Catalytic asymmetric C-Si bond activation via torsional strain-promoted Rh-catalyzed aryl-Narasaka acylation.

abstract：:Mineralisation of calcium phosphates in bone has been proposed to proceed via an initial amorphous precursor phase which transforms into nanocrystalline, carbonated hydroxyapatite. While calcium phosphates have been under intense investigation, the exact steps during the crystallisation of spherical amorphous particle...

journal_title：Nature communications

authors： Lotsari A,Rajasekharan AK,Halvarsson M,Andersson M

更新日期：2018-10-09 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with features that vary by ethnicity. A systematic characterization of the genomic landscape of Chinese ccRCC is lacking, and features of ccRCC associated with tumor thrombus (ccRCC-TT) remain poorly understood. Here, we applied whole-exome sequencing ...

journal_title：Nature communications

authors： Wang XM,Lu Y,Song YM,Dong J,Li RY,Wang GL,Wang X,Zhang SD,Dong ZH,Lu M,Wang SY,Ge LY,Luo GD,Ma RZ,George Rozen S,Bai F,Wu D,Ma LL

更新日期：2020-02-06 00:00:00

abstract：:In 2016 the World Health Organization identified 21 countries that could eliminate malaria by 2020. Monitoring progress towards this goal requires tracking ongoing transmission. Here we develop methods that estimate individual reproduction numbers and their variation through time and space. Individual reproduction num...

journal_title：Nature communications

authors： Routledge I,Chevéz JER,Cucunubá ZM,Rodriguez MG,Guinovart C,Gustafson KB,Schneider K,Walker PGT,Ghani AC,Bhatt S

更新日期：2018-06-26 00:00:00

abstract：:Field-effect transistors based on carbon nanotubes have been shown to be faster and less energy consuming than their silicon counterparts. However, ensuring these advantages are maintained for integrated circuits is a challenge. Here we demonstrate that a significant reduction in the use of field-effect transistors ca...

journal_title：Nature communications

authors： Ding L,Zhang Z,Liang S,Pei T,Wang S,Li Y,Zhou W,Liu J,Peng LM

更新日期：2012-02-14 00:00:00

abstract：:Within all physical disciplines, it is accepted that wave transport is predetermined by the existence of disorder. In this vein, it is known that ballistic transport is possible only when a structure is ordered, and that disorder is crucial for diffusion or (Anderson-)localization to occur. As this commonly accepted p...

journal_title：Nature communications

authors： Eichelkraut T,Heilmann R,Weimann S,Stützer S,Dreisow F,Christodoulides DN,Nolte S,Szameit A

更新日期：2013-01-01 00:00:00

abstract：:Lysosomes are the major degradative compartments within cells, harbouring a wide variety of hydrolytic enzymes within their lumen. Release of lysosomal hydrolases from lysosomes into the cell cytoplasm results in cell death. Here we report that damaged lysosomes undergo autophagic turnover. Using a light-induced lysos...

journal_title：Nature communications

authors： Hung YH,Chen LM,Yang JY,Yang WY

更新日期：2013-01-01 00:00:00

abstract：:The combined effects of anthropogenic and biological CO2 inputs may lead to more rapid acidification in coastal waters compared to the open ocean. It is less clear, however, how redox reactions would contribute to acidification. Here we report estuarine acidification dynamics based on oxygen, hydrogen sulfide (H2S), p...

journal_title：Nature communications

authors： Cai WJ,Huang WJ,Luther GW 3rd,Pierrot D,Li M,Testa J,Xue M,Joesoef A,Mann R,Brodeur J,Xu YY,Chen B,Hussain N,Waldbusser GG,Cornwell J,Kemp WM

更新日期：2017-08-28 00:00:00

abstract：:The original HTML version of this Article had an incorrect Published online date of 20 March 2019; it should have been 18 March 2019. This has been corrected in the HTML version of the Article. The PDF version was correct from the time of publication. ...

journal_title：Nature communications

authors： Hu Z,Wessels HJCT,van Alen T,Jetten MSM,Kartal B

更新日期：2019-04-18 00:00:00

abstract：:Regulatory T (Treg) cells derived from the thymus (tTreg) and periphery (pTreg) have central and distinct functions in immunosuppression, but mechanisms for the generation and activation of Treg subsets in vivo are unclear. Here, we show that mechanistic target of rapamycin (mTOR) unexpectedly supports the homeostasis...

journal_title：Nature communications

authors： Chapman NM,Zeng H,Nguyen TM,Wang Y,Vogel P,Dhungana Y,Liu X,Neale G,Locasale JW,Chi H

更新日期：2018-05-29 00:00:00

abstract：:Chloroplasts communicate information by signalling to nuclei during acclimation to fluctuating light. Several potential operating signals originating from chloroplasts have been proposed, but none have been shown to move to nuclei to modulate gene expression. One proposed signal is hydrogen peroxide (H2O2) produced by...

journal_title：Nature communications

authors： Exposito-Rodriguez M,Laissue PP,Yvon-Durocher G,Smirnoff N,Mullineaux PM

