Arabidopsis calcium-dependent protein kinase 3 regulates actin cytoskeleton organization and immunity.

abstract：:The shift from maternal to embryonic control is a critical developmental milestone in preimplantation development. Widespread transcriptomic and epigenetic remodeling facilitate this transition from terminally differentiated gametes to totipotent blastomeres, but the identity of transcription factors (TF) and genomic ...

journal_title：Nature communications

authors： Halstead MM,Ma X,Zhou C,Schultz RM,Ross PJ

更新日期：2020-09-17 00:00:00

abstract：:Herein, we report on a significant discovery, namely, the quantitative discharging of reduced graphite forms, such as graphite intercalation compounds, graphenide dispersions and graphenides deposited on surfaces with the simple solvent benzonitrile. Because of its comparatively low reduction potential, benzonitrile i...

journal_title：Nature communications

authors： Vecera P,Holzwarth J,Edelthalhammer KF,Mundloch U,Peterlik H,Hauke F,Hirsch A

更新日期：2016-08-10 00:00:00

abstract：:Loss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to chronic inflammation and increased morbidity and mortality during antiretroviral-treated HIV disease. Sexual practice has recently been uncovered as a major source of microbiota variation, potentially confounding prior...

journal_title：Nature communications

authors： Vujkovic-Cvijin I,Sortino O,Verheij E,Sklar J,Wit FW,Kootstra NA,Sellers B,Brenchley JM,Ananworanich J,Loeff MSV,Belkaid Y,Reiss P,Sereti I

更新日期：2020-05-15 00:00:00

abstract：:Oxide-ion conductors have found applications in various electrochemical devices, such as solid-oxide fuel cells, gas sensors, and separation membranes. Dion-Jacobson phases are known for their rich magnetic and electrical properties; however, there have been no reports on oxide-ion conduction in this family of materia...

journal_title：Nature communications

authors： Zhang W,Fujii K,Niwa E,Hagihala M,Kamiyama T,Yashima M

更新日期：2020-03-06 00:00:00

abstract：:Metastasis is the main cause of cancer-related death and thus understanding the molecular and cellular mechanisms underlying this process is critical. Here, our data demonstrate, contrary to established dogma, that loss of haematopoietic-derived focal adhesion kinase (FAK) is sufficient to enhance tumour metastasis. U...

journal_title：Nature communications

authors： Batista S,Maniati E,Reynolds LE,Tavora B,Lees DM,Fernandez I,Elia G,Casanovas O,Lo Celso C,Hagemann T,Hodivala-Dilke K

更新日期：2014-10-01 00:00:00

abstract：:Transition metal reagents and catalysts are generally effective to cleave all three bonds (one σ and two π) in a triple bond despite its high bonding energy. Recently, chemistry of single-bond cleavage by using main-group element compounds is rapidly being developed in the absence of transition metals. However, the cl...

journal_title：Nature communications

authors： Asakawa H,Lee KH,Lin Z,Yamashita M

更新日期：2014-06-26 00:00:00

abstract：:Human-machine interfaces have benefited from the advent of wireless sensor networks and the internet of things, but rely on wearable/attachable electronics exhibiting stretchability, biocompatibility, and transmittance. Limited by weight and volume, wearable devices should be energy efficient and even self-powered. He...

journal_title：Nature communications

authors： Lee Y,Cha SH,Kim YW,Choi D,Sun JY

更新日期：2018-05-04 00:00:00

abstract：:Human metapneumovirus (hMPV) is a frequent cause of bronchiolitis in young children. Its F glycoprotein mediates virus-cell membrane fusion and is the primary target of neutralizing antibodies. The inability to produce recombinant hMPV F glycoprotein in the metastable pre-fusion conformation has hindered structural an...

journal_title：Nature communications

authors： Battles MB,Más V,Olmedillas E,Cano O,Vázquez M,Rodríguez L,Melero JA,McLellan JS

更新日期：2017-11-16 00:00:00

abstract：:A recent review concluded that earthworm presence increases CO₂ emissions by 33% but does not affect soil organic carbon stocks. However, the findings are controversial and raise new questions. Here we hypothesize that neither an increase in CO₂ emission nor in stabilized carbon would entirely reflect the earthworms' ...

journal_title：Nature communications

authors： Zhang W,Hendrix PF,Dame LE,Burke RA,Wu J,Neher DA,Li J,Shao Y,Fu S

更新日期：2013-01-01 00:00:00

abstract：:The indisputable role of epigenetics in cancer and the fact that epigenetic alterations can be reversed have favoured development of epigenetic drugs. In this study, we design and synthesize potent novel, selective and reversible chemical probes that simultaneously inhibit the G9a and DNMTs methyltransferase activity....

journal_title：Nature communications

authors： San José-Enériz E,Agirre X,Rabal O,Vilas-Zornoza A,Sanchez-Arias JA,Miranda E,Ugarte A,Roa S,Paiva B,Estella-Hermoso de Mendoza A,Alvarez RM,Casares N,Segura V,Martín-Subero JI,Ogi FX,Soule P,Santiveri CM,Campos-Olivas

