Assessing the impact of public health interventions on the transmission of pandemic H1N1 influenza a virus aboard a Peruvian navy ship.

Abstract:

BACKGROUND:Limited data exist on transmission dynamics and effectiveness of control measures for influenza in confined settings. OBJECTIVES:To investigate the transmission dynamics of a 2009 pandemic H1N1 influenza A outbreak aboard a Peruvian Navy ship and quantify the effectiveness of the implemented control measures. METHODS:We used surveillance data and a simple stochastic epidemic model to characterize and evaluate the effectiveness of control interventions implemented during an outbreak of 2009 pandemic H1N1 influenza A aboard a Peruvian Navy ship. RESULTS:The serological attack rate for the outbreak was 49·1%, with younger cadets and low-ranking officers at greater risk of infection than older, higher-ranking officers. Our transmission model yielded a good fit to the daily time series of new influenza cases by date of symptom onset. We estimated a reduction of 54·4% in the reproduction number during the period of intense control interventions. CONCLUSION:Our results indicate that the patient isolation strategy and other control measures put in place during the outbreak reduced the infectiousness of isolated individuals by 86·7%. Our findings support that early implementation of control interventions can limit the spread of influenza epidemics in confined settings.

authors

Vera DM,Hora RA,Murillo A,Wong JF,Torre AJ,Wang D,Boulay D,Hancock K,Katz JM,Ramos M,Loayza L,Quispe J,Reaves EJ,Bausch DG,Chowell G,Montgomery JM

doi

10.1111/irv.12240

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

353-9

issue

3

eissn

1750-2640

issn

1750-2659

journal_volume

8

pub_type

杂志文章
  • Evaluation of obesity as an independent risk factor for medically attended laboratory-confirmed influenza.

    abstract:BACKGROUND:The relationship between obesity and susceptibility to influenza infection in humans is unclear. Morbidly obese people were at an increased risk of complications from 2009 pandemic H1N1 influenza [A(H1N1)pdm09]. OBJECTIVE:The goal of this study was to determine whether medically attended, laboratory-confirm...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2012.00377.x

    authors: Coleman LA,Waring SC,Irving SA,Vandermause M,Shay DK,Belongia EA

    更新日期:2013-03-01 00:00:00

  • Diagnosing swine flu: the inaccuracy of case definitions during the 2009 pandemic, an attempt at refinement, and the implications for future planning.

    abstract:BACKGROUND:At the onset of the pandemic H1N1/09 influenza A outbreak in Australia, health authorities devised official clinical case definitions to guide testing and access to antiviral therapy. OBJECTIVES:To assess the diagnostic accuracy of these case definitions and to attempt to improve on them using a scoring sys...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2012.00398.x

    authors: Mahony AA,Cheng AC,Olsen KL,Aboltins CA,Black JF,Johnson PD,Lindsay Grayson M,Torresi J

    更新日期:2013-05-01 00:00:00

  • Molecular genetic characteristics of influenza A virus clinically isolated during 2011-2016 influenza seasons in Korea.

    abstract:BACKGROUND:The influenza virus is reportedly associated with 3-5 million cases of severe illness and 250 000-500 000 deaths annually worldwide. OBJECTIVES:We investigated the variation of influenza A virus in Korea and examined the association with death. METHODS:A total of 13 620 cases were enrolled in the Hospital-...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12549

    authors: Lee HS,Noh JY,Song JY,Cheong HJ,Choi WS,Jeong HW,Wie SH,Kim WJ

    更新日期:2018-07-01 00:00:00

  • Influenza antivirals currently in late-phase clinical trial.

    abstract::Influenza antiviral drugs are important for the control of influenza, most specifically for the treatment of influenza patients with severe disease following infection with a seasonal influenza virus, a newly emerging influenza strain, or in the event of a pandemic. Many influenza antivirals that are currently under i...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,评审

    doi:10.1111/irv.12446

    authors: Koszalka P,Tilmanis D,Hurt AC

    更新日期:2017-05-01 00:00:00

  • The efficacy of medical masks and respirators against respiratory infection in healthcare workers.

    abstract:OBJECTIVE:We aimed to examine the efficacy of medical masks and respirators in protecting against respiratory infections using pooled data from two homogenous randomised control clinical trials (RCTs). METHODS:The data collected on 3591 subjects in two similar RCTs conducted in Beijing, China, which examined the same ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/irv.12474

    authors: MacIntyre CR,Chughtai AA,Rahman B,Peng Y,Zhang Y,Seale H,Wang X,Wang Q

    更新日期:2017-11-01 00:00:00

  • Surveillance of influenza in Indonesia, 2003–2007.

