Electron spin control of optically levitated nanodiamonds in vacuum.

abstract：:Nanoparticle-mediated delivery of functional macromolecules is a promising method for treating a variety of human diseases. Among nanoparticles, cell-derived exosomes have recently been highlighted as a new therapeutic strategy for the in vivo delivery of nucleotides and chemical drugs. Here we describe a new tool for...

journal_title：Nature communications

authors： Yim N,Ryu SW,Choi K,Lee KR,Lee S,Choi H,Kim J,Shaker MR,Sun W,Park JH,Kim D,Heo WD,Choi C

更新日期：2016-07-22 00:00:00

abstract：:An incorrect version of the Supplementary Information was inadvertently published with this Article. The HTML has now been updated to include the correct version of the Supplementary Information. ...

journal_title：Nature communications

authors： Palmer EM,Heggy E,Kofman W

更新日期：2017-11-23 00:00:00

abstract：:Inflammation is recognized as one of the drivers of cancer. Yet, the individual immune components that possess pro- and anti-tumorigenic functions in individual cancers remain largely unknown. NKG2D is a potent activating immunoreceptor that has emerged as an important player in inflammatory disorders besides its well...

journal_title：Nature communications

authors： Sheppard S,Guedes J,Mroz A,Zavitsanou AM,Kudo H,Rothery SM,Angelopoulos P,Goldin R,Guerra N

更新日期：2017-01-27 00:00:00

abstract：:To balance immunity and tolerance, the endogenous pool of Foxp3+ regulatory T (Treg) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of Treg cells is negatively regulated by the kinase Lkb1 in dendritic cells (DCs). Conditional knockout ...

journal_title：Nature communications

authors： Chen S,Fang L,Guo W,Zhou Y,Yu G,Li W,Dong K,Liu J,Luo Y,Wang B,Li Z,Zhao C,Sun Z,Shen Y,Leng Q,Zhou D,Han Z,Huang H,Ren H,Xu G,Feng X

更新日期：2018-12-13 00:00:00

abstract：:The development of transistors with high gain is essential for applications ranging from switching elements and drivers to transducers for chemical and biological sensing. Organic transistors have become well-established based on their distinct advantages, including ease of fabrication, synthetic freedom for chemical ...

journal_title：Nature communications

authors： Khodagholy D,Rivnay J,Sessolo M,Gurfinkel M,Leleux P,Jimison LH,Stavrinidou E,Herve T,Sanaur S,Owens RM,Malliaras GG

更新日期：2013-01-01 00:00:00

abstract：:Sclerosing stromal tumor (SST) of the ovary is a rare type of sex cord-stromal tumor (SCST), whose genetic underpinning is currently unknown. Here, using whole-exome, targeted capture and RNA-sequencing, we report recurrent FHL2-GLI2 fusion genes in 65% (17/26) of SSTs and other GLI2 rearrangements in additional 15% (...

journal_title：Nature communications

authors： Kim SH,Da Cruz Paula A,Basili T,Dopeso H,Bi R,Pareja F,da Silva EM,Gularte-Mérida R,Sun Z,Fujisawa S,Smith CG,Ferrando L,Martins Sebastião AP,Bykov Y,Li A,Silveira C,Ashley CW,Stylianou A,Selenica P,Samore WR,Jung

更新日期：2020-01-02 00:00:00

abstract：:Mutant Huntingtin (mtHtt) causes neurodegeneration in Huntington's disease (HD) by evoking defects in the mitochondria, but the underlying mechanisms remains elusive. Our proteomic analysis identifies valosin-containing protein (VCP) as an mtHtt-binding protein on the mitochondria. Here we show that VCP is selectively...

journal_title：Nature communications

authors： Guo X,Sun X,Hu D,Wang YJ,Fujioka H,Vyas R,Chakrapani S,Joshi AU,Luo Y,Mochly-Rosen D,Qi X

