Long-term vaccine-induced heterologous protection against H5N1 influenza viruses in the ferret model.

abstract：BACKGROUND:A population-based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy. OBJECTIVES:We studied maternal A(H1N1)pdm09-specific hemagglutination inhibition (HI)-titer levels and waning in women with influenza-...

journal_title：Influenza and other respiratory viruses

authors： Tunheim G,Laake I,Robertson AH,Waalen K,Hungnes O,Naess LM,Cox RJ,Mjaaland S,Trogstad L

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Fever and respiratory symptoms are the major causes of hospitalisation in infants aged 90 days or less. Respiratory viruses (RVs) are detected by multiplex reverse transcriptase-polymerase chain reaction (mRT-PCR) in up to 70% of infants tested in this population. Aminotransferase elevation is not uncommon i...

journal_title：Influenza and other respiratory viruses

authors： Kim SG,Oh YN,Lee JK

更新日期：2020-07-01 00:00:00

abstract：:Systematic reviews and meta-analyses confirm that influenza vaccination reduces the risk of influenza illness by between about 40% and 60% in seasons when circulating influenza stains are well matched to vaccine strains. Influenza vaccine effectiveness (IVE) estimates, however, are often discordant and a source of con...

journal_title：Influenza and other respiratory viruses

authors： Hollingsworth R,El Guerche-Séblain C,Tsai T,Vasiliev Y,Lee S,Bright H,Barbosa P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Acute respiratory infections are a leading cause of morbidity and mortality worldwide. Starting in 2009, pandemic influenza A(H1N1) 2009 virus has become one of the leading respiratory pathogens worldwide. However, the overall impact of this virus as a cause of mortality has not been clearly defined. OBJECT...

journal_title：Influenza and other respiratory viruses

authors： Comas-García A,García-Sepúlveda CA,Méndez-de Lira JJ,Aranda-Romo S,Hernández-Salinas AE,Noyola DE

更新日期：2011-03-01 00:00:00

abstract：:A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection (ARI) and in number of lethal cases. We performed antigenic analysis of 108 and whole-genome sequencing of 77 influenza A(H1N1)pdm0...

journal_title：Influenza and other respiratory viruses

authors： Komissarov A,Fadeev A,Sergeeva M,Petrov S,Sintsova K,Egorova A,Pisareva M,Buzitskaya Z,Musaeva T,Danilenko D,Konovalova N,Petrova P,Stolyarov K,Smorodintseva E,Burtseva E,Krasnoslobodtsev K,Kirillova E,Karpova L,Eropk

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:A point-of-care rapid test (POCRT) may help early and targeted use of antiviral drugs for the management of influenza A infection. OBJECTIVE:(i) To determine whether antiviral treatment based on a POCRT for influenza A is cost-effective and, (ii) to determine the thresholds of key test parameters (sensitivi...

journal_title：Influenza and other respiratory viruses

authors： Nshimyumukiza L,Douville X,Fournier D,Duplantie J,Daher RK,Charlebois I,Longtin J,Papenburg J,Guay M,Boissinot M,Bergeron MG,Boudreau D,Gagné C,Rousseau F,Reinharz D

更新日期：2016-03-01 00:00:00

abstract：:Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high-risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following treatment. Here, we d...

journal_title：Influenza and other respiratory viruses

authors： Koszalka P,Farrukee R,Mifsud E,Vijaykrishna D,Hurt AC

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sial...

journal_title：Influenza and other respiratory viruses

authors： Sandbulte MR,Gao J,Straight TM,Eichelberger MC

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:The goal of this investigation was to determine if acute influenza infection is associated with depletion of CoQ10 compared to healthy controls and to determine any associations between CoQ10 levels and illness severity and inflammatory biomarkers. PATIENTS AND METHODS:We analyzed serum CoQ10 concentrations...

journal_title：Influenza and other respiratory viruses

authors： Chase M,Cocchi MN,Liu X,Andersen LW,Holmberg MJ,Donnino MW

更新日期：2019-01-01 00:00:00

abstract：:We report a whole-genome analysis of 19 influenza A(H1N1)pdm09 isolates from four Ugandan hospitals between 2009 and 2011. The isolates differed from the vaccine strain A/California/07/2009 by three amino acid substitutions P100S, S220T, and I338V in the hemagglutinin and by two amino acid substitutions V106I and N248...

journal_title：Influenza and other respiratory viruses

authors： Byarugaba DK,Erima B,Millard M,Kibuuka H,Lkwago L,Bwogi J,Mimbe D,Kiconco JB,Tugume T,Mworozi EA,Turner J,Mckenzie PP,Webby RR,Webster RG,Foret C,Ducatez MF,Coldren R,Wabwire-Mangen F,Krauss S

