Kinetics of human antibody responses to primary genital herpes simplex virus infection.

Abstract:

:5 patients with primary genital herpes simplex virus (HSV) infection were studied prospectively for the production of serum antibody reactivity as measured by the virus micro-neutralization test (NT), micro-solid phase radioimmunometric assay (micro-SPRIA), and antibody-dependent cellular-cytotoxic (ADCC) test. ADCC antibody was detected before reactivity measured by either NT or micro-SPRIA in 2 of the patients. A 3rd patient failed to produce neutralizing antibody, whereas specific activity was detected by the other two methods. In 2 other patients a good correlation was observed for development of antibody by all three methods. There were several discordant results in the kinetics of production of antibody detected by these assays, suggesting that not all individuals produce similar types of antiviral antibody.

journal_name

Intervirology

journal_title

Intervirology

authors

Kohl S,Adam E,Matson DO,Kaufman RH,Dreesman GR

doi

10.1159/000149320

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

164-8

issue

3

eissn

0300-5526

issn

1423-0100

journal_volume

18

pub_type

杂志文章
  • Growth characteristics of acute hemorrhagic conjunctivitis (AHC) virus in monkey kidney cells. II. Temperature sensitivity of the isolates obtained at various epidemic areas.

    abstract::Acute hemorrhagic conjunctivitis (AHC) virus strains isolated in eight different areas during epidemics of AHC were tested for the reproductive capacity at 33, 37 and 39 degrees. All of the 25 strains tested grew better at 33 degrees but restrictively at 39 degrees. The degree of temperature sensitivity varied slightl...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149952

    authors: Miyamura K,Sasagawa A,Tajiri E,Kono R

    更新日期:1976-01-01 00:00:00

  • Papillomavirus-like particles for serology and vaccine development.

    abstract::Genital infection with high-risk human papillomaviruses (HPV) has been etiologically linked with the development of cervical and other anogenital cancers. There is therefore a need for an effective HPV vaccine with the potential to significantly reduce the burden of more than half a million new cervical cancer cases i...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150475

    authors: Kirnbauer R

    更新日期:1996-01-01 00:00:00

  • Electron microscopic study of persistent dengue virus infection: analysis using a cell line persistently infected with Dengue-2 virus.

    abstract::We investigated persistent infection of Epstein-Barr virus (EBV)-transformed lymphoblastoid cells with dengue virus using a transmission electron microscope. Most of the infected cells kept an intact morphology with only a few virus particles in the cytoplasm, but without any indication of active viral replication. So...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000050030

    authors: Takasaki T,Takada K,Kurane I

    更新日期:2001-01-01 00:00:00

  • Natural antibodies to EBV-VCA antigens in common marmosets (Callithrix jacchus) and response after EBV inoculation.

    abstract::Healthy common marmosets from two separate colonies, one in England and one in France, were found to have antibodies cross-reacting with Epstein-Barr virus structural antigens (EBV-VCA). All seropositive animals were at least 2 years old. Experimental EBV infection of marmosets of different ages led to seroconversion ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149198

    authors: de-Thé G,Dubouch P,Fontaine C,Wedderburn N,Carter RL,Edwards MB,Cohen B

    更新日期:1980-01-01 00:00:00

  • Influenza virus hemagglutinin: a model for protein N-glycosylation in recombinant Escherichia coli.

    abstract:BACKGROUND:The hemagglutinin molecule of influenza virus is considered as an ideal model to study biological processes as well as the effect of glycosylation on the function of glycoproteins. OBJECTIVES:The large subunit of the influenza virus A/New Caledonia/20/99 (H1N1) hemagglutinin (HA1) was expressed in recombina...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000327784

    authors: Farahmand B,Khodabandeh M,Mahboudi F,Fotouhi F,Saleh M,Barkhordari F,Tabatabaian M,Nasab FP,Kheiri MT

    更新日期:2012-01-01 00:00:00

  • Koolpinyah: a virus related to kotonkan from cattle in northern Australia.

    abstract::Two closely related viruses were isolated from the blood of bovines near Darwin, Northern Territory, Australia. When studies of virus morphology indicated that these were rhabdoviruses, serologic studies were done. These isolates are closely related or identical and are related to, but distinct from, the rabies-relate...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150274

    authors: Gard GP,Melville LF,Calisher CH,Karabatsos N

    更新日期:1992-01-01 00:00:00

  • Clinical, Virological, and Immunological Profiles of DENV, ZIKV, and/or CHIKV-Infected Brazilian Patients.