更新日期：2017-05-26 00:00:00

abstract：:Human pre-implantation embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here, we report on LiCAT-seq, a technique that enables simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells, and map the chromatin accessibility an...

journal_title：Nature communications

authors： Liu L,Leng L,Liu C,Lu C,Yuan Y,Wu L,Gong F,Zhang S,Wei X,Wang M,Zhao L,Hu L,Wang J,Yang H,Zhu S,Chen F,Lu G,Shang Z,Lin G

更新日期：2019-01-21 00:00:00

abstract：:Topological insulators represent a new quantum state of matter that are insulating in the bulk but metallic on the edge or surface. In the Dirac surface state, it is well-established that the electron spin is locked with the crystal momentum. Here we report a new phenomenon of the spin texture locking with the orbital...

journal_title：Nature communications

authors： Xie Z,He S,Chen C,Feng Y,Yi H,Liang A,Zhao L,Mou D,He J,Peng Y,Liu X,Liu Y,Liu G,Dong X,Yu L,Zhang J,Zhang S,Wang Z,Zhang F,Yang F,Peng Q,Wang X,Chen C,Xu Z,Zhou XJ

更新日期：2014-02-28 00:00:00

abstract：:A transcriptional programme initiated by the proneural factors Neurog2 and Ascl1 controls successive steps of neurogenesis in the embryonic cerebral cortex. Previous work has shown that proneural factors also confer a migratory behaviour to cortical neurons by inducing the expression of the small GTP-binding proteins ...

journal_title：Nature communications

authors： Azzarelli R,Pacary E,Garg R,Garcez P,van den Berg D,Riou P,Ridley AJ,Friedel RH,Parsons M,Guillemot F

更新日期：2014-02-27 00:00:00

abstract：:Iron sequestration by host proteins contributes to the defence against bacterial pathogens, which need iron for their metabolism and virulence. A Pseudomonas aeruginosa mutant lacking all three known iron acquisition systems retains the ability to grow in media containing iron chelators, suggesting the presence of add...

journal_title：Nature communications

authors： Lin J,Zhang W,Cheng J,Yang X,Zhu K,Wang Y,Wei G,Qian PY,Luo ZQ,Shen X

更新日期：2017-03-28 00:00:00

abstract：:Understanding climate change-associated tree mortality is central to linking climate change impacts and forest structure and function. However, whether temporal increases in tree mortality are attributed to climate change or stand developmental processes remains uncertain. Furthermore, interpreting the climate change-...

journal_title：Nature communications

authors： Luo Y,Chen HY

更新日期：2013-01-01 00:00:00

abstract：:Emerging data suggest that locoregional cancer therapeutic approaches with oncolytic viruses can lead to systemic anti-tumour immunity, although the appropriate targets for intratumoral immunomodulation using this strategy are not known. Here we find that intratumoral therapy with Newcastle disease virus (NDV), in add...

journal_title：Nature communications

authors： Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP

更新日期：2017-02-13 00:00:00

abstract：:In the human hematopoietic system, rare self-renewing multipotent long-term hematopoietic stem cells (LT-HSCs) are responsible for the lifelong production of mature blood cells and are the rational target for clinical regenerative therapies. However, the heterogeneity in the hematopoietic stem cell compartment and var...

journal_title：Nature communications

authors： Wagenblast E,Azkanaz M,Smith SA,Shakib L,McLeod JL,Krivdova G,Araújo J,Shultz LD,Gan OI,Dick JE,Lechman ER

更新日期：2019-10-18 00:00:00

abstract：:Amyloid supramolecular assemblies have found widespread exploitation as ordered nanomaterials in a range of applications from materials science to biotechnology. New strategies are, however, required for understanding and promoting mature fibril formation from simple monomer motifs through easy and scalable processes....

journal_title：Nature communications

authors： Bertolani A,Pirrie L,Stefan L,Houbenov N,Haataja JS,Catalano L,Terraneo G,Giancane G,Valli L,Milani R,Ikkala O,Resnati G,Metrangolo P

更新日期：2015-06-30 00:00:00

abstract：:Loss of protein and organelle quality control secondary to reduced autophagy is a hallmark of aging. However, the physiologic and molecular regulation of autophagy in long-lived organisms remains incompletely understood. Here we show that the Kruppel-like family of transcription factors are important regulators of aut...

journal_title：Nature communications

authors： Hsieh PN,Zhou G,Yuan Y,Zhang R,Prosdocimo DA,Sangwung P,Borton AH,Boriushkin E,Hamik A,Fujioka H,Fealy CE,Kirwan JP,Peters M,Lu Y,Liao X,Ramírez-Bergeron D,Feng Z,Jain MK

更新日期：2017-10-13 00:00:00

abstract：:G protein-coupled receptors (GPCRs) constitute a large family of receptors that activate intracellular signaling pathways upon detecting specific extracellular ligands. While many aspects of GPCR signaling have been uncovered through decades of studies, some fundamental properties, like its channel capacity-a measure ...