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Influenza A(H3N2), A(H1N1)pdm09 and B viruses co-circulated in Europe in 2017-18, predominated by influenza B. WHO-recommended, trivalent vaccine components were lineage-mismatched for B. The I-MOVE hospital network measured 2017-18 seasonal influenza vaccine effectiveness (IVE) against influenza A(H3N2) and...

journal_title：Influenza and other respiratory viruses

authors： Rose AMC,Kissling E,Gherasim A,Casado I,Bella A,Launay O,Lazăr M,Marbus S,Kuliese M,Syrjänen R,Machado A,Kurečić Filipović S,Larrauri A,Castilla J,Alfonsi V,Galtier F,Ivanciuc A,Meijer A,Mickiene A,Ikonen N,Gómez

更新日期：2020-05-01 00:00:00

abstract：:When the influenza A (H1N1) pandemic spread across the globe from April 2009 to August 2010, many WHO Member States used antiviral drugs, specifically neuraminidase inhibitors (NAIs) oseltamivir and zanamivir, to treat influenza patients in critical condition. Antivirals have been found to be effective in reducing sev...

journal_title：Influenza and other respiratory viruses

authors： Miller PE,Rambachan A,Hubbard RJ,Li J,Meyer AE,Stephens P,Mounts AW,Rolfes MA,Penn CR

更新日期：2013-09-01 00:00:00

abstract：:An outbreak of highly pathogenic avian influenza A (H5N6) virus occurred between November 20, 2016, and March 1, 2017 in poultry farms, in the Gyeonggi Province, Republic of Korea. To identify the risk of transmission of H5N6 to depopulation workers, active and passive surveillance was conducted. Virological testing o...

journal_title：Influenza and other respiratory viruses

authors： Ryu S,Lim JS,Cowling BJ,Chun BC

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The 1918 influenza pandemic caused disproportionately high mortality among certain age groups. The mechanisms underlying these differences are not fully understood. OBJECTIVES:To explore the dynamics of the 1918 pandemic and to identify potential age-specific transmission patterns. METHODS:We examined 1915...

journal_title：Influenza and other respiratory viruses

authors： Yang W,Petkova E,Shaman J

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:This study evaluated the diagnostic value of measuring the levels of procalcitonin (PCT) and C-reactive protein (CRP) to differentiate children co-infected with H1N1 influenza and bacteria from children infected with H1N1 influenza alone. METHODS:Consecutive patients (children aged < 5 years) with laboratory...

journal_title：Influenza and other respiratory viruses

authors： Li Z,He L,Li S,He W,Zha C,Ou W,Hou Q,Wang W,Sun X,Liang H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." OBJECTIVES:To study the associations between influenz...

journal_title：Influenza and other respiratory viruses

authors： Mamelund SE

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:We aimed to examine the efficacy of medical masks and respirators in protecting against respiratory infections using pooled data from two homogenous randomised control clinical trials (RCTs). METHODS:The data collected on 3591 subjects in two similar RCTs conducted in Beijing, China, which examined the same ...

journal_title：Influenza and other respiratory viruses

authors： MacIntyre CR,Chughtai AA,Rahman B,Peng Y,Zhang Y,Seale H,Wang X,Wang Q

更新日期：2017-11-01 00:00:00

abstract：:This study used Poisson regression modelling to estimate influenza-associated mortality in New Zealand for 1990-2008. Inputs were weekly numbers of deaths and influenza and RSV isolates. Seasonal influenza was associated with an average of 401 medical deaths annually from 1990 to 2008, a rate of 10.6 (95% CI: 7.9, 13....

journal_title：Influenza and other respiratory viruses

authors： Kessaram T,Stanley J,Baker MG

更新日期：2015-01-01 00:00:00

abstract：:Oseltamivir-resistant 2009 H1N1 influenza virus infections associated with neuraminidase (NA) H275Y have been identified sporadically. Strains possessing the hemagglutinin (HA) D222G mutation have been detected in small numbers of fatal 2009 H1N1 cases. We report the first clinical description of 2009 H1N1 virus infec...

journal_title：Influenza and other respiratory viruses

authors： DeVries A,Wotton J,Lees C,Boxrud D,Uyeki T,Lynfield R

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Equine influenza (EI) is a highly contagious respiratory disease of horses. OBJECTIVES:The aim of this study was to evaluate two rapid antigen detection kits (Directigen or DFA, and Espline) and a commercial ELISA for the detection of EI nucleoprotein in nasal swabs. METHOD:Nasal swab samples from naturall...

journal_title：Influenza and other respiratory viruses

authors： Galvin P,Gildea S,Nelly M,Quinlivan M,Arkins S,Walsh C,Cullinane A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The genetic and antigenic characteristics of influenza A viruses (IAV) within and between species change over time due to antigenic shift and drift. Although pigs are known to play a key role in the epidemiology of IAV between species, little is known about the molecular evolution of IAV hemagglutinin (HA) i...