更新日期：2016-08-26 00:00:00

abstract：:High-harmonic generation (HHG) in gases has been the main enabling technology of attosecond science since its discovery. Recently, HHG from solids has been demonstrated, opening a lively area of research. In contrast, harmonic generation from liquids has so far remained restricted to low harmonics in the visible regim...

journal_title：Nature communications

authors： Luu TT,Yin Z,Jain A,Gaumnitz T,Pertot Y,Ma J,Wörner HJ

更新日期：2018-09-13 00:00:00

abstract：:Pattern-triggered immunity and effector-triggered immunity are two primary forms of innate immunity in land plants. The molecular components and connecting nodes of pattern-triggered immunity and effector-triggered immunity are not fully understood. Here, we report that the Arabidopsis calcium-dependent protein kinase...

journal_title：Nature communications

authors： Lu YJ,Li P,Shimono M,Corrion A,Higaki T,He SY,Day B

更新日期：2020-12-04 00:00:00

abstract：:Janus, patchy, stripe-like, or random arrangements of molecules within the ligand shell of nanoparticles affect many properties. Among all existing ligand shell morphology characterization methods, the one based on mass spectroscopy is arguably the simplest. Its greatest limitation is that the results are qualitative....

journal_title：Nature communications

authors： Luo Z,Zhao Y,Darwish T,Wang Y,Hou J,Stellacci F

更新日期：2018-10-26 00:00:00

abstract：:Transcription of eukaryotic protein-coding genes requires passage of RNA polymerase II (Pol II) through nucleosomes, but it is unclear how this is achieved. Here we report the cryo-EM structure of transcribing Saccharomyces cerevisiae Pol II engaged with a downstream nucleosome core particle at an overall resolution o...

journal_title：Nature communications

authors： Farnung L,Vos SM,Cramer P

更新日期：2018-12-21 00:00:00

abstract：:A superconducting state is characterized by the gap in the electronic density of states, which vanishes at the superconducting transition temperature T(c). It was discovered that in high-temperature superconductors, a noticeable depression in the density of states, the pseudogap, still remains even at temperatures abo...

journal_title：Nature communications

authors： Sacépé B,Chapelier C,Baturina TI,Vinokur VM,Baklanov MR,Sanquer M

更新日期：2010-01-01 00:00:00

abstract：:The growing realization of a looming biodiversity crisis has inspired considerable progress in the quest to link biodiversity, structure and ecosystem function. Here we construct a method that bridges low- and high-diversity approaches to food web theory by elucidating the connection between the stability of the basic...

journal_title：Nature communications

authors： Gellner G,McCann KS

更新日期：2016-04-12 00:00:00

abstract：:Nonequilibrium atomic structures can host exotic and technologically relevant properties in otherwise conventional materials. Oxygen octahedral rotation forms a fundamental atomic distortion in perovskite oxides, but only a few patterns are predominantly present at equilibrium. This has restricted the range of possibl...

journal_title：Nature communications

authors： Kim JR,Jang J,Go KJ,Park SY,Roh CJ,Bonini J,Kim J,Lee HG,Rabe KM,Lee JS,Choi SY,Noh TW,Lee D

更新日期：2020-10-02 00:00:00

abstract：:Atropisomers are important organic frameworks in bioactive natural products, drugs as well as chiral catalysts. Meanwhile, silanols display unique properties compared to their alcohol analogs, however, the catalytic synthesis of atropisomers bearing silanol groups is challenging. Here, we show a rhodium-catalyzed tors...

journal_title：Nature communications

authors： Feng J,Bi X,Xue X,Li N,Shi L,Gu Z

更新日期：2020-09-07 00:00:00

abstract：:Modern ab initio calculations predict ionic and superionic states in highly compressed water and ammonia. The prediction apparently contradicts state-of-the-art experimentally established phase diagrams overwhelmingly dominated by molecular phases. Here we present experimental evidence that the threshold pressure of ~...

