Abstract:
BACKGROUND:A wide range of methods have been used for estimating influenza-associated deaths in temperate countries. Direct comparisons of estimates produced by using different models with US mortality data have not been published. OBJECTIVE:Compare estimates of US influenza-associated deaths made by using four models and summarize strengths and weaknesses of each model. METHODS:US mortality data from the 1972-1973 through 2002-2003 respiratory seasons and World Health Organization influenza surveillance data were used to estimate influenza-associated respiratory and circulatory deaths. Four models were used: (i) rate-difference (using peri-season or summer-season baselines), (ii) Serfling least squares cyclical regression, (iii) Serfling-Poisson regression, (iv) and autoregressive integrated moving average models. RESULTS:Annual estimates of influenza-associated deaths made using each model were similar and positively correlated, except for estimates from the summer-season rate-difference model, which were consistently higher. From the 1976/1977 through the 2002/2003 seasons the, the Poisson regression models estimated that an annual average of 25,470 [95% confidence interval (CI) 19,781-31,159] influenza-associated respiratory and circulatory deaths [9.9 deaths per 100,000 (95% CI 7.9-11.9)], while peri-season rate-difference models using a 15% threshold estimated an annual average of 22,454 (95% CI 16,189-28,719) deaths [8.6 deaths per 100,000 (95% CI 6.4-10.9)]. CONCLUSIONS:Estimates of influenza-associated mortality were of similar magnitude. Poisson regression models permit the estimation of deaths associated with influenza A and B, but require robust viral surveillance data. By contrast, simple peri-season rate-difference models may prove useful for estimating mortality in countries with sparse viral surveillance data or complex influenza seasonality.
journal_name
Influenza Other Respir Virusesjournal_title
Influenza and other respiratory virusesauthors
Thompson WW,Weintraub E,Dhankhar P,Cheng PY,Brammer L,Meltzer MI,Bresee JS,Shay DKdoi
10.1111/j.1750-2659.2009.00073.xsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
37-49issue
1eissn
1750-2640issn
1750-2659pii
IRV073journal_volume
3pub_type
杂志文章abstract:BACKGROUND:A single case of novel influenza A (H1N1) 09 infection was identified by PCR among a New Zealand high-school group that toured California in April 2009. Close monitoring of the tour group and their New Zealand contacts identified 11 other tour members with respiratory symptoms who were investigated. In all n...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验,评审
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journal_title:Influenza and other respiratory viruses
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 历史文章,杂志文章
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00256.x
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
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更新日期:2013-09-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Influenza and other respiratory viruses
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doi:10.1111/j.1750-2659.2012.00423.x
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12157
更新日期:2013-11-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12138
更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12321
更新日期:2015-07-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12793
更新日期:2021-01-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验
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更新日期:2013-09-01 00:00:00
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更新日期:2020-07-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00322.x
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pub_type: 杂志文章
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