Abstract：
:During conditions of impaired bile flow (cholestasis), increased serum bile acids (BAs) are prognostic markers of sepsis. In this issue, Hao et al. (2017) show that the BA receptor FXR binds NLRP3 inflammasome in macrophages and inhibits activation of inflammasome components, thus reducing endotoxemia in cholestasis.
journal_name
Cell Metabjournal_title
Cell metabolismauthors
Garcia-Irigoyen O,Moschetta Adoi
10.1016/j.cmet.2017.03.014subject
Has Abstractpub_date
2017-04-04 00:00:00pages
763-764issue
4eissn
1550-4131issn
1932-7420pii
S1550-4131(17)30166-3journal_volume
25pub_type
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