journal_title：Nature communications

authors： Palasyuk T,Troyan I,Eremets M,Drozd V,Medvedev S,Zaleski-Ejgierd P,Magos-Palasyuk E,Wang H,Bonev SA,Dudenko D,Naumov P

更新日期：2014-03-24 00:00:00

abstract：:Accurately predicting chromatin loops from genome-wide interaction matrices such as Hi-C data is critical to deepening our understanding of proper gene regulation. Current approaches are mainly focused on searching for statistically enriched dots on a genome-wide map. However, given the availability of orthogonal data...

journal_title：Nature communications

authors： Salameh TJ,Wang X,Song F,Zhang B,Wright SM,Khunsriraksakul C,Ruan Y,Yue F

更新日期：2020-07-09 00:00:00

abstract：:Scleroderma is an autoimmune rheumatic disorder accompanied by severe fibrosis in skin and other internal organs. During scleroderma progression, resident fibroblasts undergo activation and convert to α-smooth muscle actin (α-SMA) expressing myofibroblasts (MFBs) with increased capacity to synthesize collagens and fib...

journal_title：Nature communications

authors： Park JS,Oh Y,Park YJ,Park O,Yang H,Slania S,Hummers LK,Shah AA,An HT,Jang J,Horton MR,Shin J,Dietz HC,Song E,Na DH,Park EJ,Kim K,Lee KC,Roschke VV,Hanes J,Pomper MG,Lee S

更新日期：2019-03-08 00:00:00

abstract：:The effective delivery of therapeutics to disease sites significantly contributes to drug efficacy, toxicity and clearance. Here we demonstrate that clinically approved iron oxide nanoparticles (Ferumoxytol) can be utilized to carry one or multiple drugs. These so called 'nanophores' retain their cargo within their po...

journal_title：Nature communications

authors： Kaittanis C,Shaffer TM,Ogirala A,Santra S,Perez JM,Chiosis G,Li Y,Josephson L,Grimm J

更新日期：2014-03-04 00:00:00

abstract：:Accumulating evidence suggests that transcriptional regulation is required for maintenance of long-term memories (LTMs). Here we characterize global transcriptional and epigenetic changes that occur during LTM storage in the Drosophila mushroom bodies (MBs), structures important for memory. Although LTM formation requ...

journal_title：Nature communications

authors： Hirano Y,Ihara K,Masuda T,Yamamoto T,Iwata I,Takahashi A,Awata H,Nakamura N,Takakura M,Suzuki Y,Horiuchi J,Okuno H,Saitoe M

更新日期：2016-11-14 00:00:00

abstract：:Nascent polypeptides can induce ribosome stalling, regulating downstream genes. Stalling of ErmBL peptide translation in the presence of the macrolide antibiotic erythromycin leads to resistance in Streptococcus sanguis. To reveal this stalling mechanism we obtained 3.6-Å-resolution cryo-EM structures of ErmBL-stalled...

journal_title：Nature communications

authors： Arenz S,Bock LV,Graf M,Innis CA,Beckmann R,Grubmüller H,Vaiana AC,Wilson DN

更新日期：2016-07-06 00:00:00

abstract：:Closed timelike curves are striking predictions of general relativity allowing for time-travel. They are afflicted by notorious causality issues (e.g. grandfather's paradox). Quantum models where a qubit travels back in time solve these problems, at the cost of violating quantum theory's linearity-leading e.g. to univ...

journal_title：Nature communications

authors： Marletto C,Vedral V,Virzì S,Rebufello E,Avella A,Piacentini F,Gramegna M,Degiovanni IP,Genovese M

更新日期：2019-01-14 00:00:00

abstract：:Ever since its discovery around a decade ago, all-optical magnetization switching (AOS) using femtosecond laser pulses has shown potential for future data storage and logic devices. In particular, single pulse helicity independent AOS in certain ferrimagnetic alloys and multilayers is highly efficient and ultrafast. H...

