Prevalence of hepatitis E virus antibodies in patients with chronic hepatitis B and chronic hepatitis C.

Abstract:

OBJECTIVES:To investigate the prevalence of hepatitis E virus (HEV) among patients with chronic hepatitis B and chronic hepatitis C, serum samples were collected between January and December 2004 from patients with chronic hepatitis B and chronic hepatitis C. METHODS:There were 190 adult patients with chronic hepatitis B virus (HBV) and 174 with chronic hepatitis C virus (HCV) infection in the study group. As the control group, a cohort of 178 age- and sex-matched individuals without known liver disease was selected. RESULTS:Anti-HEV IgG antibodies were positive in 26/190 (13.7%) of chronic HBV and 94/174 (54%) of chronic HCV patients. In the control group anti-HEV positivity was 15.7% (28/178). There was no difference in the percentage of chronic HBV patients and control group who were positive for anti-HEV antibody, but the presence of HEV infection was significantly higher in chronic HCV patients. CONCLUSIONS:Our findings suggest that HEV and HCV might share a common route of transmission in our region. We recommend that preventive measures against HEV should be undertaken in chronic HCV patients as superinfection with HEV can cause a more severe pattern of disease in chronic hepatitis patients.

journal_name

Intervirology

journal_title

Intervirology

authors

Bayram A,Eksi F,Mehli M,Sözen E

doi

10.1159/000103916

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

281-6

issue

4

eissn

0300-5526

issn

1423-0100

pii

000103916

journal_volume

50

pub_type

杂志文章
  • The XTrack system: application and advantage.

    abstract::XTrack, a rapid, cost-effective diagnostic HIV tropism system, yields predictive results and dissects virus mixtures. It is based on the duplexing of patient samples with selective DNA probes, combined with sequence-based analysis and replicative phenotyping for ambiguous samples. ...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000332003

    authors: Klimkait T

    更新日期:2012-01-01 00:00:00

  • Inhibition of cardiolipin synthesis following infection with herpes simplex virus.

    abstract::The results of this study show that the synthesis of the inner mitochondrial membrane phospholipid, cardiolipin, is markedly inhibited following infection of human embryonic lung or hamster embryo fibroblast cells with herpes simplex virus type 1 or 2. The synthesis of other phospholipids, i.e., phosphatidylcholine, p...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149969

    authors: Tucker T,Steiner MR,Steiner S

    更新日期:1974-01-01 00:00:00

  • Epidemiology of mammalian hepatitis E virus infection.

    abstract::Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000342301

    authors: Kaba M,Moal V,Gérolami R,Colson P

    更新日期:2013-01-01 00:00:00

  • Genomic heterogeneities in bovine herpesvirus type 1 viral isolates: a major variant selected from a field isolate.

    abstract::We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150192

    authors: Simard C,LaBoissière S,Séguin C,Trudel M

    更新日期:1991-01-01 00:00:00

  • Early alterations in the morphology of cytomegalovirus-infected human fibroblasts.

    abstract::Cytomegalovirus-infected human fibroblasts developed large numbers of fine microvilli within 90 min after addition of virus. The structure of these microvilli gradually changed as the infection proceeded, although the infected cells were easily detected by their large number of processes. These processes may be involv...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149058

    authors: Garnett HM

    更新日期:1979-01-01 00:00:00

  • Identification of the coat protein gene of bean golden mosaic geminivirus.

    abstract::An open-reading frame designated 1R1, on DNA component 1 of bean golden mosaic geminivirus (BGMV), has been identified as the coat protein gene. A DraI restriction fragment of BGMV DNA1 that includes 1R1 was inserted into the SmaI pKK223-3 expression vector. The 32 kD protein expressed in Escherichia coli cells reacte...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150208

    authors: Murayama A,Yamaya Y,Ikegami M

    更新日期:1991-01-01 00:00:00

  • Mycosis fungoides in European Russia: no antibodies to human T cell leukemia virus type I structural proteins, but virus-like sequences in blood and saliva.