journal_title：Influenza and other respiratory viruses

authors： Diaz A,Allerson M,Culhane M,Sreevatsan S,Torremorell M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Data about influenza mortality burden in northern China are limited. This study estimated mortality burden in Beijing associated with seasonal influenza from 2007 to 2013 and the 2009 H1N1 pandemic. METHODS:We estimated influenza-associated excess mortality by fitting a negative binomial model using weekly ...

journal_title：Influenza and other respiratory viruses

authors： Wu S,Wei Z,Greene CM,Yang P,Su J,Song Y,Iuliano AD,Wang Q

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Influenza vaccine coverage rates among healthcare workers (HCWs) in acute care facilities in Canada remain below national targets. OBJECTIVE:To determine factors associated with influenza vaccine uptake among HCWs. METHODS:This secondary analysis of a prospective cohort study included HCWs aged 18-69 years...

journal_title：Influenza and other respiratory viruses

authors： Hussain H,McGeer A,McNeil S,Katz K,Loeb M,Simor A,Powis J,Langley J,Muller M,Canadian Health Care Worker Study Group.,Coleman BL

更新日期：2018-05-01 00:00:00

abstract：:The emergence of a novel swine-origin pandemic influenza virus in 2009, together with the continuing circulation of highly pathogenic avian H5N1 viruses and the urgent global need to produce effective vaccines against such public health threats, has prompted a renewed interest in improving our understanding of the imm...

journal_title：Influenza and other respiratory viruses

authors： Haaheim LR,Katz JM

更新日期：2011-07-01 00:00:00

abstract：:Within a hand-washing clinical trial, we evaluated factors associated with fomite contamination in households with an influenza-infected child. Influenza virus RNA contamination was higher in households with low absolute humidity and in control households, suggesting that hand washing reduces surface contamination. ...

journal_title：Influenza and other respiratory viruses

authors： Levy JW,Suntarattiwong P,Simmerman JM,Jarman RG,Johnson K,Olsen SJ,Chotpitayasunondh T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUNDS:Influenza can spread rapidly in long-term care facilities (LTCFs), and residents are usually at higher risk for influenza infections. OBJECTIVE:Our study aimed to evaluate the effectiveness of antiviral interventions on outbreak control. METHODS:Taiwan Centers for Disease Control used a syndromic surveill...

journal_title：Influenza and other respiratory viruses

authors： Cheng HY,Chen WC,Chou YJ,Huang AS,Huang WT

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:We determined influenza A(H1N1)pdm09 antibody levels before and after the first wave of the pandemic in an urban community in Dhaka, Bangladesh. METHODS:We identified a cohort of households by stratified random sampling. We collected baseline serum specimens during July-August 2009, just prior to the initia...

journal_title：Influenza and other respiratory viruses

authors： Nasreen S,Rahman M,Hancock K,Katz JM,Goswami D,Sturm-Ramirez K,Holiday C,Jefferson S,Branch A,Wang D,Veguilla V,Widdowson MA,Fry AM,Brooks WA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The goal of this double-blind, randomized, controlled clinical trial was to assess the safety and immunogenicity of two different doses of a monovalent split-virion 2009 pandemic influenza A/H1N1 vaccine without adjuvant in Chinese infants aged 6-35 months. DESIGN AND SETTING  Subjects were randomly assigned...

journal_title：Influenza and other respiratory viruses

authors： Li YP,Li W,Liang XF,Liu Y,Huang XC,Li CG,Li RC,Wang JZ,Wang HQ,Yin WD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:It appears inter-seasonal influenza notifications have been increasing in summer months in Australia. This study aims to determine changes in inter-seasonal influenza activity in Australia over time. METHODS:Routine influenza surveillance data and hospitalisations data were analysed to study the epidemiolog...

journal_title：Influenza and other respiratory viruses

authors： Moa AM,Adam DC,MacIntyre CR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a leading etiological agent of acute respiratory tract infections and hospitalizations in children. However, little information is available regarding RSV infections in Latin American countries, particularly among adult patients. OBJECTIVE:To describe the epidemiology of...

journal_title：Influenza and other respiratory viruses

authors： Gamiño-Arroyo AE,Moreno-Espinosa S,Llamosas-Gallardo B,Ortiz-Hernández AA,Guerrero ML,Galindo-Fraga A,Galán-Herrera JF,Prado-Galbarro FJ,Beigel JH,Ruiz-Palacios GM,Noyola DE,Mexico Emerging Infectious Diseases Clinical Research Net

更新日期：2017-01-01 00:00:00