in splenomegaly that is proportional to the virus titer. We have used this model to study the therapy of chronic viremia as well as chemoprophylaxis after viral exposure, both with single agents and with combination therapy. We showed that prompt ini...

journal_title：Intervirology

authors： Ruprecht RM

更新日期：1989-01-01 00:00:00

abstract：:Marek's disease herpesvirus (MDHV) isolated from chickens free of naturally occurring avian leukosis virus (ALV) infection produced characteristic foci in both chicken embryo fibroblast (CEF) and chicken kidney cell (CKC) cultures. MDHV-A, which was extracted from the feather follicle epithelium of chickens naturally ...

journal_title：Intervirology

authors： Campbell WF,Kufe DW,Peters WP,Spiegelman S,Frankel JW

更新日期：1978-01-01 00:00:00

abstract：:In order to assess the risk of transmission of viral diseases during floods, the viral burden in flooded areas of the city of Dresden (Germany) in August 2002 was investigated. Water samples were collected from 9 sampling sites and tested for the presence of 11 enteric viral pathogens. As a control, water samples from...

journal_title：Intervirology

authors： Rohayem J,Dumke R,Jaeger K,Schröter-Bobsin U,Mogel M,Kruse A,Jacobs E,Rethwilm A

更新日期：2006-01-01 00:00:00

abstract：:The ability to discriminate between herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) infections by serological means is of increasing importance for clinical virological diagnostics. HSV type-specific serology has a number of applications, e.g. to guide duration and dosage of antiviral therapy, to allow for string...

journal_title：Intervirology

authors： Bergström T,Trybala E

更新日期：1996-01-01 00:00:00

abstract：:Virus-associated DNA polymerase activity has recently been proposed for the detection of human cytomegalovirus (HCMV) in urine, a method that should allow rapid and quantitative determination of the viral load. In this report, the virus-associated DNA polymerase activity recovered from the urine of a group of patients...

journal_title：Intervirology

authors： Marcello A,Pisoni G,Pizzighella S,Palù G

更新日期：1996-01-01 00:00:00

abstract：:The aligned restriction endonuclease maps of three sequenced maize streak virus isolates, three restriction-mapped southern African maize streak virus isolates, and two other sequenced geminiviruses were used as a means of calculating the sequence divergence between these viruses. The degree of divergence was used to ...

journal_title：Intervirology

authors： Kirby R,Clarke BA,Rybicki EP

更新日期：1989-01-01 00:00:00

abstract：:Five distinct antigenic sites recognized by cytotoxic T lymphocytes in H-2b mice have been identified on simian virus 40 (SV40) T antigen. Cocultivation of SV40-transformed cells with cytotoxic T lymphocyte (CTL) clones specific for epitopes I-IV results in the selection of variants which show a loss of either epitope...

journal_title：Intervirology

authors： Tanaka Y,Tevethia SS

更新日期：1990-01-01 00:00:00

abstract：:We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

journal_title：Intervirology

authors： Simard C,LaBoissière S,Séguin C,Trudel M

更新日期：1991-01-01 00:00:00

abstract：:Hybrid recombinant plasmids were constructed; they were composed of the herpes simplex virus type 2 (HSV2) thymidine kinase (tk) gene and DNA sequences of HSV2 that have been reported to induce morphological and/or oncogenic transformation of rodent cells in culture. Several plasmids were made in two versions, with or...

journal_title：Intervirology

authors： van den Berg FM,van Amstel PJ,Walboomers JM

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...

journal_title：Intervirology

authors： Zheng L,Yang Y,Guocai L,Pauza CD,Salvato MS

更新日期：2007-01-01 00:00:00

abstract：:The complex etiology of mucosal disease of cattle has been unravelled by experimental reproduction of the fatal syndrome, thereby validating Koch's postulates. The causal virus, bovine virus diarrhea virus (BVDV), has two biotypes, noncytopathogenic and cytopathogenic; the former can infect the early bovine fetus, ind...

