Abstract:
:Human skin fibroblasts were previously shown to be resistant to coxsackie B4 virus infection. We have cultured fibroblasts from skin and lung tissues of donors of various ages. By a novel method for direct assay of virus absorption and penetration, we have shown that skin fibroblasts from young fetuses are susceptible to coxsackie B4 infection, whereas those from older fetuses, children and adults are not and that this refractoriness is caused by a tissue-specific block to virus penetration.
journal_name
Intervirologyjournal_title
Intervirologyauthors
Hornberger E,Plotkin SAdoi
10.1159/000149360subject
Has Abstractpub_date
1983-01-01 00:00:00pages
195-200issue
4eissn
0300-5526issn
1423-0100journal_volume
19pub_type
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