    abstract:BACKGROUND:Longitudinal data are limited about the circulating strains of influenza viruses and their public health impact in Indonesia. We conducted influenza surveillance among outpatients and hospitalized patients with influenza-like illness (ILI) across the Indonesian archipelago from 2003 through 2007. METHODOLOG...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2012.00403.x

    authors: Kosasih H,Roselinda,Nurhayati,Klimov A,Xiyan X,Lindstrom S,Mahoney F,Beckett C,Burgess TH,Blair PJ,Uyeki TM,Sedyaningsih ER

    更新日期:2013-05-01 00:00:00

  • Whole-genome analysis of influenza A(H1N1)pdm09 viruses isolated in Uganda from 2009 to 2011.

    abstract::We report a whole-genome analysis of 19 influenza A(H1N1)pdm09 isolates from four Ugandan hospitals between 2009 and 2011. The isolates differed from the vaccine strain A/California/07/2009 by three amino acid substitutions P100S, S220T, and I338V in the hemagglutinin and by two amino acid substitutions V106I and N248...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12401

    authors: Byarugaba DK,Erima B,Millard M,Kibuuka H,Lkwago L,Bwogi J,Mimbe D,Kiconco JB,Tugume T,Mworozi EA,Turner J,Mckenzie PP,Webby RR,Webster RG,Foret C,Ducatez MF,Coldren R,Wabwire-Mangen F,Krauss S

    更新日期:2016-11-01 00:00:00

  • Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work.

    abstract::Despite the best efforts of influenza scientists, companies and health officials to prepare for the next pandemic, most of the world's people will not have access to affordable supplies of vaccines and antiviral agents. They will have to rely on 19th century public health 'technologies' to see them through. In the 21s...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1750-2659.2009.00090.x

    authors: Fedson DS

    更新日期:2009-07-01 00:00:00

  • Estimates of US influenza-associated deaths made using four different methods.

    abstract:BACKGROUND:A wide range of methods have been used for estimating influenza-associated deaths in temperate countries. Direct comparisons of estimates produced by using different models with US mortality data have not been published. OBJECTIVE:Compare estimates of US influenza-associated deaths made by using four models...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2009.00073.x

    authors: Thompson WW,Weintraub E,Dhankhar P,Cheng PY,Brammer L,Meltzer MI,Bresee JS,Shay DK

    更新日期:2009-01-01 00:00:00

  • A rapid pyrosequencing assay for the molecular detection of influenza viruses with reduced baloxavir susceptibility due to PA/I38X amino acid substitutions.

    abstract::Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high-risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following treatment. Here, we d...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12725

    authors: Koszalka P,Farrukee R,Mifsud E,Vijaykrishna D,Hurt AC

    更新日期:2020-07-01 00:00:00

  • Inactivated pandemic 2009 H1N1 influenza A virus human vaccines have different efficacy after homologous challenge in the ferret model.

    abstract:BACKGROUND:The 2009 pandemic H1N1 (A(H1N1)pdm09) influenza A virus (IAV) has replaced the previous seasonal H1N1 strain in humans and continues to circulate worldwide. The comparative performance of inactivated A(H1N1)pdm09 influenza vaccines remains of considerable interest. The objective of this study was to evaluate...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12784

    authors: Vidaña B,Brookes SM,Everett HE,Garcon F,Nuñez A,Engelhardt O,Major D,Hoschler K,Brown IH,Zambon M

    更新日期:2021-01-01 00:00:00

  • 1918 pandemic morbidity: The first wave hits the poor, the second wave hits the rich.

    abstract:BACKGROUND:Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." OBJECTIVES:To study the associations between influenz...

    journal_title:Influenza and other respiratory viruses

    pub_type: 历史文章,杂志文章

    doi:10.1111/irv.12541

    authors: Mamelund SE

    更新日期:2018-05-01 00:00:00

  • New methods for analyzing serological data with applications to influenza surveillance.

    abstract:BACKGROUND:Two important challenges to the use of serological assays for influenza surveillance include the substantial amount of experimental effort involved and the inherent noisiness of serological data. RESULTS:I show that log-transformed serological data exist in an effectively one-dimensional space. I use this r...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2010.00192.x

    authors: Ndifon W

    更新日期:2011-05-01 00:00:00

  • Genetic analysis of H3N2 influenza A viruses isolated in 2006-2007 in Nairobi, Kenya.

    abstract:BACKGROUND:Minimal influenza surveillance has been carried out in sub-Saharan Africa to provide information on circulating influenza subtypes for the purpose of vaccine production and monitoring trends in virus spread and mutations. OBJECTIVE:The aim of this study was to investigate a surveillance program in Kenya to ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2008.00044.x

    authors: Bulimo WD,Garner JL,Schnabel DC,Bedno SA,Njenga MK,Ochieng WO,Amukoye E,Magana JM,Simwa JM,Ofula VO,Lifumo SM,Wangui J,Breiman RF,Martin SK