journal_title：Intervirology

authors： Brownlie J,Clarke MC

更新日期：1993-01-01 00:00:00

abstract：:Two closely related viruses were isolated from the blood of bovines near Darwin, Northern Territory, Australia. When studies of virus morphology indicated that these were rhabdoviruses, serologic studies were done. These isolates are closely related or identical and are related to, but distinct from, the rabies-relate...

journal_title：Intervirology

authors： Gard GP,Melville LF,Calisher CH,Karabatsos N

更新日期：1992-01-01 00:00:00

abstract：:The 20-nm noninfectious empty envelope particles carrying the hepatitis B surface antigen are secreted in large excess from hepatocytes during a hepatitis B infection. Similar particles produced in cell lines or yeast are an efficient vaccine against hepatitis B virus. We have analyzed the assembly of 20-nm particles ...

journal_title：Intervirology

authors： Prange R,Mangold CM,Hilfrich R,Streeck RE

更新日期：1995-01-01 00:00:00

abstract：:There are two major requirements for potyvirus taxonomy; group-specific criteria and criteria which discriminate between distinct viruses and strains. This review discusses the relative merits in potyvirus taxonomy of molecular parameters, such as gene sequence data, nucleic acid hybridization, coat protein sequence d...

journal_title：Intervirology

authors： Ward CW,Shukla DD

更新日期：1991-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) induces chronic liver disease in hosts which can eventually progresses to liver cirrhosis and hepatocellular carcinoma. However, progression of liver disease is slower in patients with persistently normal levels of alanine aminotransferase (ALT) than in those with active hepatitis. Although dis...

journal_title：Intervirology

authors： Kanto T,Inoue M,Miyazaki M,Itose I,Miyatake H,Sakakibara M,Yakushijin T,Kaimori A,Oki C,Hiramatsu N,Kasahara A,Hayashi N

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin molecule of influenza virus is considered as an ideal model to study biological processes as well as the effect of glycosylation on the function of glycoproteins. OBJECTIVES:The large subunit of the influenza virus A/New Caledonia/20/99 (H1N1) hemagglutinin (HA1) was expressed in recombina...

journal_title：Intervirology

authors： Farahmand B,Khodabandeh M,Mahboudi F,Fotouhi F,Saleh M,Barkhordari F,Tabatabaian M,Nasab FP,Kheiri MT

更新日期：2012-01-01 00:00:00

abstract：:To identify specific environmental, viral, and genetic risk factors for hepatocellular carcinoma (HCC) and the interaction of such factors, we are conducting a prospective study in a high-incidence area of China. Questionnaires were completed and biosamples collected by 60,984 men ages 30-64 years, at study entry. Wit...

journal_title：Intervirology

authors： London WT,Evans AA,McGlynn K,Buetow K,An P,Gao L,Lustbader E,Ross E,Chen G,Shen F

更新日期：1995-01-01 00:00:00

abstract：:Membrane particles possessing receptor activity for influenza virions have been reconstituted following solubilization of human erythrocyte membranes with octylglucoside (OG) and fractionation on a DEAE-cellulose column. Fractions that eluted with 1.5 M NaCl yielded, after removal of OG, reconstituted membrane particl...

journal_title：Intervirology

authors： Baron CB,Blough HA

更新日期：1983-01-01 00:00:00

abstract：:Previous reports documented the recovery of a DNA virus from a patient with posttransfusion non-A-G hepatitis and named TT virus (TTV). Although the virus was initially detected as a causative agent of hepatitis, there is doubt about its pathogenicity. The aim of this study was to clarify the relationship between TTV ...

journal_title：Intervirology

authors： Suzuki F,Chayama K,Tsubota A,Akuta N,Someya T,Kobayashi M,Suzuki Y,Saitoh S,Arase Y,Ikeda K,Kumada H

更新日期：2001-01-01 00:00:00