    abstract:BACKGROUND:Arboviruses co-circulating within a population that are transmitted by the same vector have the potential to cause coinfections. Coinfections with dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus (CHIKV) have been occurring in Brazil, but it is not well-understood how human responses vary during...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000510223

    authors: Sánchez-Arcila JC,Badolato-Correa J,de Souza TMA,Paiva IA,Barbosa LS,Nunes PCG,Lima MDRQ,Dos Santos FB,Damasco PV,da Cunha RV,Azeredo EL,de Oliveira-Pinto LM

    更新日期:2020-01-01 00:00:00

  • Origin and evolution of eukaryotic large nucleo-cytoplasmic DNA viruses.

    abstract:BACKGROUND/AIMS:The nucleo-cytoplasmic large DNA viruses (NCLDV) constitute an apparently monophyletic group that consists of 6 families of viruses infecting a broad variety of eukaryotes. A comprehensive genome comparison and maximum-likelihood reconstruction of NCLDV evolution reveal a set of approximately 50 conserv...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000312913

    authors: Koonin EV,Yutin N

    更新日期:2010-01-01 00:00:00

  • Biochemically silent posttransfusion non-A, non-B hepatitis interferes with superinfection by hepatitis A virus.

    abstract::Superinfection of a silently non-A, non-B (NANB)-infected chimpanzee with hepatitis A virus (HAV) resulted in minimal liver enzyme elevations, lack of detectable HAV in stool, and questionable presence of HAV antigen in liver biopsy specimens obtained during the expected period of virus replication. Our findings indic...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149724

    authors: Bradley DW,Krawczynski K,Humphrey CD,McCaustland KA

    更新日期:1987-01-01 00:00:00

  • HIV Tat protein increases Bcl-2 expression in monocytes which inhibits monocyte apoptosis induced by tumor necrosis factor-alpha-related apoptosis-induced ligand.

    abstract:OBJECTIVE:To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-alpha-related apoptosis-induced ligand (TRAIL). METHODS:Western blot was used to detect Bcl-2 expression in monocytes stimulated by HIV Tat protein, and Annexi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000100565

    authors: Zheng L,Yang Y,Guocai L,Pauza CD,Salvato MS

    更新日期:2007-01-01 00:00:00

  • Leukocyte migration inhibition detects cross-reacting antigens between cells transformed by Epstein-Barr virus (EBV) and EBV-like simian viruses.

    abstract::The leukocyte migration inhibition (LMI) technique was used to measure the T cell-mediated immune response of Epstein-Barr-virus (EBV)-seropositive human donors to antigens associated with B cell lines of simian origin, transformed by simian EBV-like viruses, Herpesvirus papio (HVP), H. pan, H. gorilla and H. pongo. E...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149691

    authors: Szigeti R,Rabin H,Timar L,Klein G

    更新日期:1986-01-01 00:00:00

  • Mixed infection with two tobamoviruses: the formation of particles containing the coat protein messenger RNAs of either virus.

    abstract::Plants mixedly infected with the U2 strain of tobacco mosaic virus (T2MV) and sunnhemp mosaic virus (SHMV) and grown at 35 degrees, yield particles of the same modal lengths (300 and 40 nm) as those found in plants singly infected with SHMV, but not in plants infected with T2MV, which yield only the long particles. At...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149973

    authors: Skotnicki A,Gibbs A,Shaw DC

    更新日期:1976-01-01 00:00:00

  • Historical Discoveries on Viruses in the Environment and Their Impact on Public Health.

    abstract:BACKGROUND:Transmission of many viruses occurs by direct transmission during a close contact between two hosts, or by an indirect transmission through the environment. Several and often interconnected factors, both abiotic and biotic, determine the persistence of these viruses released in the environment, which can las...

    journal_title:Intervirology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1159/000511575

    authors: Labadie T,Batéjat C,Leclercq I,Manuguerra JC

    更新日期:2020-01-01 00:00:00

  • Exposure of Piglets to Enteroviruses Investigated by an Immunoassay Based on the EV-G1 VP4 Peptide.

    abstract:OBJECTIVE:The aim of this study was to investigate the exposure of piglets to enteroviruses-G (EV-G) through the presence of antibodies in their serum. METHODS:Serum samples were obtained from the vena cava of 10 piglets at 9 weeks of age and again 39 days later (day 39). They were tested using an immunoassay based on...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000449058

    authors: Benkahla MA,Sane F,Desailloud R,Hober D

    更新日期:2016-01-01 00:00:00

  • Mutations in the core promoter/enhancer II regions of naturally occurring hepatitis B virus variants and analysis of the effects on transcription activities.