    abstract:OBJECTIVE:Mycosis fungoides (MF) is the most frequent form of cutaneous T cell lymphoma (CTCL). Human T cell leukemia virus type 1 (HTLV-1) involvement in MF progression is a matter of debate. The goal of the investigation was to search for HTLV-1 markers in a group of MF patients from a nonendemic area to HTLV-1. MAT...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000086063

    authors: Morozov VA,Syrtsev AV,Ellerbrok H,Nikolaeva EV,Bavykin AS,Pauli G

    更新日期:2005-01-01 00:00:00

  • Loss of immunorecessive cytotoxic T lymphocyte determinant V on SV40 T antigen following cocultivation with site-specific cytotoxic T lymphocyte clone Y-5.

    abstract::Five distinct antigenic sites recognized by cytotoxic T lymphocytes in H-2b mice have been identified on simian virus 40 (SV40) T antigen. Cocultivation of SV40-transformed cells with cytotoxic T lymphocyte (CTL) clones specific for epitopes I-IV results in the selection of variants which show a loss of either epitope...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150154

    authors: Tanaka Y,Tevethia SS

    更新日期:1990-01-01 00:00:00

  • Natural antibodies to EBV-VCA antigens in common marmosets (Callithrix jacchus) and response after EBV inoculation.

    abstract::Healthy common marmosets from two separate colonies, one in England and one in France, were found to have antibodies cross-reacting with Epstein-Barr virus structural antigens (EBV-VCA). All seropositive animals were at least 2 years old. Experimental EBV infection of marmosets of different ages led to seroconversion ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149198

    authors: de-Thé G,Dubouch P,Fontaine C,Wedderburn N,Carter RL,Edwards MB,Cohen B

    更新日期:1980-01-01 00:00:00

  • Human T cell lymphotropic retroviruses: association with diseases of the nervous system.

    abstract::In less than 1% of persistently infected individuals, human T cell lymphotropic virus type I (HTLV-I) causes a chronic inflammatory disease of the central nervous system (CNS), called HTLV-I-associated myelopathy/tropical spastic paraparesis. Important prerequisites for disease induction are oligoclonal expansion of H...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150540

    authors: Kitze B,Brady JN

    更新日期:1997-01-01 00:00:00

  • Polyploidization of Epstein-Barr virus (EBV)-carrying lymphoma lines decreases the inducibility of EBV-determined early antigen following P3HR-1 virus superinfection or iododeoxyuridine treatment.

    abstract::Four tetraploid cell lines were derived from the Epstein-Barr virus (EBV)-carrying, nonproducer Burkitt lymphoma line Raji after colcemide treatment. EBV early antigen (EA) was induced by P3HR-1 virus superinfection and by iododeoxyuridine treatment. Inducibility was reduced in all tetraploid lines compared to the nea...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000148973

    authors: Shapiro IM,Andersson-Anvret M,Klein G

    更新日期:1978-01-01 00:00:00

  • Evidence that the amino acid composition of the particle proteins of plant viruses is characteristic of the virus group. II. Discriminant analysis according to structural biological and classification properties of plant viruses.

    abstract::The amino acid composition (AAC) of the coat proteins (CPs) of 126 plant viruses or strains were analyzed by stepwise discriminant analysis. The criteria chosen for discrimination were: the structure of virus particles (3 clusters); the mode of of transmission of the viruses (6 clusters); and the grouping of viruses a...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149675

    authors: Fauquet C,Dejardin J,Thouvenel JC

    更新日期:1986-01-01 00:00:00

  • Effects of poliovirus replication on undifferentiated and differentiated monocytic U937 cells: comparative studies with human macrophages.

    abstract::Poliovirus infection of either undifferentiated or differentiated U937 cells produced a decrease in the percentage of cells positive for the surface expression of the CD4, CD11c, CD14, or 8E11 antigens. The number of 4F2 surface molecules per cell increased in infected normal U937 cells, but was unaffected in differen...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150194

    authors: López-Guerrero JA,Cabañas C,Bernabeu C,Fresno M,Alonso MA

    更新日期:1991-01-01 00:00:00

  • Selected amino acid change encoding Epstein-Barr virus-specific T cell epitope of the LMP2A gene in Japanese nasal NK/T cell lymphoma patients.

    abstract::Nasal natural killer (NK)/T cell lymphoma is a peculiar lymphoma with a unique immunophenotype. Etiologically, in 1990, the authors first demonstrated the presence of Epstein-Barr virus (EBV) genomes and their products in this lymphoma. EBV-specific cytotoxic T lymphocytes (CTL) are very important in controlling the l...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000106462

    authors: Nagamine M,Kishibe K,Takahara M,Nagato T,Ishii H,Bandoh N,Ogino T,Harabuchi Y

