The 1918 influenza pandemic in New York City: age-specific timing, mortality, and transmission dynamics.

abstract：:A myriad of risk factors have been linked to an increase in the severity of the pandemic H1N1 2009 influenza A virus [A(H1N1)pdm09] including pregnancy and obesity where death rates can be elevated as compared to the general population. The goal of this review is to provide an overview of the influence of pregnancy an...

journal_title：Influenza and other respiratory viruses

authors： Karlsson EA,Marcelin G,Webby RJ,Schultz-Cherry S

更新日期：2012-11-01 00:00:00

abstract：:Sinovac Biotech started to develop prototype pandemic influenza H5N1 vaccines in March 2004. On 2 April 2008, Sinovac's inactivated, aluminium-adjuvanted, whole-virion prototype pandemic influenza A (H5N1) vaccine (PanFlu) was granted production licensure by the China regulatory authority State Food and Drug Administr...

journal_title：Influenza and other respiratory viruses

authors： Qiu YZ,Yin WD

更新日期：2008-11-01 00:00:00

abstract：:We consider the net benefits of pre-dispensing antivirals to high-risk individuals during an influenza pandemic, where the measure of the benefit is the number of severe outcomes (such as deaths or hospitalizations) prevented by antivirals in the whole population. One potential benefit of pre-dispensing is that indivi...

journal_title：Influenza and other respiratory viruses

authors： Goldstein E,Miller JC,O'Hagan JJ,Lipsitch M

更新日期：2010-03-01 00:00:00

abstract：:Systematic reviews and meta-analyses confirm that influenza vaccination reduces the risk of influenza illness by between about 40% and 60% in seasons when circulating influenza stains are well matched to vaccine strains. Influenza vaccine effectiveness (IVE) estimates, however, are often discordant and a source of con...

journal_title：Influenza and other respiratory viruses

authors： Hollingsworth R,El Guerche-Séblain C,Tsai T,Vasiliev Y,Lee S,Bright H,Barbosa P

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are particularly relevant in influenza vaccine trials in the elderly where reduction in symptom severity could prevent illness-related functional impairment. OBJECTIVES:To evaluate PROs in people aged ≥ 65 years receiving two different vaccines. METHODS:This was a phase III...

journal_title：Influenza and other respiratory viruses

authors： van Essen GA,Beran J,Devaster JM,Durand C,Duval X,Esen M,Falsey AR,Feldman G,Gervais P,Innis BL,Kovac M,Launay O,Leroux-Roels G,McElhaney JE,McNeil S,Oujaa M,Richardus JH,Ruiz-Palacios G,Osborne RH,Oostvogels L

更新日期：2014-07-01 00:00:00

abstract：:We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when c...

journal_title：Influenza and other respiratory viruses

authors： Martin ET,Archer C,McRoberts J,Kulik J,Thurston T,Lephart P,Kaye KS

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Estimating influenza incidence in outpatient settings is challenging. We used outpatient healthcare practice populations as a proxy to estimate community incidence of influenza-like illness (ILI) and laboratory-confirmed influenza-associated ILI. METHODS:From October 2009 to July 2010, 38 outpatient practic...

journal_title：Influenza and other respiratory viruses

authors： Fowlkes A,Dasgupta S,Chao E,Lemmings J,Goodin K,Harris M,Martin K,Feist M,Wu W,Boulton R,Temte J,Brammer L,Finelli L

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Respiratory tract infections are a major cause of outpatient visits, yet only a portion is tested to determine the etiologic organism. Multiplex reverse transcriptase polymerase chain reaction (MRT-PCR) assays for detection of multiple viruses are being used increasingly in clinical settings. METHODS:During...

journal_title：Influenza and other respiratory viruses

authors： Zimmerman RK,Rinaldo CR,Nowalk MP,Gk B,Thompson MG,Moehling KK,Bullotta A,Wisniewski S

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Although it is known that febrile respiratory illnesses (FRI) may be caused by multiple respiratory pathogens, there are no population-level studies describing its impact on clinical disease. METHODS:Between May 2009 and October 2012, 7733 FRI patients and controls in the Singapore military had clinical dat...

journal_title：Influenza and other respiratory viruses

authors： Ho ZJ,Zhao X,Cook AR,Loh JP,Ng SH,Tan BH,Lee VJ

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a leading etiological agent of acute respiratory tract infections and hospitalizations in children. However, little information is available regarding RSV infections in Latin American countries, particularly among adult patients. OBJECTIVE:To describe the epidemiology of...

journal_title：Influenza and other respiratory viruses

authors： Gamiño-Arroyo AE,Moreno-Espinosa S,Llamosas-Gallardo B,Ortiz-Hernández AA,Guerrero ML,Galindo-Fraga A,Galán-Herrera JF,Prado-Galbarro FJ,Beigel JH,Ruiz-Palacios GM,Noyola DE,Mexico Emerging Infectious Diseases Clinical Research Net