journal_title：Nature communications

authors： van Hees YLW,van de Meugheuvel P,Koopmans B,Lavrijsen R

更新日期：2020-07-31 00:00:00

abstract：:Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-cells. Prognosis is strongly associated with molecular subgroup, although the driver mutations that distinguish the two main subgroups remain poorly defined. Through an integrative analysis of whole genomes, exomes, and transcripto...

journal_title：Nature communications

authors： Arthur SE,Jiang A,Grande BM,Alcaide M,Cojocaru R,Rushton CK,Mottok A,Hilton LK,Lat PK,Zhao EY,Culibrk L,Ennishi D,Jessa S,Chong L,Thomas N,Pararajalingam P,Meissner B,Boyle M,Davidson J,Bushell KR,Lai D,Farinha

更新日期：2018-10-01 00:00:00

abstract：:The ventral striatum has long been proposed as an integrator of biologically significant associative information to drive actions. Although inputs from the amygdala and hippocampus have been much studied, the role of prominent inputs from orbitofrontal cortex (OFC) are less well understood. Here, we recorded single-un...

journal_title：Nature communications

authors： Cooch NK,Stalnaker TA,Wied HM,Bali-Chaudhary S,McDannald MA,Liu TL,Schoenbaum G

更新日期：2015-05-21 00:00:00

abstract：:Roughly a third (~30 ppm) of the carbon dioxide (CO2) that entered the ocean during ice ages is attributed to biological mechanisms. A leading hypothesis for the biological drawdown of CO2 is iron (Fe) fertilisation of the high latitudes, but modelling efforts attribute at most 10 ppm to this mechanism, leaving ~20 pp...

journal_title：Nature communications

authors： Buchanan PJ,Chase Z,Matear RJ,Phipps SJ,Bindoff NL

更新日期：2019-10-10 00:00:00

abstract：:The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Through machine learning and multi-omics factor analysis, we compare and contrast the genomic profiles of 116 pulmonary carcinoids (including 35 atypical), 75 large-cell neuroendocrine carcinomas (...

journal_title：Nature communications

authors： Alcala N,Leblay N,Gabriel AAG,Mangiante L,Hervas D,Giffon T,Sertier AS,Ferrari A,Derks J,Ghantous A,Delhomme TM,Chabrier A,Cuenin C,Abedi-Ardekani B,Boland A,Olaso R,Meyer V,Altmuller J,Le Calvez-Kelm F,Durand G,V

更新日期：2019-08-20 00:00:00

abstract：:Although optical technology provides the best solution for the transmission of information, all-optical devices must satisfy several qualitative criteria to be used as logic elements. In particular, cascadability is difficult to obtain in optical systems, and it is assured only if the output of one stage is in the cor...

journal_title：Nature communications

authors： Ballarini D,De Giorgi M,Cancellieri E,Houdré R,Giacobino E,Cingolani R,Bramati A,Gigli G,Sanvitto D

更新日期：2013-01-01 00:00:00

abstract：:The capability to detect traces of explosives sensitively, selectively and rapidly could be of great benefit for applications relating to civilian national security and military needs. Here, we show that, when chemically modified in a multiplexed mode, nanoelectrical devices arrays enable the supersensitive discrimina...

journal_title：Nature communications

authors： Lichtenstein A,Havivi E,Shacham R,Hahamy E,Leibovich R,Pevzner A,Krivitsky V,Davivi G,Presman I,Elnathan R,Engel Y,Flaxer E,Patolsky F

更新日期：2014-06-24 00:00:00

abstract：:Ferromagnetism is usually deemed incompatible with superconductivity. Consequently, the coexistence of superconductivity and ferromagnetism is usually observed only in elegantly designed multi-ingredient structures in which the two competing electronic states originate from separate structural components. Here we repo...

journal_title：Nature communications

authors： Zhu X,Guo Y,Cheng H,Dai J,An X,Zhao J,Tian K,Wei S,Cheng Zeng X,Wu C,Xie Y

更新日期：2016-04-04 00:00:00