    abstract::The regulatory regions for transcription and replication of several hepatitis B virus (HBV) genomes from 19 patients having various forms of HBV infection were sequenced. Predominant mutations were found to occur naturally in nucleotide positions 1762 (A to T) and 1764 (G to A) in chronic hepatitis patients and in asy...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150453

    authors: Nishizono A,Hiraga M,Kohno K,Sonoda YT,Terao H,Fujioka T,Nasu M,Mifune K

    更新日期:1995-01-01 00:00:00

  • A short hairpin loop-structured oligodeoxynucleotide targeting the virion-associated RNase H of HIV inhibits HIV production in cell culture and in huPBL-SCID mice.

    abstract:BACKGROUND:We have recently demonstrated that an oligodeoxynucleotide (ODN) can enter HIV particles and form a local hybrid at the highly conserved polypurine tract (PPT), the target site of the ODN. This hybrid is recognized by the retrovirus-specific RNase H, which is a virion-associated enzyme. It cleaves the RNA at...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000324544

    authors: Heinrich J,Schols D,Moelling K

    更新日期:2012-01-01 00:00:00

  • Improvement in plaquing methods for the enumeration of anatid herpesvirus (duck plague virus).

    abstract::The Holland strain of anatid herpesvirus (AHV) was 2-to 10-fold more efficiently plaqued under liquid medium or semisolid medium containing methylcellulose than in media containing agar, agarose, or Nobel agar. Virus adsorption was complete in 45 min, with the maximum virus titers obtained under liquid medium at 48 h ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149193

    authors: Attanasio R,Olson R,Johnson JC

    更新日期:1980-01-01 00:00:00

  • Genetic relationship between two enteroviruses causing the acute hemorrhagic conjunctivitis syndrome.

    abstract::The genetic relationship between two enteroviruses causing the acute hemorrhagic conjunctivitis (AHC) syndrome was examined by the RNA-RNA hybridization technique. Nucleotide sequence homology between the J670/71 strain of enterovirus type 70 (EV70) and the EH 24/70 strain of Singapore epidemic conjunctivitis (SEC) vi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149539

    authors: Natori K,Yamazaki S,Miyamura K,Kono R

    更新日期:1984-01-01 00:00:00

  • Impaired function of dendritic cells circulating in patients infected with hepatitis C virus who have persistently normal alanine aminotransferase levels.

    abstract::Hepatitis C virus (HCV) induces chronic liver disease in hosts which can eventually progresses to liver cirrhosis and hepatocellular carcinoma. However, progression of liver disease is slower in patients with persistently normal levels of alanine aminotransferase (ALT) than in those with active hepatitis. Although dis...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000087264

    authors: Kanto T,Inoue M,Miyazaki M,Itose I,Miyatake H,Sakakibara M,Yakushijin T,Kaimori A,Oki C,Hiramatsu N,Kasahara A,Hayashi N

    更新日期:2006-01-01 00:00:00

  • Molecular virology of hepatitis B virus and targets for antiviral intervention.

    abstract::The members of the viral family Hepadnaviridae comprise one of the smallest enveloped DNA viruses and cause acute and chronic infections in mammals and birds, leading to large virus and antigen loads in the blood. They have a restricted host range and depend on differentiated hepatocytes for replication. Hepatitis B v...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000360946

    authors: Glebe D,König A

    更新日期:2014-01-01 00:00:00

  • The genome organization of pea stem necrosis virus and its assignment to the genus Carmovirus.

    abstract::The complete sequence of the single-stranded, positive-sense RNA genome of pea stem necrosis virus (PSNV) has been determined. The 4,048-nucleotide genome contains five open reading frames (ORFs). The 5'-proximal ORF encodes a 25-kD protein (p25). If the amber termination codon is read through, the ORF produces a read...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000065870

    authors: Suzuki S,Hase S,Takahashi H,Ikegami M

    更新日期:2002-01-01 00:00:00

  • Two domains within the early coding region of SV40 involved in the transformation of human fibroblasts.

    abstract::The early gene products of simian virus 40 (SV40) transform human fibroblasts, whereas those of the human papovavirus BK (BKV) do not. The early gene products of both SV40 and BKV transform baby rat kidney cells. SV40-BKV chimerics were constructed which were able to transform baby rat kidney cells. Using the SV40-BKV...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150019

    authors: de Ronde A,Sol CJ,MacDonald ME,Koot M,ter Schegget J,van Strien A,Wouters E,van der Noordaa J