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." OBJECTIVES:To study the associations between influenz...

journal_title：Influenza and other respiratory viruses

authors： Mamelund SE

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Lower respiratory tract illness is a major cause of morbidity and mortality in children worldwide, however, information about the epidemiological and clinical characteristics of LRTIs caused by HMPV and HBoV in China is limited. OBJECTIVES:Human bocavirus (HBoV) and human metapneumovirus (HMPV) are two impo...

journal_title：Influenza and other respiratory viruses

authors： Zhou JY,Peng Y,Peng XY,Gao HC,Sun YP,Xie LY,Zhong LL,Duan ZJ,Xie ZP,Cao YD

更新日期：2018-03-01 00:00:00

abstract：:Within a hand-washing clinical trial, we evaluated factors associated with fomite contamination in households with an influenza-infected child. Influenza virus RNA contamination was higher in households with low absolute humidity and in control households, suggesting that hand washing reduces surface contamination. ...

journal_title：Influenza and other respiratory viruses

authors： Levy JW,Suntarattiwong P,Simmerman JM,Jarman RG,Johnson K,Olsen SJ,Chotpitayasunondh T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The influenza virus is reportedly associated with 3-5 million cases of severe illness and 250 000-500 000 deaths annually worldwide. OBJECTIVES:We investigated the variation of influenza A virus in Korea and examined the association with death. METHODS:A total of 13 620 cases were enrolled in the Hospital-...

journal_title：Influenza and other respiratory viruses

authors： Lee HS,Noh JY,Song JY,Cheong HJ,Choi WS,Jeong HW,Wie SH,Kim WJ

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Influenza surveillance helps time prevention and control interventions especially where complex seasonal patterns exist. We assessed influenza surveillance sustainability in Africa where influenza activity varies and external funds for surveillance have decreased. METHODS:We surveyed African Network for Inf...

journal_title：Influenza and other respiratory viruses

authors： Igboh LS,McMorrow M,Tempia S,Emukule GO,Talla Nzussouo N,McCarron M,Williams T,Weatherspoon V,Moen A,Fawzi D,Njouom R,Nakoune E,Dauoda C,Kavunga-Membo H,Okeyo M,Heraud JM,Mambule IK,Sow SO,Tivane A,Lagare A,Adebay

更新日期：2020-11-04 00:00:00

abstract：BACKGROUND:A point-of-care rapid test (POCRT) may help early and targeted use of antiviral drugs for the management of influenza A infection. OBJECTIVE:(i) To determine whether antiviral treatment based on a POCRT for influenza A is cost-effective and, (ii) to determine the thresholds of key test parameters (sensitivi...

journal_title：Influenza and other respiratory viruses

authors： Nshimyumukiza L,Douville X,Fournier D,Duplantie J,Daher RK,Charlebois I,Longtin J,Papenburg J,Guay M,Boissinot M,Bergeron MG,Boudreau D,Gagné C,Rousseau F,Reinharz D

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The genetic and antigenic characteristics of influenza A viruses (IAV) within and between species change over time due to antigenic shift and drift. Although pigs are known to play a key role in the epidemiology of IAV between species, little is known about the molecular evolution of IAV hemagglutinin (HA) i...

journal_title：Influenza and other respiratory viruses

authors： Diaz A,Allerson M,Culhane M,Sreevatsan S,Torremorell M

更新日期：2013-12-01 00:00:00

abstract：:The emergence of a novel swine-origin pandemic influenza virus in 2009, together with the continuing circulation of highly pathogenic avian H5N1 viruses and the urgent global need to produce effective vaccines against such public health threats, has prompted a renewed interest in improving our understanding of the imm...

journal_title：Influenza and other respiratory viruses

authors： Haaheim LR,Katz JM

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Human bocavirus (HBoV) is a novel parvovirus that is associated with respiratory and gastrointestinal tract disease. OBJECTIVES:To investigate the prevalence and genetic diversity of HBoV amongst hospitalized patients with acute lower respiratory infection (ALRI) in Cambodia. STUDY DESIGN:  Samples were co...

journal_title：Influenza and other respiratory viruses

authors： Arnott A,Vong S,Rith S,Naughtin M,Ly S,Guillard B,Deubel V,Buchy P

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Reviews of the global response to the 2009 pandemic of influenza A/H1N1 affirmed the importance of assessment of preparedness and response capabilities. DESIGN:The U. S. Centers for Disease Control and Prevention (CDC) and partners developed the National Inventory of Core Capabilities for Pandemic Influenza...