    更新日期:2007-01-01 00:00:00

  • Dendritic cells and chronic hepatitis virus carriers.

    abstract::Many individuals infected with hepatitis B virus (HBV) and hepatitis C virus (HCV) are unable to clear these viruses following an acute infection and become chronically infected. There are more than 400 million HBV and HCV carriers in the world and a considerable number of these patients would eventually develop more ...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000050047

    authors: Akbar SM,Horiike N,Onji M,Hino O

    更新日期:2001-01-01 00:00:00

  • Role of the herpes simplex virus 1 internal repeat sequences in pathogenicity.

    abstract::Three independently isolated herpes simplex virus type 1 recombinant viruses containing a deletion of approximately 14 kilobase pairs, representing greater than 95% of the internal repeat DNA sequences, were analyzed for their pathogenicity in mice. The recombinant viruses were found to be avirulent, exhibiting drasti...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150147

    authors: Jenkins FJ,Martin JR

    更新日期:1990-01-01 00:00:00

  • Use of simian immunodeficiency viruses for AIDS research.

    abstract::Despite frequent statements to the contrary, there are good animal models for AIDS. In this review, we summarize the properties of one of the most useful animal models: infection of rhesus monkeys with simian immunodeficiency virus (SIV). The SIVs are an extensive group of HIV-related lentiviruses of nonhuman primates...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150108

    authors: Desrosiers RC,Ringler DJ

    更新日期:1989-01-01 00:00:00

  • Immunoelectrophoretic identification and purification of herpes simplex virus antigens released from infected cells in tissue culture.

    abstract::Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antige...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149020

    authors: Norrild B,Vestergaard BF

    更新日期:1979-01-01 00:00:00

  • Evolutionary relationship of three southern African maize streak virus isolates.

    abstract::The aligned restriction endonuclease maps of three sequenced maize streak virus isolates, three restriction-mapped southern African maize streak virus isolates, and two other sequenced geminiviruses were used as a means of calculating the sequence divergence between these viruses. The degree of divergence was used to ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150080

    authors: Kirby R,Clarke BA,Rybicki EP

    更新日期:1989-01-01 00:00:00

  • Effect of gamma-interferon or cycloheximide treatment on viral and c-myc transcripts in bovine-papillomavirus-type-1-transformed primary mouse fibroblasts.

    abstract::We have studied the effect of gamma-interferon (IFN-gamma) treatment on the transcription of viral and c-myc oncogenes in bovine papillomavirus type 1 (BPV-1)-transformed mouse fibroblast cell lines. Upon IFN-gamma treatment, viral transcripts always decreased in cell lines containing episomal BPV-1 DNA, while the eff...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150320

    authors: Agrawal R,Pelkonen J,Mäntyjärvi RA

    更新日期:1993-01-01 00:00:00

  • Origin and evolution of eukaryotic large nucleo-cytoplasmic DNA viruses.

    abstract:BACKGROUND/AIMS:The nucleo-cytoplasmic large DNA viruses (NCLDV) constitute an apparently monophyletic group that consists of 6 families of viruses infecting a broad variety of eukaryotes. A comprehensive genome comparison and maximum-likelihood reconstruction of NCLDV evolution reveal a set of approximately 50 conserv...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000312913

    authors: Koonin EV,Yutin N

    更新日期:2010-01-01 00:00:00

  • Characterization of potato yellow mosaic virus as a geminivirus with a bipartite genome.

    abstract::A whitefly-transmitted virus from Venezuela, potato yellow mosaic virus, has been propagated, isolated and characterized as a member of the Geminivirus group. The virus was transmitted to several species of Nicotiana and to Petunia hybrida by mechanical inoculation, and to potato and tomato plants by grafting. Purifie...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150042

    authors: Roberts EJ,Buck KW,Coutts RH

    更新日期:1988-01-01 00:00:00

  • Time-course of cowpea chlorotic mottle virus RNA replication.

    abstract::In a synchronous infection of cowpea chlorotic mottle virus in cowpea leaves, the three largest viral RNA components were synthesized throughout the infection at relatively constant ratios of two molecules of component 3 to one each of components 1 and 2. Component 4 (the coat protein message) was produced minimally d...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000148929

    authors: Dawson WO

    更新日期:1978-01-01 00:00:00

  • Experimental and spontaneous mucosal disease of cattle: a validation of Koch's postulates in the definition of pathogenesis.