journal_title：Nature communications

authors： Keshelava A,Solis GP,Hersch M,Koval A,Kryuchkov M,Bergmann S,Katanaev VL

更新日期：2018-02-28 00:00:00

abstract：:Long-range chromatin interactions are important for transcriptional regulation of genes, many of which are related to complex agronomics traits. However, the pattern of three-dimensional chromatin interactions remains unclear in plants. Here we report the generation of chromatin interaction analysis by paired-end tag ...

journal_title：Nature communications

authors： Li E,Liu H,Huang L,Zhang X,Dong X,Song W,Zhao H,Lai J

更新日期：2019-06-14 00:00:00

abstract：:Water resources are being challenged to meet domestic, agricultural, and industrial needs. To complement finite surface water supplies that are being stressed by changes in precipitation and increased demand, groundwater is increasingly being used. Sustaining groundwater use requires considering both water quantity an...

journal_title：Nature communications

authors： Smith R,Knight R,Fendorf S

更新日期：2018-06-05 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Weinert LA,Chaudhuri RR,Wang J,Peters SE,Corander J,Jombart T,Baig A,Howell KJ,Vehkala M,Välimäki N,Harris D,Chieu TTB,Van Vinh Chau N,Campbell J,Schultsz C,Parkhill J,Bentley SD,Langford PR,Rycroft AN,Wren BW,Far

更新日期：2019-11-22 00:00:00

abstract：:Some bacteria can feed on fungi, a phenomenon known as mycophagy. Here we show that a prophage tail-like protein (Bg_9562) is essential for mycophagy in Burkholderia gladioli strain NGJ1. The purified protein causes hyphal disintegration and inhibits growth of several fungal species. Disruption of the Bg_9562 gene abo...

journal_title：Nature communications

authors： Swain DM,Yadav SK,Tyagi I,Kumar R,Kumar R,Ghosh S,Das J,Jha G

更新日期：2017-09-01 00:00:00

abstract：:The interpretation of molecular vibrational spectroscopic signals in terms of atomic motion is essential to understand molecular mechanisms and for chemical characterization. The signals are usually assigned after harmonic normal mode analysis, even if molecular vibrations are known to be anharmonic. Here we obtain th...

journal_title：Nature communications

authors： Aieta C,Micciarelli M,Bertaina G,Ceotto M

更新日期：2020-08-28 00:00:00

abstract：:Van der Waals materials and heterostructures that manifest strongly bound exciton states at room temperature also exhibit emergent physical phenomena and are of great promise for optoelectronic applications. Here, we demonstrate that nanostructured, multilayer transition metal dichalcogenides (TMDCs) by themselves pro...

journal_title：Nature communications

authors： Zhang H,Abhiraman B,Zhang Q,Miao J,Jo K,Roccasecca S,Knight MW,Davoyan AR,Jariwala D

更新日期：2020-07-15 00:00:00

abstract：:Structural rearrangements govern the various properties of disordered systems and visualization of these dynamical processes can provide critical information on structural deformation and phase transformation of the systems. However, direct imaging of individual atoms or molecules in a disordered state is quite challe...

journal_title：Nature communications

authors： Choe J,Lee Y,Park J,Kim Y,Kim CU,Kim K

更新日期：2019-09-27 00:00:00

abstract：:Disease epidemiology during ageing shows a transition from cancer to degenerative chronic disorders as dominant contributors to mortality in the old. Nevertheless, it has remained unclear to what extent molecular signatures of ageing reflect this phenomenon. Here we report on the identification of a conserved transcri...

journal_title：Nature communications

authors： Aramillo Irizar P,Schäuble S,Esser D,Groth M,Frahm C,Priebe S,Baumgart M,Hartmann N,Marthandan S,Menzel U,Müller J,Schmidt S,Ast V,Caliebe A,König R,Krawczak M,Ristow M,Schuster S,Cellerino A,Diekmann S,Englert C

更新日期：2018-01-30 00:00:00

abstract：:Room-temperature infrared sub-band gap photoresponse in silicon is of interest for telecommunications, imaging and solid-state energy conversion. Attempts to induce infrared response in silicon largely centred on combining the modification of its electronic structure via controlled defect formation (for example, vacan...

journal_title：Nature communications

authors： Mailoa JP,Akey AJ,Simmons CB,Hutchinson D,Mathews J,Sullivan JT,Recht D,Winkler MT,Williams JS,Warrender JM,Persans PD,Aziz MJ,Buonassisi T

更新日期：2014-01-01 00:00:00

abstract：:SMC (structural maintenance of chromosomes) family members play essential roles in chromosome condensation, sister chromatid cohesion and DNA repair. It remains unclear how SMCs structure chromosomes and how their mechanochemical cycle regulates their interactions with DNA. Here we used single-molecule fluorescence mi...

journal_title：Nature communications

authors： Kim H,Loparo JJ

更新日期：2016-01-04 00:00:00