journal_title：Influenza and other respiratory viruses

authors： MacDonald G,Moen AC,St Louis ME

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Pregnant women have an elevated risk of illness and hospitalisation from influenza. Pregnant women are recommended to be prioritised for influenza vaccination during any stage of pregnancy. The risk of seasonal influenza varies substantially throughout the year in temperate climates; however, there is limite...

journal_title：Influenza and other respiratory viruses

authors： Cuningham W,Geard N,Fielding JE,Braat S,Madhi SA,Nunes MC,Christian LM,Lin SY,Lee CN,Yamaguchi K,Bisgaard H,Chawes B,Chao AS,Blanchard-Rohner G,Schlaudecker EP,Fisher BM,McVernon J,Moss R

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Given their medical vulnerabilities, we investigated the epidemiological factors related to H1N1 infection in school-aged children. METHODS:This study analyzed data collected on 7448 school-aged children in South Korea between 18 November and 8 December 2009. RESULTS:We found that H1N1 infection was associa...

journal_title：Influenza and other respiratory viruses

authors： Kim CO,Nam CM,Lee DC,Chang J,Lee JW

更新日期：2012-09-01 00:00:00

abstract：:A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection (ARI) and in number of lethal cases. We performed antigenic analysis of 108 and whole-genome sequencing of 77 influenza A(H1N1)pdm0...

journal_title：Influenza and other respiratory viruses

authors： Komissarov A,Fadeev A,Sergeeva M,Petrov S,Sintsova K,Egorova A,Pisareva M,Buzitskaya Z,Musaeva T,Danilenko D,Konovalova N,Petrova P,Stolyarov K,Smorodintseva E,Burtseva E,Krasnoslobodtsev K,Kirillova E,Karpova L,Eropk

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Two important challenges to the use of serological assays for influenza surveillance include the substantial amount of experimental effort involved and the inherent noisiness of serological data. RESULTS:I show that log-transformed serological data exist in an effectively one-dimensional space. I use this r...

journal_title：Influenza and other respiratory viruses

authors： Ndifon W

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Acute respiratory infections are a leading cause of morbidity and mortality worldwide. Starting in 2009, pandemic influenza A(H1N1) 2009 virus has become one of the leading respiratory pathogens worldwide. However, the overall impact of this virus as a cause of mortality has not been clearly defined. OBJECT...

journal_title：Influenza and other respiratory viruses

authors： Comas-García A,García-Sepúlveda CA,Méndez-de Lira JJ,Aranda-Romo S,Hernández-Salinas AE,Noyola DE

更新日期：2011-03-01 00:00:00

abstract：:Highly pathogenic avian influenza A H5N1 viruses remain a significant health threat to humans given the continued rare occurrence of human cases with a high case fatality rate. This brief literature review summarizes available evidence of risk factors for H5N1 infection in humans and updates a recent systematic review...

journal_title：Influenza and other respiratory viruses

authors： Van Kerkhove MD

更新日期：2013-09-01 00:00:00

abstract：:This study used Poisson regression modelling to estimate influenza-associated mortality in New Zealand for 1990-2008. Inputs were weekly numbers of deaths and influenza and RSV isolates. Seasonal influenza was associated with an average of 401 medical deaths annually from 1990 to 2008, a rate of 10.6 (95% CI: 7.9, 13....

journal_title：Influenza and other respiratory viruses

authors： Kessaram T,Stanley J,Baker MG

更新日期：2015-01-01 00:00:00

abstract：:Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high-risk individuals infected with influenza. Viruses with reduced baloxavir susceptibility due to amino acid substitutions at residue 38 of the PA have been detected in some individuals following treatment. Here, we d...

journal_title：Influenza and other respiratory viruses

authors： Koszalka P,Farrukee R,Mifsud E,Vijaykrishna D,Hurt AC

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Molecular testing for viral pathogens has resulted in increasing detection of multiple viruses in respiratory secretions of ill children. The clinical impact of multiple virus infections on clinical presentation and outcome is unclear. OBJECTIVES:To compare clinical characteristics and viral load between ch...

journal_title：Influenza and other respiratory viruses

authors： Martin ET,Kuypers J,Wald A,Englund JA

更新日期：2012-01-01 00:00:00

abstract：:When the influenza A (H1N1) pandemic spread across the globe from April 2009 to August 2010, many WHO Member States used antiviral drugs, specifically neuraminidase inhibitors (NAIs) oseltamivir and zanamivir, to treat influenza patients in critical condition. Antivirals have been found to be effective in reducing sev...

journal_title：Influenza and other respiratory viruses

authors： Miller PE,Rambachan A,Hubbard RJ,Li J,Meyer AE,Stephens P,Mounts AW,Rolfes MA,Penn CR

更新日期：2013-09-01 00:00:00