Abstract:
:Gestational diabetes (GDM) is caused by failure of islet β cells to meet the increased insulin requirements of pregnancy. Recently, Prentice et al. (2014) discovered a 7-fold elevation of the furan fatty acid metabolite 3-carboxy-4-methyl-5-propyl-2-furanopropanoic acid (CMPF) in plasma of women with GDM and showed that CMPF directly induces β cell dysfunction.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Nolan CJdoi
10.1016/j.cmet.2014.03.020subject
Has Abstractpub_date
2014-04-01 00:00:00pages
553-4issue
4eissn
1550-4131issn
1932-7420pii
S1550-4131(14)00125-9journal_volume
19pub_type
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