    abstract::The complex etiology of mucosal disease of cattle has been unravelled by experimental reproduction of the fatal syndrome, thereby validating Koch's postulates. The causal virus, bovine virus diarrhea virus (BVDV), has two biotypes, noncytopathogenic and cytopathogenic; the former can infect the early bovine fetus, ind...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150295

    authors: Brownlie J,Clarke MC

    更新日期:1993-01-01 00:00:00

  • Low HBeAg serum levels correlate with the presence of the double A1762T/G1764A core promoter mutation and a positive response to interferon in patients with chronic hepatitis B virus infection.

    abstract:OBJECTIVE:To investigate the correlation of serum hepatitis B e antigen (HBeAg) levels with the presence of core promoter (CP) mutations, hepatitis B virus (HBV) viremia and the response to interferon (IFN) in patients with chronic hepatitis B. METHODS:Fourteen HBeAg-positive patients received alpha-2a IFN. Diluted se...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000072431

    authors: Marrone A,Zampino R,Luongo G,Utili R,Karayiannis P,Ruggiero G

    更新日期:2003-01-01 00:00:00

  • Effect of glucosamine on the replication of the arenavirus Junín in Vero cells.

    abstract::When Vero cells infected with Junín virus are cultured in the presence of 16 mM glucosamine, no infectious virus is produced and no surface antigens or virions are detected. Cytoplasmic viral antigen, however, is synthesized normally. ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149032

    authors: Martínez Peralta LA,León ME,Coto CE,Laguens RP

    更新日期:1979-01-01 00:00:00

  • HIV-2 in rhesus monkeys: serological, virological and clinical results.

    abstract::Diseases induced by animal retroviruses are not considered to be good models for the human acquired immunodeficiency syndrome (AIDS) at present. The lack of an animal model for the human immunodeficiency virus (HIV) infection presents a main problem in the complete understanding of the pathogenesis of HIV-mediated dis...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150125

    authors: Dormont D,Livartowski J,Chamaret S,Guetard D,Henin D,Levagueresse R,van de Moortelle PF,Larke B,Gourmelon P,Vazeux R

    更新日期:1989-01-01 00:00:00

  • Hepatitis C virus genotype in blood donors and associated liver disease in Indonesia.

    abstract:OBJECTIVE:The aim of this study was to investigate the distribution of hepatitis C virus (HCV) genotype and the possible association between genotype and HCV-associated liver disease in Indonesia. METHODS:32 anti-HCV-positive asymptomatic carriers (AC), 55 chronic hepatitis (CH), 41 liver cirrhosis (LC), and 35 hepato...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000205515

    authors: Utama A,Budiarto BR,Monasari D,Octavia TI,Chandra IS,Gani RA,Hasan I,Sanityoso A,Miskad UA,Yusuf I,Lesmana LA,Sulaiman A,Tai S

    更新日期:2008-01-01 00:00:00

  • Rotavirus genotypes in Costa Rica, Nicaragua, Honduras and the Dominican Republic.

    abstract::In this study, 574 stool samples from children with gastroenteritis were obtained from different hospitals in Costa Rica, Honduras, Nicaragua and the Dominican Republic during 2005-2006. Diarrhea stool samples were analyzed for rotavirus by ELISA and typed by the RT-PCR-based method. Unusual strains were detected: G1P...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000317288

    authors: Bourdett-Stanziola L,Ortega-Barria E,Espinoza F,Bucardo F,Jimenez C,Ferrera A

    更新日期:2010-01-01 00:00:00

  • Temperature-dependent phosphorylation state of the H5R protein synthesised at the early stage of infection in cells infected with vaccinia virus ts mutants of the B1R and F10L protein kinases.

    abstract::The phosphorylation state of H5R protein was investigated by two-dimensional gel electrophoresis of proteins of BSC-40 cells infected at 32 degrees or 39.5 degrees with vaccinia virus ts mutants of the viral B1R or F10L protein kinase genes. A temperature-dependent increase of underphosphorylated H5R protein (pI 6.8) ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000025025

    authors: Beaud G,Beaud R

    更新日期:2000-01-01 00:00:00