    更新日期:2008-05-01 00:00:00

  • The 1918 influenza pandemic in New York City: age-specific timing, mortality, and transmission dynamics.

    abstract:BACKGROUND:The 1918 influenza pandemic caused disproportionately high mortality among certain age groups. The mechanisms underlying these differences are not fully understood. OBJECTIVES:To explore the dynamics of the 1918 pandemic and to identify potential age-specific transmission patterns. METHODS:We examined 1915...

    journal_title:Influenza and other respiratory viruses

    pub_type: 历史文章,杂志文章

    doi:10.1111/irv.12217

    authors: Yang W,Petkova E,Shaman J

    更新日期:2014-03-01 00:00:00

  • Respiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trials.

    abstract::As the most important viral cause of severe respiratory disease in infants and increasing recognition as important in the elderly and immunocompromised, respiratory syncytial virus (RSV) is responsible for a massive health burden worldwide. Prophylactic antibodies were successfully developed against RSV. However, thei...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,评审

    doi:10.1111/irv.12313

    authors: Broadbent L,Groves H,Shields MD,Power UF

    更新日期:2015-07-01 00:00:00

  • Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study.

    abstract:INTRODUCTION:Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS:Twenty-six countries in the Southern (n = 5) and Northern (n = 7...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12319

    authors: Caini S,Huang QS,Ciblak MA,Kusznierz G,Owen R,Wangchuk S,Henriques CM,Njouom R,Fasce RA,Yu H,Feng L,Zambon M,Clara AW,Kosasih H,Puzelli S,Kadjo HA,Emukule G,Heraud JM,Ang LW,Venter M,Mironenko A,Brammer L,Mai

    更新日期:2015-08-01 00:00:00

  • Assessment of the benefits of seasonal influenza vaccination: Elements of a framework to interpret estimates of vaccine effectiveness and support robust decision-making and communication.

    abstract::Systematic reviews and meta-analyses confirm that influenza vaccination reduces the risk of influenza illness by between about 40% and 60% in seasons when circulating influenza stains are well matched to vaccine strains. Influenza vaccine effectiveness (IVE) estimates, however, are often discordant and a source of con...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,评审

    doi:10.1111/irv.12786

    authors: Hollingsworth R,El Guerche-Séblain C,Tsai T,Vasiliev Y,Lee S,Bright H,Barbosa P

    更新日期:2021-01-01 00:00:00

  • Long-term vaccine-induced heterologous protection against H5N1 influenza viruses in the ferret model.

    abstract:BACKGROUND:Highly pathogenic H5N1 influenza viruses reemerged in humans in 2003 and have caused fatal human infections in Asia and Africa as well as ongoing outbreaks in poultry. These viruses have evolved substantially and are now so antigenically varied that a single vaccine antigen may not protect against all circul...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2012.00423.x

    authors: Ducatez MF,Webb A,Crumpton JC,Webby RJ

    更新日期:2013-07-01 00:00:00

  • Clinic accessibility and clinic-level predictors of the geographic variation in 2009 pandemic influenza vaccine coverage in Montreal, Canada.

    abstract:BACKGROUND:Nineteen mass vaccination clinics were established in Montreal, Canada, as part of the 2009 influenza A/H1N1p vaccination campaign. Although approximately 50% of the population was vaccinated, there was a considerable variation in clinic performance and community vaccine coverage. OBJECTIVE:To identify comm...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12227

    authors: Charland KM,de Montigny L,Brownstein JS,Buckeridge DL

    更新日期:2014-05-01 00:00:00

  • Parental perceptions and predictors of consent for school-located influenza vaccination in urban elementary school children in the United States.

    abstract:BACKGROUND:School-located influenza vaccination (SLV) programs have the potential to mass-vaccinate all enrolled children, but parental consent is required. OBJECTIVE:To examine parental attitudes and determine predictors of parental consent for vaccination of schoolchildren through SLV programs. PATIENTS/METHODS:Sur...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12332

    authors: Cheung S,Wang HL,Mascola L,El Amin AN,Pannaraj PS

    更新日期:2015-09-01 00:00:00

  • Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self-reported severity and duration of illness.

    abstract:BACKGROUND:A population-based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy. OBJECTIVES:We studied maternal A(H1N1)pdm09-specific hemagglutination inhibition (HI)-titer levels and waning in women with influenza-...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12623

    authors: Tunheim G,Laake I,Robertson AH,Waalen K,Hungnes O,Naess LM,Cox RJ,Mjaaland S,Trogstad L