更新日期：2017-06-29 00:00:00

abstract：:The high photon flux and femtosecond pulse duration of hard X-ray free-electron lasers have spurred a large variety of novel and fascinating experiments in physical, chemical and biological sciences. Many of these experiments depend fundamentally on a clean, well-defined wavefront. Here we explore the wavefront proper...

journal_title：Nature communications

authors： Rutishauser S,Samoylova L,Krzywinski J,Bunk O,Grünert J,Sinn H,Cammarata M,Fritz DM,David C

更新日期：2012-07-10 00:00:00

abstract：:Microbial fatty acid-derived fuels have emerged as promising alternatives to petroleum-based transportation fuels. Here we report a modular engineering approach that systematically removed metabolic pathway bottlenecks and led to significant titre improvements in a multi-gene fatty acid metabolic pathway. On the basis...

journal_title：Nature communications

authors： Xu P,Gu Q,Wang W,Wong L,Bower AG,Collins CH,Koffas MA

更新日期：2013-01-01 00:00:00

abstract：:Interactions between metal nanoparticles and support materials can strongly influence the performance of catalysts. In particular, reducible oxidic supports can form suboxides that can decorate metal nanoparticles and enhance catalytic performance or block active sites. Therefore, tuning this metal-support interaction...

journal_title：Nature communications

authors： Hernández Mejía C,van Deelen TW,de Jong KP

更新日期：2018-10-26 00:00:00

abstract：:Cyanobacteria are model organisms for photosynthesis and are attractive for biotechnology applications. To aid investigation of genotype-phenotype relationships in cyanobacteria, we develop an inducible CRISPRi gene repression library in Synechocystis sp. PCC 6803, where we aim to target all genes for repression. We t...

journal_title：Nature communications

authors： Yao L,Shabestary K,Björk SM,Asplund-Samuelsson J,Joensson HN,Jahn M,Hudson EP

更新日期：2020-04-03 00:00:00

abstract：:Following the discovery of high-temperature superconductivity in the La-H system, we studied the formation of new chemical compounds in the barium-hydrogen system at pressures from 75 to 173 GPa. Using in situ generation of hydrogen from NH3BH3, we synthesized previously unknown superhydride BaH12 with a pseudocubic (...

journal_title：Nature communications

authors： Chen W,Semenok DV,Kvashnin AG,Huang X,Kruglov IA,Galasso M,Song H,Duan D,Goncharov AF,Prakapenka VB,Oganov AR,Cui T

更新日期：2021-01-11 00:00:00

abstract：:Heterostructures formed by stacking layered materials require atomically clean interfaces. However, contaminants are usually trapped between the layers, aggregating into randomly located blisters, incompatible with scalable fabrication processes. Here we report a process to remove blisters from fully formed heterostru...

journal_title：Nature communications

authors： Purdie DG,Pugno NM,Taniguchi T,Watanabe K,Ferrari AC,Lombardo A

更新日期：2018-12-19 00:00:00

abstract：:High-speed light emitters integrated on silicon chips can enable novel architectures for silicon-based optoelectronics, such as on-chip optical interconnects, and silicon photonics. However, conventional light sources based on compound semiconductors face major challenges for their integration with a silicon-based pla...

journal_title：Nature communications

authors： Miyoshi Y,Fukazawa Y,Amasaka Y,Reckmann R,Yokoi T,Ishida K,Kawahara K,Ago H,Maki H

更新日期：2018-03-29 00:00:00

abstract：:Hydrogen-Deuterium eXchange coupled to Mass Spectrometry (HDX-MS) is now common practice in structural biology. However, it is most of the time applied to rather small oligomeric complexes. Here, we report on the use of HDX-MS to investigate conformational differences between the human standard 20S (std20S) and immuno...

journal_title：Nature communications

authors： Lesne J,Locard-Paulet M,Parra J,Zivković D,Menneteau T,Bousquet MP,Burlet-Schiltz O,Marcoux J

更新日期：2020-12-01 00:00:00

abstract：:The emerging monolayer transition metal dichalcogenides have provided an unprecedented material platform for miniaturized opto-electronic devices with integrated functionalities. Although excitonic light-matter interactions associated with their direct bandgaps have received tremendous research efforts, wavefront engi...

journal_title：Nature communications

authors： Qin F,Liu B,Zhu L,Lei J,Fang W,Hu D,Zhu Y,Ma W,Wang B,Shi T,Cao Y,Guan BO,Qiu CW,Lu Y,Li X

更新日期：2021-01-04 00:00:00

abstract：:Telomere maintenance is a universal hallmark of cancer. Most tumors including low-grade oligodendrogliomas use telomerase reverse transcriptase (TERT) expression for telomere maintenance while astrocytomas use the alternative lengthening of telomeres (ALT) pathway. Although TERT and ALT are hallmarks of tumor prolifer...