    更新日期:1987-01-01 00:00:00

  • PCR-RFLP-detected human papilloma virus infection in a group of senegalese women attending an STD clinic and identification of a new HPV-68 subtype.

    abstract::Cancer of the cervix is the most common malignant tumor among women in Africa and, in particular, Senegal. Studies of the prevalence of human papilloma virus (HPV) infection in Africa have mainly focused on carcinomas. Data on the presence of the virus in women with normal cervical cytology are scarce. In this study, ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000024981

    authors: Astori G,Beltrame A,Pipan C,Raphenon G,Botta GA

    更新日期:1999-01-01 00:00:00

  • HIV-1 Subtype Diversity and Prevalence of Primary Drug Resistance in a Single-Center Pediatric Cohort in Germany.

    abstract:OBJECTIVES:Data on drug-resistant mutations (DRMs) in HIV-1-infected therapy-naïve children are scarce. The aim of this study was to determine the HIV-1 subtype distribution and the prevalence of DRMs in therapy-naïve HIV-1-infected children who received routine care at the University Hospital Düsseldorf, Düsseldorf, G...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000477811

    authors: Neubert J,Michalsky N,Laws HJ,Borkhardt A,Jensen B,Lübke N

    更新日期:2016-01-01 00:00:00

  • Regulation of infected-cell-specific protein synthesis in SF IPLB-21 cells productively infected with Spodoptera frugiperda multicapsid nuclear polyhedrosis virus.

    abstract::In Spodoptera frugiperda (SF IPLB-21) cells productively infected with S. frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV), we observed the synthesis of infected-cell-specific polypeptides (ICSPs) using the protein synthesis inhibitor cycloheximide (CX) and the DAN synthesis inhibitor cytosine arabinoside (A...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150520

    authors: Liu HS,Bilimoria SL

    更新日期:1997-01-01 00:00:00

  • Contrasting characteristics of Marek's disease herpesvirus isolated from chickens with and without avian leukosis virus infection.

    abstract::Marek's disease herpesvirus (MDHV) isolated from chickens free of naturally occurring avian leukosis virus (ALV) infection produced characteristic foci in both chicken embryo fibroblast (CEF) and chicken kidney cell (CKC) cultures. MDHV-A, which was extracted from the feather follicle epithelium of chickens naturally ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000148963

    authors: Campbell WF,Kufe DW,Peters WP,Spiegelman S,Frankel JW

    更新日期:1978-01-01 00:00:00

  • Barley yellow mosaic virus (BaYMV) and BaYMV-M: two different viruses.

    abstract::Serological and physical properties of isolated particles as well as reactions of barley cultivars after virus inoculation showed that the yellow disease of barley is caused by different viruses. Results summarized in this paper suggest that the European isolates BaYMV-So and BaYMV-NM are closely related to, or identi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150132

    authors: Huth W,Adams MJ

    更新日期:1990-01-01 00:00:00

  • Alphavirus vectors: applications for DNA vaccine production and gene expression.

    abstract::Replication-deficient alphavirus vectors have been developed for efficient high-level transgene expression. The broad host range of alphaviruses has allowed infection of a wide variety of mammalian cell lines and primary cultures. Particularly, G protein-coupled receptors have been expressed at high levels and subject...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000053992

    authors: Lundstrom K

    更新日期:2000-01-01 00:00:00

  • Disappearance of scrapie virus from tissues of the mouse.

    abstract::Examination of newborn mice, inoculated intraperitoneally with high doses of scrapie virus, revealed that the virus could not be reisolated from their tissues after about 1 week following inoculation, until almost 1 year later. The inoculum was rapidly removed and was not detectable, although the animals became latent...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149362

    authors: Hotchin J,Sikora E,Baker F

    更新日期:1983-01-01 00:00:00

  • Nondetection of infectious hepatitis B virus in a human hepatoma cell line producing hepatitis B surface antigen.

    abstract::The PLC/PRF/5 human hepatoma cell line producing hepatitis B surface antigen (HBsAg) was studied to determine whether infectious hepatitis B virus (HBV) was also being produced. 2 chimpanzees with no previous exposure to HBV and no serologic markers of past or active HBV infection were inoculated intravenously with 50...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149217

    authors: Tabor E,Copeland JA,Mann GF,Howard CR,Skelly J,Snoy P,Zuckerman AJ,Gerety RJ

    更新日期:1981-01-01 00:00:00