    更新日期:2019-03-01 00:00:00

  • Influenza hospitalization epidemiology from a severe acute respiratory infection surveillance system in Jordan, January 2008-February 2014.

    abstract:BACKGROUND:Acute respiratory infections (ARIs) are a major cause of morbidity and mortality worldwide. Influenza typically contributes substantially to the burden of ARI, but only limited data are available on influenza activity and seasonality in Jordan. METHODS:Syndromic case definitions were used to identify indivi...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12354

    authors: Al-Abdallat M,Dawson P,Haddadin AJ,El-Shoubary W,Dueger E,Al-Sanouri T,Said MM,Talaat M

    更新日期:2016-03-01 00:00:00

  • Clinical implications of aminotransferase elevation in hospitalised infants aged 8-90 days with respiratory virus detection.

    abstract:BACKGROUND:Fever and respiratory symptoms are the major causes of hospitalisation in infants aged 90 days or less. Respiratory viruses (RVs) are detected by multiplex reverse transcriptase-polymerase chain reaction (mRT-PCR) in up to 70% of infants tested in this population. Aminotransferase elevation is not uncommon i...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12732

    authors: Kim SG,Oh YN,Lee JK

    更新日期:2020-07-01 00:00:00

  • Estimating influenza incidence and rates of influenza-like illness in the outpatient setting.

    abstract:BACKGROUND:Estimating influenza incidence in outpatient settings is challenging. We used outpatient healthcare practice populations as a proxy to estimate community incidence of influenza-like illness (ILI) and laboratory-confirmed influenza-associated ILI. METHODS:From October 2009 to July 2010, 38 outpatient practic...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12014

    authors: Fowlkes A,Dasgupta S,Chao E,Lemmings J,Goodin K,Harris M,Martin K,Feist M,Wu W,Boulton R,Temte J,Brammer L,Finelli L

    更新日期:2013-09-01 00:00:00

  • Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children.

    abstract:BACKGROUND:Molecular testing for viral pathogens has resulted in increasing detection of multiple viruses in respiratory secretions of ill children. The clinical impact of multiple virus infections on clinical presentation and outcome is unclear. OBJECTIVES:To compare clinical characteristics and viral load between ch...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2011.00265.x

    authors: Martin ET,Kuypers J,Wald A,Englund JA

    更新日期:2012-01-01 00:00:00

  • Estimating the hospitalization burden associated with influenza and respiratory syncytial virus in New York City, 2003-2011.

    abstract:BACKGROUND:Hospitalization burden associated with influenza and respiratory syncytial virus (RSV) is uncertain due to ambiguity in the inference methodologies employed for its estimation. OBJECTIVES:Utilization of a new method to quantitate the above burden. METHODS:Weekly hospitalization rates for several principal ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12325

    authors: Goldstein E,Greene SK,Olson DR,Hanage WP,Lipsitch M

    更新日期:2015-09-01 00:00:00

  • Influenza vaccination coverage and effectiveness in young children in Thailand, 2011-2013.

    abstract:BACKGROUND:Since 2009, Thailand has recommended influenza vaccine for children aged 6 months through 2 years, but no estimates of influenza vaccine coverage or effectiveness are available for this target group. METHODS:During August 2011-May 2013, high-risk and healthy children aged ≤36 months were enrolled in a 2-yea...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12302

    authors: Kittikraisak W,Suntarattiwong P,Levy J,Fernandez S,Dawood FS,Olsen SJ,Chotpitayasunondh T

    更新日期:2015-03-01 00:00:00

  • Influence of meteorological parameters in the seasonality of influenza viruses circulating in Northern Cameroon.

    abstract:BACKGROUND:Several studies have demonstrated the role of meteorological parameters in the seasonality of influenza viruses in tropical and subtropical regions, most importantly temperature, humidity, and rainfall. OBJECTIVES:This study aimed to describe the influence of meteorological parameters in the seasonality of ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12612

    authors: Munshili Njifon HL,Monamele CG,Kengne Nde C,Vernet MA,Bouba G,Tchatchouang S,Njankouo MR,Tapondjou R,Deweerdt L,Mbacham W,Njouom R

    更新日期:2019-03-01 00:00:00

  • The Influenza Primer Design Resource: a new tool for translating influenza sequence data into effective diagnostics.

    abstract:BACKGROUND:Recent outbreaks of highly pathogenic avian influenza and multiple occurrences of zoonotic infection and deaths in humans have sparked a dramatic increase in influenza research. In order to rapidly identify and help prevent future influenza outbreaks, numerous laboratories around the world are working to dev...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2007.00031.x

    authors: Bose ME,Littrell JC,Patzer AD,Kraft AJ,Metallo JA,Fan J,Henrickson KJ

    更新日期:2008-01-01 00:00:00