journal_title：Nature communications

authors： Viswanath P,Batsios G,Mukherjee J,Gillespie AM,Larson PEZ,Luchman HA,Phillips JJ,Costello JF,Pieper RO,Ronen SM

更新日期：2021-01-04 00:00:00

abstract：:Selector devices are indispensable components of large-scale nonvolatile memory and neuromorphic array systems. Besides the conventional silicon transistor, two-terminal ovonic threshold switching device with much higher scalability is currently the most industrially favored selector technology. However, current ovoni...

journal_title：Nature communications

authors： Jia S,Li H,Gotoh T,Longeaud C,Zhang B,Lyu J,Lv S,Zhu M,Song Z,Liu Q,Robertson J,Liu M

更新日期：2020-09-15 00:00:00

abstract：:Proteins and nucleic acids are sequence-regulated macromolecules with various properties originating from their perfectly sequenced primary structures. However, the sequence regulation of synthetic polymers, particularly vinyl polymers, has not been achieved and is one of the ultimate goals in polymer chemistry. In th...

journal_title：Nature communications

authors： Satoh K,Ozawa S,Mizutani M,Nagai K,Kamigaito M

更新日期：2010-04-12 00:00:00

abstract：:Precise manipulation and control of coherent lattice oscillations via nanostructuring and phonon-wave interference has the potential to significantly impact a broad array of technologies and research areas. Resolving the dynamics of individual phonons in defect-laden materials presents an enormous challenge, however, ...

journal_title：Nature communications

authors： Cremons DR,Plemmons DA,Flannigan DJ

更新日期：2016-04-15 00:00:00

abstract：:Optic atrophy 1 (OPA1) is a mitochondrial inner membrane protein that has an important role in mitochondrial fusion and structural integrity. Dysfunctional OPA1 mutations cause atrophy of the optic nerve leading to blindness. Here, we show that OPA1 has an important role in the innate immune system. Using conditional ...

journal_title：Nature communications

authors： Amini P,Stojkov D,Felser A,Jackson CB,Courage C,Schaller A,Gelman L,Soriano ME,Nuoffer JM,Scorrano L,Benarafa C,Yousefi S,Simon HU

更新日期：2018-07-27 00:00:00

abstract：:Natural systems frequently exploit intricate multiscale and multiphasic structures to achieve functionalities beyond those of man-made systems. Although understanding the chemical make-up of these systems is essential, the passive and active mechanics within biological systems are crucial when considering the many nat...

journal_title：Nature communications

authors： Egan P,Sinko R,LeDuc PR,Keten S

更新日期：2015-07-06 00:00:00

abstract：:Insects that use ephemeral resources must rapidly digest nutrients and simultaneously protect them from competitors. Here we use burying beetles (Nicrophorus vespilloides), which feed their offspring on vertebrate carrion, to investigate the digestive and defensive basis of carrion utilization. We characterize gene ex...

journal_title：Nature communications

authors： Vogel H,Shukla SP,Engl T,Weiss B,Fischer R,Steiger S,Heckel DG,Kaltenpoth M,Vilcinskas A

更新日期：2017-05-09 00:00:00

abstract：:Insulin-like growth factor 1 (IGF-1) is a critical regulator of many physiological functions, ranging from longevity to immunity. However, little is known about the role of IGF-1 in natural killer cell development and function. Here, we identify an essential role for IGF-1 in the positive regulation of human natural k...

journal_title：Nature communications

authors： Ni F,Sun R,Fu B,Wang F,Guo C,Tian Z,Wei H

更新日期：2013-01-01 00:00:00

abstract：:The ability to identify cause-effect relations is an essential component of the scientific method. The identification of causal relations is generally accomplished through statistical trials where alternative hypotheses are tested against each other. Traditionally, such trials have been based on classical statistics. ...

journal_title：Nature communications

authors： Chiribella G,Ebler D

更新日期：2019-04-01 00:00:00

abstract：:Optogenetics enables manipulation of biological processes with light at high spatio-temporal resolution to control the behavior of cells, networks, or even whole animals. In contrast to the performance of excitatory rhodopsins, the effectiveness of inhibitory optogenetic tools is still insufficient. Here we report a t...

journal_title：Nature communications

authors： Bernal Sierra YA,Rost BR,Pofahl M,Fernandes AM,Kopton RA,Moser S,Holtkamp D,Masala N,Beed P,Tukker JJ,Oldani S,Bönigk W,Kohl P,Baier H,Schneider-Warme F,Hegemann P,Beck H,Seifert R,Schmitz D

更新日期：2018-11-05 00:00:00

abstract：:The bundle of stereocilia on inner ear hair cells responds to subnanometer deflections produced by sound or head movement. Stereocilia are interconnected by a variety of links and also carry an electron-dense surface coat. The coat may contribute to stereocilia adhesion or protect from stereocilia fusion, but its mole...

journal_title：Nature communications

authors： Wu X,Ivanchenko MV,Al Jandal H,Cicconet M,Indzhykulian AA,Corey DP

更新日期：2019-08-23 00:00:00